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Botulinum Toxin A Treatment for Cervical Dystonia Resulting in Endoscopic Thyroidectomy: A Case Report (내시경 갑상샘 절제술 후 발생한 경부 근긴장이상증의 보툴리늄 A 독소를 이용한 치료: 증례보고)

  • Oh, Hwa-Young;Choi, Hwan-Jun;Nam, Doo-Hyun;Kim, Jun-Hyuk;Lee, Young-Man
    • Archives of Plastic Surgery
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    • v.38 no.2
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    • pp.207-211
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    • 2011
  • Purpose: Surgery for thyroid gland requires skin incisions that can result in postsurgical neck scar. To overcome this, many surgeons performed a endoscopic thyroidectomy. But, this approach had a some problems. One of postoperative problems, iatrogenic cervical dystonia (CD) may occur. At common, CD is defined as a syndrome characterized by prolonged muscle contraction causing twisting, repetitive movements or abnormal posture. Botulinum toxin A (BTA, Botox$^{(R)}$, Allergan, Irvine, CA, USA) is well known treatment agent in the treatment of CD. So, the authors applied BTA injection in rare case with iatrogenic CD resulting in endoscopic thyroidectomy. Methods: A 43-year-old female had endoscopic subtotal thyroidectomy operation 3 years ago. She had symptoms such as progressive cervical pain, abnormal neck posture, depression, and sleep difficulty. About 1 year later, the patient who had previous myomectomy of the clavicular head of sternocleidomastoid muscle, however, symptoms were not improved. And then the patient received BTA therapy in our department. The 2 units per 0.1 mL solution was administered in a 1 mL tuberculin syringe. Results: The dose of BTA used in the patient was 36 units for vertical platysmal bands, superficially, and 10 units for ipsilateral sternocleidomastoid muscle, intramuscularly. After 2 weeks, additional the dose of BTA used in the patient was 5 points for remained scar bands, superficially. Complications related to injection such as significant swallowing difficulties, neck muscle weakness, or sensory change were not observed. In 9 months follow-up, the patient maintained a good result from the method of BTA injection alone. Conclusion: The basic concept is selective denervation for the hyperactive individual muscles and scar bands. We conclude that BTA is an effective and safe treatment for CD despite the iatrogenic and complex presentation of this complication.

Physiological and Ecological Characteristics of Indigenous Soybean Rhizobia Distributed in Korea -I. Relationship between Distribution of the Indigenous Rhizobia and Physico-Chemical Properties (우리나라 토착대두근류균(土着大豆根瘤菌)의 분포상태(分布狀態)와 생리(生理) 및 생태학적(生態學的) 특성(特性) -제(第) 1 보(報). 토착근류균(土着根瘤菌)의 분포상태(分布狀態)와 토양특성(土壤特性)과의 상호관계(相互關係))

  • Ryu, Jin-Chang;Lee, Seong-Jae;Suh, Jang-Sun;Cho, Moo-Je
    • Korean Journal of Soil Science and Fertilizer
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    • v.19 no.1
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    • pp.38-49
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    • 1986
  • In order to improve effectiveness of rhizobia-legume symbiotic nitrogen fixation, ecological and physiological characteristics of indigenous rhizobia distributed in Korea soil, that is, the effects of soybean cultivation, physico-chemical properties and climate on the population of indigenous rhizobia and other soil microbes were investigated. The results were summarized as follows: The population of indigenous rhizobia were ranged from $5.1{\times}10^4$ cells to $196.8{\times}10^4$ cells per gram of soil in soybean cultivated soils but from $1.6{\times}10^4$ cells to $78.6{\times}10^4$ cells per gram of soil in soybean un-cultivated soils sampled from 9 different agro-climate zone. The highest population was observed in a soybean cultivated loamy soil from southern part of Korea. The content of available phosphate, exchangeable Ca, Mg, Cu, and B in soil were positively correlated but active Fe, exchangeable Al, Na, and $SO_4$ were inversely correlated to the population of indigenous rhizobia. The inverse relationship was observed between the number of indigenous rhizobia and actinomycetes.

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Tiger Beetles(Carabidae, Cicindelinae) of Korea (한국산 길앞잡이 (딱정벌레목, 딱정벌레과))

  • Kim, Tae-Heung;Paik, Jong-Cheol;Jeong, Kyu-Hwan
    • The Korean Journal of Soil Zoology
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    • v.10 no.1_2
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    • pp.1-15
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    • 2005
  • Tiger Beetles(Carabidae, Cicindelinae) were collected in the Province of Chollabukdo including some nearby islands from April 1997 to October 2002. The specimens of ca. 500 deposited in Sunchon National University, Chonbuk National University, the Jeju Folklore and Natural History Museum, and elsewhere were also examined. As a result, Korean Cicindelinae of 18 species from 10 subgenera is reported herein. Of these, Cicindela (Cylindera) obliquefasciata Adams, 1817 and Cicindeia (Cephalota) chiloleuca Fisher, 1820 are recorded newly in the Korean Peninsula. However, the distribution of C. japana is very doubtful in South Korea. This study also includes a key to the species, discussions on the habitats, distributions, and some ecological characteristics of Korean Cicindelinae.

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Non-Adrenergic Non-Cholinergic Responses of Gu mea- Pig Tracheal Smooth Muscle (기니피그 기도 평활근의 비아드레날린성 비꼴린성 반응에 관한 연구)

  • Jo, Eun-Yong;Choe, Hyeong-Ho;Jeon, Je-Yeol
    • Journal of Chest Surgery
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    • v.29 no.5
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    • pp.487-494
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    • 1996
  • The neurogenic responses of tracheal smooth muscles to electrical field stimulation (EFS) is biphasic, consisting firstly of cholinergic contraction followed by a slow and sustained relaxation. It is well known that a sustained relaxation involves the inhibitory non-adrenergic non-cholinergic systems. This study was done to Investigate the relaxing agents and their action mechanisms by use of an organ bath with plati- ilum . The tracheal smooth muscle relaxation due to EFS was suppressed by L-NAME, the WO (Nitric Oxide) synthase inhibitor, and these effects were reversed by L-arginine, the precursor of NO. Also, L-WAME (HG-nitro-L-arginine methyl ester) increased the basal tension. Nitroprusside, the NO-donor, suppressed the tracheal basal tension greatly. Methylene blue, the inhibitor of guanylate cyclase, decreased EFS-induced relaxations and increa ed basal tension. Forskolin and isoprenaline, which are activators of adenylate cyclase, suppressed tracheal basal tension in the same way as nitroprusside. TEA (tetraethylammonium), the non-specific K'channel blocker, and apamin, the Ca"-activated K'channel blocker, increased tracheal basal tension and EFS-induced relaxations. Our results indicate that Pr3 Is released upon stimulation of the NANC (Won Adrenergic Won Cholinergic) nerves in guinea-pig tracheal smooth muscle and that the release of NO related with the K+ channel, as well as the release of other inhibitory agents< e. g.)VIP (Vasoactive Intestinal Polypeptide), PHI (Peptide Histidine Isoleusine) > mediated via CAMP (cyclic Adenosine Monophosphate) may be Involved In sustained relaxation.

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Characteristics of Growth and Germination of Salicornia herbacea L. for the Soil salinity and Manure Condition (토양염분.시비 조건에 따른 퉁퉁마디 생장 및 발아 특성)

  • Jo, Yeong-Cheol;Lee, Kyeong-Sik;Chon, Song-Mi;Byun, Do-Seung
    • Korean Journal of Medicinal Crop Science
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    • v.10 no.2
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    • pp.100-108
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    • 2002
  • This experiment was carried out to investigate the cultivation condition of soil salinity, manure and to find out the cultivation capability of Salicornia herbacea. The optimal growth condition of soil salinity was between 1% and 4%. The growth of groups for fertilization was significantly better than control group. Salicornia herbacea grew very up from 7 kg/l0a to 9 kg/l0a for N, 12 kg/l0a for P and the K-fertilizer group was better than control group but there was not significantly different among the conditions of K-concentration. The germination was good from $0{\textperthousand}\;to\;5{\textperthousand}$ for salinity, from $20^{\circ}C\;to\;30^{\circ}C$ for temperature. On the experiment cultivation, the production by hill seeding was $5.40{\sim}5.90 kg/m^2$ and was significantly higher than the yield by broadcast sowing which was $4.01{\sim}4.20 kg/m^2$. The production by hill seeding was 2.7 times than natural production and the production by broadcast sowing 1.9 times.

Effects of Hairy Vetch and Animal Slurry on Growth and Yield of Astragalus membranaceus Bunge (헤어리베치 녹비 및 액상분뇨 시용이 황기 생육과 수량에 미치는 영향)

  • Ryoo, Jong-Won
    • Korean Journal of Medicinal Crop Science
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    • v.11 no.2
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    • pp.83-88
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    • 2003
  • This experiment was carried out to investigate the effect of the mulching of hairy vetch and pig manure on the growth, yield and crude protein contents of the mulching of hairy vetch and application of animal slurry were treated and investigated in $2000{\sim}2002$. At the first year of cultivation, there were no differences among the treatments in plant height, but second year the growth of plants increased and continued over long times as the hairy vetch mulched and fertilized. The length and diameter of plant root were increased in the plot of hairy vetch mulching and the application of animal slurry. At first year of cultivation, no clear difference was found for among the treatments on dry weight and dry matter ratio in roots. At second year of cultivation, they were increased at in the plot of mulching and fertilizer treatment. The appearances of weeds in the field on Astragalus membranaces were much lower on the plots of live-mulching of hairy vetch than those on the control. The yield of root was 255kg highest in the plot of mulching and animal slurry application of 2-year-old roots. The root yield of Astragalus membranaces was increased about $8{\sim}10%$ compared to that with control, due to supply of nutrients. During the cultivation times, organic matters and N contents in soil increased by the mulching of hairy vetch and the application of animal slurry. The concentration of K, Ca concentration in soil showed a tendency to increase.

Applied-mineralogical Characterization for the Quick-lime Manufactured from Fine-grained Domestic Limestones (국내산 세립질 석회석으로부터 제조된 생석회에 대한 응용광물학적 특성 평가)

  • Noh, Jin-Hwan;Lee, Hyun-Chul
    • Journal of the Mineralogical Society of Korea
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    • v.22 no.3
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    • pp.261-277
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    • 2009
  • This study is aimed to emphasize the significance of ore selection in lime manufacturing through the evaluation of applied-mineralogical impact factors of crude ores controlling calcination characteristics for some domestic limestones used currently for lime manufacturing. To do this work, systematic characterization and determination were carried out for the limestone ores and their calcination products in a fixed calcining condition (target temperature: $1000^{\circ}C$, retention time: 30 minutes, 2, 4, 10, 16 hours), and the results were correlated and discussed. Selected high-Ca limestones in this study are as much as > 98 wt%, but they are somewhat diverse in crystallinity, texture, and impurity composition. Synthesized quicklimes are varied depending on such a difference in ore characters. The Pungchon limestone has relatively very low calcination rate, and the limestones from the Gabsan formation and the Jeongseon formation exhibit good quality in calcination rate and decrepitation. Among these samples, the limestone ore from the Jeongseon formation is evaluated to be the best for crude ore in manufacturing of highly-reactive quicklime. In addition, it is characteristic that the Gabsan limestone comparative rich in Fe-bearing mineral such as pyrite and goethite is more conspicuous in sintering effect.

Quantitative Analysis and Archaeometric Interpretation for Molten Glass and Bronze Materials within Baekje Crucibles from the Ssangbukri Site in Buyeo, Korea (부여 쌍북리유적 출토 백제 도가니 내부 유리 및 청동 용융물질의 정량분석과 고고과학적 해석)

  • Lee, Chan-Hee;Park, Jin-Young;Kim, Ji-Young
    • Journal of Conservation Science
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    • v.26 no.2
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    • pp.157-169
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    • 2010
  • This study focused on the material characteristics and archaeometric relationship between the molten glass and bronze materials within the crucibles and gilt-bronze Bodhisattva statue excavated from the Ssangbukri site in Buyeo, Korea. Yellowish green to red brown vitreous material in the crucibles was identified as lead glass which contained scarce amount of BaO, and low $Al_2O_3$ and CaO. Metallic molten material was identified as bronze of copper-tin-lead alloy with low amount of impurities that indicated well-refined materials. Also, cassiterite was used for raw metal ore of tin. The Bodhisattva statue consisted of major copper with trace impurities in the core metal, and gold amalgam in the gilded layer. Though lead isotopic analysis showed contradictory results in each lead glass, bronze and Bodhisattva statue that required further examination, it could be stated that the statue was made in the Ssangbukri site based on the high-level technical skills of bronze production.

Size-resolved Source Apportionment of Ambient Particles by Positive Matrix Factorization at Gosan, Jeju Island during ACE-Asia (PMF 분석을 이용한 ACE-Asia 측정기간 중 제주 고산지역 입자상 물질의 입경별 발생원 추정)

  • Moon K.J.;Han, J.S.;Kong, B.J.;Jung, I.R.;Cliff Steven S.;Cahill Thomas A.;Perry Kelvin D.
    • Journal of Korean Society for Atmospheric Environment
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    • v.22 no.5
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    • pp.590-603
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    • 2006
  • Size-and time-resolved aerosol samples were collected using an eight-stage Davis rotating unit for monitoring (DRUM) sampler from 23 March to 29 April 2001 at Gosan, Jeju Island, Korea, which is one of the super sites of Asia-Pacific Regional Aerosol Characterization Experiment(ACE-Asia). These samples were analyzed using synchrotron X-ray fluorescence for 3-hr average concentrations of 19 elements including Al, Si, S, Cl, K, Ca, Ti, V, Cr, Mn, Fe, Ni, Cu, Zn, As, Se, Br, Rb, and Pb. The size-resolved data sets were then analyzed using the positive matrix factorization(PMF) technique to identify possible sources and estimate their contributions to particulate matter mass. PMF analysis uses the uncertainty of the measured data to provide an optimal weighting. Twelve sources were resolved in eight size ranges($0.09{\sim}12{\mu}m$) and included continental soil, local soil, sea salt, biomass/biofuel burning, coal combustion, oil combustion, municipal incineration, nonferrous metal source, ferrous metal source, gasoline vehicle, diesel vehicle, and volcanic emission. The PMF result of size-resolved source contributions showed that natural sources represented by local soil, sea salt, continental soil, and volcanic emission contributed about 79% to the predicted primary particulate matter(PM) mass in the coarse size range ($1.15{\sim}12{\mu}m$) while anthropogenic sources such as coal combustion and biomass/biofuel burning contributed about 58% in the fine size range($0.56{\sim}2.5{\mu}m$). The diesel vehicle source contributed mostly in ultra-fine size range($0.09{\sim}0.56{\mu}m$) and was responsible for about 56% of the primary PM mass.

Relationships between the Nutrient Intake Status, Dietary Habits, Academic Stress and Academic Achievement in the Elementary School Children in Bucheon-si (부천시 일부 초등학생의 영양소 섭취상태, 식습관, 학업스트레스와 학업성취도와의 관련성 연구)

  • Kim, Seol-A;Lee, Bog-Hieu
    • Journal of Nutrition and Health
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    • v.41 no.8
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    • pp.786-796
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    • 2008
  • This study examined the influence of the nutrient intake status, dietary habit, and academic stress of elementary school children on their academic achievement. Two-hundred and twenty-four fifth-graders in Bucheon-si, Gyeonggido were surveyed. The study included the 24 hr-recall, anthropometric measurement, assessment of stress level and academic achievement. The subjects were normal in height, weight and Rohrer index, but higher percentage of underweight was seen in girls and vice versa in boys. The overall nutrient intake and dietary habits were fairly good, but Ca and folate intake was less than 75% KDRIs and dietary habits of boys were inferior. Academic stress level of all the subjects was not high. In terms of academic performance and its relations with nutrient intake, the more the amount of nutrient intake, the higher the academic performance. Especially, it was true for the energy, protein, phosphorus, potassium, zinc, polyunsaturated fatty acids, and n-6 fatty acid intakes (p < 0.05). The overall academic performance was higher for those who eating-out less frequently. Children with higher comprehensive dietary habit scores have shown better academic performance (p < 0.05). Less stress implied to those shown higher academic achievement while those with relatively poor academic performance showed high stress level since their grade did not improve as much as they anticipated. In conclusion, the academic achievement was higher for those who have a better nutritional status, better dietary habits, and lower stress levels. Therefore, it is critical for nutritionists, parents, and teachers to improve the nutritional status and dietary habits as well as to help them manage their stress levels, which will eventually contribute to an enhanced academic performance.