• Journal of Computing Science and Engineering
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• 제10권1호
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• pp.21-31
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• 2016

With the application and development of biomedical techniques such as next-generation sequencing, mass spectrometry, and medical imaging, the amount of biomedical data have been growing explosively. In terms of processing such data, we face the problems surrounding big data, highly intensive computation, and high dimensionality data. Fortunately, cloud computing represents significant advantages of resource allocation, data storage, computation, and sharing and offers a solution to solve big data problems of biomedical research. In order to improve the efficiency of resource management in cloud computing, this paper proposes a clustering method and adopts Radial Basis Function in order to compress comprehensive data sets found in biology and medicine in high quality, and stores these data with resource management in cloud computing. Experiments have validated that with such a data-compression-based resource management in cloud computing, one can store large data sets from biology and medicine in fewer capacities. Furthermore, with reverse operation of the Radial Basis Function, these compressed data can be reconstructed with high accuracy.

• Journal of Genetic Medicine
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• 제10권1호
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• pp.27-32
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• 2013

Post-transcriptional nucleotide sequence modification of transcripts by RNA editing is an important molecular mechanism in the regulation of protein function and is associated with a variety of human disease phenotypes. Identification of RNA editing sites is the basic step for studying RNA editing. Databases and bioinformatics resources are used to annotate and evaluate as well as identify RNA editing sites. No method is free of limitations. Correctly establishing an analytic pipeline and strategic application of both experimental and bioinformatics methods constitute the first step in investigating RNA editing. This review summarizes modern bioinformatics approaches and related resources for RNA editing research.

• Proceedings of the KIEE Conference
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• 대한전기학회 2015년도 제46회 하계학술대회
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• pp.1431-1432
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• 2015

A system was developed to continuously monitor the respiratory signal under critical care, followed by performance evaluation for clinical application. Very much accurate pressure measurement was made in the endo-tracheal tube with mean relative error of 0.13%. In the comparative experiment simulating inspiration and expiration, the tidal volume measurement was also accurate within mean relative error of 3%, validating reliable measurement of respiratory signals.

• Proceedings of the KOSOMBE Conference
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• 대한의용생체공학회 1997년도 추계학술대회
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• pp.497-500
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• 1997

In this paper, we proposes a bending actuator using shape memory alloy coil-type springs. By the heating of two shape memory alloy coil-type springs sequentially, the bending and stretching motion of the actuator is possible. We measure the bending angle and repeated bending motion with the various currents. Furthermore, we control the bending angle of the 1 directional bending actuator with sensors. The performance of the actuator has been characterized or the possible application for catheter.

• Proceedings of the Korean Powder Metallurgy Institute Conference
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• 한국분말야금학회 2006년도 Extended Abstracts of 2006 POWDER METALLURGY World Congress Part 1
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• pp.248-249
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• 2006

Direct Metal Laser Sintering (DMLS) has been utilized for prototype manufacturing of functional metal components for years now. During this period the surface quality, mechanical properties, detail resolution and easiness of the process have been improved to the level suitable for direct production of complex metallic components for various applications. The paper will present the latest DMLS technology utilizing EOSINT M270 laser sintering machine and EOSTYLE support generation software for direct and rapid production of complex shaped metallic components for various purposes. The focus of the presentation will be in rapid manufacturing of customized biomedical implants and surgical devices of the latest stainless steel, titanium and cobalt-chromium-molybdenum alloys. In addition to biomedical applications, other application areas where complex metallic parts with stringent requirements are being needed will be presented.

• Proceedings of the KOSOMBE Conference
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• 대한의용생체공학회 1996년도 추계학술대회
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• pp.335-336
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• 1996

Flexible, self-expanding metallic stent were developed using igzag wire bend and segmented polyurethane. Mechanical properties of these stents were tested using INSTRON. These stents were used for palliative treatment of mallignant esophagogastric strictures(3 case) and bawl preparation of collorectal obstruction(10 case). All stents were inserted with fluoroscopic guidance without techinal failures. According to the results, these stents are easy to insert, safe, and very effective for dilation of strictures in curved GI tract.

• Proceedings of the KIEE Conference
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• 대한전기학회 2007년도 제38회 하계학술대회
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• pp.1918-1919
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• 2007

In this study, dynamic time warping(DTW) is utilized especially for automatically segmenting ECG(Electrocardiogram) signal to extract a periodic time information. For the possible medical application for diagnosing the abnormalities of ECG, the relative metric distance of the warped ECG signals are computed to decide whether the abrupt variations of ECG signal occur or not.

• 제어로봇시스템학회:학술대회논문집
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• 제어로봇시스템학회 1995년도 Proceedings of the Korea Automation Control Conference, 10th (KACC); Seoul, Korea; 23-25 Oct. 1995
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• pp.500-504
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• 1995

A neural network based upon the back propagation algorithm was designed and applied to acoustic power spectra of electrohydraulic total artificial hearts in order to diagnose mechanical failure of devices. The trained network distinguished spectra of the mechanically damaged device from those of the undamaged device with overall success rate of 63%. Moreover, the network correctly classified more than 70% of spectra in the frequency bands of 0-100 Hz and 700-950 Hz. Consequently, the neural network analysis was useful for the diagnosis of mechanical failure of a total artificial heart.

• Proceedings of the Korean Society of Toxicology Conference
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• 한국독성학회 2003년도 추계학술대회
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• pp.163-163
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• 2003

Difficulties of long-tenn survival of lung cancer patients treated with conventional therapies require the need for novel approaches and gene therapy holds promise in this area. Several genes are known to have anti-tumor activities and have been used as a gene of delivery, however, a number of problems such as efficiency, specificity of the gene delivery hinder the application of gene therapy.(omitted)

• Journal of the Korean Institute of Electrical and Electronic Material Engineers
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• 제23권9호
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• pp.724-729
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• 2010

We have proposed a new configuration on the cathode structure to improve a neutron yield without the application of external ion sources in an inertial electrostatic confinement (IEC) device. A neutron yield in the IEC device is closely related to the potential well structure generated inside the cathode and is proportional to the ion current. Therefore, the application of a double grid cathode structure to the IEC device is expected to produce a higher ion current and neutron yield than at a single grid cathode due to a high electric field strength generated around the cathode. These possibilities were verified as compared with the ion current calculated from both shape of the single and double grid cathode. Additionally from the results of ion's lives and trajectories examined at various outer cathode voltages and grid cathode configurations by using particle simulations, the validity of the double grid cathode was confirmed.