• Biomolecules & Therapeutics
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• v.16 no.2
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• pp.141-146
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• 2008

Imbalance in calcium and phosphorous metabolism due to aging or menopause leads to osteoporosis. In contrast to patients with normal blood pressure, hypertensive patients have a higher loss of calcium in the urine with its attendant risk of osteoporosis. The high blood pressure is associated with the risk of bone loss and abnormalities in calcium metabolism leading to calcium loss. So we retrospectively investigated the changes of bone mineral density (BMD) which drugs can have clinical influences over osteoporosis treatments of patients with calcium-antagonists as common antihypertensive drugs and with bisphosphonates which causes a most effective inhibition of osteoclasts resorption. As a result over 70 years of age group and within bisphosphonates group, alendronate 70 mg once-weekly group showed significant increase of BMD in lumbar area. Combination group of cilnidipine and $maxmarvil^{(R)}$ showed very significant decrease of BMD. In conclusion, it is desirable that combination therapy with calcium-antagonists is used carefully in the treatment of osteoporosis with high blood pressure.

• Korean Journal of Clinical Laboratory Science
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• v.46 no.4
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• pp.143-149
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• 2014

Pulse wave velocity (PWV) is used to non-invasively estimate the severity of arteriosclerosis by measuring the patient's arterial stiffness comparing with each normal reference range according to their ages. Increased arterial stiffness is closely related to both atherosclerosis and arteriosclerosis, which have been known for causes of cardiovascular disease and stroke, also negatively affects the prognosis and the re-occurrence in patients with stroke. The study is focused on how brachial-ankle pulse wave velocity (baPWV) is related to cardiovascular disease risk factors in patients with acute stroke. There were 114 subjects, 69 males and 45 females, all in their 60's and had PWV test for acute stroke. The results are as follows: the group with increased arterial stiffness showed significant increase in HbAlc, total cholesterol, RSBP (resting systolic blood pressure), CSBP (central systolic blood pressure) and CDBP (central diastolic blood pressure). Cross tabulation test showed that there was a significant relationship only between the group with increased arterial stiffness and diabetes mellitus (DM). Therefore, it might be useful for preventing re-occurrence and making a favorable prognosis to promptly adjust DM and hypertension-related risk factors in patients with acute stroke.

• Research in Community and Public Health Nursing
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• v.17 no.4
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• pp.472-481
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• 2006

Purpose: Hypertension tends to increase after the age of 65. Proper hypertension management requires physical activities such as habitual activities and exercise. However. it is reported that many elders do not have regular physical activities. This study was to identify physical activity patterns and blood pressure according to physical activity in the elderly with hypertension. Methods: This study assessed physical activity frequency, amount, type during the latest one week, and blood pressure and BMI. The subjects were 53 elders aged over 65 years. Collected data were analyzed through descriptive statistics, $x^2-test$, and logistic regression analysis using SPSS 12.0. Results: It was found that most of the subjects had not been participating in regular physical activities. The most frequent physical activity patterns were walking and home activity at a low or moderate intensity. The elderly who met the normal hypertension and pre-hypertension criteria involved significantly more regular physical activities. Conclusion: This study suggested that regular participation in physical activities should be recommended for elders in order to optimize the state of their blood pressure.

• Journal of the Korea Society of Computer and Information
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• v.21 no.11
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• pp.113-120
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• 2016

The present study was conducted to assess gender differences in the relationship between adiposity and systolic inter-arm blood pressure difference (sIAD) in Korean adults. In this paper, we propose a 410 adults (235 men and 175 women) who were over 30 years old and had undergone a health check participated from June to November 2013. The incidences of high sIAD (sIAD ${\geq}10mmHg$) in males and females were 24.6% and 15.3%, respectively. We conducted a logistic regression analysis after adjusting for variables such as age, smoking, drinking, exercising, TC, TG, HDL-C, and FPG. Key study results were as follows: First, in men, the odds ratio (OR) of high sIAD of the obesity group was significantly higher than that of the normal weight group [2.25 (95% confidence interval (CI), 1.19-4.25)], but abdominal obesity was not associated with high sIAD. Second, in women, the OR of high sIAD of the abdominal obesity group was significantly higher than that of the non-abdominal obesity group [2.52 (95% CI, 1.03-6.13)], but obesity status was not associated with high sIAD. In conclusion, Obesity is associated with the incidence of high sIAD in Korean men, and abdominal obesity is associated with the incidence of high sIAD in Korean women.

• Physical Therapy Rehabilitation Science
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• v.2 no.1
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• pp.31-38
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• 2013

Objective: To determine the efficacy and reliability of measuring direct current microcurrent applied through the skin to determine injury in the underlying tissues. Design: Case control study. Methods: First, microcurrent was measured as decreased blood flow induced hypoxia in healthy subjects. Next, reliability was assessed by measuring over ten days with set variations in pressure and distance between the electrodes. Finally, measurements over sprained ankle were compared to measurements over comparable uninjured areas on the same injured subject. Results: For the blood flow test phase, microcurrent significantly decreased an average of 17% after 5 minutes (p<0.05), remained decreased for 30 seconds, and returned to non-occlusive levels after 2 minutes of normal circulation. The results indicate that the microcurrent decrease was not due to blood flow, and most likely from hypoxic cellular damage. For the reliability phase, the coefficients of variation averaged 10.3% for the shoulder, 14.8% for the low back, and 29.1% for the knee. Changing distance 2.5 cm between the electrodes resulted in insignificant changes. Changes in pressure had some significant effect after an increase in force of 2.6 N, affirming the need for consistent pressure for measurement. For the injury test phase, a significant 69% decrease occurred comparing injured areas to the same area on the uninjured side, and a significant 74% occurred comparing injured and non-injured areas on the same limb. Conclusions: Microcurrent through the skin shows promise as an objective method of assessing a soft tissue injury by detecting damage likely due to hypoxia.

• Journal of the Korea Safety Management & Science
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• v.23 no.3
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• pp.89-96
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• 2021

This study analyzed the physical changes in 119 paramedics transporting equipment at the emergency site and performing post-cardiopulmonary resuscitation through experiments. First, the average heart rate increased by about 25 times comparing CPR was performed without physical load and with personal protective equipment after moving equipment. In the third quartile, it increased to about 27 times. Second, when CPR was performed without physical load, and CPR was performed after moving the equipment with personal protective equipment, both the body temperature was raised and the rising body temperature was measured within normal body temperature. Third, the change in respiration rate increased by 7 times on average comparing CPR was performed without physical load and CPR was performed after moving the equipment while wearing personal protective equipment. In the third quartile, it increased to about 11 times. Finally, the change in blood pressure increased by 26.6 mmHg on average comparing CPR was performed without physical load and with wearing personal protective equipment after moving the equipment, and increased by 31.2 mmHg on average in the third quartile.

• Nutritional Sciences
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• v.8 no.1
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• pp.56-60
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• 2005

The aim of this study researchs status of the nutrient intake between male and female students and the nutrient intake by BMI. This study was done to investigate the body composition and nutrient intakes of 340 college students (170 males, 170 females) in Gyeonggi area. Weight, height, BMI, and blood pressure of these college students were measured Nutrient intake was assessed using the 24-hour recall method, and then calculated using the nutritional evaluation program [CAN Pro 2.0 professional (Korean Nutrition Society, 2002)]. Average height and weight were 176$\pm$5.1 cm, 70.60$\pm$l.l kg in male students and 162.2/$\pm$4.5 cm, 54.4$\pm$7.7 kg in female students respectively. Subjects were divided into three groups by BMI: underweight (less than 18.5), normal weight (18.5 to less than 23), and overweight (more than 23). The ratios of male and female subjects among these groups were 5.3% and 17.6% in underweight, 50% and 65.3% in normal weight, and 44.7% and 17.2% in overweight. Systolic and diastolic blood pressures were 124.0$\pm$1.5 mmHg and 76.1$\pm$14.8 mmHg in males and 1l0.l$\pm$12.9 mmHg and 70.l$\pm$10.8 mmHg in females, all in the normal range. Using nutrient values of the 7th Recommended Dietary Allowanes, the nutrient intake was calculated to Korean RDA (%). Nutrients below 75% Korean RDA were Calcium, Vitamin $B_2$, and Folate and nutrients above 100% RDA were Protein, Fe, Phosphorous, and Vitamin $B_6$. BMI showed positive correlations with body fat (%)(p<0.01) and WHR (p<0.01). Nutritional education is desirable for the improvement of dietary behaviors, body composition and nutrient intake of college students.

• Korean Journal of Community Nutrition
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• v.29 no.3
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• pp.212-221
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• 2024

Objectives: Metabolic disease is strongly associated with future insulin resistance, and its prevalence is increasing worldwide. Thus, identifying early biomarkers of metabolic-related disease based on serum profiling is useful to control future metabolic disease. Our study aimed to assess the association of serum branched chain amino acids (BCAAs) and aromatic amino acids (AAAs) ratio and metabolic disease according to body mass index (BMI) status among Korean adults. Methods: This cross-sectional study included 78 adults aged 20-59 years in Korea. We compared serum amino acid (AA) levels between adults with normal-weight and adults with obesity and investigated biomarkers of metabolic disease. We examined serum AA levels, blood profile, and body composition. We also evaluated the association between serum AAs and metabolic-related disease. Results: The height, weight, BMI, waist circumference, hip circumference, waist-hip-ratio, body fat mass, body fat percent, skeletal muscle mass, systolic blood pressure, and diastolic blood pressure were higher in the group with obesity compared to normal weight group. The group with obesity showed significantly higher levels of BCAA, AAA, and BCAA and AAA ratio. Further, BCAA and AAA ratio were significantly positively correlated with triglyceride, body weight, and skeletal muscle mass. The evaluation of metabolic disease risks revealed an association between the ratios of BCAAs and AAAs, hypertension, and metabolic syndrome. Conclusions: Our study is showed the associations between BCAA and AAA ratio, obesity, and obesity-related diseases using various analytical approaches. The elevated BCAA and AAA ratio could be early biomarkers for predicting future metabolic diseases in Korean population.

• Korean Journal of Community Nutrition
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• v.17 no.1
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• pp.49-68
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• 2012

The purpose of this study was to compare nutrient intakes, blood lipids and bone mineral density of male (n = 59) and female (n = 172) teachers according to the obesity index by percentage of body fat and age. The energy intakes of obesity group were higher than normal group in male (p < 0.05), but were not significant in female. The protein intake ratio among three energy nutrients for male was higher than female (p < 0.001), and lipid intake ratio of obesity group in female was a little higher than male that was not significant. TC, LDL, TC/HDL, risk of coronary heart disease, blood glucose and blood pressure of obesity group were higher than normal group in female (p < 0.01 ~ p < 0.001), but were little significance in male. Risk of coronary heart disease was affected by gender (p < 0.001), obesity degree (p < 0.01), age (p < 0.001), and interaction of gender and age (p < 0.001). Blood glucose was affected by obesity degree (p < 0.05), but was not affected by age. T-scores of forearm for female (= -1.42) were lower than that of male = -0.95), and T-scores of obesity group in male (= 0.12) were higher than that of normal group (= -0.33) but were not significant in female. The T-scores of forearm for female were affected by age (p < 0.05) and gender (p < 0.01), but calcaneus was not affected by gender. These results suggest lipid intake ratio should be balanced for obesity group in female. Nutritional education for treatment obesity to prevent hyperlipidemia and arteriosclerosis is necessary for obesity group and older age groups. T-scores of forearm were lower than calcaneus, so arm exercise would be especially required to prevent osteoporosis for older age women groups.

• The Korean Journal of Food And Nutrition
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• v.26 no.4
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• pp.975-984
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• 2013

This study is performed to estimate the prevalence of metabolic syndrome among male workers and to identify the relationships with many related factors including anthropometry, hematological index, serum lipid level, dietary-related behaviors and health-related behaviors. According to the age groups, the 20s are significantly higher in normal and risk groups than in the metabolic syndrome (MS) group, the 30s are significantly higher in MS group than the other groups. The levels of AST and ${\gamma}$-GTP both show significant differences in the order of MS group ($30.3{\pm}8.8U/l$, $91.1{\pm}40.2U/l$) > risk group ($25.7{\pm}8.1U/l$, $41.8{\pm}20.2U/l$) > normal group ($22.8{\pm}6.0U/l$, $26.6{\pm}10.7U/l$). For the frequency of breakfast consumption, the response of 'Every day' is significantly higher in MS group than normal and risk groups, but the response of 'Not at all' is significantly higher in normal group than MS and risk groups. The drinking amount is positively correlated with ${\gamma}$-GTP in normal group, and it is negatively correlated with the hematocrit level, but it is positively correlated with the systolic blood pressure in MS group. AST is positively correlated with glucose concentrations of the MS group. The ALT is positively correlated with waist circumferences and systolic blood pressure in the risk group. The results of this study show that breakfast frequency, education level, drinking amount, drinking frequency, exercise frequency, AST, ALT and ${\gamma}$-GTP levels are all important risk factors of MS. Therefore, it is very important to maintain a healthy life style for the prevention of MS incidence.