• Journal of Veterinary Clinics
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• v.35 no.3
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• pp.83-87
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• 2018

The aim of this study was to evaluate the biomechanical behavior of xenogenic bone plate system (equine bone) using a three-dimensional finite element ulna fracture model. The model was used to calculate the Von Mises stress (VMS) and stress distribution in fracture healing periods with metallic bone plate and xenogenic bone plate systems, which are installed while the canine patient is standing. Bone healing rate (BHR) (0%) and maximum VMS of the xenogenic plate was similar to the yield strength of equine bone (125 MPa). VMS at the ulna and fracture zones were higher with the xenogenic bone plate than with the metallic bone plate at BHRs of 0% and 1%. Stress distributions in fracture zone were higher with the xenogenic bone plate than the metallic bone plate. This study results indicate that the xenogenic bone plate may be considered more beneficial for callus formation and bone healing than the metallic bon plate. Xeonogenic bone plate and screw applied in clinical treatment of canines may provide reduced stress shielding of fractures during healing.

• Proceedings of the Materials Research Society of Korea Conference
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• 2009.11a
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• pp.43.1-43.1
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• 2009

Bone plate는 골절된 뼈의 골 유합을 지지하기 위해서 정형외과, 신경외과, 성형외과 및 치과 등에서 널리 사용되고 있다. 하지만 기존의 bone plate는 대부분 금속으로 제작되어 있어 장기간 이식에 따른 부식 및 천연골 강도저하 등으로 인해 1~2년 후 재수술을 해야 하는 문제점을 갖고 있다. 본 연구에서는이런 금속 bone plate의 단점을 개선하고자 생체적합성이 우수한 생분해성 고분자 bone plate를 제작하였다. 사용된 고분자는 생체적합성과 생분해성이우수한 PVA(polyvinly alcohol)와 강도를 유지하기 위한 PMMA(poly methyl methacrylate)를 사용였다. Electrospinning 법으로 PVA와 PMMA fibrous mat를 제작하여 각 mat를 적층시킨 후 열압착을 하여 강도를 증가시킨 PMMA/PVA Mutlilayer bone plate을 제작하였다. 제작된 PMMA/PVA Mutlilayer bone plate의 생체적합성 평가를 위해 MTT assay, 생분해 특성을 관찰하기 위해 Micro-CT와 SBF(simulated body fluid) 내에서의 용해도를 관찰하였다. 또한조골세포의 부착과 분화에 미치는 영향을 SEM(scanning electron microscope)을통해 관찰하였고, 조골세포의 유전자 발현에 미치는 영향을 RT-PCR을통해 확인하였다.

• Composites Research
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• v.20 no.5
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• pp.7-12
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• 2007

This paper aims to enhance the efficiency of bone fracture healing with bone plate made of fiber reinforced composite materials. The composite bone plate was designed as the same dimension and shape as the existing stainless steel bone plate. To find out the appropriate stacking sequence of the composite bone plate the variations of strain distributions were calculated using FE analysis when the bone plates were applied to the fracture site. From the analysis result it was found that the composite bone plate whose Young's modulus is lower than that of metal bone plate gave more uniform strain distribution and provided appropriate condition for callus formation and its development.

• Archives of Plastic Surgery
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• v.35 no.4
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• pp.419-422
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• 2008

Purpose: Absorbable bone fixation materials for operation of facial bone fracture are composed of poly- lactic acid(PLA) & poly-glycolic acid(PGA). These materials are absorbed after facial bone healing period. Therefore, these materials are harmless in human body. But because of it's radioopacity, the number and the location of the materials are not checked in follow-up X-ray examination. We studied absorbable bone fixation materials checked radiological examination. So, we made the absorbable plate composed of PLA, Hydroxyapatite (HA) and Gold(Au). Methods: Plate 1 was consisted of pure PLA. Plate 2 was consisted of PLA(50%) and HA(50%). Plate 3 - 7 were consisted of PLA(50%), and variable composition of HA & Au. The ratio of Au was as following. From the plate 3 to plate 7, the Au ratio was 1%, 5%, 10%, 17%, and 25%, respectively. Total 3 examinations were used-naked eye examination, simple X-ray examination, and Haunsfield unit of plate in CT examination. Results: Naked eye examination found out that the color of plate 1 was most white. As the Au ratio increases, the color of plate was getting close to khaki color. the radioopacity of plate 2 was similar cortical bone of face in simple X-ray. The Haunsfield unit of cortical bone of face was 1000 HU. Haunsfield unit of titanium plate was 2900 HU. Haunsfield unit of plate 1 through plate 7 were -242, 1489, 1776, 3052, 3092, 3095, and 3095, respectively. Conclusion: Radioopacity of plate 2 was similar to cortical bone of face. In CT examination, Hanusfield unit of plate 2 was similar to Hanusfield unit of cortical bone of face. Hanusfield unit of plate 4 - 7 were similar to Hanusfield unit of titanium plate. So to trace bone fixation materials after facial bone surgery, the best ratio of Au is about 1 - 5%. If this study is applied to facial bone surgery, radiologic follow up would be easy after facial bone surgery.

• The Korea Journal of Herbology
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• v.21 no.1
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• pp.63-69
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• 2006

Objectives : This study was designed to investigate the effects of Cervi Pantotrichum Cornu and Cervi Cornu on the growth of longitudinal bone in the adolescent male rats. Methods : Longitudinal bone growth was measured by fluorescence microscopy. To examine the effects on the growth plate metabolism, the heights of growth plate and the induction of local bone morphogenetic protein-2 were measured. Results : Treatment of Cervi Pantotrichum Cornu significantly enhanced longitudinal bone growth compared with control group. However, Cervi Cornu did not show the significant effects. Conclusion : Cervi Pantotrichum Cornu enhanced longitudinal bone growth and promoted the induction of local bone morphogenetic protein-2 of growth plate in adolescence male rats.

• The Journal of Pediatrics of Korean Medicine
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• v.17 no.2
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• pp.1-13
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• 2003

Objectives: The purpose of this study was to suggest a scientific method for measurement of children's growth development. Ultrasonic image of calcaneus bone has some advantages that it is harmless to human body and apply a new imaging analysis algorithm. it can be used for the diagnosis of growth analyzed the opening degree of growth plate and bone density. Methods: This clinical study have been carried out with the 57 case(male 24, female 33) of the children aged 5 to 14 years old who visited in Department of Pediatrics, Dongguk university Bundang Oriental Hospital. Bone maturity is measured by the opening degree of growth plate and bone density in ultrasonic image of calcaneus bone This study were designed to investigate the relationship of the development of children and the calcaneus bone maturity. Result: The opening degree of growth plate was no change in aged 5-10 years for male and 5-9 years for female but decreased significantly from aged 11 years for male and 10 years for female. the bone density was no change in aged 5-12 years for male and 5-11 years for female but increased significantly from aged 13 years for male and 12 years for female. it was confirmed that bone maturity in female is more rapid than in male. The opening degree of growth plate of claclneus bone was correlated with age, height, weight. The bone density was correlated with age, height, weight, BMI in this suudy(P<0.001) Conclusion: The opening degree of growth plate and bone density of calcaneus bone are sufficient diagnostic worth as an index to predict adolescent growth.

• Oral Biology Research
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• v.42 no.4
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• pp.222-227
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• 2018

The purpose of this study was to determine the cause and risk factors of removing bone plateby investigating and analyzing 359 patients who underwent reduction of fracture or orthognathic surgery with bone plate insertion over the past 3 years. Patients were evaluated with respect to age, smoking status, reason for insertion of plates, the numbers of inserted plates, sites of insertion, time between insertion and removal, reasons for removal of plates. The removal rate of bone plates was 33.1%. Of these, 17.0% of patients had clinical symptoms which led to remove plates. The removal rate of men was 29.9% and the rate of women was 39.2%. There were high removal rates from less than 20s (45.8%) and 20s (34.4%) those who are relatively young age group. On the other hand people in their 50s had a removal rate of 27.8% which was higher than those in their 60s with a rate of 20.7%. The removal rate of bone plate inserted into the mandible was 33.5%, and the removal rate of bone plate inserted into the maxilla was 34.7%. The mean period between the insertion and removal of bone plate was 10.9 months. The main reason for the removal of bone plate was the patient's requirement (44.5%). The most common cause of clinical symptoms was infection (22.7%). Infection was manifested within about a year and led to the plate being removed. Therefore, lowering the possibility of infection after surgery could decrease the removal rate of bone plate.

• Journal of Biomedical Engineering Research
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• v.16 no.1
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• pp.25-32
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• 1995

Clinically, proximal bone resorption in the femur is frequently seen postoperatively on the follow up XI-rays after total hip replacement (THR). We developed the finite element model of cementless THR. The model is two dimensional side plate model, whereby the three dimensional structural integrity of the bone can be accounted for by a separate two dimensional mesh, a side plate. The subject of this article is the development and application of this two dimensional side plate FEM to study the reverse effect of the various degree of bone resorption of femur after THR. The results of this study indicates that 1) two dimensional side plate model is good and simple alternative to complex three dimensional model and 2) the severity of the proximal bone resorption has the effect of more increasing stress on the cortex at the level of femoral stem tip.

• Proceedings of the KOSOMBE Conference
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• v.1994 no.12
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• pp.75-78
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• 1994

Clinically, proximal bone resorption in the femur is frequently seen postoperatively on the follow up X-rays after total hip replacement(THR). We developed the finite element model of cementless THR. The model is two dimensional side plate model, whereby the three dimensional structural integrity of the bone can be accounted for by a separate two dimensional mesh, a side plate. The subject of this article is the development and application of this two dimensional side plate FEM to study the reverse effect of the various degree of bone resorption of femur after THR. The results of this study indicates that two dimensional side plate model is good and simple alternative to complex three dimensional model and the severity of the proximal bone resorption has the effect of more increasing stress on the cortex at the level of femoral stem tip.

• The Journal of the Korean bone and joint tumor society
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• v.11 no.2
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• pp.175-182
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• 2005

Purpose: Bone tumor occurred in femur frequently involve proximal intertrochanteric region or distal metaphyseal region. Sometimes, the pathologic fracture can happen according to the size of tumor due to the substantial biomechanical stresses. Therefore, the prognosis can be improved biomechanically by the angled blade plate considering the anatomic configuration after the excision of tumor. Materials and Methods: Between October 1991 and April 2005, there were a total of 16 patients(17 cases) who were treated by the excision of tumor and internal fixation with the angled blade plate for bone tumor occurred in femur. After the excision of tumor, we filled the cavity by bone graft in 11 cases and bone cement in 6 cases. The internal fixation was used by angled blade plate in all cases. Result: The average follow-up time was 55.5 months(6-144 months) in 16 patients(17 cases). No metal failure occurred after the operation. Reoperation was performed in 4 cases due to tumor recurrence, and the internal fixation was firm until that. Conclusion: The angled blade plate can prevent the fracture until grafted bone incorporated to host bone, and protect fragile connection between cement and host bone.