• Title/Summary/Keyword: CB-13

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2,5-Xylidine을 이용한 목재부후균으로부터 Laccase 효소의 유도 (Induction of Laccase from Wood-Rotting Fungi with 2,5-Xylidine)

  • 조남석;김영신;방명혁;최윤정;남장현;안드레 레오노비취
    • Journal of the Korean Wood Science and Technology
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    • 제26권3호
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    • pp.41-47
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    • 1998
  • Some white-rot fungi, screened at the Laboratory of Forest Products Microbiological Chemistry, Chungbuk National University were cultured and added the inducer of laccase enzyme, 2,5-xylidine. The fungi named by CB-13, CB-20, CB-99, CB-100 and CB-123 strains showed positive results in the decolorization of aromatic compounds, carminic acid and Rhemazol brilliant blue R. Concerned to the inducing effect of 2,5-xylidine on laccase activity, CB-20, CB-100 and CB-123 strains showed very high activity by addition of 2,5-xylidine, whilst CB-13, CB-99 and CB-124 strains produced relatively high laccase enzymes, regardless of inducer addition. There were no any laccase activities on CB-25, CB-64 and CB-139, even in addition of inducer. It is confirmed that some screened fungi have decolorizing ability on aromatic compounds, carminic acid and Rhemazol brilliant blue R. Also, the addition of inducer, 2,5-xylidine, has increased the activity of laccase enzyme which is secreted from some white-rot fungi.

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Isotope Dilution HRGC/HRMS 방법을 이용한 저니토중 Toxic-PCBs 분석 (Analysis of Toxic-PCBs in Sediment by Isotope Dilution HRGC/HRMS)

  • 장성기;최덕일;박선구;김경섭
    • 분석과학
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    • 제12권6호
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    • pp.550-557
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    • 1999
  • 본 연구에서는 209종의 PCBs 이성체중 독성등가계수(Toxic Equivalance Factor, TEF)가 제시된 13종의 toxic-PCBs에 대하여 Isotope dilution HRCC/HRMS 방법으로 저니토중의 toxic-PCBs를 분석하였다. 분석결과 surrogate 표준물질의 회수율은 71~99%로 양호하였다. 13종의 toxic-PCBs 농도는 0.84~2.49 ng/g 범위이었으며, 이중 2,2',3,3',4,4',5-HpCB(IUPAC No. 170) 및 2,2',3,4,4',5,5'-HpCB(IUPAC No. 180) 농도가 전체 농도의 50% 정도를 나타내었으며, 2,3,4,4,5-PeCB(IUPAC No. 114)도 10% 정도를 나타내었다. 독성등가계수로 환산한 농도는 0.38~2.63 pg-TEQ/g 범위이었으며, 3,3',4,4',5-PeCB(lUPAC No. 126)가 전체의 50%를 나타내었다.

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지역활성화를 위한 커뮤니티 비즈니스 도입방안 -일본의 사례를 중심으로- (Introduction of CB Policy in Korea and Community Business Policy in Japan)

  • 이민규;류상일;이석표;강형기
    • 한국콘텐츠학회논문지
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    • 제13권9호
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    • pp.130-142
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    • 2013
  • 이 연구는 커뮤니티 재생의 수단으로서 CB의 활용방안을 연구한 것이다. 즉, CB를 통해 지역 커뮤니티 조직은 활성화시키고, CB조직이 전개하는 사업의 지속성을 기반으로 커뮤니티 조직구성원에 활력을 제공한다는 측면에서 CB는 중요한 시사점을 제공한다. 더욱이 민간영역 중에서 영리추구를 최고의 목표로 설정하고 있는 기업과 느슨한 조직 동력을 갖는 자원봉사조직 등의 NGO NPO 조직 사이의 장점을 조합한 CB는 한국의 지역 커뮤니티 재생에 새로운 활력을 불러일으키는 수단이 될 것이다. 따라서 이 연구는 CB에 대한 활발한 논의가 진행되고 있는 일본의 연구와 사례를 검토 분석함으로써 지역 활성화를 중심으로 한 CB의 성공요인을 도출해내어 한국에의 도입방안을 도출하고 있다. 분석결과 일본에서 CB가 지니는 기능 내지 역할로는 첫째, CB의 가장 중요한 역할로써 지역과제의 공유기능을 생각할 수 있고, 둘째, 지역의 고용창출 기능을 들 수 있으며, 셋째, CB의 제3의 역할로써 지역에 필요한 서비스를 보완하는 기능을 생각할 수 있다.넷째, 일본의 경우 복지서비스, 환경보호, 일거리 창출 등 종래의 행정이 독점해왔던 분야에서 CB사업을 수행하는 단체의 활약이 현저하다. 즉, CB가 행정을 대체하는 기능을 한다는 점은 어느 정도 설명력이 있는 것이다. 다섯째, CB의 다섯 번째 역할로써 시장실패를 보완하는 기능을 생각해 볼 수 있으며, 마지막으로 CB의 가장 중요한 역할 중 하나로 인식될 수 있는 기능이 커뮤니티의 재생일 것이다.

Differences in the Quality Characteristics between Commercial Korean Native Chickens and Broilers

  • Choe, Jun-Ho;Nam, Ki-Chang;Jung, Samooel;Kim, Bin-Na;Yun, Hye-Jeong;Jo, Cheo-Run
    • 한국축산식품학회지
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    • 제30권1호
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    • pp.13-19
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    • 2010
  • To investigate the differences in the quality characteristics between commercial Korean native chicken (KNC) and broiler (CB), nutritive and quality parameters of the two chicken species were determined. The KNC thigh muscle had a lower content of crude fat and higher crude ash than the CB thigh. In regards to the fatty acid composition, KNC breast muscle had a higher content of arachidonic acid (C20:4) than CB. The level of inosine was higher in the CB thigh muscle than KNC but there was little difference in other nucleotide compounds. The KNC breast had higher amounts of glycine, alanine, and proline than CB, which are closely related to high quality meat flavor. The sensory acceptance was not significantly different between the breast and thigh of KNC and CB. However, KNC had higher cohesiveness, chewiness and gumminess than CB, which are indicative of a unique texture property. Based on these results, commercial KNC may have superior nutritional quality, taste, and unique texture when compared with CB. Thus, the consumer preference for KNC may be partially explained by these distinctive quality characteristics.

D-band Stacked Amplifiers based on SiGe BiCMOS Technology

  • Yun, Jongwon;Kim, Hyunchul;Song, Kiryong;Rieh, Jae-Sung
    • JSTS:Journal of Semiconductor Technology and Science
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    • 제15권2호
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    • pp.276-279
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    • 2015
  • This paper presents two 3-stage D-band stacked amplifiers developed in a $0.13-{\mu}m$ SiGe BiCMOS technology, employed to compare the conventional cascode topology and the common-base (CB)/CB stacked topology. AMP1 employs two cascode stages followed by a CB/CB stacked stage, while AMP2 is composed of three CB/CB stacked stages. AMP1 showed a 17.1 dB peak gain at 143.8 GHz and a saturation output power of -4.2 dBm, while AMP2 showed a 20.4 dB peak gain at 150.6 GHz and a saturation output power of -1.3 dBm. The respective power dissipation was 42.9 mW and 59.4 mW for the two amplifiers. The results show that CB/CB stacked topology is favored over cascode topology in terms of gain near 140 GHz.

Comparison study between recovered carbon black and commercial carbon black filled epoxy conductive materials

  • Huai M. Ooi;Pei L. Teh;Cheow K. Yeoh;Wee C. Wong;Chong H. Yew;Xue Y. Lim;Kai K. Yeoh;Nor A. Abdul Rahim;Chun H. Voon
    • Advances in materials Research
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    • 제13권3호
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    • pp.221-232
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    • 2024
  • Waste tire management and recycling have grown to be significant issues because they bring up a global environmental concern. Thus, turning recycled waste tires into useful products may help tackle the environmental issue. This research aims to study and compare the effect of recycled carbon black (rCB) and commercial carbon black (CB) at certain 15 vol. % of filler loading on the mechanical, thermal, morphology and electrical properties of epoxy/CB composites. For this project, epoxy resin, diethyltoluenediamine (DETDA), recovered carbon black (rCB) and commercial carbon black (CB) graded N330, N550, N660 and N774 were mixed and compared accordingly to the formulation determined. The CB content was dispersed in the epoxy matrix using the mechanical mixing technique. The distribution and dispersion of CB in the epoxy matrix affect the characteristics of the conductive composites. rCB content at 15 vol% was selected at fixed content for comparison purposes due to the optimum value in electrical conductivity results. The flexural strength results followed the sequence of rCB>N774>N660>N550>N330. As for electrical conductivity results, epoxy/N330 exhibited the highest conductivity value, while the others achieved a magnitude of X10-3 due to the highest external surface area of N330. In terms of thermal stability, epoxy/N330 and epoxy/N774 were slightly more stable than epoxy/rCB.

Efficacy of Exemestane After Nonsteroidal Aromatase inhibitor Use in Metastatic Breast Cancer Patients

  • Kim, Sun-Hye;Park, In-Hae;Lee, Hye-Won;Lee, Keun-Seok;Nam, Byung-Ho;Ro, Jung-Sil
    • Asian Pacific Journal of Cancer Prevention
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    • 제13권3호
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    • pp.979-983
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    • 2012
  • Background : Previous studies have suggested a lack of complete cross-resistance between steroidal (exemestane) and non-steroidal aromatase inhibitors (nSAI). Methods : Eighty-eight metastatic breast cancer (MBC) patients who received 25 mg of exemestane orally once a day at the National Cancer Center, Korea, between 2003 and 2009, were reviewed retrospectively. All patients had received nSAI for metastatic disease prior to exemestane therapy. Results : The median age was 52 years (range, 33-79), and 13 (14.8%) patients were premenopausal who concomitantly received GnRH agonist. Exemestane was given as a second- (80.7%) or third-line (19.3%) hormone therapy. The clinical benefit (CB) rate (complete response + partial response + stable disease ${\geq}$ 24 weeks) was 30.7%, with a median CB duration of 10.0 months (range, 6.3-78.7). The median progression-free survival (PFS) was 3.0 months (95% confidence interval [CI], 1.99-4.01) and the overall survival (OS) 21.5 months (95% CI, 17.96-25.04), with a median followup of 50.3 months. Patients who achieved CB had longer OS than those patients who did not (29.6 vs 17.9 months; P=0.002). On univariate analysis of predictive factors, patients who had achieved CB from previous nSAI tended to show lower CB rate (24.6% vs 44.4%, respectively; P=0.063) and shorter PFS (2.8 vs 4.8 months, respectively; p=0.233) than patients who had not. Achieving CB from previous nSAI became independent predictive factor for CBR to exemestane on multivariable analysis (Odds ratio = 2.852, P = 0.040). Conclusions : Exemestane after nSAI failure was effective in prolonging CB duration. The drug's efficacy seemed to be inferior in patients who had benefit from previous nSAI use.

돼지 배아의 유리화 동결 시 Cytochalasin B의 농도와 처리 시간에 의한 효과 (Effects of Survivability of Frozen Porcine Embryos by Different Concentrations and Exposed Times of Cytochalasin-B before Vitrification)

  • 안미현;김인덕;석호봉
    • 한국수정란이식학회지
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    • 제19권1호
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    • pp.35-42
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    • 2004
  • 본 연구는 돼지 배아의 유리화 동결 시 CB 처리군과 CB 비처리군의 영향을 비교하였다. CB의 농도별, 처리 시간별로 처리한 뒤 유리화 동결 융해 후 정상적인 형태 회수율과 생존률을 각각 조사하였다. 1. CB를 전 처리한 군과 비처리군의 정상적인 형태율이 각각 84.2%, 81.9%로 유의한 차이가 없었으나, 융해 후 72시간 째 생존률의 결과에서는 각각 60.5%, 32.8%로 유의성(p<0.1)이 검증되었다. 2. CB 농도별 생존률에 미치는 영향은 7.5 $\mu\textrm{g}$/$m\ell$의 처리군이 다른 처리군에 비하여 유의적으로 높았다(p<0.05). 정상 형태율 95%와 융해 후 생존률 73%로서 다른 농도에 비하여 65∼76%, 15∼57%보다 각각 높았다. 3. 7.5 $\mu\textrm{g}$/$m\ell$ 농도의 CB 전처리의 처리 시간에 따른 영향은 20분 처리하였을 때 정상적인 형태율은 81%로 다른 처리군(25∼69%)보다 높았고, 24시간 째 생존률의 결과로도 64%, 6∼56%로 유의적인 차이는 나타나지 않았다. 또한 원심 처리군과 비처리군에서도 CB를 20분으로 처리하였을 때 가장 좋은 결과를 나타내었으며, 원심 비처리군보다는 원심 처리군이 좀 더 높은 결과를 보여 주었다.

Abuse Potential of Synthetic Cannabinoids: AM-1248, CB-13, and PB-22

  • Hur, Kwang-Hyun;Ma, Shi-Xun;Lee, Bo-Ram;Ko, Yong-Hyun;Seo, Jee-Yeon;Ryu, Hye Won;Kim, Hye Jin;Yoon, Seolmin;Lee, Yong-Sup;Lee, Seok-Yong;Jang, Choon-Gon
    • Biomolecules & Therapeutics
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    • 제29권4호
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    • pp.384-391
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    • 2021
  • Currently, the expanding recreational use of synthetic cannabinoids (SCBs) threatens public health. SCBs produce psychoactive effects similar to those of tetrahydrocannabinol, the main component of cannabis, and additionally induce unexpected pharmacological side effects. SCBs are falsely advertised as legal and safe, but in reality, SCB abuse has been reported to cause acute intoxication and addictive disorders. However, because of the lack of scientific evidence to elucidate their dangerous pharmacological effects, SCBs are weakly regulated and continue to circulate in illegal drug markets. In the present study, the intravenous self-administration (IVSA) paradigm was used to evaluate the abuse potential of three SCBs (AM-1248, CB-13, and PB-22) in rats. All three SCBs maintained IVSA with a large number of infusions and active lever presses, demonstrating their reinforcing effects. The increase of active lever presses was particularly significant during the early IVSA sessions, indicating the reinforcement-enhancing effects of the SCBs (AM-1248 and CB-13). The number of inactive lever presses was significantly higher in the SCB groups (AM-1248 and CB-13) than that in the vehicle group, indicating their impulsive effects. In summary, these results demonstrated that SCBs have distinct pharmacological properties and abuse potential.

국내외 수집종 구기자 잎과 줄기의 페놀화합물 함량 (Determination of Total Content of Phenolic Compounds in Chinese Matrimony Vine's Accessions)

  • 조진웅;안태환;이석영;박기웅
    • 한국작물학회지
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    • 제57권4호
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    • pp.409-417
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    • 2012
  • 본 연구는 우리나라에서 보존하고 있는 구기자(Lycium chinesis Miller) 유전자원 131점의 잎과 줄기를 에탄올로 추출한 후 페놀화합물의 함량을 측정하여 비교 분석하기 위하여 수행되었다. 구기자 잎의 페놀 함량은 $8.8{\sim}14.9mg\;g^{-1}$을 보였으며 $11.6{\sim}13.5mg\;g^{-1}$ 사이에는 약 60%의 유전자원이 분포되어 있었다. CB03286-89 유전자원은 총 페놀함량이 $14.9{\pm}0.3mg\;g^{-1}$으로 가장 높은 반면 CBP03310-250은 $8.8{\pm}0.2mg\;g^{-1}$으로 가장 낮은 함량을 보였다. 줄기에 대한 총 페놀함량은 $6.8{\sim}12.4mg\;g^{-1}$의 함량 범위를 보이고 있으며 잎보다는 상대적으로 다소 낮은 것으로 나타났다. 구기자 잎의 페놀화합물 중 33가지 물질을 정량 분석한 결과 China collection No.1에서 가장 높게 나타났으며 99797 수집종에서 가장 낮게 나타났다. (+)catechin 함량은 CB03286-89에서 가장 많았다. Myricetin은 Geumsan jaerae, Japan No.1, China collection No.1, CL32-13, CB04329-13, China collection No.12 그리고 CB03286-89 등에서 분석되었지만 나머지 구기자 유전자원의 잎에서는 검출되지 않았다. 줄기에 대한 페놀화합물은 잎에 비하여 상대적으로 함량이 적었으며 99797 수집종이 가장 많은 함량을 보였으나 CB04329-13에서는 가장 적은 함량을 보였다. (+)catechin 함량은 Japan No.1이 $231.0{\pm}0.5{\mu}g\;g^{-1}$으로 가장 높았으며, myricetin은 Japan No.1, China collection No.1, China collection No.12, CB03286-89 및 99797에서 분석되었지만 나머지 구기자 유전자원의 줄기에서는 검출되지 않았다.