The present study was conducted to investigate the involvement of nitric oxide (NO) in cumulus expansion, oocyte mortality and meiotic maturation of porcine cumulus enclosed oocytes (CEOs) cultured in two different models when gonadotropins, including follicle-stimulating hormone (FSH) and human chorionic gonadotropin (hCG) were presented or not. And the interaction between NO and $\beta$-mercaptoethanol ($\beta$-ME), a free radical scavenger was also investigated. Two models refer to spontaneous maturation model and hypoxanthine (HX) medium model. All the 3,433 eligible CEOs were incubated at $39^{\circ}C$ and the cumulus expansion, oocyte morphology and nuclear phase were evaluated 44 h after incubation. (1) In spontaneous maturation model, NO stimulates the cumulus expansion and $\beta$-ME delayed it. NO doesn't affect the oocyte meiotic resumption but inhibits the oocytes to develop to metaphase II. (2) In HX medium model, NO or $\beta$-ME doesn't affect the expansion in the absence of gonadotropins, but in the presence of gonadotropins, NO or $\beta$-ME inhibits the expansion. In the presence of gonadotropins, NO inhibits the oocyte meiotic resumption and it especially inhibits the oocyte to develop to metaphase II, and $\beta$-ME reverses such inhibitory effects. The cooperation of gonadotropins and $\beta$-ME stimulates the meiotic resumption and especially, promotes the CEOs to develop to metaphase II in both models. Moreover, HX might contribute to the fragility of oocyte zona pellucida and gonadotropins, nitric oxide and $\beta$-ME could alleviate it separately, and cooperatively. It is concluded that NO exerts different functions in two models and $\beta$-ME affected the functions of NO in different models.
In this study, the influence of the CEOs' characteristics on the technology innovation performances of IT venture companies was analyzed. The relation between business performance and the characteristics of CEOs has been dealt with in earlier studies, but most paid attention to financial perspective, and few of these focused on the influence of managers on technology innovation. On the other hand, most of the studies related to the role of managers in technology innovation mainly focused on R&D investment and research infrastructure but did not delve on the characteristics of them in an in-depth way. In this study, the characteristics of CEOs and their technology innovation performances were empirically analyzed based on the results of a recently conducted survey on the IT venture companies. In the analytical aspect, a negative binominal model was applied to solve the over-dispersion problem that often appears in the count variable analysis. As a result, it was found that major, work type, and work experience, among managers' characteristics, have significant influences on managers' technology innovation performances, along with the company's innovation capacity, technological competitiveness, market competition, and support from the government.
Objectives : To investigate the current status of hospital-based health promotion programs in Korea and to elucidate the factors which affect to the process of implementation. Methods : We conducted a mail survey of all 875 hospitals in Korea from March to May 2001. In reference to 12 specific kinds of health promotion programs, hospital CEOs were asked whether their hospital have such programs, whether they are fully staffed and whether the program is paid for by the patients. Contextual factors(location, hospital type, number of beds, length of operation, public/private status, economic level of the community, the level of competition) and organizational factors (the extent of market, compatibility with vision, formalization), strategic types of the CEOs (defender/analyser/prospector) were also surveyed. The relationships between each variable and the implementation of health promotion services, activation of services, and the target groups(patient/community resident) were analyzed by univariate analysis and the independent effects of these variables were examined with multiple logistic regression. Results : 100 of 125 hospitals responding (84.8%) had mere than one health promotion program. However, they showed fluctuations in the adoption rate of each programs, meaning that comprehensive health promotion services were not provided. Many programs were not fully staffed and few hospitals had paid programs. In factors affecting health promotion service implementation, private hospitals showed a higher rate in implementation than public hospitals. In contrast, when the competition among nearby hospitals was intense, the level of implementation of service lowered. In the strategic type of the CEOs, the prospectors were shown to have instituted more health promotion programs in their hospitals and the analysers had a greater tendency to have programs for community residents than the defenders. Conclusion . Considering the above results, contextual factors may contribute greatly to the introduction of health promotion services in Korean hospital, although the CEO's personal preference and organizational factors play a larger role in the activation of services. Additionally, the CEO's personal preference may be the major influencing factor in the introduction of programs for community residents.
Journal of the Korean Association of Geographic Information Studies
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v.22
no.1
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pp.62-77
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2019
Open Data Cube(ODC) has been emerging and developing as the open source platform in the Committee on Earth Observation Satellites(CEOS) for the Global Earth Observation System of Systems(GEOSS) deployed by the Group on Earth Observations (GEO), ODC can be applied to the deployment of scalable and large amounts of free and open satellite images in a cloud computing environment, and ODC-based country or regional application services have been provided for public users on the high performance. This study first summarizes the status of ODC, and then presents concepts and some considering points for linking this platform with Korea Multi-Purpose Satellite (KOMPSAT) images. For the reference, the main contents of ODC with the Google Earth Engine(GEE) were compared. Application procedures of KOMPSAT satellite image to implement ODC service were explained, and an intermediate process related to data ingestion using actual data was demonstrated. As well, it suggested some practical schemes to utilize KOMPSAT satellite images for the ODC application service from the perspective of open data licensing. Policy and technical products for KOMPSAT images to ODC are expected to provide important references for GEOSS in GEO to apply new satellite images of other countries and organizations in the future.
The purpose of this study is to examine the relationship between the personal characteristics of Small and Medium-Sized Enterprises(SMEs) CEOs, on innovation behavior and corporate innovation performance, and to verify the mediating role of innovation behavior. To verify the hypothesis of this study, a questionnaire was conducted on 264 CEOs and 563 top managements of SMEs in Seoul and Gyeonggi-do. For the analysis of the investigated data, the research model and hypothesis were verified through correlation analysis, confirmatory factor analysis and SEM using SPSS and AMOS. The analysis results are as follows. First, it was found that extroversion, the personal characteristics of SMEs CEOs, had a positive (+) effect on innovation behavior, and second, openness to experience, the personal characteristics, also had a positive (+) effect on innovation behavior. Third, it was analyzed that the influence of innovation behavior on the innovation performance of a company had a positive (+) effect. Fourth, it was found that innovation behavior had full mediation effects in the relationship between extroversion and corporate innovation performance, but the case of openness to experience was not significant. Finally, the significance, implications, and limitations of the study were described, and suggestions for further study were presented.
It has been recently shown that expression of the LH receptor (LHR) in cumulus cells is related with FSH-induced meiotic resumption of mouse cumulus enclosed oocytes (CEOs). However, to date, it is still unclear whether LHR expression in cumulus cells plays a key role during FSH-induced oocyte maturation. The purpose of this study was to characterize the functional role of LHRs in cumulus cells. CEOs were isolated from eCG-primed preovulatory follicles and cultured in hypoxanthine (HX) arrested medium. LHR protein expression in cumulus cells was time-dependent increasing during the process of FSH-induced oocyte maturation. While the sense oligodeoxynucleotide (ODN) had no effect, antisense ODN inhibited FSH-induced LHR expression and meiotic resumption. Moreover, this antisense ODN against LHR could inhibit FSH-induced mitogen-activated protein kinase (MAPK) phosphorylation. This study suggested that LHR expression in cumulus cells is involved in FSH-induced oocyte meiotic resumption, which process is possibly regulated by MAPK cascade.
Previous researches have been conducted on the drivers of alliance performance up to date. Unlike existing literatures, we examine the influence of alliance management capability as direct drivers on venture's alliance performance. Based upon organizational capability theory, we proposed that coordination capability, relationship capability, learning capability are main components of alliance management capabilities. In addition, we proposed capability of CEO as forth alliance management capability in global ventures. Using 78 global ventures as research sample, this study shows that these four alliance capabilities have considerable influence on financial performance of ventures with global alliances.
This study investigated the appearance management aspects of middle-aged male CEO's based on Bourdieu's class theory. We conducted in-depth interviews with male CEOs in their 40s and 50s to understand the characteristics of appearance management in terms of economic, cultural and social capital. We found that they acquire educational capital based on their parents' economic capital and form their own cultural capital as adults. They had the characteristics of Petit Brujois, which aimed for a higher class. The characteristics of differentiation based on appearance management identified three results came from solidifying one's class position: clothing management, diversifying and upgrading appearance management, and pursuing their own ideal image. The influence of social network and cultural capital was also observed in appearance management. This study explored the characteristics of discriminatory appearance management through an in-depth study of middle-aged male CEOs as well as contributed to understanding the context of capital and appearance management by applying Bourdieu's class theory. In addition, this study provides basic data that can be referred to a design and marketing direction for the men's clothing market by providing information on male consumers with high purchasing power.
Choi, Kui Son;Lee, Sun Hee;Cho, Woo-Hyun;Kang, Hye-Young;Chae, Yoo Mi
Quality Improvement in Health Care
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v.8
no.2
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pp.146-159
/
2001
Background : To propose effective strategies for successful implementation of QI in health care institutions, by identifying facilitating factors and barriers to conducting QI programs. Methods : In order to examine empirical evidence on the success factors or barriers to QI implementation in hospitals, a literature study was performed on the basis of MEDLINE search. Among the identified literature. 13 provided reliable findings and basis comprehensive discussion on this issue and thus were selected for in-depth analysis. A mailed questionnaire survey was conducted for hospital CEOs and QI directors of hospitals with 400 beds or greater to investigate what attributes of their organizations they perceived as success factors or obstacles to QI implementation. Result : The analysis of selected literature and survey results presented that the primary factors considered to be most important as successful implementation of QI were: strong support from hospital CEOs, setting higher priority for QI activities, continuous and persistent efforts in QI activities, and active participation of clinical staffs. The barriers identified in this study were : the lack of orientation and understanding of QI concepts, low level of interest and participation of physician in QI programs, the lack of evaluation and rewarding system for QI activities. Conclusion : By identifying factors that affect facilitation of QI, the study results will be of great use for either institutions being in the early stage of evolving QI or those looking for better strategies to achieve more active and persistent QI implementation in their institutions.
This study intends to offer suggestions for improving the security and competitive power of traditional liquors by investing in the status of intellectual property rights. Merchandising and the marketing strategies of traditional liquor are also addressed. The data was collected through a questionnaire survey given to 101 CEOs of traditional liquor manufacturers. The major results of this study were as follows: The management types of traditional liquor manufacturers were classified as the company 57 (56.4%), the corporation or the union 29 (28.7%), domestic industry 10 (9.9%), and marketing community or technology center 5 (5.0%). The competitive power degree of traditional liquor products was classified as strength 30 (31.6%), usual 30 (31.6%), weakness 35 (36.8%). The elements of strong competitive power were taste, functional (wellbeing) character, and attractiveness of the brand name. On the other side, reasons for weakness in competitive power were the marketing system, price competitiveness, and advertisement. The trademark registration of the traditional liquor appeared with 53%. The reasons not to pursue a trademark registration included the complicated and unnecessary process of registration acquisition, high registration expenses, etc. The perceptions of CEOs about the consumer's brand awareness for their product were low with an average 2.97. Explanations included insufficient advertisement and public relations, unrefined trademark design, and the meaninglessness of brand names. The marketing strategy of traditional liquor manufacturers according to annual sales were as follows: Manufacturers with high sales emphasized marketing strategies that focused on functional character, traditional image, high quality in image and package materials and design, high price strategies based on quality, and various sale promotions.
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