The Korea Journal of Herbology (대한본초학회지)

The Korea Association of Herbology (대한본초학회)
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Effects of Cervi Pantotrichum Cornu and Cervi Cornu on Longitudinal Bone Growth in Adolescent Male Rats

녹용(鹿茸)과 녹각(鹿角)의 성장기 흰쥐 장골 길이성장에 대한 효과

  • Kim, Ki-Tae (Department of Herbology, College of Oriental Medicine, Semyung University) ;
  • Kim, Myung-Gyou (Department of Herbology, College of Oriental Medicine, Semyung University) ;
  • Leem, Kang-Hyun (Department of Herbology, College of Oriental Medicine, Semyung University)
  • 김기태 (세명대학교 한의과대학 본초학교실) ;
  • 김명규 (세명대학교 한의과대학 본초학교실) ;
  • 임강현 (세명대학교 한의과대학 본초학교실)
  • Published : 2006.03.30
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Abstract

Objectives : This study was designed to investigate the effects of Cervi Pantotrichum Cornu and Cervi Cornu on the growth of longitudinal bone in the adolescent male rats. Methods : Longitudinal bone growth was measured by fluorescence microscopy. To examine the effects on the growth plate metabolism, the heights of growth plate and the induction of local bone morphogenetic protein-2 were measured. Results : Treatment of Cervi Pantotrichum Cornu significantly enhanced longitudinal bone growth compared with control group. However, Cervi Cornu did not show the significant effects. Conclusion : Cervi Pantotrichum Cornu enhanced longitudinal bone growth and promoted the induction of local bone morphogenetic protein-2 of growth plate in adolescence male rats.

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