• 대한상부위장관⦁헬리코박터학회지
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• 제18권3호
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• pp.150-156
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• 2018

Precision medicine stands for 4Ps - precise, preventive, participatory, and personal; in which "precision" is important because the current modern medicine starts from "trial and error," and "one does not fit all". Current targeted therapies for cancer have changed treatment approaches and led the precision medicine; however, clinical use of liquid biopsy, using blood or other liquid specimens to characterize circulating tumor cells (CTC) or tumor genes instead of biopsies of tumor tissues, still awaits availability of more information regarding non-invasive cancer detection and characterization, prediction of treatment response, monitoring the disease course and relapse possibilities, identification of mechanisms of drug resistance, and newer pathogenesis. In this review, we will introduce the basic concept of CTC, circulating cell free DNA, and exosomes and their possible application for gastric cancer relevant with Helicobacter pylori infection.

• 농업과학연구
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• 제46권1호
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• pp.57-65
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• 2019

The purpose of this study was to develop an environment field monitoring system to measure crop growth. The environment field monitoring system consisted of sensors, a data acquisition system, and GPS. The sensors used in the environment field monitoring system consisted of an ambient sensor, a soil sensor, and an intensity sensor. The temperature and humidity of the atmosphere were measured with the ambient sensor. The temperature, humidity, and EC of the soil were measured with the soil sensor. The data acquisition system was developed using the Arduino controller. The field monitoring data were collected before a rainy day, on a rainy day, and after the rainy day. The measured data using the environment field monitoring system were compared with the Daejeon regional meteorological office data. The correlation between the data from the environment field monitoring system and the data from the Daejeon regional meteorological office was analyzed for performance evaluation. The correlation of the temperature and humidity of the atmosphere was analyzed because the Daejeon regional meteorological office only provided data for the temperature and humidity of the atmosphere. The correlation coefficients were 0.86 and 0.90, respectively. The result showed a good correlation between the data from the environment field monitoring system and the data from the Daejeon regional meteorological office. Therefore, the developed system could be applied to monitoring the field environment of agricultural crops.

• 전자공학회논문지 IE
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• 제49권2호
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• pp.82-88
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• 2012

본 논문에서는 안드로이드 기반의 모바일 플랫폼을 이용한 통합형 유헬스케어 시스템 설계하여 개인의 건강관리 서비스를 위한 시스템을 제안하였다. 통합형 생체 계측 시스템은 심전도, 산소포화도, 혈압, 호흡, 체온 등 모듈을 통하여 생체 신호를 계측하고 신호처리된 생체 정보를 무선 통신모듈을 이용하여 안드로이드 기반의 모바일 플랫폼 게이트웨이로 전송한다. 전송된 생체 데이터는 모바일 시스템에서 건강상태를 감시하거나 유헬스케어 서버로 전송하도로 설계하였다. 생체신호 감시 시스템을 구현함으로서 측정되어진 생체 데이터를 모니터링하여 현재의 건강상태를 확인할 수 있었으며 보호자의 이동성을 보장할 수 있는 장점을 보였다. 이와 같은 시스템은 개인 건강관리 및 응급환자 감시 시스템을 위한 유헬스케어 시스템 발전에 도움이 되리라 본다.

• 대한기계학회논문집A
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• 제32권10호
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• pp.844-849
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• 2008

We present a novel cell deformability monitoring chip based on the digitally measured cell lysis rate which is dependent on the areal strain of the cell membrane. This method offers simple cell deformability monitoring by automated high-throughput testing system. We suggest the filter design considering the areal strain imposed on the cell membrane passing through the filter array having gradually increased orifice length. In the experiment using erythrocytes, we characterized the cell deformability in terms of average fracture areal strain which was $0.24{\pm}0.014\;and\;0.21{\pm}0.002$ for normal and chemically treated erythrocytes, respectively. We also verified that the areal strain of 0.15 effectively discriminates the deformability difference of normal and chemically treated erythrocytes, which can be applied to the clinical situation. We compared the lysis rates and their difference for the samples from different donors and found that the present chips can be commonly used without any calibration process. The experimental results demonstrate the simple structure and high performance of the present cell deformability monitoring chips, applicable to simple and cost-effective cell aging process monitoring.

• KSBB Journal
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• 제26권5호
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• pp.412-416
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• 2011

The conventional monitoring system for water pollution measurement is quite simple and independent and it has a lot of draw backs such as cost, installation, etc. So, in this paper, we have measured the water pollution system through a bacterial species, photobacterium phosphoreum. A novel integrated monitoring system technology has been developed which could easily dictate and analyze the major water pollutants and its surrounding environment in an accurate way. The system constitutes of bionic technology, information technology and environmental engineering technology. As a result, integrated monitoring system can observe the water pollution and various water environment of the whole country. Also, through the sensors of USN, Zigbee, RFID and middle ware, which can provide service and construct service platform, a properly standardized plan with remarkable service platform has been established through this investigation.

• 한국환경보건학회지
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• 제32권1호
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• pp.46-52
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• 2006

Results for the concentrations of total polychlorinated biphenyls (total PCBs) and the PCB profile with different types of leaves from four coniferous trees (pine needles) at the same sampling site are presented. Concentrations of total PCBs detected in pine needles were very similar among them regardless of their different types of leaves, which means a possibility for bio-monitoring regional contamination of PCBs. Correlation coefficients(r) of PCB congeners between pine needles were very significant (r>0.97, p<0.001), which showed that PCB congener's patterns of each pine needle were similar. Profiles of PCBs detected in pine needles showed correlation with gaseous phase PCBs in air, otherwise not with particle phase PCBs in air. Therefore, it was estimated that dry gaseous deposition was a principal pathway of PCBs accumulation in pine needles. In addition, although we analyse a different types of leaves in pine needles at the same region, they can be used to identify regional contamination patterns of PCBs for larger regions.

• Biotechnology and Bioprocess Engineering:BBE
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• 제11권5호
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• pp.432-441
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• 2006

2D fluorescence sensors produce a great deal of spectral data during fermentation processes, which can be analyzed using a variety of statistical techniques. Principal component analysis (PCA) and a self-organizing map (SOM) were used to analyze these 2D fluorescence spectra and to extract useful information from them. PCA resulted in scores and loadings that were visualized in the score-loading plots and used to monitor various fermentation processes with recombinant Escherichia coli and Saccharomyces cerevisiae. The SOM was found to be a useful and interpretative method of classifying the entire gamut of 2D fluorescence spectra and of selecting some significant combinations of excitation and emission wavelengths. The results, including the normalized weights and variances, indicated that the SOM network is capable of being used to interpret the fermentation processes monitored by a 2D fluorescence sensor.

• 한국정보통신학회:학술대회논문집
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• 한국해양정보통신학회 2009년도 추계학술대회
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• pp.585-588
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• 2009

무선센서네트워크는 처리능력과 자원이 제한된 수많은 소형의 센서노드들로 구성된다. 따라서 무선센서네트워크에 있어서 가장 중요하고 기본적인 요소는 환경 정보를 수집하고 이를 사용자 응용시스템에 전송하는 센서노드 기술이다. 기술의 발전에 따라 센서노드는 점점 소형화 되고 지능화 되어 그 응용범위를 넓혀가고 있다. 특히 이식형 센서노드 기술은 인체나 가축의 체내에 이식되어 질병을 감시하고 치료하는데 사용됨으로써 무선센서네트워크의 미래 발전 방향을 제시한다. 본고에서는 가축의 체온을 실시간으로 감시할 수 있는 이식형 무선 센서노드를 설계하였다. 또한, 실시간 생체 감시 시스템 구현을 위한 추가적인 고려사항에 대하여 논하였다.

• Journal of Species Research
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• 제12권2호
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• pp.189-196
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• 2023

We monitored the hitchhiker insect pests from the international vessels entering into Korea in 2021. As a result, total of 581 individuals were detected by the survey based on visual inspection with naked eye. Among them, 500 individuals were identified as 244 species of 65 families under 11 orders through the integrative taxonomic method with DNA barcoding and morphological reexamination, but the remaining 81 individuals were classified as only to the family level. Of the 244 species identified, 26 species were determined to be not-distributed species in Korea (two Orthoptera, two Hemiptera, one Megaloptera, five Coleoptera, three Hymenoptera, and 13 Lepidoptera). Among them, two species, Sagra femorata (Chrysomelidae, Coleoptera) and Dendrolimus punctatus (Lasiocampidae, Lepidoptera), were discovered as 'Regulated species' listed by Animal and Plant Quarantine Agency, South Korea. Therefore, we reported on the 26 not-distributed species in Korea and provided inanimate pathway information such as navigation routes on the vessels hitchhiking the species, state of the samples at the time of detection, identification results and original distribution for the detailed monitoring and the risk analysis on the species.

• 한국컴퓨터정보학회:학술대회논문집
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• 한국컴퓨터정보학회 2016년도 제54차 하계학술대회논문집 24권2호
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• pp.283-284
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• 2016

본 논문에서는 다중 생체계측 장비를 CMCIS(Central Monitoring and Cardiology Information System) 기반의 통합 시스템에 연동하기 위한 내장형 MDEC 모듈을 소개하고 바이탈 사인 장비와 결합하여 무선 네트워킹을 통하여 원격지에 생체정보를 전송하는 시스템을 제안한다. 내장형 MDEC 모듈로 전송된 데이터는 실시간 뷰에 표시됨으로서 환자정보를 원격지에서 감시 및 관리할 수 있는 유효성을 가지게 된다. 본 연구의 결과는 CMCIS 기반의 통합 시스템을 구축하는 기반기술로 향후 효율적 의료서비스에 기여할 것으로 사료된다.