• Proceedings of the KOSOMBE Conference
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• v.1992 no.05
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• pp.184-185
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• 1992

This paper investigates the EEG waveform distortions caused by the transient responses of the various types of signal conditioning filters, which are generally introduced for the automated EEG analysis. This study explicitly simulates the filter responses to the typical EEG waveform models, and compares the distortions.

• Journal of Biomedical Engineering Research
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• v.11 no.2
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• pp.249-256
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• 1990

In this study, LPC cepstrum coefficients are used as feature vector extracted from AR model of EMG signal, and a reduced-connection network whlch has reduced connection between nodes is constructed to classify and recognize EMG functional classes. The proposed network reduces learning time and improves system stability Therefore it is Ehown that the proposed network is appropriate in recognizing function of EMG signal.

• Journal of Biomedical Engineering Research
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• v.11 no.1
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• pp.65-70
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• 1990

The phenomenon of color sensory has been mainly studied on the relation with the stimulus source of light source color according to dispersed energy of light. However, it has not been definitely found that the phenomenon of color sensory be collcerned with evoked potentials stimulated by object color. This paper proposes the method that evoked potentials stimulated by object colors are analyzed and examined on the phenomemon of color sensory. The model of evoked potentials is assumed that it is consisted of an additive noise and a transient signal caused by stimulus. The method which is used to estimate the signal is time-varying filtering.

• Journal of Biomedical Engineering Research
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• v.12 no.4
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• pp.261-266
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• 1991

As the ensemble averaged dz/dt signal during exercise gets smoothed, it is difficult to find the distinctive marks for estimation of stroke volume. The cross correlation function was made use of estimating these marks for automatic calculation by computer from the ensemble averaged dz/dt signal. LVET( Left Ventricular Ejection Time) and stroke volume were estimated based on the calculated parameters from the characteristic points. LVET, stroke volume calculated by hand, by the ensemble average and the cross correlation were compared for accuracy validation.

• Journal of Biomedical Engineering Research
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• v.18 no.1
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• pp.79-86
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• 1997

This paper describes the development of portable arousal measurement and analysis system. Skin impedance change which responds to the change of arousal level was detected by the three elctrode constant current method and separated into two components(SIR, SIL). Relationship between Nz, IRI and arousal level was studied and criteria of arousal level control was decided by the sleep study. Measured data with and without warning signal were compared and analyzed.

• Proceedings of the KOSOMBE Conference
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• v.1993 no.11
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• pp.137-140
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• 1993

This paper describes a Chaos analyzer and its applications to characteristic analysis of ECG signals and the other signals. We can detect chaotic system among the various system by quantitative and qualitative analysis using the proposed system. And we also propose a new Possibility to recognize abnormal state of ECG signal using the chaotic characteristcs of signal.

• Asian Pacific Journal of Cancer Prevention
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• v.17 no.12
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• pp.5087-5094
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• 2016

mTOR, the mammalian target of rapamycin, is a conserved serine/threonine kinase which belongs to the phosphatidyl-linositol kinase-related kinase (PIKK) family. It has two complexes called mTORC1 and mTORC2. It is well established that mTOR plays important roles in cell growth, proliferation and differentiation. Over-activation of the mTOR pathway is considered to have a relationship with the development of many types of diseases, including polycystic ovary syndrome (PCOS) and ovarian cancer (OC). mTOR pathway inhibitors, such as rapamycin and its derivatives, can directly or indirectly treat or relieve the symptoms of patients suffering from PCOS or OC. Moreover, mTOR inhibitors in combination with other chemical-molecular agents may have extraordinary efficacy. This paper will discuss links between mTOR signaling and PCOS and OC, and explore the mechanisms of mTOR inhibitors in treating these two diseases, with conclusions regarding the most effective therapeutic approaches.

• Proceedings of the Korean Society of Potoscience Conference
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• spring
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• pp.51-57
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• 2003

• Proceedings of the Korean Biophysical Society Conference
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• 2001.06a
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• pp.23-23
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• 2001

To evaluate the contribution of cAMP/PKA signal pathway in short-term facilitation, we overexpressed Ap oal receptor in sensory neurons that do not normally express this receptor. We have previously shown that activation of this receptor in sensory cells, by a brief treatment with octopamine (OA), produced short-term facilitation such as membrane depolarization, increase in membrane excitability, spike broadening, and enhanced neurotransmitter release in non-depressed synapse.(omitted)

• Journal of Biomedical Engineering Research
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• v.22 no.3
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• pp.285-291
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• 2001

In this paper, we designed two preprocessing adaptive filter - high pass filter and notch filter - using FPGA. For minimizing the calculation load of multi-channel and high-resolution ECG system, we utilize FPGA rather than digital signal processing chip. To implement the designed filters in FPGA, we utilize FPGA design tool(Altera corporation, MAX-PLUS II) and CSE database as test data. In order to evaluate the performance in terms of processing time, we compared the designed filters with the digital filters implemented by ADSP21061(Analog Devices). As a result, the filters implemented by FPGA showed better performance than the filters based on ADSP21061. As a consequence of examination, we conclude that FPGA is a useful solution in multi-channel and high-resolution signal processing.