• Proceedings of the Korean Society of Toxicology Conference
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• 2003.10b
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• pp.89-90
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• 2003

Biological products are composed of vaccines, antitoxin, blood products, DNA recombinant protein drugs, monoclonal antibody, cell therapy and gene therapy. Biological products are divided into traditional (i.e. recombinant proteins and monoclonal antibodies) and novel biological products (gene and cell therapy) and will require a similar re-evaluation of the approaches taken during each development program.(omitted)

• Proceedings of the PSK Conference
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• 2003.04a
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• pp.149.2-149.2
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• 2003

We have carried out a collaborative study to evaluate a candidate preparation of antithrombin III concentrate whether it is suitable to serve as a Korea National Biological Standard. Three National Control Laboratories and three manufacturers participated in this study. The potency of this candidate preparation was determined by using a heparin cofactor chromogenic method described in the Minimum Requirements for Biological Products and the European Phamacopoeia. (omitted)

• Proceedings of the PSK Conference
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• 2002.10a
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• pp.272.1-272.1
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• 2002

We have carried out collaborative study to evaluate a preparation of antithrombin concentrate whether or not it was suitable to serve as the candidate for a Korea National Biological Standard. Six laboratories. including three manufacturers and three National Control Laboratories. participated in this study. The potency of this candidate preparation was determined using the heparin cofactor chromogenic method. (omitted)

• Journal of the Korean Society of Environmental Restoration Technology
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• v.18 no.6
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• pp.27-38
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• 2015

This study is for deriving an evaluation system which fits to the domestic urban river. For this, two times of Delphi survey was conducted to various experts who are eminent for ecology, urban design, governance, landscape architecture, hydrology. The purpose was for analysing validity and getting extra opinion of evaluation items which were preferentially have chosen. Reflecting $1^{st}$ survey's opinions as changing the word or explaining more details, the second survey was conducted, In this time, all evaluation items were analysed as valid and experts agreed with that. In conclusion, the evaluation items, "Amenity", "Biodiversity", "Ecosystem service", "Governance", "Management", which are for evaluating domestic urban river environment were derived.

• Proceedings of the Korean Society of Life Science Conference
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• 2008.10a
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• pp.43.1-43.1
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• 2008

• Korean Journal of Biological Psychiatry
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• v.2 no.2
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• pp.193-204
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• 1995

Traumatic brain injury(TBI) used to be developed after a severe traumatic event. Therefore TBI usually induces acute or chronic stress reaction. I reviewed the concept, epidemiology, biological or psychosocial etiology, diagnosis and treatment of post-traumatic stress disorder (PTSD), and discussed about PTSD or stress reaction after TBI. Early evaluation and management of stress reaction after TBI are important.

• Proceedings of the Zoological Society Korea Conference
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• 2001.10a
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• pp.142-142
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• 2001

No Abstract, See Full Text

• Bulletin of the Korean Chemical Society
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• v.24 no.7
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• pp.1017-1020
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• 2003

• Journal of Ginseng Research
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• v.41 no.3
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• pp.373-378
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• 2017

Ocotillol-type saponins are one kind of tetracyclic triterpenoids, sharing a tetrahydrofuran ring. Natural ocotillol-type saponins have been discovered in Panax quinquefolius L., Panax japonicus, Hana mina, and Vietnamese ginseng. In recent years, the semisynthesis of 20(S/R)-ocotillol-type saponins has been reported. The biological activities of ocotillol-type saponins include neuroprotective effect, antimyocardial ischemia, antiinflammatory, antibacterial, and antitumor activities. Owing to their chemical structure, pharmacological actions, and the stereoselective activity on antimyocardial ischemia, ocotillol-type saponins are subjected to extensive consideration. In this review, we sum up the discovery, semisynthesis, biological activities, and metabolism of ocotillol-type saponins.

• Journal of Microbiology and Biotechnology
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• v.31 no.7
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• pp.956-966
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• 2021

To prevent the outbreak of infectious diseases that inflict huge economic and social losses, domestic livestock farms and related facilities have introduced automatic and semiautomatic disinfectant solution-spraying systems for vehicles. However, the facility standards and specifications vary by manufacturer, and no scientific performance evaluation has been conducted. The puropose of this study is to develop physical and biological evaluation methods. Physical and biological appraisals were conducted using two types of disinfection facilities (tunnel- and U-type) and two types of vehicles (passenger car, truck). Water-sensitive paper was used to evaluate the physical performance values for the disinfection facilities. In addition, to assess their biological performance, carriers containing low-pathogenic avian influenza virus were attached to vehicles, and the viral reduction was measured after the vehicles moved through the facility. The tunnel-type had rates of coverage in the range of 70-90% for the passenger car and 60-90% for the truck. At least 4-log virus reduction after spraying for 1-5 min was shown for both vehicles. For the U-type facility evaluation, the coverage rates were in the range of 60-90% for the passenger car and at least 90% for the truck. More than 4-log viral reduction was estimated within a spraying time of 5 min. To reduce viruses on the surface of vehicles by at least 4 log within a short period, the disinfectant solution should cover at least 71% of the pathogens. In conclusion, we were able to assess the physical and biological performance criteria for disinfection facilities aboard transportation vehicles.