• Journal of Korean Dental Science
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• v.14 no.1
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• pp.12-25
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• 2021

Purpose: (i) To evaluate the biologic properties of a bi-layered 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide hydrochloride-cross-linked collagen membrane (CCM) in vitro. (ii) To assess the efficacy of CCM for localized bone regeneration in vivo. Materials and Methods: Biodegradation of CCM compared to a native collagen membrane (NCM) was assessed in vitro. In vivo, twelve male New Zealand White rabbits were used. Four calvarial, circular defects (diameter 8 mm) were created in each animal. The sites were randomly allocated to i) CCM+biphasic calcium phosphate (BCP) (CCM-BCP group), ii) CCM alone (CCM), iii) BCP alone (BCP) and, iv) negative control (control). Animals were sacrificed at 2 (n=6) and 8 weeks (n=6). Outcome measures included: micro-computed tomography (μCT) analysis (total augmented volume [TAV], new bone volume) and histomorphometry (total augmented area [TAA], newly formed bone, remaining membrane thickness [RMT]). Result: CCM was more resistant to degradation than NCM. μCT analysis showed CCM-BCP (196.43±25.30 mm³) and BCP (206.23±39.13 mm³) groups had significantly (P<0.01) larger TAV than the control (149.72±12.28 mm³) after 8 weeks. Histomorphometrically, CCM-BCP group (17.75±5.97 mm²) had significantly (P<0.01) greater TAA compared to the CCM group (7.74±2.25 mm²) and the control (8.13±1.81 mm²) after 8 weeks. After 8 weeks, RMT was reduced by 67%. Conclusion: CCM can be a favorable choice of barrier membrane when performing guided bone regeneration (GBR) in localized bone defects. CCM has better resistance to degradation than the natural collagen membrane, in vitro. In vivo, CCM provides an advantageous integration of prolonged barrier function and biocompatibility for GBR.

• Journal of the Korea Institute of Information Security & Cryptology
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• v.21 no.3
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• pp.3-9
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• 2011

In this paper, we propose workload partitioning methods in parallelizing AES-CCM which is proposed as the wireless encryption and message integrity standard IEEE 802.11i. In parallelizing AES-CCM having data dependency, synchronizations among processors are required, and multi-core processors have a very large range of synchronization performance. We propose and compare the performance of various workload partitioning methods by considering both the computational characteristics of AES-CCM and the synchronization overhead.

• Food Science and Preservation
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• v.24 no.4
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• pp.536-541
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• 2017

Hyperglycemia found in diabetes mellitus causes several physiological abnormalities including the formation of advanced glycation end products (AGEs) and oxidative stress. Accumulation of AGEs and elevation of oxidative stress plays major roles in the development of diabetic complications. Adiponectin secreted from adipocytes is known to improve insulin sensitivity and blood glucose level. Curcumin (CCM), a bioactive component of turmeric, has been reported as a potent antioxidant. Present work aimed to elucidate the roles of CCM in high glucose-induced protein glycation and intracellular events in mature adipocytes. The results demonstrated that CCM inhibited the formation of fluorescent AGEs by approximated 52% at 3 weeks of bovine serum albumin (BSA) glycation with glucose. Correspondingly, CCM decreased the levels of fructosamine and ${\alpha}-dicarbonyl$ compounds during BSA glycation with glucose. These data suggested that CCM might be a new promising anti-glycation agent. Also, CCM reduced high glucose-induced oxidative stress in a dose dependent manner, whereas CCM treatment time-dependently elevated the expression of adiponectin gene in 3T3-L1 adipocytes. The findings from this study suggested the possibility of therapeutic use of CCM for the prevention of diabetic complications and obesity-related diseases.

• Journal of the Korean Society for Aeronautical & Space Sciences
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• v.45 no.3
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• pp.241-251
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• 2017

Computational fluid dynamics analysis was performed for the case 3 of the EFD-CFD workshop. Solvers were used for three commercial CFD codes(Star-CCM+, Fluent and CFX) and an open source CFD code(SU2). The grid were generated four types depending on the total cells using commercial grid generation code(Pointwise). Mach number of 0.4 and 0.8, 2 degree angle of attack and Mach number of 0.9, 1 degree angle of attack were calculated. Similar pressure coefficient curve and normal force coefficient were showed from the coarse grid to fine grid of four codes. But there is a difference in the drag coefficient. The position of the shock wave was predicted forward as the discretization order increased in calculations using Star-CCM+ and Fluent. The computation time to converge, Fluent, Star-CCM +, CFX are in order, and SU2 takes much time to converge.

• JSTS:Journal of Semiconductor Technology and Science
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• v.16 no.3
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• pp.293-299
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• 2016

Recently, as IoT (Internet of Things) becomes more important, low cost implementation of sensor nodes also becomes critical issues for two well-known standards, IEEE 802.15.4 and IEEE 802.15.6 which stands for WPAN (Wireless Personal Area Network) and WBAN (Wireless Body Area Network), respectively. This paper presents the area-optimized AES-CCM (Advanced Encryption Standard - Counter with CBC-MAC) hardware security engine which can support both IEEE 802.15.4 and IEEE 802.15.6 standards. First, for the low cost design, we propose the 8-bit AES encryption core with the S-box that consists of fully combinational logic based on composite field arithmetic. We also exploit the toggle method to reduce the complexity of design further by reusing the AES core for performing two operation mode of AES-CCM. The implementation results show that the total gate count of proposed AES-CCM security engine can be reduced by up to 42.5% compared to the conventional design.

• Journal of architectural history
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• v.8 no.1 s.18
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• pp.41-52
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• 1999

This study aims to infer the plan and location of the government office building in Chongju Castle in the Late Yi-dynasty. The conclusion is as follows: 1. The Chongju Castle Map(淸州邑城圖, late in the 18th century, hereinafter referred to CCM) provides the detail arrangement and location of Government Office Building in Chongju Castle. And the road structure and plan of the CCM is almost same with the present time. 2. As compared with CCM and a Chongju-land Registration Map(淸州面地籍原圖, 1913, CRM) to infer the location of the traditional government office building in Chongju Castle, the building locations of Gaek-Sa(客舍) Donghun(東軒)'s region in CCM are almost accordance with today's. But those of Byungyoung(兵營) Group's region are represented by a little error. So the locations of Byungyoung(兵營) Group's region rearranged, moved down to be in accordance with the approach circulation of Main Gate(閉門樓) which is shown in CRM. 3. The records, on the plan of the traditional government office building in Chongju Castle, have proved that the plan of Gaek-Sa was a width of 11 bay and a depth of 2 bay. A width of 3 bay drawn in CCM, the present plan of Donghun is a width of 7 bay and a depth of 4 bay. The main building and especially the double-storied Main Gate($4{\times}3$) of Byungyoung Group are exactly in keeping with the present road structure.

• Mass Spectrometry Letters
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• v.5 no.3
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• pp.63-69
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• 2014

In this study, we present a new isotope-coded carbamidomethylation (iCCM)-based quantitative proteomics, as a complementary strategy for conventional isotope labeling strategies, with providing the simplicity, ease of use, and robustness. In iCCM-based quantification, two proteome samples can be separately isotope-labeled by means of covalently reaction of all cysteinyl residues in proteins with iodoacetamide (IAA) and its isotope (IAA-$^{13}C_2$, $D_2$), denoted as CM and iCCM, respectively, leading to a mass shift of all cysteinyl residues to be + 4 Da. To evaluate iCCM-based isotope labeling in proteomic quantification, 6 protein standards (i.e., bovine serum albumin, serotransferrin, lysozyme, beta-lactoglobulin, beta-galactosidase, and alpha-lactalbumin) isotopically labeled with IAA and its isotope, mixed equally, and followed by proteolytic digestion. The resulting CM-/iCCM-labeled peptide mixtures were analyzed using a nLC-ESI-FT orbitrap-MS/MS. From our experimental results, we found that the efficiency of iCCM-based quantification is more superior to that of mTRAQ, as a conventional nonisobaric labeling method, in which both of a number of identified peptides from 6 protein standards and the less quantitative variations in the relative abundance ratios of heavy-/light-labeled corresponding peptide pairs. Finally, we applied the developed iCCM-based quantitative method to lung cancer serum proteome in order to evaluate the potential in biomarker discovery study.

• Asian-Australasian Journal of Animal Sciences
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• v.22 no.7
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• pp.977-983
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• 2009

The survival and effect of three new probiotic inoculants (Lactobacillus plantarum CCM 4000, L. fermentum LF2, and Enterococcus faecium CCM 4231) on the nutritive value and fermentation parameters of corn silage was studied under laboratory conditions. Whole corn plants (288.3 g/kg DM) were cut and ensiled at $21^{\circ}C$ for 105 days. The inoculants were applied at a concentration of $1.0{\times}10^{9}$ cfu/ml. Uninoculated silage was used as the control. The chopped corn was ensiled in 40 plastic jars (1 L) divided into four groups (4${\times}$10 per treatment). All corn silages had a low pH (below 3.55) and 83-85% of total silage acids comprised lactic acid after 105 days of ensiling. The probiotic inoculants in the corn silages affected corn silage characteristics in terms of significantly (p<0.05-0.001) higher pH, numerically lower crude protein content and ratio of lactic to acetic acid compared to control silage. However, the inoculants did not affect the concentration of total silage acids (acetic, propionic, lactic acids) as well as dry matter digestibility (IVDMD) of corn silages in vitro. In the corn silages with three probiotic inoculants, significantly (CCM 4231, CCM 4000) lower n-6/n-3 ratio of fatty acids was detected than in control silage. Significant decrease in the concentration of $C_{18:1}$, and significant increase in the concentration of $C_{18:2}$ and $C_{18:3}$ was mainly found in the corn silages inoculated with the strains E. faecium CCM 4231 and L. plantarum CCM 4000. At the end of ensiling, the inoculants were found at counts of less than 1.0 log10 cfu/g in corn silages.

• Proceedings of the Korean Society of Precision Engineering Conference
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• 2005.06a
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• pp.1079-1082
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• 2005

This paper deals with the algorithm development that inspects defects such as Lens Focus, Focus check, Black Defect, Dark Defect, Dim Defect, Color Defect, and Line Defect, Angle Defect, IrisAgc Defect caused by the process of 2M Class Compact Camera Module (CCM). Domestic market was majorly comprised of VGA(0.3 million pixel) market. But in the middle of year 2004, camera phone with Mega Pixel has appeared, and it is estimated that the camera phone with Mega Pixel will take up to 28% of total phone sales if it is released in the end of year 2004. Since the inspection of finished products is done manually, it is major obstacle in production increment In this paper, to solve these problems, we developed the imaging processing algorithm to inspect the defects in captured image of assembled CCM. The performances of the developed inspection system and we can recognize various types of defect of CCM modules with good accuracy and high speed

• Journal of Animal Science and Technology
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• v.53 no.5
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• pp.469-474
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• 2011

This study was conducted to investigate the effects of application of composted cattle manure (CCM) on the productivity of the whole crop rice (WCR) and Italian ryegrass (IRG) on both Sancheong and Asan area from 2005 to 2008. Application levels of CCM such as chemical fertilizer (CF), CCM 150% and CCM 200% were tested in paddy field. Amount of CCM was adjusted equal to total nitrogen value relative to its value of CF. Mean dry matter yield (DMY) of WCR and IRG increased in order; CCM 200% > CF > CCM 150% in Asan and there was no significant difference between CCM 200% and CF. In Sancheong, DMYs of WCR and IRG significantly decreased (p<0.05) in order CF > CCM 200% > CCM 150%. The plant length and number of tiller of WCR were not different among treatments, however the percentage of ripeness of WCR was higher (p<0.05) in CF compared to CCM 150% and CCM 200%. Also, there were no differences in NDF and ADF contents, however CP content was higher (p<0.05) in CF treatment compared to CCM 150% and CCM 200%. Based on the results of this experiment, IRG-WCR double cropping system with application of CCM may be effective in producing the forage resources of 18~20 tons every year with eco-friendly way.