• Clinical and Experimental Pediatrics
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• 제59권4호
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• pp.165-173
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• 2016

Purpose: To identify the effects of modified parenteral nutrition (PN) and enteral nutrition (EN) regimens on the growth of very low birth weight (VLBW) infants. Methods: The study included VLBW infants weighing <1,500 g, admitted to Chungnam National University Hospital between October 2010 and April 2014, who were alive at the time of discharge. Subjects were divided according to 3 periods: period 1 (n=37); prior to the PN and EN regimen being modified, period 2 (n=50); following the PN-only regimen modification, period 3 (n=37); following both PN and EN regimen modification. The modified PN regimen provided 3 g/kg/day of protein and 1 g/kg/day of lipid on the first day of life. The modified EN regimen provided 3.5-4.5 g/kg/day of protein and 150 kcal/kg/day of energy. We investigated growth rate, anthropometric measurements at 40 weeks postconceptional age (PCA) and the incidence of extrauterine growth restriction (EUGR) at 40 weeks PCA. Results: Across the 3 periods, clinical characteristics, including gestational age, anthropometric measurements at birth, multiple births, sex, Apgar score, surfactant use and PDA treatment, were similar. Growth rates for weight and height, from time of full enteral feeding to 40 weeks PCA, were higher in period 3. Anthropometric measurements at 40 weeks PCA were greatest in period 3. Incidence of weight, height and head circumference EUGR at 40 weeks PCA decreased in period 3. Conclusion: Beginning PN earlier, with a greater supply of protein and energy during PN and EN, is advantageous for postnatal growth in VLBW infants.

• Journal of Preventive Medicine and Public Health
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• 제21권1호
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• pp.10-20
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• 1988

각 의료기관에서 분만하는 산모와 신생아의 특성을 비교분석하고 의료기관별 산모와 신생아의 위험수준을 조사하여 특정 의료기관에서 관찰한 연구결과를 해석하는데 참고 자료를 제공하기 위하여 대구시내 3개 대학병원, 2개 종합병원,2개 개인의원, 1개 조산소, 그리고 1개 모자보건센터에서 1987년 4월 1일 부터 4월 30일 까지 1개월간(1개 대학병원은 2개월간) 분만한 산모 1,410명을 대상으로 산모의 연령, 교육수준, 의료비 지불방법, 산과력 및 특정의료기관을 선택한 이유를 면담 조사하고 병원기록지에서 신생아의 출생시 체중의 조사하였다. 대학병원과 종합병원을 이용한 산모의 평균 연령은 각각 27.5세, 26.7세로 조산소(25.4세)와 모자보건센터(26.1세)를 이용한 산모보다 많았고, 교육수준은 대학병원(평균 12.7년)과 종합병원(평균 12.2년) 산모가 조산소(평균 9.2년) 및 모자보건센터(평균 9.3년) 산모보다 월등히 높았다. 그리고 의료보험 대상자도 대학병원(78.1%)과 종합병원(82.9%) 산모가 개인의원(44.3%), 조산소(29.1%)나 모자보건센터(5.4%) 보다 많았다. 모자보건센터는 2번째 출산이 47.3%로 가장 많았으나 다른 의료기관은 모두 초산부가 $56.0{\sim}61.7%$로 제일 많았다. 산모의 산과력 비교에서는 대학병원 산모가 자연유산 경험율이 상대적으로 다른 의료기관 산모보다 높았고 사산 경험자도 소수였으나 조산소와 모자보건센터에서 분만한 산모는 사산 경험자가 1명도 없었다. 대학병원 산모의 경우 37주 이하의 조산아 출생율(11.4%)과 2,499gm이하의 저체중아 출생율($5.8{\sim}13.0%$)은 타 의료기관 보다 현저히 높았다. 이에 따라 제왕절개술에 의한 분만율은 의료기관간에 차이가 많았다. 결국 대구시내 대학병원과 종합병원에서 분만하는 산모들은 사회경제적으로 중, 상류층과 소득고하를 막론하고 고위험산모들이 많고 조산소와 모자보건센터는 저소득충의 산모 가운데 산과적으로 저위험군들이 많이 이용하고 있다. 따라서 특정 의료기관을 대상으로 조사한 자료를 해석하는데 많은 제한성이 있으며 전체 산모의 특성으로 일반화하는 것은 불가능한 것으로 생각된다.

• 가정과삶의질연구
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• 제26권1호
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• pp.51-67
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• 2008

The study analyzes divorce rates in Korea and makes suggestions for the future research of divorce rates. Based on the data from Korea Statistical Information System (KOSIS) of the National Statistics Organization, trends for divorce rates change and the relations between divorce rates and macro environmental factors are analyzed. Macro environmental factors include socioeconomic factors such as, Korean War, Vietnam War, oil shock, IMP economic crisis and gross national income (GNI), whereas demographical factors include population structure, rates of female labor participation, and geographical location. The principle characteristics of divorce rates are as follows: 1) the Crude divorce rates (CDR) and the number of divorced had been increased from 1970 to 2004, then the trend changed to a decrease; 2) the slope of the change were the highest during 1998 to 2004 after the IMP economic crisis. The relations between socioeconomic factors are as follows: 1) during the war there was a small increase of CDR for a short period of time; 2) the economic crisis of the nation tend to increase the CDR, while the IMP economic crisis had a strong impact on an increase of CDR because of the interaction effect among the population structure, women's sex role changes as well as the level of standard of living. The increase in CDR from 1990 to 2000 can be explained partly by the population of baby Boomers passing through their marriage and divorce process. The number of population residing in the rural area and the middle class households, and the mobility of population also had an impact on the divorce rates changes. The recommendations for the future research were as follows: 1) the need to develop new divorce statistics that are based on a marriage cohort or a birth cohort because family behavior is a mixture of personal, social and political responses, and because CDR is not an accurate measure of divorce rate since it was influenced by population structure; 2) the need to include micro personal factors as well as macro social factors in a model to find an interaction effect between those variables.

• Clinical and Experimental Pediatrics
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• 제50권12호
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• pp.1206-1211
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• 2007

목 적 : 사회경제적 환경의 변화로 첫 아이를 출산하는 어머니의 연령이 늦어지고 있다. 많은 연구자들이 첫 아이를 출산하는 어머니의 연령이 늦어지는 것과 저체중출생아의 출생율과의 관계에 대해 연구하였으나 아직 일치된 연구결과를 얻지 못하고 있다. 이에 따라 본 연구자들은 산모의 연령이 저체중출생아의 출생률에 미치는 영향을 알아보고자 본 연구를 시행하였다. 방 법 : 2001년부터 2003년까지 통계청의 인구동태자료 중 출생기록에 등록된 1,545,338명 중 단태아면서 첫 번째 아이인 736,167명을 대상으로 저체중출생아와 극소저체중출생아의 출생률에 대해 어머니의 나이, 직업, 학력, 결혼유무, 거주지, 결혼 기간, 아버지의 직업과의 관계를 다중 로지스틱 회귀분석을 이용하여 분석하였다. 결 과 : 산모의 연령에 따라 저체중출생아가 출생할 위험률은 30-34세, 35-40세, 40세 이상의 초산부는 25세에서 29세의 초산부에 비해 각각 1.3배, 2.1배, 2.4배 높게 나타났으며 어머니의 직업, 학력, 결혼유무, 거주지, 결혼 기간, 아버지의 직업 등을 감안하여도 1.3배, 1.9배, 2.0배로 모두 유의하게 높게 나타났다. 산모의 연령에 따라 극소체중출생아가 출생할 위험률은 30-34세, 40-44세, 45세 이상의 초산부는 25세에서 29세의 초산부에 비해 각각 1.8배, 3.3배, 3.7배 높게 나타났으며 어머니의 직업, 학력, 결혼유무, 거주지, 결혼 기간, 아버지의 직업 등을 보정하여도 1.6배, 2.7배, 2.6배로 모두 유의하게 높게 나타났다. 각각의 산모의 연령과 교육 정도, 결혼유무에 따른 저체중출생아의 출생률을 비교하였을 때 30대의 고등학교 졸업 이상이고 기혼인 산모에서 저체중출생아의 출생률(3.7%)은 20대의 고등학교 졸업이상이고 기혼인 산모보다 더 낮았다. 결 론 : 본 연구에서 산모가 나이가 많아질수록 저체중출생아와 극소저체중출생아가 출생할 위험률이 높으며 어머니의 직업, 학력, 결혼유무, 거주지, 결혼 기간, 아버지의 직업 등을 고려하여도 높다. 하지만 나이가 많은 산모라도 사회경제적 환경이 개선된 다면 저체중출생아의 출생률을 줄일 수 있고 사료된다.

• Clinical and Experimental Reproductive Medicine
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• 제29권2호
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• pp.77-82
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• 2002

Objective : This study is to evaluate the efficacy of intracytoplasmic sperm injection (ICSI) for previous fertilization failure with conventional in vitro fetrtilization (IVF), compared with ICSI for male factor. Method: The author analyzed the 3 years of clinical experience with ICSI retrospectively, between the conventional IVF failure group (IVF failure) and male factor group (male factor). Surgically retrieved epididymal or testicular spermatozoa for ICSI were excluded. The IVF failure group was 13 cycles of 6 patients and male factor group was 30 cycles of 15 patients. Results: The fertilization rates of the IVF failure group and male factor group were 63% and 66% respectively (p=0.635). The clinical pregnancy rates of the both group were 23.1% and 26.7% (p=0.804), and that of live birth rates were 15.4% and 13.3% (p=0.858). There were no significant difference between the two groups. Conclusion: The author concluded that ICSI can overcome previous fertilization failure, with the same fertilization and clinical pregnancy rates seen in patients with male factor.

• 여성건강간호학회지
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• 제18권2호
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• pp.98-107
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• 2012

Purpose: This study was done to identify the effects of self-breast pumping on breastfeeding rates and, the degree of breast milk fullness among primiparous women giving birth by cesarean section. Methods: The study design was a non-synchronized posttest control group experiment with repeated measures. The participants were 60 women, 31 in the experimental group who used a manual pump 5 times a day after exclusive breastfeeding and 29 in the control group who breastfed exclusively with no other interventions. Results: While self-breast pumping did not improve breastfeeding rates or the degree of breast milk fullness at any of the time points studied, breastfeeding rates continued to remain high till 12 weeks postpartum in both groups. Conclusion: Although some modifications in research methods will be required to identify the effects of breast pumping and exclusive breastfeeding, both these approaches can be used as interventions to improve breastfeeding rates and breast milk quantity.

• 한국동물번식학회:학술대회논문집
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• 한국동물번식학회 2004년도 춘계학술발표대회
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• pp.247-247
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• 2004

수정란 이식의 효율 증진을 위해서는 수태율의 증진 성공적 분만과 송아지 육성에 있다. 수태율의 증진을 위해서는 사양관리가 양호하고 번식기능이 좋은 수란우의 선발, 임신에 적합한 양질의 수정란, 수란우와 수정란의 동기화 정도와 이식 시술자의 기술력 등이 잘 조화를 이루는 것이 절대적으로 필요하다. 적절한 수란우의 선발과 양질의 수정란을 수정란 이식에 적용하는 것은 수정란 이식의 산업화를 더욱더 촉진할 것으로 생각된다. (중략)

• 대한예방의학회:학술대회논문집
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• 대한예방의학회 2004년도 제56차 추계 학술대회 연제집
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• pp.81.1-81.1
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• 2004

• Asian Pacific Journal of Cancer Prevention
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• 제17권1호
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• pp.381-386
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• 2016

Background: Bladder cancer is an international public health problem. It is the ninth most common cancer and the fourteenth leading cause of death due to cancer worldwide. Given aging populations, the incidence of this cancer is rising. Information on the incidence and mortality of the disease, and their relationship with level of economic development is essential for better planning. The aim of the study was to investigate bladder cancer incidence and mortality rates, and their relationship with the the Human Development Index (HDI) in the world. Materials and Methods: Data were obtained from incidence and mortality rates presented by GLOBOCAN in 2012. Data on HDI and its components were extracted from the global bank site. The number and standardized incidence and mortality rates were reported by regions and the distribution of the disease were drawn in the world. For data analysis, the relationship between incidence and death rates, and HDI and its components was measured using correlation coefficients and SPSS software. The level of significance was set at 0.05. Results: In 2012, 429,793 bladder cancer cases and 165,084 bladder death cases occurred in the world. Five countries that had the highest age-standardized incidence were Belgium 17.5 per 100,000, Lebanon 16.6/100,000, Malta 15.8/100,000, Turkey 15.2/100,000, and Denmark 14.4/100,000. Five countries that had the highest age-standardized death rates were Turkey 6.6 per 100,000, Egypt 6.5/100,000, Iraq 6.3/100,000, Lebanon 6.3/100,000, and Mali 5.2/100,000. There was a positive linear relationship between the standardized incidence rate and HDI (r=0.653, P<0.001), so that there was a positive correlation between the standardized incidence rate with life expectancy at birth, average years of schooling, and the level of income per person of population. A positive linear relationship was also noted between the standardized mortality rate and HDI (r=0.308, P<0.001). There was a positive correlation between the standardized mortality rate with life expectancy at birth, average years of schooling, and the level of income per person of population. Conclusions: The incidence of bladder cancer in developed countries and parts of Africa was higher, while the highest mortality rate was observed in the countries of North Africa and the Middle East. The program for better treatment in developing countries to reduce mortality from the cancer and more detaiuled studies on the etiology of are essential.

• Journal of Preventive Medicine and Public Health
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• 제49권3호
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• pp.165-175
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• 2016

Objectives: The present study was undertaken to study the maternal risk factors for preterm birth (PTB) and low birth weight (LBW) with a special emphasis on assessing the proportions of maternal genitourinary and periodontal infections among Indian women and their association with adverse pregnancy outcomes. Methods: A hospital-based prospective study comprising 790 pregnant women visiting the obstetrics clinic for a routine antenatal check-up was undertaken. Once recruited, all study participants underwent clinical and microbiological investigations for genitourinary infections followed by a dental check-up for the presence of periodontitis. The study participants were followed up until their delivery to record the pregnancy outcomes. Infectious and non-infectious risk factors for PTB and LBW were assessed using univariate and multivariate Cox regression analysis. Independent risk factors for PTB and LBW were reported in terms of adjusted relative risk (ARR) with the 95% confidence interval (CI). Results: Rates of PTB and LBW in the study population were 7.6% and 11.4%, respectively. Previous preterm delivery (ARR, 5.37; 95% CI, 1.5 to 19.1), periodontitis (ARR, 2.39; 95% CI, 1.1 to 4.9), Oligohydramnios (ARR, 5.23; 95% CI, 2.4 to 11.5), presence of Nugent's intermediate vaginal flora (ARR, 2.75; 95% CI, 1.4 to 5.1), gestational diabetes mellitus (ARR, 2.91; 95% CI, 1.0 to 8.3), and maternal height <1.50 m (ARR, 2.21; 95% CI, 1.1 to 4.1) were risk factors for PTB, while periodontitis (ARR, 3.38; 95% CI, 1.6 to 6.9), gestational hypertension (ARR, 3.70; 95% CI, 1.3 to 10.8), maternal height <1.50 m (ARR, 2.66; 95% CI, 1.3 to 5.1) and genital infection during later stages of pregnancy (ARR, 2.79; 95% CI, 1.2 to 6.1) were independent risk factors for LBW. Conclusions: Our study findings underscore the need to consider screening for potential genitourinary and periodontal infections during routine antenatal care in developing countries.