• Imaging Science in Dentistry
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• v.50 no.3
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• pp.217-226
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• 2020

Purpose: The purpose of this study was to analyze the quantity and quality of the mandibular anterior alveolar bone in terms of alveolar width, density, and total alveolar height (TAH) based on dental status, gender, and age. Additionally, this study aimed to quantitatively evaluate the available alveolar height for graft harvesting (AHGH) and examine its variability based on the aforementioned factors. Materials and Methods: This retrospective cone-beam computed tomographic study included a total of 100 subjects. On the basis of gender, dental status, and age, the scans were divided into 3 primary groups and 8 subgroups. The mandibular alveolar width and density were measured 5 mm mesial to the mental foramen bilaterally and at the midline. The TAH was measured at the midline, and the AHGH was measured as the midline distance between 5 mm apical to the root of the canines and 5 mm superior to the lower border. Results: The mandibular alveolar width was statistically similar between dentulous and edentulous patients (P>0.05). A significantly greater density was observed at the midline in edentulous patients (P<0.05). The TAH was significantly greater in edentulous male patients than in edentulous female patients (P<0.05). Dentulous and male patients had significantly greater AHGH than edentulous and female patients, respectively (P<0.05). Conclusion: Based on the data evaluated in this study, it can be concluded that the mandibular symphyseal area has adequate bone quality and quantity for bone graft harvesting for dental implant therapy.

• Journal of Advanced Marine Engineering and Technology
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• v.40 no.10
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• pp.906-915
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• 2016

In this study, a network monitoring system, including a secure 460-Network and a 460-Gateway, is designed and developed according with the requirements of the IEC (International Electro-Technical Commission) 61162-460 network standard for the safety and security of networks on board ships. At present, internal or external unauthorized access to or malicious attack on a ship's on board systems are possible threats to the safe operation of a ship's network. To secure the ship's network, a 460-Network was designed and implemented by using a 460-Switch, 460-Nodes, and a 460-Gateway that contains firewalls and a DMZ (Demilitarized Zone) with various application servers. In addition, a 460-firewall was used to block all traffic from unauthorized networks. 460-NMS (Network Monitoring System) is a network-monitoring software application that was developed by using an simple network management protocol (SNMP) SharpNet library with the .Net 4.5 framework and a backhand SQLite database management system, which is used to manage network information. 460-NMS receives network information from a 460-Switch by utilizing SNMP, SNMP Trap, and Syslog. 460-NMS monitors the 460-Network load, traffic flow, current network status, network failure, and unknown devices connected to the network. It notifies the network administrator via alarms, notifications, or warnings in case any network problem occurs. Once developed, 460-NMS was tested both in a laboratory environment and for a real ship network that had been installed by the manufacturer and was confirmed to comply with the IEC 61162-460 requirements. Network safety and security issues onboard ships could be solved by designing a secure 460-Network along with a 460-Gateway and by constantly monitoring the 460-Network according to the requirements of the IEC 61162-460 network standard.

• Membrane Journal
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• v.7 no.3
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• pp.131-135
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• 1997

Polymeric micellar enhanced ultrafiltration method using a new type of polyrmer, $\alpha$-allyl-$\omega$-methoxy polyoxyethlene and maleic anhydride copolymer (AKM-0531, Mw 15, 000), has been proposed to separate 1-naphthylamine as a weak cationic toxic organic solubilizate. Enhancement effect of polymeric micelle was identified by the ultrafiltration runs using polyacryronitrile(PAN) holow fiber membrane with molecular weight cut off 6, 000. The linear dependance of flux on the pressure difference is shown to be valid up to 0.6kg/${cm}^2$ and the rate of flux increase in response to change in the pressure is gradually reduced under the pressure difference. Rejection of 0.96 was observed for f mM of 1-naphthylamine with 2 wt.% polymer solution at the conditions of 0.4kg/${cm}^2$, natural pH. and $25^{\circ}C$ Solubilization of 1-naphthylamine into the polymeric micelle enhanced the separation efficiency.

• Conservation Science in Museum
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• v.18
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• pp.77-92
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• 2017

This study is based on a scientific analysis of the production method of the wooden seated Bodhisattva statue from Gwaneumsa Temple in Wando, which is currently housed at Chonnam National University Museum. The purpose was to investigate the characteristics of the statue's production through an X-ray inspection of the wooden timbers that make up its base material, a composition analysis of the surface layers, and microscopic observation. The votive prayers found together with the statue allowed the precise dating of the artifact to the sixteenth century, during the Joseon Dynasty. The X-ray transmission identified the statue as being made using the "ilmokjo"(一木造) technique, which means that the entirety of the statue excluding the right hand was produced using a single block of wood. The specimen analysis of the naturally exfoliated surface layer revealed that the current surface was coated with brass to restore the original gilt layer. These research findings added an interesting case to the existing related research and reaffirmed the academic value of this statue.

• Asian-Australasian Journal of Animal Sciences
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• v.32 no.12
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• pp.1864-1872
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• 2019

Objective: This study was conducted to evaluate the effects of Ecklonia stolonifera (E. stolonifera) extract addition on in vitro ruminal fermentation characteristics, methanogenesis and microbial populations. Methods: One cannulated Holstein cow ($450{\pm}30kg$) consuming timothy hay and a commercial concentrate (60:40, w/w) twice daily (09:00 and 17:00) at 2% of body weight with free access to water and mineral block were used as rumen fluid donors. In vitro fermentation experiment, with timothy hay as substrate, was conducted for up to 72 h, with E. stolonifera extract added to achieve final concentration 1%, 3%, and 5% on timothy hay basis. Results: Administration of E. stolonifera extract to a ruminant fluid-artificial saliva mixture in vitro increased the total gas production. Unexpectedly, E. stolonifera extracts appeared to increase both methane emissions and hydrogen production, which is contrasts with previous observations with brown algae extracts used under in vitro fermentation conditions. Interestingly, real-time polymerase chain reaction indicated that as compared with the untreated control the ciliate-associated methanogen and Fibrobacter succinogenes populations decreased, whereas the Ruminococcus flavefaciens population increased as a result of E. stolonifera extract supplementation. Conclusion: E. stolonifera showed no detrimental effect on rumen fermentation characteristics and microbial population. Through these results E. stolonifera has potential as a viable feed supplement to ruminants.

• Korean Journal of Metals and Materials
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• v.56 no.12
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• pp.910-914
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• 2018

Since catalyst technology is one of the promising technologies to improve the working performance of next generation energy and electronic devices, many efforts have been made to develop various catalysts with high efficiency at a low cost. However, there are remaining challenges to be resolved in order to use the suggested catalytic materials, such as platinum (Pt), gold (Au), and palladium (Pd), due to their poor cost-effectiveness for device applications. In this study, to overcome these challenges, we suggest a useful method to increase the surface area of a noble metal catalyst material, resulting in a reduction of the total amount of catalyst usage. By employing block copolymer (BCP) self-assembly and nano-transfer printing (n-TP) processes, we successfully fabricated sub-20 nm Pt line and cross-bar patterns. Furthermore, we obtained a highly ordered Pt cross-bar pattern on a Ni thin film and a Pt-embedded Ni thin film, which can be used as hetero hybrid alloy catalyst structure. For a detailed analysis of the hybrid catalytic material, we used scanning electron microscope (SEM), transmission electron microscope (TEM) and energy-dispersive X-ray spectroscopy (EDS), which revealed a well-defined nanoporous Pt nanostructure on the Ni thin film. Based on these results, we expect that the successful hybridization of various catalytic nanostructures can be extended to other material systems and devices in the near future.

• IMMUNE NETWORK
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• v.20 no.1
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• pp.10.1-10.14
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• 2020

Immune checkpoint inhibitors (ICIs) have shown remarkable benefit in the treatment of patients with non-small-cell lung cancer (NSCLC) and have emerged as an effective treatment option even in the first-line setting. ICIs can block inhibitory pathways that restrain the immune response against cancer, restoring and sustaining antitumor immunity. Currently, there are 4 PD-1/PD-L1 blocking agents available in clinics, and immunotherapy-based regimen alone or in combination with chemotherapy is now preferred option. Combination trials assessing combination of ICIs with chemotherapy, targeted therapy and other immunotherapy are ongoing. Controversies remain regarding the use of ICIs in targetable oncogene-addicted subpopulations, but their initial treatment recommendations remained unchanged, with specific tyrosine kinase inhibitors as the choice. For the majority of patients without targetable driver oncogenes, deciding between therapeutic options can be difficult due to lack of direct cross-comparison studies. There are continuous efforts to find predictive biomarkers to find those who respond better to ICIs. PD-L1 protein expressions by immunohistochemistry and tumor mutational burden have emerged as most well-validated biomarkers in multiple clinical trials. However, there still is a need to improve patient selection, and to establish the most effective concurrent or sequential combination therapies in different NSCLC clinical settings. In this review, we will introduce currently used ICIs in NSCLC and analyze most recent trials, and finally discuss how, when and for whom ICIs can be used to provide promising avenues for lung cancer treatment.

• Journal of Internet Computing and Services
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• v.15 no.3
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• pp.71-77
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• 2014

The equalization algorithm based on the cross-information potential concept and Dirac-delta functions (CIPD) has outstanding ISI elimination performance even under impulsive noise environments. The main drawback of the CIPD algorithm is a heavy computational burden caused by the use of a block processing method for its weight update process. In this paper, for the purpose of reducing the computational complexity, a new method of the gradient calculation is proposed that can replace the double summation with a single summation for the weight update of the CIPD algorithm. In the simulation results, the proposed method produces the same gradient learning curves as the CIPD algorithm. Even under strong impulsive noise, the proposed method yields the same results while having significantly reduced computational complexity regardless of the number of block data, to which that of the e conventional algorithm is proportional.

• Physical Therapy Rehabilitation Science
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• v.5 no.2
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• pp.89-94
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• 2016

Objective: This study was aimed to compare the thickness and pennation angle of gastrocnemius through ultrasonography during the heel-drop exercise on ankle dorsiflexion angle. Design: Cross-sectional study. Methods: Nineteen normal adults in their 20s had voluntarily participated in this study. All subjects performed the ankle heel-drop exercise with ankle dorsiflexed to $0^{\circ}$, $10^{\circ}$, and $20^{\circ}$: heel-drop exercise with ankle dorsiflexed to $0^{\circ}$ was executed on floor-level, heel-drop exercise with ankle dorsiflexed to $10^{\circ}$ on a wooden-block of 2.3 cm in height, and heel-drop exercise with ankle dorsiflexed to $20^{\circ}$ on a wooden-block of 5.5 cm in height. In each regimen, the subjects completed a session of 100 heel-drop exercises (10 repetitions${\times}$10 sets; with 30 seconds rest following each set; with 24 hours rest following each exercise). Before and immediately after each heel-drop exercise, the thickness and pennation angle of gastrocnemius were measured using an ultrasonography. Results: After the performance of the heel drop exercises with ankle dorsiflexed to $0^{\circ}$, $10^{\circ}$, and $20^{\circ}$, the thickness of the gastrocnemius was significantly higher than pre-exercise (p<0.05), and furthermore heel-drop exercise with ankle dorsiflexed to $10^{\circ}$ was significantly higher than exercise with the ankle dorsiflexed to $0^{\circ}$ (p<0.05). However, as for the pennation angle of the gastrocnemius, there were no significant changes after each heel-drop exercise. Conclusions: This finding suggest that the heel-drop exercise with ankle dorsiflexed to $0^{\circ}$, $10^{\circ}$, and $20^{\circ}$ is effective on the strengthening of the gastrocnemius. Furthermore, the heel-drop exercise with the ankle dorsiflexed to $10^{\circ}$ is more effective than with the ankle dorsiflexed to $0^{\circ}$.

• Journal of the Institute of Electronics and Information Engineers
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• v.51 no.8
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• pp.126-135
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• 2014

The Euclidean distance between error probability density functions (EDEP) has been used as a performance criterion for supervised adaptive signal processing in impulsive noise environments. One of the drawbacks of the EDEP algorithm is a heavy computational complexity due to the double summation operations at each iteration time. In this paper, a recursive method to reduce its computational burden in the estimation of the EDEP and its gradient is proposed. For the data block size N, the computational complexity for the estimation of the EDEP and its gradient can be reduced to O(N) by the proposed method, while the conventional estimation method has $O(N^2)$. In the performance test, the proposed EDEP and its gradient estimation yield the same estimation results in the steady state as the conventional block-processing method. The simulation results indicates that the proposed method can be effective in practical adaptive signal processing.