• Transactions on Electrical and Electronic Materials
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• 제9권1호
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• pp.38-43
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• 2008

Using an arterial pressure-volume (APV) model, we performed an analysis of the conventional blood pressure estimation method using an oscillometric sphygmomanometer with computer simulation. Traditionally, the maximum amplitude algorithm (MAA) has been applied to the oscillation waveforms of the APV model to obtain the mean arterial pressure and the characteristic ratio. The estimation of mean arterial pressure and characteristic ratio was significantly affected by the shape of the blood pressure waveforms and the cutoff frequency of high-pass filter (HPF) circuitry. Experimental errors result from these effects when estimating blood pressure. To determine an algorithm independent of the influence of waveform shapes and parameters of HPF, the volume oscillation of the APV model and the phase shift of the oscillation with fast Fourier transform (FFT) were tested while increasing the cuff pressure from 1 mmHg to 200 mmHg (1 mmHg/s). The phase shift between ranges of volume oscillation was then only observed between the systolic and the diastolic blood pressures. The same results were obtained from simulations performed on two different arterial blood pressure waveforms and one hyperthermia waveform.

• 여성건강간호학회지
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• 제14권1호
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• pp.28-35
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• 2008

Purpose: The study was performed to evaluate effects of aroma therapy on the anxiety, blood pressure and pulse of uterine leiomyoma patients before surgery and to apply it as the actual nursing intervention. Method: From Aug1st to Nov. 30th, 2007, the experimental group (n=30) and the control group (n=30) were selected in 1 hospital, Busan. Lavender and Bergamot oil mixed together at a 3:2 ratio was applied to the experimental group two times at 8-9 pm the day before surgery and twice 30 minutes before the surgery. Anxiety, VAS, blood pressure, and pulse were measured to evaluate the effects of aroma therapy. The data analysis was done using the SPSS/PC 12.0 program using chi-square test and t-test. Results: Hypothesis 1 was supported. The VAS of the experimental group was lower than control group after aroma therapy. Hypothesis 2 was partly supported. The systolic blood pressure and pulse of experimental group was significantly decreased, but diastolic blood pressure wasn't difference. The VAS, systolic blood pressure and pulse of control group were increased. Conclusion: The study verified that the aroma therapy is a very effective nursing intervention that can reduce anxiety before surgery. It is recommended to apply aroma therapy actively to patients experiencing anxiety before surgery procedure.

• 기본간호학회지
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• 제17권2호
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• pp.249-258
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• 2010

Purpose: To develop an e-learning blood-borne infection control program and to evaluate the effects of the program on risk perception, knowledge, preventive health behaviors related to blood-borne infections, and satisfaction with the program by nursing student. Methods: The program was developed through the processes of analysis, design, development, implementation, and evaluation. The pre-experimental research design involved a one group pretest-posttest design. The setting was two universities located in Daejeon, Korea. Results: Using the program that was designed and developed, results for the total score of risk perception, knowledge, and preventive health behaviors in the post-test application were significantly higher than in the pre-test application (p<.05). Relevance and usefulness of the information received the highest ratings, while the system's design were demonstrated to have the lowest ratings. Those areas requiring correction were modified accordingly. Conclusions: Application of an e-learning blood-borne infection control program is effective, and can be expanded to other student nurses who also have a high risk of blood-borne infections.

• 대한의생명과학회지
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• 제22권3호
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• pp.107-114
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• 2016

Maintenance of fasting blood glucose levels is important for glucose homeostasis. Disruption of feedback mechanisms are a major reason for elevations of glucose level in blood, which is a risk factor for type 2 diabetes mellitus that is mainly caused by malfunction of pancreatic beta-cell and insulin. The fasting blood glucose level has been known to be influenced by genetic and environmental factors. Mitochondria have many functions for cell survival and death: glucose metabolism, fatty acid oxidation, ATP generation, reactive oxygen species (ROS) metabolism, calcium handling, and apoptosis regulation. In addition to these functions, mitochondria change their morphology dynamically in response to multiple signals resulting in fusion and fission. In this study, we aimed to examine association between fasting blood glucose levels and variants of the genes that are reported to have functions in mitochondrial dynamics, fusion and fission, using a cohort study. A total 416 SNPs from 36 mitochondrial dynamics genes were selected to analyze the quantitative association with fasting glucose level. Among the 416 SNPs, 4 SNPs of PRKACB, 13 SNPs of PPP3CA, 6 SNPs of PARK2, and 3 SNPs of GDAP1 were significantly associated. In this study, we were able to confirm an association of mitochondrial dynamics genes with glucose levels. To our knowledge our study is the first to identify specific SNPs related to fasting blood glucose level.

• 대한의용생체공학회:학술대회논문집
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• 대한의용생체공학회 1993년도 추계학술대회
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• pp.51-54
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• 1993

The purpose of this research is to investigate the relationship between the blood flow and autonomic nervous system which regulates the circulation system. After the oral glucose tolerance test(GTT) the velocity changes of the blood flow were measured from the normal, hyperglycemia and diabetic neuropathy using the laser doppler. The FFT analyses showed that the spectrums were concentrated around the particular bands(0.02-0.166Hz, 0.8-1.1Hz) for the normal, while almost uniform distribution of the spectrums was observed for the abnormal. The blood glucose affects the compliance of the blood vessels and viscosity and finally causes the resistance problem in the blood vessels. An index PG was introduced, which was determined by the ratio of the change or the integral power spectrum in the range between 0.02 and 0.166Hz to change of the blood glucose before and after GTT. The index shows 1.0. 0.3 and 0.1 for the normal, hyperglycemia and diabetic neuropathy, respectively. As a conclusion, this spectrum analysis shows the potential of checking the progress or the diabetic, also car be used to evaluate the vasomotion which are regulated by the autonomic nervous system.

• 대한치과보존학회:학술대회논문집
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• 대한치과보존학회 2003년도 제120회 추계학술대회 제 5차 한ㆍ일 치과보존학회 공동학술대회
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• pp.546.1-546
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• 2003

Laser doppler flowmeter (LDF) has been applied to the measurement of pulpal blood flow (PBF) in human teeth. As far as we searched, the detection area of the pulp in the blood flow measurement has not been clarified, yet. Therefore, the purpose of this study was to obtain information of the detection area in PBF measurement using LDF. The experiments were performed on the artificial blood circulation in extracted human upper central incisors. The apical portions of examined teeth (n=6) were severed and root canals were enlarged from the apical end to the 2mm incisal to the level of enamel-cement junction. An individual resin cap of each tooth was prepared and a hole was drilled 2mm incisal to enamel-cement junction of the labial side of the cap. The measurement probe of LDF (MBF3D, Moor Instrument, UK) was plugged into the hole of the cap. Heparinized human peripheral blood, which was in advance collected and diluted 3 times with physiological saline, was pumped through the apical foramen of the teeth via a silicone tube and a disposable needle (o.d. 0.7mm) and blood flow signals were monitored. The flux signal significantly increased with the enlargement of the root canal to incisal direction (p<0.01, Friedman analysis). The result indicates that the performance of LDF in PBF with human teeth is limited.

• 한국학교ㆍ지역보건교육학회지
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• 제15권3호
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• pp.17-30
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• 2014

Objectives: The purpose of this study was to investigate the status of exposure to blood and body fluid and factors affecting on blood and body fluid exposure of nursing students including knowledge, performance regarding standard precautions. Methods: 280 nursing students in D-city and S-city participated in this study. Data collection was conducted from January to March 2012. Students' knowledge and performance on standard precautions of infection control in hospitals were measured using the measurement developed by Hong(2010). Data analysis was performed using descriptive statistics, t-test, one way-ANOVA, ${\chi}^2-test$, Pearson correlation coeficient, logistic regression by the SPSS WIN 18.0 program. Results: 58.6 percent of subjects experienced a exposure to blood and body fluid. The level of nursing students' knowledge level regarding standard precautions was $22.44{\pm}2.11$ and performance level was $4.31{\pm}0.50$. The factors affecting on blood and body fluid exposure of nursing students were knowledge level and education type about infection control. Conclusions: Based on the findings of this study, to decrease the exposure to blood and body fluid of nursing students, a proper education need to be stressed to improve nursing students' infection control knowledge and awareness.

• 한국가시화정보학회지
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• 제18권3호
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• pp.103-108
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• 2020

RBC (red blood cell) deformability is one of factors inducing blood shear thinning effect. Reduction of RBC deformability increases blood viscosity in high shear region. In this study, 3D printed chip with proper distribution of wall shear rate (WSR) was proposed to measure RBC deformability of blood samples. To fabricate 3D printed chip, the design of 3D printed chip determined through numerical simulation was modified based on the resolution of the 3D printer. For the estimation of pressure drop in the 3D printed chip, two bypass outlets with low and high WSR are exposed to atmospheric pressure through the needles. By positioning the outlet of needles in the gravity direction, the formation of droplets at bypass outlets can be captured by smartphone. Through image processing and fast Fourier transform (FFT) analysis, the frequency of droplet formation was analyzed. Since the frequency of droplet formation is related with the pressure at bypass, high pressure drop caused by reduction of RBC deformability can be estimated by monitoring the formation of blood droplets using the smartphone.

• Journal of Korean Neurosurgical Society
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• 제65권1호
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• pp.151-160
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• 2022

Continuous monitoring of intracranial pressure is a well established medical procedure. Still, little is known about long-term behavior of intracranial pressure in normal pressure hydrocephalus. The present study is designed to evaluate periodicity of intracranial pressure over long-time scales using intraventricular pressure monitoring in patients with normal pressure hydrocephalus. In addition, the circadian and diurnal patterns of blood pressure and body temperature in those patients are studied. Four patients, selected with "probable" normal pressure hydrocephalus, were monitored for several dozen hours. Intracranial pressure, blood pressure, and body temperature were recorded hourly. Autocorrelation functions were calculated and cross-correlation analysis were carried out to study all the time-series data. Autocorrelation results show that intracranial pressure, blood pressure, and body temperature values follow bimodal (positive and negative) curves over a day. The cross-correlation functions demonstrate causal relationships between intracranial pressure, blood pressure, and body temperature. The results show that long-term fluctuations in intracranial pressure exhibit cyclical patterns with periods of about 24 hours. Continuous intracranial pressure recording in "probable" normal pressure hydrocephalus patients reveals circadian fluctuations not related to the day and night cycle. These fluctuations are causally related to changes in blood pressure and body temperature. The present study reveals the complete loss of the diurnal blood pressure and body temperature rhythmicities in patients with "probable" normal pressure hydrocephalus.

• 한국보건간호학회지
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• 제23권2호
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• pp.285-295
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• 2009

Purpose: This study surveyed first-year college students on their knowledge of hypertension and their health behavior to obtain basic data necessary to develop hypertension prevention and management programs. Method: Subjects were 561 first-year students at a college in Chungcheongbuk-do, Korea. Data was collected using a structured questionnaire during the period from 01 October to 08 December 2007. Data analysis involved t-test, ANOVA, and Pearson correlation coefficient using SPSS for Windows. Results: Of the total subjects, 149 (26.6%) had a family history of hypertension 253 (45.1%) knew their blood pressure, 365 (65.9%) did not measure blood pressure, and 388 (69.1%) were not interested in knowing their blood pressure. Subjects' knowledge related to hypertension averaged 11.54 points out of 22, hypertension-related health behavior averaged 2.31 points out of 4. With a higher score indicative of increased attention paid to healthy behavior. Conclusion: Knowledge of blood pressure and characteristics of hypertension and management of both blood pressure and hypertension can be inadequate in first-year college students. Increased knowledge of hypertension may lead to better health behavior.