• Title/Summary/Keyword: Bio-nano

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A Study on the $SO_2/CO_2/N_2$ Mixed Gas Separation Using Polyetherimide/PEBAX/PEG Composite Hollow Fiber Membrane (Polyetherimide/PEBAX/PEG 복합 중공사막을 이용한 $SO_2/CO_2/N_2$ 혼합기체 분리에 관한 연구)

  • Hyung, Chan-Heui;Park, Chun-Dong;Kim, Kee-Hong;Rhim, Ji-Won;Hwang, Taek-Sung;Lee, Hyung-Keun
    • Membrane Journal
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    • v.22 no.6
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    • pp.404-414
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    • 2012
  • In order to investigate $SO_2$ removal, PEI hollow fiber membranes were produced by a dry-wet phase inversion method. The membrane support layer on surface was coated with PEBAX1657$^{(R)}$ and PEG blending materials. Modules were prepared for the single gas permeation characteristics of composite membrane according to temperature and pressure. As a result, $SO_2$ permeance and $SO_2/N_2$ selectivity were 220~1220 GPU and 100~506 through operating condition, respectively. Moreover, $SO_2/CO_2/N_2$ mixture gas was used to compare the performance of separation properties according to temperature, pressure and retentate flow rate difference. $SO_2$ removal efficiency was increased with pressure and temperature.

Emotion-on-a-chip(EOC) : Evolution of biochip technology to measure human emotion (감성 진단칩(Emotion-on-a-chip, EOC) : 인간 감성측정을 위한 바이오칩기술의 진화)

  • Jung, Hyo-Il;Kihl, Tae-Suk;Hwang, Yoo-Sun
    • Science of Emotion and Sensibility
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    • v.14 no.1
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    • pp.157-164
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    • 2011
  • Emotion science is one of the rapidly expanding engineering/scientific disciplines which has a major impact on human society. Such growing interests in emotion science and engineering owe the recent trend that various academic fields are being merged. In this paper we propose the potential importance of the biochip technology in which the human emotion can be precisely measured in real time using body fluids such as blood, saliva and sweat. We firstly and newly name such a biochip an Emotion-On-a-Chip (EOC). EOC consists of biological markers to measure the emotion, electrode to acquire the signal, transducer to transfer the signal and display to show the result. In particular, microfabrication techniques made it possible to construct nano/micron scale sensing parts/chips to accommodate the biological molecules to capture the emotional bio-markers and gave us a new opportunities to investigate the emotion precisely. Future developments in the EOC techniques will be able to help combine the social sciences and natural sciences, and consequently expand the scope of studies.

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Preparation of Flexible 3D Porous Polyaniline Film for High-Performance Electrochemical pH Sensor (고성능 전기 화학 pH 센서를 위한 유연한 3차원 다공성 폴리아닐린 필름 제조)

  • Park, Hong Jun;Park, Seung Hwa;Kim, Ho Jun;Lee, Kyoung G.;Choi, Bong Gill
    • Applied Chemistry for Engineering
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    • v.31 no.5
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    • pp.539-544
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    • 2020
  • A three-dimensional (3D) porous polyaniline (PANI) film was fabricated by a combined photo-and soft-lithography technique based on a large-area nanopillar array, followed by a controlled chemical dilute polymerization. The as-obtained 3D PANI film consisted of hierarchically interconnected PANI nanofibers, resulting in a 3D hierarchical nanoweb film with a large surface and open porous structure. Using electrochemical measurements, the resulting 3D PANI film was demonstrated as a flexible pH sensor electrode, exhibiting a high sensitivity of 60.3 mV/pH, which is close to the ideal Nernstian behavior. In addition, the 3D PANI electrode showed a fast response time of 10 s, good repeatability, and good selectivity. When the 3D PANI electrode was measured under a mechanically bent state, the electrode exhibited a high sensitivity of 60.4 mV/pH, demonstrating flexible pH sensor performance.

Application of Isolated Tyrosinase Inhibitory Compounds from Persimmon Leaves (감나무 잎으로 부터 분리한 tyrosinase 억제물질의 응용)

  • Cho, Young-Je;An, Bong-Jeun;Kim, Jeung-Hoan
    • Journal of Life Science
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    • v.21 no.7
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    • pp.976-984
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    • 2011
  • Total phenolic content was the highest in 60% ethanol extracts at 21.91 mg/g, and inhibitory activity against tyrosinase of 60% ethanol extracts was higher than ethanol extracts of other concentration. The inhibitory compounds against tyrosinase from Persimmon leaves were purified using Sephadex LH-20, MCI-gel CHP-20 column chromatography with gradient elution. Two purified compounds were isolated as a result. The chemical structures of each compound were determined and identified using $^1H$-NMR and $^{13}C$-NMR, FAB-Mass. The compounds were confirmed as (+)-gallocatechin and prodelphinidin B-3. The tyrosinase inhibitory activities of purified (+)-gallocatechin and prodelphinidin B-3 were 29.5 and 40.2%, respectively. The inhibitory activities of (+)-gallocatechin and prodelphinidin B-3 against melanin biosynthesis in melanoma cell were 32.5 and 46.7%. The safety of essence with tyrosinase inhibitory compounds from persimmon leaves was also assessed by various safety profiles. First, changes in pH (4.90~4.95) and viscosity (23,000~26,000 cP) was not detected for 60 days. Essence also showed stability against temperature and light for 60 days. All these findings suggest that extracts from persimmon leaves have a great potential as a cosmetical ingredient with a potent whitening effect.

Ultrasmall Polyethyleneimine-Gold Nanoparticles with High Stability (높은 안정성을 갖는 초미립 폴리에틸렌이민-금 나노입자)

  • Kim, Eun-Jung;Yeum, Jeong-Hyun;Ghim, Han-Do;Lee, Se-Guen;Lee, Ga-Hyun;Lee, Hyun-Ju;Han, Sang-Ik;Choi, Jin-Hyun
    • Polymer(Korea)
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    • v.35 no.2
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    • pp.161-165
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    • 2011
  • This study is related to the preparation of biocompatible gold nanoparticles (AuNPs) which are stable in aqueous solutions for a long time. Ultrasmall polyethyleneimine (PEI)-capped AuNPs (PEI-AuNPs) with limited agglomeration were prepared in aqueous solutions at room temperature, which were based on the roles of PEI as a reductant and a stabilizer. PEI-AuNPs with an average size of 8~12 nm formed highly stable nanocolloids with an average hydrodynamic cluster size of around 50 nm in aqueous media. At a low concentration of metal precursor hydrogen tetrachloroaurate (III), the particle size was reduced noticeably. The typical peaks of gold were observed in the X-ray diffraction pattern of AuNPs. The cell viability of 98% was obtained in the case of PEI-AuNPs, while PEI was cytotoxic. The PEI-AuNP is considered to be a potential candidate as a contrast agent for computed tomography.

Study on Isothermal Crystallization Characteristics of PLA Film by Adding APP as a Nucleation Agent (APP 핵제를 첨가한 PLA 필름의 등온결정화 특성에 관한 연구)

  • Kim, Gyu-Sun;Kim, Moon-Sun;Kim, Byung-Woo
    • Korean Chemical Engineering Research
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    • v.50 no.3
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    • pp.582-587
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    • 2012
  • In this paper, it was studied on the crystallization characteristics of PLA film by adding ammonium phosphate (APP) as a nucleation agent. Crystallinity and crystallite size of PLA film were determined by Scherrer equation. Crystallization rate constant of PLA film was calculated through Avrami equation. Film samples in the study were prepared by two steps. PLA films were prepared by adding 1, 5, and 10 wt%, respectively, at first and was secondly annealed at 130, 140, and $150^{\circ}C$. Crystallinity of pure PLA film was average 4.6% and those of PLA film with adding 1, 5, and 10 wt% APP were 12.2, 47.7, and 50.0%, respectively. Crystallite size of PLA film was average 28.0 nm and those of PLA film with adding 1, 5, and 10 wt% APP were 26.8, 24.0, and 19.0 nm, respectively. Crystallization rate constants of PLA film with 1 wt% APP were 2.12, 3.86, and 0.27 by annealing at 130, 140, and $150^{\circ}C$, respectively, where was higher than pure PLA film and those with adding 5 and 10 wt% APP, respectively.

A Study on the Usefulness of 3D Imaging in Micro-CT for Observing the Microstructure of Mice (흰쥐 미세구조 관찰을 위한 Micro-CT 3D 영상의 유용성에 관한 연구)

  • Lee, Sang-Ho;Lee, Jong-Seok;Lim, Cheong-Hwan;Jung, Hong-Ryang;Chai, Kyu-Yun;Han, Beom-Hee;Han, Sang-Hyun;Hong, Dong-Hee;Han, Tae-Jong;Park, Sung-Hoon;Mo, Eun-Hee;Jun, Hong-Young
    • Journal of Digital Convergence
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    • v.12 no.3
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    • pp.367-375
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    • 2014
  • In this thesis we observe microvascular structure in mice by using micro-computed tomography (CT), which is high-resolution X-ray imaging equipment that can acquire Real-time dynamic image, and it aims to investigate the usefulness of micro-CT developed by Institute for Radiological Imaging Science Wonkwang University School of Medicine. After acquiring the systemic images of rats, contrast-enhanced 3D images of vascular structures could be acquired by using Maximum Intensity Projection (MIP) and Volume Rending Technique (VRT), This was divided into each vascular system of head, abdomen and heart and systemic vascular system.

Anti-oxidative Activity and Chemical Composition of Various Heracleum moellendorffii Hance Extracts (추출 조건에 따른 어수리의 항산화 활성 및 성분 분석)

  • Bang, Ji-Eun;Choi, Hae-Yeon;Kim, Sun-Im
    • Food Science and Preservation
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    • v.16 no.5
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    • pp.765-771
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    • 2009
  • Anti-oxidative activities of Heracleum moellendorffii Hance extracts were measured after extraction with 50% (v/v) ethanol or water (at $80^{\circ}C$ or $20^{\circ}C$). The total polyphenol content was highest (64.73 mg GAE/g) in extract from 50% ethanol extraction at $80^{\circ}C$. In extracts obtained by water extraction at $80^{\circ}C$ and $20^{\circ}C$, the total polyphenol contents were 39.78 mg GAE/g and 23.17 mg GAE/g, respectively. The antioxidant activities of the ethanol extract at $80^{\circ}C$ were highest, as assessed by DPPH radical scavenging activity (69.14% at 50 ppm), reducing power (OD 0.93), and $ABTS^+$ radical-scavenging activity (85.62% at 1,000 ppm). At $80^{\circ}C$, the antioxidant activity of the 50% (v/v) ethanol extract was 8-20% higher than that of the water extract. Also, the chemical composition of extract from ethanol extraction at $80^{\circ}C$ was analyzed. The levels of moisture, crude protein, crude fat, and crude ash were 6.38%, 4.35%, 0.67%, and 1.96%, (all w/w), respectively. The Na, K, Mg, Zn, Fe, Ca, and P contents of the extract were 53.41, 398.26, 5.80, 0.40, 5.27, 3.56, and 47.17 mg/100 g, respectively. The total levels of polyphenolic compounds and flavonoids in the ethanol extract were 64.73 mg GAE/g and 49.54 mg RE/g.

Analysis on the Curriculum of Chemical Engineering Field in Specialized Vocational High School (특성화고 화공계열의 교육과정에 대한 실태 분석)

  • Lee, Kyu-Nyo;Yi, Kwang bok;Kim, So Yeon;Han, Soo Kyong;Rhee, Young-Woo
    • 대한공업교육학회지
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    • v.40 no.2
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    • pp.72-91
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    • 2015
  • This study is aimed at researching and analyzing the actual conditions of the curriculum and career path of chemical engineering field in specialized high school, and seeking for a curriculum improvement plan for activation by means of identity establishment of chemical engineering field. This study surveyed the actual conditions of school (department) regarding chemical engineering, and analyzed an adequacy among the curriculum, department name and acquired license. The results are as follows. Firstly, In order to the chemical engineering field to maintain the identity of chemical engineering and accept the changes in the industrial site, it is desirable for the department name to use the name of applied science, such as Applied Chemical Industry, Nano Chemical Industry, Environmental Chemical Industry, Energy Chemical Industry, Convergence Materials Science and Chemical Engineering, Ceramic Chemical Engineering, Biomolecular and Chemical Engineering, and Food Bio-chemical Engineering, which are derived from chemical engineering, and the revision of curriculum should be included. Secondly, it is necessary to diversify relevant licenses by standard department of chemical engineering field, and clarify the purpose of human resources development and the image of talented, considering the future course of graduates and the demand of industry, for the purpose of improving school-leveled curriculum to raise the possibility of employment. Thirdly, in accordance with the changing paradigm that secondary vocational education is changed from 'just-to-know education (knowledge)' to 'can-do education (capability)', it is necessary to make the performance ability-centered curriculum in which 'chemical engineering industry - chemical engineering vocational education - chemical engineering qualification' are integrated.

Real-Time Variable Speed Limits for Urban Freeway (도시고속도로를 위한 실시간 가변 속도 제한)

  • Jo, Young-Tae;Jung, In-Bum
    • Journal of KIISE:Computing Practices and Letters
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    • v.16 no.10
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    • pp.962-974
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    • 2010
  • Recently, the convergence of information technology with bio-technology, nano-technology or other technologies has been creating a new paradigm. In a field of transportation, the intelligent transport systems which is a convergence of intelligent technologies and transportation systems have been studied. The Variable Speed Limit(VSL), is one of ITS technologies, is thought to improve safety and efficiency of transportation while controlling speed limit based on road conditions. Legacy studies have considered only one station for VSL algorithm. However, it is not appropriate for an urban freeway installed with many stations. In this paper, new algorithm is proposed to not only enhance effectiveness of VSL based on cooperation of stations but also reflect road conditions within 30 seconds. The proposed algorithm consists of 4 steps: the first is a "searching bottleneck station" step, the second is a "calculating a size of congestion" step, the third is a "calculating the number of controlled stations" step, the final is a "calculating VSL" step. This algorithm guarantees improved safety and minimum additional travel time. The travel time should be considered because drivers would against the VSL algorithm when the proposed algorithm occurs additional travel time. In our experiments, microscopic traffic simulator VISSIM is selected to perform a modeling work. The results show that proposed algorithm provides the improved safety and minimum increase of travel time.