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The Antioxidation Effect of Salsola komarovii Extract and Its Influence on Cell Bio activity (수송나물(Salsola komarovii)의 항산화, 항염 및 미백 활성)

  • Kim, Min Jeong;Kim, Sook-Hee;Lee, Ja-Bok
    • Journal of Convergence for Information Technology
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    • v.10 no.10
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    • pp.308-317
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    • 2020
  • S. komarovii is halophyte that grows in soil or waters of high salinity, such as in saline semi-deserts, sloughs and seashores. Traditionally, S. komarovii has been used for food and medicinal purposes in Korea. S. komarovii was extracted in 70% ethanol to measure anti-oxidative activity using DPPH and ABTS assay. The IC50 values of the S. komarovii extract against DPPH radicals and ABTS radicals were 186.10 mg/mL and 121.89 mg/mL. In addition, total polyphenol and reducing power were measured. The S. komarovii extract exhibited superior polyphenolic (22.5%) and antioxidant (28.4%) contents. Regarding cell bioactivity, MTT assay was conducted to reveal cytotoxicity of S. komarovii extract and showed the non-cytotoxicity of S. komarovii extract. Anti-inflammatory and skin whitening effects were measured at 100 ㎍/mL. Therefore, this study suggests that the S. komarovii extract can be used as a functional cosmetic product material.

Lexical Access in the Bilinguals and the Category-specific Semantic System (이중언어의 어휘접근과 범주 특수적 의미체계)

  • Lee, Seung-Bok;Jung, Hyo-Sun;Jo, Seong-Woo
    • Korean Journal of Cognitive Science
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    • v.21 no.4
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    • pp.505-534
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    • 2010
  • The purpose of this study was aimed to compare the lexical access and representation of semantic system in the bilinguals. The participants(late Korean-English bilinguals) performed the word-picture matching task. The task was to decide whether the pictures presented after the words(basic-level categories) represent the Korean(L1) or English(L2) words' meaning or not. The stimuli were consisted of common object belonged to four different categories(animal, part of body, clothes, tool). To control the translation strategies, the SOA(stimulus onset asynchrony) were manipulated as 650ms(Exp. 1) and 200ms(Exp. 2). In both experiment, the RTs were faster in L1 condition. The decision time of the part of body categories were shorter than the animal in L1 condition. In L2 condition, clothes were responded faster than the tools. The differences of the lexical access time implied that the bilingual semantic system seemed to be structured by more sub-level categories than the super-level, living or non-living things, and the ways to access the bilingual lexicon might be differentiated according to the languages.

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Screening of Herbal Extracts to Reduce PAR-2 and Cytokine Expression Related to Atopic Dermatitis in Keratocytes (피부세포에서 아토피 피부염의 유발과 관련된 PAR-2 및 사이토카인의 발현을 감소시키는 한약재 탐색)

  • Park, Sun-Min;Lee, Jung-Bok;Kim, Da-Sol
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.25 no.2
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    • pp.270-274
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    • 2011
  • The prevalence of atopic dermatitis has markedly increased in recent years but the mechanism has not been clearly revealed. Recent study exhibited that atopic dermatitis was exacerbated by the increase of proteinase-activated receptor (PAR)-2 expression, which activated $I{\kappa}B$ kinase --> nuclear factor kappa B. Therefore, we determined whether the allergens of dust mites induced the expression of PAR-2, intercellular adhesion molecule-1 (ICAM-1, adehision molecule), interleukins (IL)-6 in HaCaT keratocytes and which herbal 1,3-butylene glycol extracts (Mori Cortex Radicis, Sanguisorba officinalis L., Arctium lappa Linne, Torilis japonica DC, Melia azedarach Linne var. japoinca Makino) suppressed their expression. Dust mite allergen increased PAR-2, ICAM-1 and IL-6 expression in HaCaT cells in a dose-dependent manner up to $3{\mu}g/mL$ but their expression reached the plateau over the dosages. The allergen ($3{\mu}g/mL$) also secreted more cytokines such as tumor necrosis factor (TNF)-${\alpha}$ and IL-6 into the media. Among five different herbal extracts ($50{\mu}g/mL$), Mori Cortex Radicis and Sanguisorba officinalis L. suppressed the PAR-2, ICAM-1 and IL-6 expression in HaCaT cells, which was activated by dust mite allergen ($3{\mu}g/mL$) and they also reduced the secretion of TNF-${\alpha}$ and IL-6 into the media. In conclusion, Mori Cortex Radicis and Sanguisorba officinalis L. can effectively reduce the prevalence and progression of atopic dermatitis by dute mite allergen.

The Improvement of the Korea Trade Finance Services (중소기업금융으로서 무역금융제도의 개선방안)

  • PARK, Kwang-So;HWANG, Ji-Hyeon;ZHOU, Ling-Ke
    • THE INTERNATIONAL COMMERCE & LAW REVIEW
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    • v.75
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    • pp.117-136
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    • 2017
  • Trade finance services have been played an important role in the Korea trade development history since 1960's. These days the trade environment is confronted by the 4th Industrial revolution and new trade protectionism. So we need to improve the Korea Trade Finance Services in order to improve Korea trade volume. Bank of Korea(BOK) also revised the Rule of Korea Trade Finance in 2014 and enlarged the trade fund for commercial banks where they handle the trade finance to small and medium enterprises(SME) in 2016. This article handle the current state and problems of Korea trade finance services and suggest the improvement measures as follows; First, the commercial banks, which handle trade finance fund, should improve the customs and practice of judge loan for SMEs. Second, the export volume counting rule for trade loan should harmonize between BOK's Rule and Foreign Trade Management Regulation under the Foreign Trade Act. Third, the processing trade and intermediate trade also can use the trade finance like other trade. Fourth, Trade finance should be in balance between export and import finance to defend the new protectionism. It means that the trade finance should expand to import in the certain conditions. Lastly, the related trade promotion agencies and their employees should improve their skills and abilities for handling trade finance.

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New Record of the Roundbelly Cowfish, Lactoria diaphana (Ostraciidae, Tetraodontiformes) from Korea (한국산 거북복과(Ostraciidae) 어류 1미기록종, Lactoria diaphana)

  • Kim, Byeong Yeob;Han, Song Hun;Song, Choon Bok
    • Korean Journal of Ichthyology
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    • v.28 no.4
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    • pp.279-282
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    • 2016
  • This is the first report of Lactoria diaphana (Tetraodontiformes: Ostraciide) from Korea. A single specimen (208.0 mm standard length) was collected off the coast of Jejudo Island by gill net on 14 November, 2011. This species is characterized by having a pair of strong spines in front of the eyes, a slightly curved spine on the dorsal ridge, a pair of strong and short spines on the ventro-lateral ridge and various-sized spots on the body. We add L. diaphana to the Korean fish fauna and propose a new Korean name, "So-ppul-bok" for the species.

Physiological Responses of Olive Flounder (Paralichthys olivaceus) by Capacity Density Difference during Salinity Change from Seawater to Freshwater (사육수의 담수화시 수용밀도에 따른 넙치(Paralichthys olivaceus)의 생리적 반응 비교)

  • Hur Jun Wook;Lee Bok Kyu;Min Byung Hwa;Park In-Seok;Choi Cheol Young;Lee Jeong Yeol;Chang Young Jin
    • Korean Journal of Environmental Biology
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    • v.22 no.3
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    • pp.419-425
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    • 2004
  • Two different groups (30 and 60 inds.) of olive flounder (Paralichthys olivaceus) were abruptly (within 30 min) exposed to hypo-salinities from seawater (SW, 35$\textperthousand$) to freshwater (FW, 0$\textperthousand$) (30FW and 60FW) and to 35$\textperthousand$ (30SW and 60SW) in a flow through seawater culture systems. Analysis of plasma samples showed the following significant increase at 0$\textperthousand$: cortisol from $2.8\;ng\;mL^{-1}$ to $66.9\;ng\;mL^{-1}$ (30FW) and from $2.7\;ng\;mL^{-1}$ to $314.1\;ng\;mL^{-1}$ (60FW) after 24 hours of exposure; glucose from $15.8\;mg\;dL^{-1}$ to $257.7\;mg\;dL^{-1}$ after 3 hours exposure and to $164.0\;mg\;dL^{-1}$ after 24 hours in 60FW. Plasma $Na^+$ concentration of 30FW and 60FW were decreased until 24 hours after expose. However that in 30SW and 60SW showed no significant differences. Plasma $Cl^-$ concentration of 60FW was decreased from $59.0\;mEq\;L^{-1}$ to $43.5\;mEq\;L^{-1}$ and to $30.0\;mEq\;L^{-1}$ after 3 and 24 hours of exposure, respectively. At all experimental groups, survival were 100% until 24 hours.

Nitrogen Removal by Electrochemical Oxidation Using the Tube Type Electrode (튜브형 전극을 이용한 전기화학적 산화에 의한 질소제거에 관한 연구)

  • Cho, Jae-Jun;Jeong, Jong-Sik;Lee, Jae-Bok
    • Journal of Korean Society of Water and Wastewater
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    • v.18 no.5
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    • pp.580-587
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    • 2004
  • The objective of this research is to investigate the electrochemical oxidation process for nitrogen removal in wastewater involving chloride ion and nitrogen compounds. The process experiment of electrochemical oxidation was conducted by using the stainless steel tube type reactor and the $Ti/IrO_2$ as anode. Free chlorine production and current efficiency variation for total nitrogen removal was compared depending on whether electrolyte is added, and the nitrogen type distribution under an operating condition. When chloride was added as electrolyte, it was found that production of free chlorine increased and the concentration of the chloride decreased as retention time passed. The concentration of chloride in influent decreased from 1,660 to 1,198 mg/L at the current density of $6.7A/dm^2$, while concentration of free chlorine increased to 132 mg/L. Current efficiency in removal of ammonium nitrogen was increased when chloride was dosed as electrolyte. It was observed that ammonium nitrogen was oxidized to nitrite and nitrate through electrochemical oxidation and that the concentration of total nitrogen in influent was reduced from 22.58 to 4.00 mg/L at the short retention time of 168 seconds through the electrochemical oxidation of nitrogen.

Temporal and Spatial Variations of the ML 5.8 Gyeongju Earthquake on September 12, 2016

  • Lee, Gyeong Su;Kyung, Jai Bok;Lee, Sang Jun
    • Journal of the Korean earth science society
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    • v.39 no.4
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    • pp.342-348
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    • 2018
  • An earthquake of $M_L$ 5.8 hit the Gyeongju area on September 12, 2016. A sequence of foreshock-mainshock-aftershock of 588 events with equal to or greater than magnitude 1.5 occurred for six months in this area. Around ninety-nine percentage (98.8%) of the total energy was released intensively within a day, and about 80% of the total events took place within a month after the Gyeongju earthquake. The epicentral distribution of aftershocks of major events ($M_L$ 5.1, 5.8, 4.5, and 3.5) were elongated in the direction of $N30^{\circ}E$. They correlate well with the focal mechanism solution. These facts support the inference that the Gyeongju earthquakes occurred on a sub-parallel subsidiary fault of the Yangsan fault zone or on the linking damage zones between Deokcheon and Yangsan fault. During the last six years before the Gyeongju earthquake, there were few events within 10-km radius from the epicenter. This seismic gap area was filled with a sequence of the Gyeongju earthquakes. The b value for aftershock of the Gyeongju earthquakes is 1.09.

Continuous Rapid Fermentation of Soy Sauce by Immobilized Zygosaccharomyces rouxii BH-90 and Candida versatilis BH-91 Using Column Type Reactor (고정화된 Zygosaccharomyces rouxii BH-90과 Candida versatilis BH-90를 이용한 Column 형 reactor 에서 간장의 연속적 속성발효)

  • Ryu, Beung-Ho;Cho, Kyung-Ja;Chae, Young-Ju;Jin, Seung-Heun
    • Microbiology and Biotechnology Letters
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    • v.21 no.4
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    • pp.366-372
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    • 1993
  • The aim of this study was to find out the rapid fermentation of soy sauce from koji hydrolyzate using column type reactor packed with immobilized yeast cells. Each immobilized cell of Zygosaccharomyces rouxii BH-90 and Candida versatilis BH-91 in the packed column type reactor produced 2.8% ethyl alcohol and 18mg/l 4-ethylguaiacol over 96 hours under the optimal condition. Continuous fermentation was performed by immobilized Z. rouxii BH-90 packed in column type reactor. Immobilized Z. rouxii BH-90 produced 2.30~2.85% ethyl alcohol during 30 days, and decreased gradually from 40 days to 80 days. Also C. versatilis BH-91 produced 4-ethylguaiacol at the constant rate of 16~18mg/l and decreased gradually after 40 days. Final product of soy sauce contained 2.8% ethyl alcohol and 18mg/l 4-ethylguaiacol. However, amino acid compositions of final products were consisted of predominantly glutamic acid, leucine, arginine, aspartic acid, lysine and valine, which were more than 50% of total amino acid.

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Controlled Release Properties of Ketoprofen from Methacrylate Polymer Gels (메타크릴레이트 폴리머로 제조한 겔 제제로부터 케토프로펜의 제어 방출특성)

  • Han, Kun;Park, Jeong-Sook;Kim, Nak-Seo;Chung, Youn-Bok;Cha, Cheol-Hee
    • Journal of Pharmaceutical Investigation
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    • v.21 no.1
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    • pp.1-10
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    • 1991
  • Hydrogels containing ketoprofen were prepared by adding NaOH or $Ca(OH)_2$ solution to Eudragit L, S and Eudispert hv at various concentration. And xerogels were prepared by drying hydrogels. On the other hand, organogels containing ketoprofen were prepared by mixing Eudragit L or S and propylene glycol. Effects of polymer content and base on drug release were investigated using KP V dissolution method. The release rate of ketoprofen from Eudragit L & S hydrogel decreased with increasing in polymer content. And the drug release rate from cal. hydroxide based gels were more decreased than that from sod. hydroxide based gels. At pH 7.2 dissolution medium, e release of ketoprofen from Edispert hv hydrogel followed apparent zero order kinetics. The release of ketoprofen from xerogel involved in simultaneous absorption of water and desorption of ketoprofen via a pH-dependant swelling controlled mechanism. The release of ketoprofen from Eudragit S organogels followed apparent zero order kinetics, providing strong evidence for a surface erosion mechanism.

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