• Title/Summary/Keyword: C.E.C

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Prevalence of virulence and cytolethal distending toxin (CDT) genes in thermophilic Campylobacter spp. from dogs and humans in Gyeongnam and Busan, Korea

  • Cho, Hyun-Ho;Kim, Sang-Hyun;Min, Wongi;Ku, Bok-Kyung;Kim, Yong-Hwan
    • Korean Journal of Veterinary Research
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    • v.54 no.1
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    • pp.39-48
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    • 2014
  • The prevalence of thermophilic Campylobacter (C.) spp. in stray, breeding, and household dogs was 25.2, 12.0, and 8.8%, respectively. C. jejuni and C. upsaliensis were the predominant Campylobacter spp. from household dogs. cdtA, cdtB, and cdtC were detected by PCR in all isolates. Despite the high cytolethal distending toxin (CDT) gene prevalence, only 26 (31%) C. jejuni strains and one (15.3%) C. coli strain showed evidence of CDT production in HEp-2 cell cytotoxicity assays. Virulence-associated genes detected in the C. jejuni and C. coli isolates were cadF, dnaJ, flaA, racR, ciaB, iamA, pldA, virB11, ceuE, and docC. cadF, dnaJ, flaA, and ceuE were found in all C. jejuni and C. coli isolates. When detecting Guillain-Barr$\acute{e}$ syndrome-associated genes (galE, cgtB, and wlaN), galE was identified in all isolates. However, cgtB and wlaN were more prevalent in C. jejuni isolates from humans than those from dogs. Adherence and invasion abilities of the C. jejuni and C. coli strains were tested in INT-407 cells. A considerable correlation (adjusted $R^2$= 0.678) existed between adherence and invasion activities of the Campylobacter spp. isolates.

Syntheses and Biological Activities of Potential Antifungal Allylamine Compounds (항진균 알릴아민 화합물의 합성과 활성평가)

  • Chung Byung-Ho;Cheon Seung-Hoon;Chung Soon-Young
    • YAKHAK HOEJI
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    • v.49 no.4
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    • pp.299-305
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    • 2005
  • Structure-activity relationship studies of allylamine type of antimycotics were carried out to evaluate the effect of naphthyl and methyl portion of naftifine. Compounds with 3,4-difluorophenyl (2a-5a), 4-hydroxyphenyl (2b-5b), 3-nitro­phenyl (2c-5c), 4-chlorobenzothiazoly (2d-5d) and 5-methylfurfural (2e-5e) instead of naphthyl group, and with hydrogen (3a-3e), methyl (4a-4e) and ethyl (5a-5e) in the place of methyl in naftifine were synthesized and tested for their in vitro anti-fungal activities against five different fungi. Fourteen compounds (3a, 4a, 5a, 3b, 4b, 5b, 3c, 4c, 5c, 3d, 4d, 3e, 4e and 5e) showed significant anti-fungal activities against T. mentagrophytes. (E)-N-(3-Phenyl-2-propenyl)-3,4-difluoro-ben­zenemethaneamine(3a), (E)_N_(3_phenyl_2_propenyl)_4_hydroxy_benzenemethaneamine(3b) and (E)-N-ethyl-N-(3-phenyl­2-propenyl)-3-nitro-benzenemethaneamine (5c) displayed moderate anti-fungal activities against all five different fungi.

Evaluation of Permeability Characteristics of Kimhae Clay by Laboratory Tests. (실내실험을 통한 김해점토의 투수특성 평가)

  • 김동휘;임형덕;김진원;이우진
    • Proceedings of the Korean Geotechical Society Conference
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    • 2000.03b
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    • pp.647-654
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    • 2000
  • During consolidation, the permeability of clay decreases with void ratio because of the reduction in total void space. After Kozeny(1927) and Carman(1956), many researchers have proposed the relations between void ratio and permeability. Most of the relations are expressed in the following forms as : (1) log e - log k(1+e), (2) e - log k, or (3) log e - log k. These relations have been found valid for a large number of normally consolidated clays. From laboratory test(CRS and I $L_{CON}$) results, the relation between void ratio and permeability of Kimhae clay was well defined in all of the three forms. Permeability change index, $C_{k}$, of Kimhae clay was in the range of 0.64~1,03 and average value of $C_{k}$ was 0.821. And the test results satisfied the experimental correlation between $C_{k}$ and e, $C_{k}$=0.5e. In log e - log k(1+e) relation, constant C was in the range of 1.91~4.74$\times$10$^{-8}$ cm/sec and n was in the range of 3.74~4.60.c and n was in the range of 3.74~4.60.74~4.60.0.

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A study on the Dielectric Properties of IPN based on the Epoxy/Silicon and Epoxy/Urethane (Epoxy/Silicon Epoxy/Urethane계 IPN 복합재료의 개발에 관한 연구)

  • Shin, Joong-Hong;Jung, Eun-Shik;Park, Chung-Hoo
    • Proceedings of the KIEE Conference
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    • 1987.11a
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    • pp.504-507
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    • 1987
  • Interpenerating Polymer Networks (IPNs) are unique type of polymer blend, synthesized by swelling a crossed polymer (Epoxy) with second polymer (Silicon) and also we adopted Urethane as the second polymer. The relationship between dielectric and mechanical properties of high temperature curing IPNs(E/S, E/U) are investigated. The ratios of weight that we formed we re two kind of thing, one (E/S) about 1[wt%]. 3[wt%], 5[wt%], 7[wt%], 10[wt%], and the other (E/U) about 5[wt%], 15[wt%], 25[wt%]. It was heat-cured for 24hours at $100^{\circ}C$ 48 hours at $10^{\circ}C$, 5 hours at $130^{\circ}C$, 15hours at $130^{\circ}C$ in E/S and also for 5 hours at $130^{\circ}C$ in E/U. From the viewpoint of dielectric and mechanical properties, the optimum condition is obtained from the sample cured for 5hours at $130^{\circ}C$ for 1[wt%] in the E/S, and also obtained from the sample cure d for 5 hours at $130^{\circ}C$ in E/U.

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Effect of Antioxidant Vitamin Supplementation on Plasma Lipid Pattern in Smoking College Men (항산화성 비타민 보충 급여가 흡연자의 혈중 지질 양상에 미치는 영향)

  • 이성숙
    • Journal of Nutrition and Health
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    • v.31 no.3
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    • pp.297-304
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    • 1998
  • Cigarette smoking is a well known risk factor for cardiovascular disease and has negative effects on blood lipid and lipoprotein . Some of the associations between smoking and chronic disease can be attributed to the less healthful lifestyles of smokers. A large body of epidemiologic evidence suggests inverse relationships between ischemic heart disease and plasma vitamin C and E concentrations . Smokers have lower plasma concentrations of these vitamins than do nonsmokers. Smokers therefore need antioxidant vitamin supplementation. The purpose of this study was to investigate the effect vitamin supplementation on plasma lipid patterns in smoking college men. 24subjects were divided into 3 groups of which were the vitamin C supplementation group (n=8), the vitamin E supplementation group(n=8) and the vitamin C+E supplementation group(n=8). The vitamin C supplementation group consumed 500mg of ascorbic acid, the vitamin E supplementation group consumed 200IU of D-$\alpha$-tocopherol, and the vitamin C+E supplementation group consumed 500mg of ascorbic acid+ 200IU of D-$\alpha$-tocopherol for 4 weeks. We examined the plasma lipid patterns before and after the vitamins were supplemented. The results obtained were as follows ; In the vitamin C supplementation group, the concentration of total cholesterol decreased significantly and HDL-cholesterol increased significantly with the supplementation of vitamin. In the vitamin E and vitamin C+E supplementation groups, however, there were no significant differences observed with the supplementation of vitamin. Concentration of plasma LDL, triglyceride, free fatty acid were not significantly affected by the supplementation of vitamin in all groups. In terms of plasma fatty acid composition, the concentrations of saturated fatty acid were not significantly affected by the supplementation of vitamin in all groups. The concentrations of palmitoleic acid, arachidonic acid, and docosahexaenoic acid, however, significantly increased in the vitamin E supplementation group(p<0.05). The concentration of plasma linoleic acid significantly increased in the vitamin C+ E supplementation group)(p<0.05). The results of this study show that antioxidant vitamin supplementation in smokers has a tendency to decrease coronary heart disease risk in view of the plasma total cholestrol and HDL-cholesterol concentrations of the vitamin C supplementation group and fatty acid concentration of the vitamin E supplementation group.

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The Effects of Dietary Supplementation of Vitamin C or E on the Expressions of Endoplasmic Reticulum Stress, Lipid and Glucose Metabolism Associated Genes in Broiler Chickens (비타민 C 및 E의 첨가 급여가 육계의 소포체 스트레스와 지방 및 포도당 대사 연관 유전자의 발현에 미치는 영향)

  • Park, Jeong Geun;An, Young Sook;Sohn, Sea Hwan;Jang, In Surk;Moon, Yang Soo
    • Korean Journal of Poultry Science
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    • v.40 no.2
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    • pp.147-155
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    • 2013
  • This study was conducted to evaluate the effects of dietary supplementation of vitamin C or E on the expressions of endoplasmic reticulum (ER) stress, lipid and glucose metabolism associated genes in broiler chickens. A total of 216 one-day-old male broilers was randomly alloted to 4 treatments with 6 replicate pens per treatment and 9 broilers per pen for 35 days. The dietary treatments were control, vitamin C (control diet + ascorbic acid 200 mg/kg diet), vitamin E (control diet + ${\alpha}$-tocopherol 100 mg/kg diet), vitamin C + E (control diet + vitamin C 200 mg/kg + vitamin E 100 mg/kg), respectively. To evaluate gene expressions by quantitative real-time polymerase chain reaction, total RNA was extracted from the liver of the chicken at 35 days of age. Dietary supplementation of vitamins was significantly down-regulated the expression of stress marker genes including HSP70, HSP90, and HMGCR, as compared to the control (p<0.05). The expressions of ER stress associated genes also inhibited by supplementation of vitamins as well (p<0.05). Vitamin C supplementation suppressed the expression of lipid associated genes such as FASN, FATP1 and ACSL1. Vitamin supplementation did not affect the glucose transporters, GLUT2 and GLUT8, in the liver. The results of the present study indicated that dietary supplementation of vitamin C or E could be beneficial for the alleviating physiological stress in broiler chickens.

A GDD Model for Super Sweet Corn Grown under Black P. E. Film Mulch (흑색 P. E. Film 피복에서 초당옥수수의 생육기간을 표시하는 GDD모델 개발)

  • Lee, Suk-Soon;Yang, Seung-Kyu;Hong, Seung-Beom
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.53 no.1
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    • pp.42-49
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    • 2008
  • GDD models of corn were developed in bare soil, while sweet and super sweet corns are grown under black polyethylene (P. E.) film mulch in Korea. To develop a suitable GDD model under black P. E. film mulch, a super sweet com hybrid "Cambella-90" was planted from 1 April to 30 June in 2003 at the 10-day intervals under black P. E. film mulch and in bare soil. In bare soil the best GDD model was $GDD\;=\;{\sum}[H"+L')/2\;-\;10^{\circ}C]$, where H" was daily maximum temperature but is was substituted for $30^{\circ}C$ - (daily maximum temperature - $30^{\circ}C$) when higher than $30^{\circ}C$ and L' was daily minimum temperature, but it was substituted for $10^{\circ}C$ when lower than $10^{\circ}C$. The same GDD model could be adapted for com grown under black P. E. film mulch, but base temperature was substituted for $9^{\circ}C$. To determine planting date for the scheduled harvests, accumulated GDDs were calculated using 30-year average temperature data during the growing season. Under black P. E. film mulch planting dates were determined by subtracting GDD of the hybrid, $970^{\circ}C$, from accumulated GDD of scheduled harvest dates.

ON RELATIVE-INVARIANT CIRCULAR UNITS IN FUNCTION FIELDS

  • JUNG, HWANYUP
    • Honam Mathematical Journal
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    • v.27 no.3
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    • pp.389-397
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    • 2005
  • Let K be an absolutely real abelian number field with $G=Gal(K/{\mathbb{Q}})$. Let E be a subfield of K and ${\Delta}=Gal(K/E)$. Let $C_K$ and $C_E$ be the group of circular units of K and E respectively. In [G], Greither has shown that if G is cyclic then $C_K^{\Delta}=C_E$. In this paper we show that the same result holds in function field case.

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