• 대한영상의학회지
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• 제85권2호
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• pp.421-427
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• 2024

이소성 유방조직은 겨드랑이에서 사타구니 선까지 유방 능선을 따라 발생할 수 있으며 가장 일반적으로 발생하는 부위는 겨드랑이이다. 이소성 유방조직에서 발생하는 원발성 암종은 극히 드물다. 왼쪽 겨드랑이에 부유방조직을 절제한 병력이 있는 61세 여성이 왼쪽 겨드랑이에 만져지는 종괴로 내원하였고 종괴의 평가를 위해 액와미부 촬영을 포함한 유방촬영술, 초음파 및 유방 MRI를 시행하였으며 특히 액와미부 촬영으로 왼쪽 겨드랑이의 특징적인 악성미세석화화의 양상과 범위를 평가하였다. 초음파 유도하 생검술을 통해 이 병변은 침윤성 유방암으로 진단되었고 조영증강 복부 CT에서 다발성 간전이가 확인되어 환자는 이후 고식적 항암요법을 받았다. 저자들은 겨드랑이 부유방 조직에서 발생한 드문 원발성 유방암에 대해 액와미부 촬영을 시행한 증례를 보고하고자 한다.

• 근관절건강학회지
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• 제19권1호
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• pp.5-15
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• 2012

Purpose: The purpose of this study was to analyze the effects of a combined exercise program on the level of physical fitness and fatigue for cancer survivors. Methods: The subjects were all of 61 persons consisted of prostate cancer(n=22), breast cancer (n=20), and stomach cancer(n=19) survivors. The exercise program was composed of a wall exercise, a chair exercise, a towel exercise and a bottle exercise which lasted 50-60 minutes each, two times a week for 12 weeks. The outcome measures were the fat mass, the muscle mass, the grip strength, the sit and reach, the 6 minutes walk, & fatigue. Results: At the completion of the 12-week combined exercise program, there were statistically significant differences in the grip strength, the sit & reach, the 6 minutes walk, & fatigue for the prostate, breast, and stomach cancer survivors. But no significant differences were found in the muscle mass between the pretest and posttest. Conclusion: As the 12-week combined exercise program was proved to be an effective intervention for improving muscle strength, flexibility, cardiopulmonary fitness & fatigue, it is thought that the program can be utilized as a rehabilitation program for cancer survivors.

• 대한세포병리학회지
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• 제8권2호
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• pp.160-163
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• 1997

The cytologic finding of proliferating trichilemmal tumor is not well documented and have difficulties in the cytological analysis of the fine needle aspirates. This rare dermatopathologic entity may be encountered during aspiration biopsy of subcutaneous masses, and is, occasionally, confused with other neoplasm, particulary squamous carcinoma owing to its close cytological resemblance. We report a case of proliferating trichilemmal tumor in the left breast. The patient is a woman and had a lump in the breast for 20 years. Fine needle aspiration revealed a few small clusters of squamoid cells in the background of amorphous and calcified material. After excisional biopsy, the mass was confirmed as proliferating trichilemmal tumor. The main cytologic features discriminating squamous cell carcinoma were bland nature of epithelial cells, absence of atypical dyskeratotic cells, and rich amount of amorphous material.

• Asian Pacific Journal of Cancer Prevention
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• 제16권18호
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• pp.8659-8663
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• 2016

In Nepal, while no population based cancer registry program exists to assess the incidence, prevalence, morbidity and mortality of cancer, at the national level a number of hospital based cancer registries are cooperating to provide relevant data. Seven major cancer diagnosis and treatment hospitals are involved, including the BP Koirala Memorial Cancer hospital, supported by WHO-Nepal since 2003. The present retrospective analysis of cancer patients of all age groups was conducted to assess the frequencies of different types of cancer presenting from January 1st to December 31st 2012. A total of 7,212 cancer cases were registered, the mean age of the patients being 51.9 years. The most prevalent age group in males was 60-64 yrs (13.6%), while in females it was 50-54 yrs (12.8%). The commonest forms of cancer in males were bronchus and lung (17.6%) followed by stomach (7.3%), larynx (5.2%) and non Hodgkins lymphoma (4.5%). In females, cervix uteri (19.1%) and breast (16.3%), were the top ranking cancer sites followed by bronchus and lung (10.2%), ovary (6.1%) and stomach (3.8%). The present data provide an update of the cancer burden in Nepal and highlight the relatively young age of breast and cervical cancer patients.

• Journal of Gastric Cancer
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• 제14권3호
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• pp.215-219
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• 2014

Distant metastasis from papillary thyroid carcinoma (PTC), particularly from papillary thyroid microcarcinoma, is rare. We present a case of perigastric lymph node metastasis from PTC in a patient with early gastric cancer and breast cancer. During post-surgical follow-up for breast cancer, a 56-year-old woman was diagnosed incidentally with early gastric cancer and synchronous left thyroid cancer. Therefore, laparoscopic distal gastrectomy with lymph node dissection and left thyroidectomy were performed. On the basis of the pathologic findings of the surgical specimens, the patient was diagnosed to have papillary thyroid microcarcinoma with perigastric lymph node metastasis and early gastric cancer with mucosal invasion. Finally, on the basis of immunohistochemical staining with galectin-3, the diagnosis of perigastric lymph node metastasis from PTC was made. When a patient has multiple primary malignancies with lymph node metastasis, careful pathologic examination of the surgical specimen is necessary; immunohistochemical staining may be helpful in determining the primary origin of lymph node metastasis.

• 대한간호학회지
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• 제44권2호
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• pp.139-148
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• 2014

Purpose: This study was conducted to identify the factors influencing second primary cancer (SPC) screening practice by examining the relationships of physical symptoms, knowledge and attitudes regarding SPC screening, perceived risk, primary cancer type, and demographic factors of cancer survivors. Methods: Participants were 308 survivors of stomach, colon, or breast cancer recruited from 2 university hospitals in Korea. Data were collected using a questionnaire and analyzed using IBM SPSS 21.0 and AMOS 18.0. Results: The proportion of participants taking all cancer screenings according to national guidelines was 40%. They had moderate knowledge and a relatively positive attitude regarding SPC screening and high cancer risk perception. The participants had taken fewer SPC screenings after than before cancer diagnosis. The factors influencing cancer risk perception were age, physical symptoms, knowledge regarding SPC and primary cancer type (stomach). The factors influencing SPC screening practice were age, gender, economic status, knowledge regarding SPC screening, and primary cancer types (colon). Conclusion: It is important for clinical professionals to recognize that survivors of cancer are susceptible to another cancer. Education on SPC screening for these survivors should focus on communicating with and encouraging them to have regular cancer screenings.

• 대한두개안면성형외과학회지
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• 제14권1호
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• pp.65-68
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• 2013

Muir-Torre syndrome is defined by concurrent or sequential development of internal malignancy and sebaceous neoplasm or multiple keratoacanthomas. Muir-Torre syndrome is very rare, with only 205 cases reported in the literature. We reported a patient with Muir-Torre syndrome with three internal malignancies. A 64-year-old patient with a history of breast cancer, stomach cancer and colon cancer visited our department for treatment of the skin lesion that occurred five years before on the left cheek. The lesion was excised completely with a resection margin of 1 cm, followed by full-thickness skin graft from left postauricular area for reconstruction. Histopathology revealed a $0.2{\times}0.2{\times}0.1cm$ sized sebaceous carcinoma with 4 mm safety margin. The skin graft was well taken within 7 days after surgery and the patient was discharged to outpatient follow-up. There was no complication related with surgery. Muir-Torre syndrome is very rare, as are sebaceous gland tumors. So if a cancer of the sebaceous gland is diagnosed, screening workup for internal malignancy is recommended. Because of its good prognosis, surgical removal of primary or metastatic cancers may be curative and should be attempted where possible.

• 대한영상의학회지
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• 제82권6호
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• pp.1606-1612
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• 2021

비대성 골관절증은 곤봉지, 근막골형성 및 윤활막 삼출액을 특징으로 하는 증후군이다. 이차성 비대성 골관절증은 대부분의 경우 흉부 내 악성 종양과 연관이 있으나, 드물게 흉강 외 악성 종양에 의해 발생할 수 있다. 이에 우리는 유방암의 과거력이 있는 환자에서 발생한 비대성 골관절증의 초음파, 전산화단층촬영, 자기공명영상 및 뼈 신티그래피의 초기 영상의학적 소견에 대해 서술하고자 한다. 악성 종양으로 오인된 본 증례의 모호한 임상 및 영상 소견은 독자에게 흥미롭고 유익할 것으로 생각된다.

• Asian Pacific Journal of Cancer Prevention
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• 제13권11호
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• pp.5385-5389
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• 2012

Introduction: Sentinel lymph node biopsy (SLNB) is a precise procedure for lymphatic staging in early breast cancer. In a valid SLNB procedure, axillary lymph node dissection (ALND) can be omitted in nodenegative cases without compromising patient safety. In this study, detection rate, accuracy and false negative rate of SLNB for breast cancer was evaluated in a setting with simple modified conventional pathology facilities without any serial sectioning or immunohistochemistry. Material and Medthod: Patients with confirmed breast cancer were enrolled in the study. SLNB and ALND were performed in all cases. Lymph node metastasis was evaluated in SLN and in nodes removed by ALND to determine the false negative rate. Pathologic assessment was carried out only by modified conventional technique with only 3 sections. Detection rate was determined either by lymphoscintigraphy or during surgery. Results: 78 patients with 79 breast units were evaluated. SLN was detected in 75 of 79 cases (95%) in lymphoscintigraphy and 76 of 79 cases (96%) during surgery. SLN metastases was detected in 30 of 75 (40%) cases either in SLNB and ALND groups. Accuracy of SLNB method for detecting LN metastases was 92%. False negative rate was 3 of 30 of positive cases: 10%. In 7 of 10 cases with axillary lymphadenopathy, LN metastastates was detected. Conclusion: SLNB is recommended for patients with various tumor sizes without palpable lymph nodes. In modified conventional pathologic examination of SLNs, at least macrometastases and some micrometastases could be detected similar to ALND. Consequently, ALND could be omitted in node-negative cases with removal of all palpable LNs. We conclude that SLNB, as one of the most important developments in breast cancer surgery, could be expanded even in areas without sophisticated pathology facilities.

• 한국산학기술학회논문지
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• 제18권11호
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• pp.454-458
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• 2017

섬유선종은 여성 유방의 가장 흔한 양성 종양이고, 대부분 악성병소로 변하지 않는 것으로 알려져 있다. 일상생활에 큰 지장을 주지 않는다면 주기적인 관찰만 하는 경우가 많다. 일반적으로 섬유선종에서의 악성화 병변이 발생하지 않는다고 알려져 있다. 또한 섬유선종 내에서 악성병변이 발생한다면 단지 영상 검사만으로 진단하기 힘들뿐 아니라, 치료를 위해 외과 의사가 수술 방향을 설정하는 것 역시 쉽지 않다. 저자는 19세와 51세의 여자 환자의 두 예에서 유방의 섬유선종에서 발생한 관상피내암을 경험하였다. 19세 여자환자는 만져지는 우측 유방 종괴를 주소로, 타병원에서 절제생검으로 진단하였고, 본원에서 주변부의 재절제술을 하였다. 또한, 면역검사결과 에스트로겐 수용체 및 프로게스테론 수용체 양성 소견을 보여 내분비 치료를 하였다. 51세 여자환자는 좌측 유방의 종괴를 주소로, 유방촬영술 검사에서 내부에 미세석회화 소견을 보였고, 이에 초음파를 이용한 조직검사로 진단하였으며, 자기공명영상 촬영 후 보존적 유방 절제술을 하였다. 유방의 섬유선종에서 발생한 악성병변에 대한 보고는 거의 없다. 또한 이에 대한 특성이나 치료에 대한 지침도 없다. 따라서 이러한 유형의 병변은 드물고 경험이 거의 없기 때문에 유방의 섬유선종에서 발생한 악성병변의 모든 예에 대한 영상검사 및 병리학적 특징을 정확히 이해한다면 유방의 섬유선종의 다양한 형태의 병변에 대한 보다 정확한 진단 및 치료를 시행하는데 많은 도움을 줄 것으로 생각된다. 이에 저자는 유방의 섬유선종에서 발생한 관상피내암의 2예를 바탕으로 섬유선종 내에서 발생한 악성병변의 특성 및 치료에 대해 문헌고찰과 함께 보고하는 바이다.