• Asian-Australasian Journal of Animal Sciences
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• v.20 no.7
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• pp.1084-1091
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• 2007

Different levels of dietary mannanoligosaccharide (Bio-MOS, Alltech Inc.) were evaluated for their efficacy on performance and gut development of broiler chickens during a 6-week experimental period. Experimental diets contained (g MOS/kg diet) a low (0.5 g during the entire period), medium (1 g during the entire period), high (2 g during the entire period), or step down (2 g in the first week; 1 g in the second and third week; 0.5 g in the last three weeks) level of MOS. Control diets included a negative and a positive control (zinc bacitracin, ZnB, 50 ppm and 30 ppm in the first and last three weeks, respectively). MOS supplementation improved the growth performance of young birds and the effects became less when the birds got older. The growth response of birds was more obvious at the high dosage level of MOS treatment than the other MOS treatments and the growth performance of birds fed on the high MOS diet was comparable to that of birds fed on the ZnB diet. Depending on the dosage level and the age of birds, MOS seemed to reduce the size of the liver and the relative length of the small intestine but did not affect the relative weight of the other visceral organs (proventriculus, gizzard, pancreas, bursa and spleen) and that of the small intestine. A numerical increase in the small intestine digestibility of nutrients was noticed in the young birds fed on the MOS diet(s), but not in the older ones. Medium and/or high MOS treatment also increased the villus height of the small intestine of birds at different ages. Similar results were observed on the ZnB treatment. However, MOS and ZnB affected caecal VFA profile in different ways. MOS increased, or tended to increase, whereas ZnB reduced individual VFA concentrations in the caeca.

• Asian-Australasian Journal of Animal Sciences
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• v.14 no.4
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• pp.559-563
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• 2001

The effects of feeding a mannan oligosaccharide (Bio-Mos) from 0 to 3 g/kg diet and vaccination program on 1- to 35-day performance (growth and feed efficiency), metabolizable energy, nitrogen utilization and carcass composition of meat chickens were investigated. A general vaccination program was used against IB, IBD and ND with half of the birds per diet receiving a booster dose of IB and ND vaccines at 12 days of age. Dietary supplementation of Bio-Mos (BM) did not influence body weight gain, feed efficiency and nutrient utilization. The highest dietary BM (3 versus 1.5 or 0 g/kg) increased carcass abdominal fat and reduced the proportion of drumstick in the carcass of meat chickens. The booster dose reduced the performance of birds. It was concluded that the addition of BM to the diet of chickens did not significantly influence the performance and nutrient utilization of meat chickens.

• Proceedings of the Korean Society for Bio-Environment Control Conference
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• 2002.11a
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• pp.203-211
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• 2002

원예용상토의 국내 소개는 1980년대 후반에 해외 제품 중 유럽산 Black Peat Moss가 주재료로 사용된 상토(Soilless Media, Potting Soil)를 농가에 처음으로 보급하기 시작하였고, 90년대 초반에는 코코넛 열매의 부산물인 Coco Peat(Coir Dust)을 유기물 주재료하고 무기물재료로 Zeolite를 혼합한 국내산 상토가 처음으로 제조 공급되었고, 그 이후로는 유기물은 Peat Moss와 Coco Peat를 혼합 또는 단용으로 하고 무기물 재료는 Zeolite, Perlite, Vermiculite 등을 첨가한 다양한 제품이 소비자에게 공급되기에 이르렀다. (중략)

• Bulletin of the Korean Chemical Society
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• v.30 no.11
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• pp.2535-2541
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• 2009

Prebiotic isomaltooligosaccharide preparations contain $\alpha$-D-glucooligosaccharides comprising isomaltooligosaccharides (IMOs) and non-prebiotic maltooligosaccharides (MOs). They are both glucose oligosaccharides characterized by their degree of polymerization (DP) value (from 2 to $\sim$10), linkages types and positions (IMOs: $\alpha$-(1$\rightarrow$2, 3, 6 and in a lower proportion internal 1$\rightarrow$4) linkages, MOs: α-(1$\rightarrow$4) linkages). Their structure is the key factor for their prebiotic potential. In order to determine and elucidate the exact structure of unknown IMOs and MOs, unambiguous assignments of $^{13}C$ and $^1H$ chemical shifts of commercial standards, representative of IMOs and MOs diversity, have been determined using optimized standard one and two-dimensional experiments such as $^1H$ NMR, $^{13}C$ NMR, APT and ${^1}H-{^1}H$ COSY, TOCSY, NOESY and <$^1H-{^{13}}C$ heteronuclear HSQC, HSQC-TOCSY, and HMBC. Here we point out the differential effect of substitution by a glucose residue at different positions on chemical shifts of anomeric as well as ring carbons together with the effect of the reducing end configuration for low DP oligosaccharides and diasteroisotopic effect for H-6 protons. From this study, structural $^{13}C$ specific spectral features can be identified as tools for structural analysis of isomaltooligosaccharides.

• Asian-Australasian Journal of Animal Sciences
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• v.16 no.10
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• pp.1495-1500
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• 2003

Two bio-assays were conducted to evaluate turmeric root powder and mannan-oligosaccharides (MOS) as alternatives to feed antibiotics for broilers. In one trial, one hundred and eighty 19-days old broilers assigned to 18 groups of 10 were fed on one of six experimental diets with three replicates during four weeks. The diets included a basal feed without additives and with either virginiamycin, MOS, or turmeric at 1, 2 and 3 g/kg, respectively. In the second trial, one hundred and forty four 21-days old broilers arranged in 16 groups of nine were fed on the first four diets with four replicates for a similar period. Virginiamycin, MOS and turmeric (1 g/kg) in the first trial generally improved the weight gain of broilers by 3.4, 6.2 and 5.3%, respectively. In the second trial they increased the weight gain significantly (p<0.05) by 8.8, 8.0 and 15.1%, respectively. Additives improved the feed efficiency up to 15.1% and carcass recovery up to 3.1% (p<0.05). Virginiamycin, MOS and turmeric (1 g/kg) markedly reduced the abdominal fat content from 1.91% BW in the control to 1.44, 0.97 and 1.2% BW, respectively, in the first trial. The corresponding values obtained in the second trial were 1.01, 0.55 and 0.6%, respectively as compared to 1.22% in the control group. All additives showed a remarkable inhibition of duodenal coliform bacteria, yeast and mould in the caecum, and all viable microbes in the ileum. A significant (p<0.05) improvement in energy and protein utilization could be recorded with supplemented diets except for high turmeric diets. Dietary 2 and 3 g/kg addition of turmeric reduced energy and protein utilization as well as fat deposition. Present results reveal that turmeric and MOS are satisfactory alternatives to antibiotics in broiler feeds. Both MOS and turmeric possess an antimicrobial effect in vivo. Turmeric may also depress fat deposition in broilers.

• Journal of Animal Science and Technology
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• v.48 no.5
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• pp.709-718
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• 2006

In order to know the effects of Garlic, Scallion, Flavonoid, Urushiol, Anthocyanidin and Bio-MOS?? on pathogenic microbes and rumen anaerobic microbes, the growth rate of pathogens (including Escherichia coli O157, Salmonella paratyphi, Listeria monocytogenes and Staphylococcus aureus) and in vitro rumen microbial growth, gas production, ammonia concentration, carboxymethylcellulase(CMCase) activity, and microbial populations were investigated.The growth of pathogens was inhibited by supplementation of 0.1% Flavonoid, Scallion or Bio-MOS?? as biological active materials. And Scallion and Flavonoid had powerful antimicrobial properties on the pathogens applied in paper disc method.Although few effects by biological active materials disappeared in rumen fermentation in vitro, CMCase activity removed with supplementation of 1% of Flavonoid which had antimicrobial property in paper disc method. Scallion, having powerful antimicrobial property on pathogens and no inhibiting on rumen fermentation, might be a source in development of natural antimicrobial agent for ruminants.

• Journal of the Korean Institute of Electrical and Electronic Material Engineers
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• v.25 no.9
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• pp.686-691
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• 2012

In this paper, we designed a Chua's chaotic circuit using transcondcutor based nonlinear resistor. Proposed chaotic circuit consist of L, C, R and transcondcutor based Chua's diode. We performed SPICE simulation for chaotic dynamics such as time seriesform, frequency analysis and phase plane of the circuit. Chaotic dynamics of the circuit was analysed according to MOS size variation of the operational transconductance amplifier. Also, we performed SPICE circuit analysis for temperature dependance of the circuit. SPICE results showed that chaotic dynamics of the circuit varied according to the temperature variation and chaotic signals were generated in specific temperature conditions.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.13 no.9
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• pp.4159-4164
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• 2012

This paper presents a chaotic circuit with voltage controllability for secure communication applications. The proposed circuit which has two control voltages consists of the nonlinear function block(NFB) with three MOS transistors, one source follower and non-overlapping two-phase clock generator for sample and hold. By SPICE simulation, chaotic dynamics such as time waveform, frequency analysis and bifurcations were analyzed. SPICE results showed that proposed circuit can make various chaotic signals by control voltage.

• Journal of Practical Agriculture & Fisheries Research
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• v.25 no.4
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• pp.53-59
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• 2024

The purpose of the study was to examine the effects of initial body weight and synbiotics supplementation in the diet on growth performance of weaned pigs. A total of 80 crossbred pigs (Landrace×Yorkshire×Duroc, d 28±3, body weight 6.40±1.70 kg) were randomly distributed 4 treatments (4 replication, 5 pigs/replication). The treatments were 1) high initial body weight group (PC), 2) low initional body weight group (NC), 3) low initial body weight with 0.2% antibiotics (amoxicillin) supplementaion group (AB), 4) low initial body weight with 0.2% synbiotics (AllTech^® Bio-Mos 0.3%, 0.3%, Bacillus subtillis 0.1%, formic acid 0.1%) supplementation group (Syn). AllTech^® Bio-Mos is consist of at least 25% of glucomannanprotein extracted from the cell wall of Saccaromycess cerevisae. Growth performance was measured during 28 d. Average daily gain (ADG) of AB and Syn groups were significantly (p<0.05) higher than that of NC group. However, final body weight at the end of experiment were not different among NC, AB, and Syn groups. Initial body weight and final body weight of PC group were statistically (p<0.001) higher compared to those of other groups. Additionally, PC showed the tendency of lower average daily feed intake and higher ADG, thereby lower feed conversion ratio compared with other groups. Therefore, the current results imply that supplementation of antibiotics and synbiotics in diets for weaned pigs could not catch up with significant differences in initial body weight.

• Toxicological Research
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• v.35 no.2
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• pp.131-136
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• 2019

Ethylhexyl dimethyl para-aminobenzoic acid (PABA) is an oily yellow liquid derivative of water-soluble PABA commonly used in sunscreen. Ethylhexyl dimethyl PABA is widely used as an ingredient in many cosmetics at an average concentration of 1.25% (0.5-2.0%) in Korea. Previous studies, including those involving animals, have demonstrated that ethylhexyl dimethyl PABA is toxic to the following four organs: testis, epididymis, spleen, and liver. In addition, experiments using human keratinocytes found that ethylhexyl dimethyl PABA inhibits cell growth and DNA synthesis at low concentrations, and halted the cell cycle of MM96L cells (human melanoma cell line) at the G1 phase. Despite limited clinical data in humans, many studies have confirmed increased mutagenicity of ethylhexyl dimethyl PABA following exposure to sunlight, which suggests that this molecule is likely to contribute to onset of sun-induced cancer despite protecting the skin through absorption of UVB. For risk assessment, the no observed adverse effect level (NOAEL) chosen was 100 mg/kg bw/day in a 4 weeks oral toxicity study. Systemic exposure dosage (SED) was 0.588 mg/kg bw/day for maximum use of ethylhexyl dimethyl PABA in cosmetics. Based on the risk assessment and exposure scenarios conducted in this study, the margin of safety (MOS) was calculated to be 180.18 for a sunscreen containing 8% ethylhexyl dimethyl PABA, which is the maximum level allowed by the relevant domestic authorities.