• Communications for Statistical Applications and Methods
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• v.16 no.2
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• pp.373-381
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• 2009

Evidence of linkage is expressed as a decreasing trend of the squared trait difference of two siblings with increasing identical by descent scores. In contrast to successes in the application of a parametric approach of Haseman-Elston regression, notably low powers are demonstrated in the nonparametric linkage analysis methods for complex traits and diseases with sib-pairs data. We report that the Genehunter nonparametric linkage statistic is biased and furthermore the variance formula that they used is an inflated one, and this is one reason for a low performance. Thus, we propose bias-corrected nonparametric linkage statistics. Simulation studies comparing our proposed nonparametric test statistics versus the existing test statistics suggest that the bias-corrected new nonparametric test statistics are more powerful and attains efficiencies close to that of Haseman-Elston regression.

• Communications for Statistical Applications and Methods
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• v.16 no.5
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• pp.851-858
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• 2009

In the last decades, there has been much interest in climate variability because its change has dramatic effects on humanity. Especially, the precipitation data are measured over space and their spatial association is so complicated. So we should take into account such a spatial dependency structure while analyzing the data. However, in linear models for analyzing the data, data sets show severely skewed distribution. In the paper, we consider the Box-Cox transformation to satisfy the normal distribution prior to the analysis, and employ a Bayesian hierarchical framework to investigate the spatial patterns. The data set we considered is monthly average precipitation of the third quarter of 2007 obtained from 347 automated monitoring stations in Contiguous South Korea.

• Journal of the Korean Data and Information Science Society
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• v.24 no.6
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• pp.1401-1408
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• 2013

Kim and Kim (1992) proposed typical nonparametric method for umbrella alternative in randomized block design with replications. In this paper, We consider a test procedure for umbrella alternatives in a randomized block design using extension of the two sample placement tests described in Orban and Wolfe (1982) and treatment tests described in Kim (1999). We perform a Monte Carlo study to compare the empirical powers of the test statistics for underlying distributions.

• Communications for Statistical Applications and Methods
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• v.19 no.6
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• pp.781-791
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• 2012

A $2{\times}2$ Cross-over design is widely used in clinical trials for comparison studies of two kinds of drugs or medical treatments. This design has many statistical methods such as Hills-Armitage's (1979) method or Koch's (1972) method. In this paper, we propose a nonparametric test for $2{\times}2$ Cross-over design based on a two-sample test suggested by Baumgartner et al. (1998). In addition, a Monte Carlo simulation study is adapted to compare the power of the proposed methods with those of previous methods.

• Communications for Statistical Applications and Methods
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• v.18 no.2
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• pp.179-187
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• 2011

The purpose of a Phase I clinical trial is to estimate the maximum tolerated dose, MTD, of a new drug. In this paper, the MTD estimation method is suggested by curve fitting the dose-toxicity data to an S-shaped curve. The suggested MTD estimation method is compared with established MTD estimation procedures using a Monte Carlo simulation study.

• Communications for Statistical Applications and Methods
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• v.14 no.3
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• pp.609-621
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• 2007

Diagnostic test results, which are approximately normal with a few number of outliers, but non-normal probability distribution, are frequently observed in practice. In the evaluation of two diagnostic tests, Greenhouse and Mantel (1950) proposed a parametric test under the assumption of normality but this test is inappropriate for the above non-normal case. In this paper, we propose a computationally simple nonparametric test that is based on quantile estimators of mean and standard deviation, instead of the moment-based mean and standard deviation as in some parametric tests. Parametric and nonparametric tests are compared with simulations under the assumption of, respectively, normality and non-normality, and under various combinations of the probability distributions for the normal and diseased groups.

• Communications for Statistical Applications and Methods
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• v.16 no.1
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• pp.75-83
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• 2009

Parallelism tests are proposed for slope in the simple linear regression models. In this paper, we suggest the parametric test using HSD testing method (Tukey,1953) and distribution-free test using Kruskal-wallis (1952) for more than three slopes. Monte Carlo simulation study is adapted to compare the power of the proposed methods with Wilks' Lambda multivariate procedure.

• International Journal of Reliability and Applications
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• v.8 no.1
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• pp.67-82
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• 2007

This paper deals with the effectiveness analysis of an engineering system, which has two units of different strengths in parallel and one unit as a cold standby unit. Failure times for all the units have negative exponential distribution whereas their repair times have general distribution. Single server caters the need for the system. The effectiveness analysis of the system is done by using regenerative point technique. The different measures of effectiveness such as mean sojourn time, mean time to system failure, availability, busy period, etc, are derived. Cost factors also taken into consideration.

• Journal of applied mathematics & informatics
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• v.9 no.1
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• pp.185-195
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• 2002

Previous research has shown that the flow of patients around departments of geriatric medicine and ex-patients in the community may be-modelled by the application of a mixed-exponential distribution. In this proper we considered a ave-compartment model using a continuous-time Markov process to describe the flow of patients. Using a M/ph/c queuing model, we present a way of optimizing the number of beds in order to maintain an acceptable delay probability a sufficiently low level. Finally, we constructed a Java computer simulation, using data from St George's Hospital, London.

• Journal of the Korean Data and Information Science Society
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• v.22 no.6
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• pp.1105-1112
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• 2011

Mack (1981), Skilling and Wolfe (1977, 1978) proposed typical nonparametric method in randomized block design with replications. In this paper, we proposed the procedures based on placement as extension of the two sample placement tests described in Orban and Wolfe (1982) and treatment versus control tests described in Kim (1999). Also Monte Carlo simulation study is adapted to compare power of the proposed procedure with those of previous procedures.