• 대한한방내과학회지
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• 제25권4호
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• pp.167-176
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• 2004

Objectives : This study was designed to report the clinical effects of scalp acupuncture on patients who suffered from broca aphasia caused by cerebral hemorrhage, Methods : Scalp acupuncture therapy was applied on the above patients for several weeks, For the evaluation of improvement, language field was monitored by aphasia test(RISS) and speech field was monitored by phonetic analysis in the computerized speech lab. Results : According to the above evaluation items, the treatment was beneficial. The score of most items rose in the language field. And scalp acupuncture affected VOT, TD and articular error patterns positively in the speech field. Conclusions : The above results suggest that scalp acupuncture has good effects on the patients with broca aphasia caused by cerebral hemorrhage.

• 대한한방내과학회지
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• 제22권3호
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• pp.423-430
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• 2001

Objects: The purpose of this case-control study was done to examine the relationship between stroke prevalence and the anthropometric indices(body mass index(BMI), modified Broca's method(Broca's index), waist circumference(WC), waist-hip ratio(WHR)), dyslipidemia, past medical history(heart disease, hypertension, diabetes mellitus(DM)), life-style factors(smoking, drinking) in Korean adults. Methods : The study group consisted of neurologically confirmed 116 stroke patients as the case group and 116 non-stroke patients as control group. Obesity were defined as $BMI{\geq}25kg/m^2,\;Broca's\;index{\geq}30%$, WC >94cm in male and WC >80cm in female, $WHR{\geq}0.9$ in male and $WHR{\geq}0.8$ in female. Oyslipidemia were defined as total $cholesterol{\geq}200mg/dl,\;triglyceride{\geq}200mg/dl,\;HDL-cholesterol {\leq}35mg/dl,\;LDL-cholesterol{\geq}160mg/dl$. Information on life-style factors and past medical history was obtained from personal interview. The analysis of the data was done by means of chi-square test(Pearson's chi-square test, Fisher's exact test) and student t-test. Results: The results were as follow. In the study group: Hypertension had a 4:05 odds ratio, Broca's $index{\geq}30%$ had a 1.98 odds ratio, WC >94cm in male had a 2.17 odds ratio, WC >80cm in female had a 2.80 odds ratio, $WHR{\geq}0.9$ in male had a 4.66 odds ratio, $WHR{\geq}0.8$ in female had a 5.35 odds ratio, but heart disease, DM, life-style factors, serum lipid and 8MI had no direct relationship with odds ratio(nonsignificant). By student t-test, risk factors for stroke were found to be total cholesterol(p=0,025), LDL-cholesterol(p=0.013), WC(p=0.000) and WHR(p=0.000). Conclusions: This study suggests that people should be advised to control hyperlitension, hyperlipidemia and obesity since these carry a risk of stroke.

• 한국산학기술학회논문지
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• 제12권11호
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• pp.5005-5011
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• 2011

본 연구는 자기공명영상을 이용한 뇌 언어 인지기능의 영상화에 있어서 기존의 text를 이용한 자극방법의 단점을 개선하기 위하여 음절이나 단어에 부합하는 image를 자체 개발하여 적용함으로써 인지기능 영상화 구현의 타당성을 알아보고자 하였다. 연구대상은 2011년 3월부터 동년 5월까지 언어기능검사가 필요한 성인 5명을 대상으로 text를 이용한 자극방법과 text를 대체한 image를 이용한 자극방법으로 나누어 각각 3회 시행하였다. 실험 장비는 3.0T 초전도 자기공명영상장치와 Invivo사의 Eloquene를 이용하였고, EPI-BOLD 기법으로 기능적 자기공명영상을 획득하였다. 영상의 후처리는 SPM 99를 이용하여 각 자극별로 95%의 신뢰수준에서 활성화 신호를 결정하였고, 관심영역인 Broca's area의 활성화 cluster 수와 활성화도를 비교하였다. 연구결과, 5명 모두 관심 영역인 Broca's area에서 활성화를 보였으며, 활성화 cluster 수와 활성화도는 약간의 차이가 있었으나, 통계적 유의성은 없었다. 결론적으로 image를 이용한 자극방법은 언어장벽이 있더라도 image 자체가 쉽게 인지할 수 있는 공통된 인식표기 수단이고 단어나 음절보다 시각적 효과가 크므로 인지기능이 저하된 외국인이나 문맹자나 영유아, 장애자, 노약자 등의 검사시 text를 이용한 자극방법의 대체가 가능하리라 사료된다.

• Korean Journal of Radiology
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• 제24권6호
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• pp.553-563
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• 2023

Objective: Functional magnetic resonance imaging (fMRI) and diffusion tensor imaging-derived tractography (DTI-t) contribute to the localization of language areas, but their accuracy remains controversial. This study aimed to investigate the diagnostic performance of preoperative fMRI and DTI-t obtained with a simultaneous multi-slice technique using intraoperative direct cortical stimulation (DCS) or corticocortical evoked potential (CCEP) as reference standards. Materials and Methods: This prospective study included 26 patients (23-74 years; male:female, 13:13) with tumors in the vicinity of Broca's area who underwent preoperative fMRI and DTI-t. A site-by-site comparison between preoperative (fMRI and DTI-t) and intraoperative language mapping (DCS or CCEP) was performed for 226 cortical sites to calculate the sensitivity and specificity of fMRI and DTI-t for mapping Broca's areas. For sites with positive signals on fMRI or DTI-t, the true-positive rate (TPR) was calculated based on the concordance and discordance between fMRI and DTI-t. Results: Among 226 cortical sites, DCS was performed in 100 sites and CCEP was performed in 166 sites. The specificities of fMRI and DTI-t ranged from 72.4% (63/87) to 96.8% (122/126), respectively. The sensitivities of fMRI (except for verb generation) and DTI-t were 69.2% (9/13) to 92.3% (12/13) with DCS as the reference standard, and 40.0% (16/40) or lower with CCEP as the reference standard. For sites with preoperative fMRI or DTI-t positivity (n = 82), the TPR was high when fMRI and DTI-t were concordant (81.2% and 100% using DCS and CCEP, respectively, as the reference standards) and low when fMRI and DTI-t were discordant (≤ 24.2%). Conclusion: fMRI and DTI-t are sensitive and specific for mapping Broca's area compared with DCS and specific but insensitive compared with CCEP. A site with a positive signal on both fMRI and DTI-t represents a high probability of being an essential language area.

• Journal of Korean Neurosurgical Society
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• 제59권3호
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• pp.306-309
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• 2016

Using diffusion tensor tractography (DTT), we demonstrated injury of the arcuate fasciculus (AF) in the nondominant hemisphere in two patients who showed subfalcine herniation after intracerebral hemorrhage (ICH) in the dominant hemisphere. Two patients (patient 1 and patient 2) with ICH and six age-matched control patients who have ICH on the left corona radiata and basal ganglia without subfalcine herniation were recruited for this study. DTT was performed at one month after onset in patient 1 and patient 2. AFs of both hemispheres in both patients were disrupted between Wernicke's and Broca's areas. The fractional anisotropy value and tract numbers of the right AFs in both patients were found to be more than two standard deviations lower than those of control patients. In contrast, the apparent diffusion coefficient value was more than two standard deviations higher than those of control patients. Using the configuration and parameters of DTT, we confirmed injury of the AF in the nondominant hemisphere in two patients with subfalcine herniation following ICH in the dominant hemisphere. Therefore, DTT would be a useful tool for detection of underlying injury of the AF in the nondominant hemisphere in patients with subfalcine herniation.

• 인지과학
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• 제9권1호
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• pp.41-46
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• 1998

이 논문에서는 뇌졸중으로 인한 Broca 유형의 실어증 환자가 회복 초기와 회복이 진행됨에 따라 발화하는 서술어의 논항 구조적 속성이 정상 언어 집단의 서술어 분포와 어떻게 다르며, 또한 편으로는 전도 실어증 환자의 서술어 분포와는 어떻게 다른지 세 환자와, 조건이 비슷한 정상인의 자유 발화 산출 자료를 분석하여 비교한다. Broca 유형 실어증 환자가 발화하는 서술어 중에서 비대격 동사가 차지하는 비율을 언어간 비교해 본 결과, 영어 실어증 환자의 경우에는 계사가 아닌 비대격 동사에 심한 어려움을 겪어 거의 산출되어 못하는 것으로 나타난 반면(Kegl 1995), 한국어 실어증 환자의 경우에는 별다른 어려움을 겪지 않는 것으로 나타났다. 이에 대한 설명으로 영어의 비계사 비대격 구문에서는 d-구조와 s-구조 사이에서 동사에 상대적인 논항 이동이 일어나는 데 반해, 한국어에서는 격 부여라는 동기로 유발되는 그러한 논항 이동이 없거나, 설사 있더라도 공허하기(vacuous) 때문에 비문법적 실어증 환자들이 어려움을 느끼지 않으리라는 제안을 한다.

• 대한한방내과학회지
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• 제25권4호
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• pp.401-409
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• 2004

Aphasia is a dysfunction in recognition and communication, Most instances of aphasia are caused by cerebral disease, especially when a dominant hemisphere is injured. It brings about serious problem in treatment and in directing a therapeutic course for return to social community. A stroke patient who was adimitted Dongguk Bundang Oriental hospital was treated. This subject was diagnosed with Broca Aphasia and Flaccid Tongue(舌?) induced by Yang-deficiency of Kidney(腎陽虛). She was adiministered Jiwhangeumja(地黃飮子) and Scalp acupuncture, and the degree of her aphsia was measured with the Western Aphasia Battery. After three weeks, The patient improved in speaking and general depressed condition.

• 음성과학
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• 제7권3호
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• pp.263-272
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• 2000

The purpose of this study was to compare receptive language performance and expressive language performance in 13 patients with aphasia by using three stimulus presentation modes: Stimulus mode I (picture), Stimulus mode II (written word), Stimulus m (question using verbal explanation). The stimulus consisted of 10 words. They included 5 functional words and 5 non-functional words. The 13 subjects with aphasia were divided into 2 aphasic types: 5 Broca's aphasics and 8 anomie aphasics. The results were as follows: Firstly, the three stimulus modes didn't affect receptive language performance of aphasia subjects. Secondly; the three stimulus modes were effective on expressive language performance of aphasia subjects. Particularly, stimulus mode II (written words) was effective in naming the aphasia subjects. Thirdly, the functional words with high frequency were better than non-functional words with low frequency on expressive language performance, but not on receptive language performance of aphasia subjects. Finally, the interaction between three stimulus modes and the functional (nonfunctional) words affected expressive language performance only, but not receptive language performance. Particularly, presenting stimulus in written words which are functional words produced the best expressive language performance.

• 동아시아식생활학회지
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• 제15권2호
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• pp.152-157
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• 2005

The purpose of this study was to investigate dietary habit and to evaluate nutritional status and obesity index about adults living in Daejon area. This study was conducted with 250 subjects (male 130, female 120) who visited periodically a periodic health center in a general hospital from May to June in 2002. Questionaries were used for studying of dietary habit and food frequency method. Dietary intake was assessed by food frequency method and consumption of foods and nutrients was analyzed. The relationship between dietary habit and obesity were also analyzed. Dietary habit was better in female than mail. There was no significant difference in mean of Broca's index between female ($110.6\pm16.6\%$) and male ($110.0\pm13.7\%$). The obesity group showed low dietary habit score in irregular eating behavior, frequent eating out and over-intake of salty foods. Especially mean intakes of energy were lower than Korean RDA in all groups. All groups except obesity group were deficiency of vitamin A and vitamin $B_{1}$ and calcium.

• 대한가정학회지
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• 제31권1호
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• pp.153-162
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• 1993

The purpose of this study is to demonstrate the physical consciousness of two groups, the high school girl(335) and the female college students(246), about their actual somatotype and cognitive comatotype, and to investigate it in comparison with the R hrer Index, the BMI Index, and the Broca-Katsura Index to find if there is any difference between the two groups. The results are as follows; A. In the light of cognitive somatotype by self-evaluation:(1) both high school girls and female college students recognized their weight and somatotype as normal and balanced with no significant difference between them. (2) bout groups indicated that their answers were the results of their own self-evaluation, and it was shown that there was a significant difference between the two groups. B. According to the actual somatotype based on Index. (1) it was shown there was a significant difference between the cognitive somatotype and the actual one of the tow respective groups when based on the Broca Katsura Index. (3) there was a significant difference between the cognitive somatotype and the actual one of the two respective groups when based on the Rohrer Index. Finally, it was shown that there was a significant difference between the two groups.