• Title/Summary/Keyword: CB-13

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Induction of Laccase from Wood-Rotting Fungi with 2,5-Xylidine (2,5-Xylidine을 이용한 목재부후균으로부터 Laccase 효소의 유도)

  • Cho, Nam-Seok;Kim, Y.S.;Pang, M.H.;Choi, Y.J.;Nam, J.H.;Leonowicz, A.
    • Journal of the Korean Wood Science and Technology
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    • v.26 no.3
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    • pp.41-47
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    • 1998
  • Some white-rot fungi, screened at the Laboratory of Forest Products Microbiological Chemistry, Chungbuk National University were cultured and added the inducer of laccase enzyme, 2,5-xylidine. The fungi named by CB-13, CB-20, CB-99, CB-100 and CB-123 strains showed positive results in the decolorization of aromatic compounds, carminic acid and Rhemazol brilliant blue R. Concerned to the inducing effect of 2,5-xylidine on laccase activity, CB-20, CB-100 and CB-123 strains showed very high activity by addition of 2,5-xylidine, whilst CB-13, CB-99 and CB-124 strains produced relatively high laccase enzymes, regardless of inducer addition. There were no any laccase activities on CB-25, CB-64 and CB-139, even in addition of inducer. It is confirmed that some screened fungi have decolorizing ability on aromatic compounds, carminic acid and Rhemazol brilliant blue R. Also, the addition of inducer, 2,5-xylidine, has increased the activity of laccase enzyme which is secreted from some white-rot fungi.

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Analysis of Toxic-PCBs in Sediment by Isotope Dilution HRGC/HRMS (Isotope Dilution HRGC/HRMS 방법을 이용한 저니토중 Toxic-PCBs 분석)

  • Jang, Seong-Ki;Choi, Duk-Il;Park, Sun-Ku;Kim, Kyung-Sup
    • Analytical Science and Technology
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    • v.12 no.6
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    • pp.550-557
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    • 1999
  • This Analysis was conducted for 13 toxic-PCBs having TEF value among 209 PCBs isomers in sediment by isotope dilution HRGC/HRMS method. From the result, the recovery of surrogate standard was in the range of 71~99%. The concentration range for 13 toxic-PCBs in sediment was found to be 0.84~2.49 ng/g, among them the concentration levels of 2,2',3,3',4,4',5-HpCB(IUPAC No. 170) and 2,2',3,4,4',5,5'-HpCB(IUPAC No. 180) represented almost 50% of total concentrarion and that of 2,3,4,4,5-PeCB(IUPAC No. 114) showed over 10%. The TEQ concentration levelwas in the range of 0.38~2.63 pg-TEQ/g and 3,3',4,4',5-PeCB(IUPAC No. 126) concentration represented over 50% of total TEQ concentration.

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Introduction of CB Policy in Korea and Community Business Policy in Japan (지역활성화를 위한 커뮤니티 비즈니스 도입방안 -일본의 사례를 중심으로-)

  • Lee, Min-Kyu;Ryu, Sang-Il;Lee, Seok-Pyo;Kang, Hyoung-Kee
    • The Journal of the Korea Contents Association
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    • v.13 no.9
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    • pp.130-142
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    • 2013
  • The objective of the present study was to analyze the functions and requirements of CB (community business) centering on the activation of localities based on research and cases in Japan where CB is discussed actively, and to suggest the necessity and plans for introducing CB in Korea. That is, we examined the utilization of CB fittingly for the condition of Korea centering on success factors derived from research and cases in Japan, and attempted to improve the roles of the government and related organizations in introducing CB as an excellent tool for the activation of localities. Analyze the cause of success factors of CB in Japan, success factors is separated institutional dimension from operational dimension. In the institutional dimension, efficient support systems for activating CB have been established in the central government, local governments, and regions. and in the operational dimension, CB leaders are enthusiastic, members participate actively, and intermediary supporting agencies make a great contribution to CB operation.

Differences in the Quality Characteristics between Commercial Korean Native Chickens and Broilers

  • Choe, Jun-Ho;Nam, Ki-Chang;Jung, Samooel;Kim, Bin-Na;Yun, Hye-Jeong;Jo, Cheo-Run
    • Food Science of Animal Resources
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    • v.30 no.1
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    • pp.13-19
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    • 2010
  • To investigate the differences in the quality characteristics between commercial Korean native chicken (KNC) and broiler (CB), nutritive and quality parameters of the two chicken species were determined. The KNC thigh muscle had a lower content of crude fat and higher crude ash than the CB thigh. In regards to the fatty acid composition, KNC breast muscle had a higher content of arachidonic acid (C20:4) than CB. The level of inosine was higher in the CB thigh muscle than KNC but there was little difference in other nucleotide compounds. The KNC breast had higher amounts of glycine, alanine, and proline than CB, which are closely related to high quality meat flavor. The sensory acceptance was not significantly different between the breast and thigh of KNC and CB. However, KNC had higher cohesiveness, chewiness and gumminess than CB, which are indicative of a unique texture property. Based on these results, commercial KNC may have superior nutritional quality, taste, and unique texture when compared with CB. Thus, the consumer preference for KNC may be partially explained by these distinctive quality characteristics.

D-band Stacked Amplifiers based on SiGe BiCMOS Technology

  • Yun, Jongwon;Kim, Hyunchul;Song, Kiryong;Rieh, Jae-Sung
    • JSTS:Journal of Semiconductor Technology and Science
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    • v.15 no.2
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    • pp.276-279
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    • 2015
  • This paper presents two 3-stage D-band stacked amplifiers developed in a $0.13-{\mu}m$ SiGe BiCMOS technology, employed to compare the conventional cascode topology and the common-base (CB)/CB stacked topology. AMP1 employs two cascode stages followed by a CB/CB stacked stage, while AMP2 is composed of three CB/CB stacked stages. AMP1 showed a 17.1 dB peak gain at 143.8 GHz and a saturation output power of -4.2 dBm, while AMP2 showed a 20.4 dB peak gain at 150.6 GHz and a saturation output power of -1.3 dBm. The respective power dissipation was 42.9 mW and 59.4 mW for the two amplifiers. The results show that CB/CB stacked topology is favored over cascode topology in terms of gain near 140 GHz.

Comparison study between recovered carbon black and commercial carbon black filled epoxy conductive materials

  • Huai M. Ooi;Pei L. Teh;Cheow K. Yeoh;Wee C. Wong;Chong H. Yew;Xue Y. Lim;Kai K. Yeoh;Nor A. Abdul Rahim;Chun H. Voon
    • Advances in materials Research
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    • v.13 no.3
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    • pp.221-232
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    • 2024
  • Waste tire management and recycling have grown to be significant issues because they bring up a global environmental concern. Thus, turning recycled waste tires into useful products may help tackle the environmental issue. This research aims to study and compare the effect of recycled carbon black (rCB) and commercial carbon black (CB) at certain 15 vol. % of filler loading on the mechanical, thermal, morphology and electrical properties of epoxy/CB composites. For this project, epoxy resin, diethyltoluenediamine (DETDA), recovered carbon black (rCB) and commercial carbon black (CB) graded N330, N550, N660 and N774 were mixed and compared accordingly to the formulation determined. The CB content was dispersed in the epoxy matrix using the mechanical mixing technique. The distribution and dispersion of CB in the epoxy matrix affect the characteristics of the conductive composites. rCB content at 15 vol% was selected at fixed content for comparison purposes due to the optimum value in electrical conductivity results. The flexural strength results followed the sequence of rCB>N774>N660>N550>N330. As for electrical conductivity results, epoxy/N330 exhibited the highest conductivity value, while the others achieved a magnitude of X10-3 due to the highest external surface area of N330. In terms of thermal stability, epoxy/N330 and epoxy/N774 were slightly more stable than epoxy/rCB.

Efficacy of Exemestane After Nonsteroidal Aromatase inhibitor Use in Metastatic Breast Cancer Patients

  • Kim, Sun-Hye;Park, In-Hae;Lee, Hye-Won;Lee, Keun-Seok;Nam, Byung-Ho;Ro, Jung-Sil
    • Asian Pacific Journal of Cancer Prevention
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    • v.13 no.3
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    • pp.979-983
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    • 2012
  • Background : Previous studies have suggested a lack of complete cross-resistance between steroidal (exemestane) and non-steroidal aromatase inhibitors (nSAI). Methods : Eighty-eight metastatic breast cancer (MBC) patients who received 25 mg of exemestane orally once a day at the National Cancer Center, Korea, between 2003 and 2009, were reviewed retrospectively. All patients had received nSAI for metastatic disease prior to exemestane therapy. Results : The median age was 52 years (range, 33-79), and 13 (14.8%) patients were premenopausal who concomitantly received GnRH agonist. Exemestane was given as a second- (80.7%) or third-line (19.3%) hormone therapy. The clinical benefit (CB) rate (complete response + partial response + stable disease ${\geq}$ 24 weeks) was 30.7%, with a median CB duration of 10.0 months (range, 6.3-78.7). The median progression-free survival (PFS) was 3.0 months (95% confidence interval [CI], 1.99-4.01) and the overall survival (OS) 21.5 months (95% CI, 17.96-25.04), with a median followup of 50.3 months. Patients who achieved CB had longer OS than those patients who did not (29.6 vs 17.9 months; P=0.002). On univariate analysis of predictive factors, patients who had achieved CB from previous nSAI tended to show lower CB rate (24.6% vs 44.4%, respectively; P=0.063) and shorter PFS (2.8 vs 4.8 months, respectively; p=0.233) than patients who had not. Achieving CB from previous nSAI became independent predictive factor for CBR to exemestane on multivariable analysis (Odds ratio = 2.852, P = 0.040). Conclusions : Exemestane after nSAI failure was effective in prolonging CB duration. The drug's efficacy seemed to be inferior in patients who had benefit from previous nSAI use.

Effects of Survivability of Frozen Porcine Embryos by Different Concentrations and Exposed Times of Cytochalasin-B before Vitrification (돼지 배아의 유리화 동결 시 Cytochalasin B의 농도와 처리 시간에 의한 효과)

  • 안미현;김인덕;석호봉
    • Journal of Embryo Transfer
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    • v.19 no.1
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    • pp.35-42
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    • 2004
  • The purpose of this study was to evaluate the effects of Cytochalasin B treatment on the survivability The different concentration and exposed times of CB of porcine embryos frozen by vitrification were observed. The results were summarized as follows ; 1. The survivability rates of the porcine embryos treated CB(60.5%) were significantly higher than non-treated(32.8%)(p<0.1). However the recovered with normal morphology rates(84.2%) were no significantly different than non-treated(81.9%). 2. We observed by different concentration of CB treatment, the group of CB treated with 7.5 $\mu\textrm{g}$/$m\ell$ were significantly showed a higher of normal morphology(44/45; 98%) and viability rate(33/45;73%) than other groups(morphology: 65∼70%, viability: 15∼74%)(p<0.05). While the control was lower as 70% of morphology and 38% of viability. 3. We examined exposed time of in-vitro CB treated embryos, the group of more than 20 minutes exposed were significantly were observed a higher rates of normal morphology and viability(p<0.05). And the group of 13 minutes, 14,000 rpm centrifuged(64%) were significantly higher than non-centrifuged(36%). Survivability of porcine embryos were improved in CB treated group. It suggested that 7.5 $\mu\textrm{g}$/$m\ell$ concentration of CB treatment, 20 minutes exposed times and 13 minutes, 14000 rpm centrifuged prior to vitrification improve normal morphology and survivability rates.

Abuse Potential of Synthetic Cannabinoids: AM-1248, CB-13, and PB-22

  • Hur, Kwang-Hyun;Ma, Shi-Xun;Lee, Bo-Ram;Ko, Yong-Hyun;Seo, Jee-Yeon;Ryu, Hye Won;Kim, Hye Jin;Yoon, Seolmin;Lee, Yong-Sup;Lee, Seok-Yong;Jang, Choon-Gon
    • Biomolecules & Therapeutics
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    • v.29 no.4
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    • pp.384-391
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    • 2021
  • Currently, the expanding recreational use of synthetic cannabinoids (SCBs) threatens public health. SCBs produce psychoactive effects similar to those of tetrahydrocannabinol, the main component of cannabis, and additionally induce unexpected pharmacological side effects. SCBs are falsely advertised as legal and safe, but in reality, SCB abuse has been reported to cause acute intoxication and addictive disorders. However, because of the lack of scientific evidence to elucidate their dangerous pharmacological effects, SCBs are weakly regulated and continue to circulate in illegal drug markets. In the present study, the intravenous self-administration (IVSA) paradigm was used to evaluate the abuse potential of three SCBs (AM-1248, CB-13, and PB-22) in rats. All three SCBs maintained IVSA with a large number of infusions and active lever presses, demonstrating their reinforcing effects. The increase of active lever presses was particularly significant during the early IVSA sessions, indicating the reinforcement-enhancing effects of the SCBs (AM-1248 and CB-13). The number of inactive lever presses was significantly higher in the SCB groups (AM-1248 and CB-13) than that in the vehicle group, indicating their impulsive effects. In summary, these results demonstrated that SCBs have distinct pharmacological properties and abuse potential.

Determination of Total Content of Phenolic Compounds in Chinese Matrimony Vine's Accessions (국내외 수집종 구기자 잎과 줄기의 페놀화합물 함량)

  • Cho, Jin-Woong;An, Tae-Hwan;Lee, Suk-Young;Park, Kee Woong
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.57 no.4
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    • pp.409-417
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    • 2012
  • This study was conducted to determine the variation of phenolic compounds in the leaf and stem of 131 accessions of Lycium chinesis Miller. The levels of total phenolic compounds in the leaf of L. chinesis ranged between 8.8 to $14.9mg\;g^{-1}$ and among them 60% of the accessions belong between 11.6 and $13.5mg\;g^{-1}$ for the content of phenolic compounds in the leaf. The accession CB03286-89 contained the highest total phenolic compounds among the accessions tested, which was 1.7-fold higher than that of the lowest content accession CBP03310-250. In the stem, the total phenolic compound of 131 accessions of L. chinesis ranged from 6.8 to $12.4mg\;g^{-1}$, showing slightly lower level than that in the leaf. The content of (+)catechin was highest in the leaf and stem of accession CB03286-89 and Japan No.1, respectively. Myricetin was detected in the leaf of seven accessions (i.e. Geumsan jaerae, Japan No.1, China collection No.1, CL32-13, CB04329-13, China collection No.12 and CB03286-89) and in the stem of five accessions (i.e., Japan No.1, China collection No.1, China collection No.12, CB03286-89 and 99797). Accessions had a great influence on the content of phenolic compounds. So, accessions-specific phenolic compound profiles might be helpful for commercial use or production of phenolic compounds in L. chinesis.