• 대한화학회지
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• 제34권5호
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• pp.424-429
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• 1990

Citrobacter freundii와 그의 organelle을 CO$_2$ gas-sensor에 고정시켜서 glucose 정량을 위한 biosensor를 조립하였다. 박테리아의 경우가 organelle 보다 감응은 우수하였으나 감응시간은 organelle의 경우가 훨씬 짧았다. 박테리아 전극은 30$^{\circ}C$의 온도에서 pH 7.0 인 0.2M tris-HCl 완충용액을 사용하면 7.0 ${\times}\;10^{-4}$ - 1.0 ${\times}\;10^{-2}$ M glucose 농도범위에서 42.2 mV/decade의 감응기울기를 나타냈다. 이 전극은 glucose에 대해서 선택성이 매우 우수하였으며, 혈청속의 glucose 정량에 사용한 결과 routine analyzer와 좋은 일치를 보였다.

• 대한의용생체공학회:의공학회지
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• 제26권5호
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• pp.271-282
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• 2005

There are strong demands for accurate, fast, and inexpensive devices in the medical diagnostic laboratories, such as biosensors and chemical sensors. Biosensors can provide the reliable and accurate informations on the desired biochemical parameters, which is an essential prerequisite for a patient before going for a treatment. They can be used for continuous measurements of metabolites, blood cations, gases, etc. Of these, electrochemical biosensors play an important role in the improvement of public health, because rapid detection, high sensitivity, small size, and specificity are achievable for clinical diagnostics. In this paper, the clinical applications with electrochemical biosensors are reviewed. An attempt is also made to highlight some of the trends that govern the research and developments of the important biosensors that are associated to clinical diagnosis.

• 한국소성가공학회:학술대회논문집
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• 한국소성가공학회 2005년도 춘계학술대회 논문집
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• pp.237-240
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• 2005

The demand of micro electrical mechanical system (MEMS) bio/chemical sensor is rapidly increasing. To prevent the contamination of sensing area, a filtration system is required in on-chip total analyzing MEMS bio/chemical sensor. A nano-filter was mainly applied in some application detecting submicron feature size bio/chemical products such as bacteria, fungi and so on. We suggested a simple nano-filter fabrication process based on replication process. The mother pattern was fabricated by holographic lithography and reactive ion etching process, and the replication process was carried out using polymer mold and UV-imprinting process. Finally the nano-filter is obtained after removing the replicated part of metal deposited replica. In this study, as a practical example of the suggested process, a nano-dot array was replicated to fabricate nano-filter fur bacteria sensor application.

• 반도체디스플레이기술학회지
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• 제17권4호
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• pp.76-79
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• 2018

In this paper, we developed a pressure monitoring system using silicon pressure sensor. The pressure monitoring system was developed on the basis of a microcontroller, and a self-developed silicon pressure sensor was applied. The pressure monitoring system outputs the current pressure value via UART communication. In addition, it includes a function of displaying by LED when the preset three-step pressure (low, medium, high pressure) is reached. The silicon pressure sensor used in the pressure monitoring system was set to 0 kPa, 10 kPa, 26 kPa, and the pressure monitoring system was evaluated because the measured maximum pressure was in the range of 100 kPa.

• 한국정보통신학회:학술대회논문집
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• 한국해양정보통신학회 2009년도 추계학술대회
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• pp.585-588
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• 2009

무선센서네트워크는 처리능력과 자원이 제한된 수많은 소형의 센서노드들로 구성된다. 따라서 무선센서네트워크에 있어서 가장 중요하고 기본적인 요소는 환경 정보를 수집하고 이를 사용자 응용시스템에 전송하는 센서노드 기술이다. 기술의 발전에 따라 센서노드는 점점 소형화 되고 지능화 되어 그 응용범위를 넓혀가고 있다. 특히 이식형 센서노드 기술은 인체나 가축의 체내에 이식되어 질병을 감시하고 치료하는데 사용됨으로써 무선센서네트워크의 미래 발전 방향을 제시한다. 본고에서는 가축의 체온을 실시간으로 감시할 수 있는 이식형 무선 센서노드를 설계하였다. 또한, 실시간 생체 감시 시스템 구현을 위한 추가적인 고려사항에 대하여 논하였다.

• 센서학회지
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• 제30권3호
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• pp.170-174
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• 2021

As the rising attention to the medical and healthcare issue, Bio-MEMS (Micro electro mechanical systems) platform such as bio sensor, cell culture system, and microfluidics device has been studied extensively. Bio-MEMS platform mostly has high resolution structure made by biocompatible material such as polydimethylsiloxane (PDMS). In addition, three dimension structure has been applied to the bio-MEMS. Lithography can be used to fabricate complex structure by multiple process, however, non-rectangular cross section can be implemented by introducing optical apparatus to lithography technic. X-ray lithography can be used even for sub-micron scale. Here in, we demonstrated lines with round shape cross section using the tilted gold absorber which was deposited on the oblique structure as the X-ray mask. This structure was used as a mold for PDMS. Molded PDMS was applied to the cell culture platform. Moreover, molded PDMS was bonded to flat PDMS to utilize to the sub-micro channel. This work has potential to the large area bio-MEMS.

• 한국인터넷방송통신학회논문지
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• 제22권2호
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• pp.129-134
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• 2022

버섯형 이중 격자 구조의 공진 바이오센서가 TE 편광 하의 근적외선 (NIR) 파장 범위에서 동작하도록 설계되었다. 정확한 MTLT (modal transmission-line theory)를 적용하여 광학적 특성을 결정하고, 격자 구조의 기하학적 매개변수를 변경하여 격자 구조의 반사 공진을 분석하였다. 수치 해석적 분석 결과, 단일층 격자 구조에서는 발생하지 않는 여기된 날카로운 Fano 공명 (FR)이 발생하였다. 설계된 구조에서 FR의 발생을 입증하기 위하여 이중 격자의 구조 매개변수와 반사 스펙트럼 사이의 관계를 자세하게 조사하였다. 제안된 구조를 기반으로 잠재적 감도가 112.9~214.3 deg/RIU, 그리고 447 nm/RIU인 광 바이오센서가 설계되었다. 제안된 버섯형 구조는 광범위한 응용 분야를 가진 광바이오센서 설계에 대한 좋은 표본으로 이용할 수 있다.

• JSTS:Journal of Semiconductor Technology and Science
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• 제13권4호
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• pp.355-360
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• 2013

A wireless intraocular (IOP) pressure sensor based on micro electro mechanical system (MEMS) technology is proposed. The proposed IOP sensor uses variable inductance according to the external pressure. The proposed sensor is composed of two flexible membranes: a ferrite bottom part, an inductor, and a capacitor. The inductance of the sensor varies according to the external pressure. The resonance frequency of the sensor is also varied, and this frequency is detected using an external coil. The external coil is designed with an FR-4 printed circuit board. The feasibility of the proposed sensor structure using variable inductance to detect the external pressure is successfully demonstrated.

• Journal of Communications and Networks
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• 제17권5호
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• pp.506-516
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• 2015

Wireless sensor networks (WSNs) are generally comprised of densely deployed sensor nodes, which results in highly redundant sensor data transmissions and energy waste. Since the sensor nodes depend on batteries for energy, previous studies have focused on designing energy-efficient medium access control (MAC) protocols to extend the network lifetime. However, the energy-efficient protocols induce an extra end-to-end delay, and therefore recent increase in focus on WSNs has led to timely and reliable communication protocols for mission-critical applications. In this paper, we propose an energy efficient and delay guaranteeing node scheduling scheme inspired by biological systems, which have gained considerable attention as a computing and problem solving technique.With the identification of analogies between cellular signaling systems and WSN systems, we formulate a new mathematical model that considers the networking challenges of WSNs. The proposed bio-inspired algorithm determines the state of the sensor node, as required by each application and as determined by the local environmental conditions and the states of the adjacent nodes. A control analysis shows that the proposed bio-inspired scheme guarantees the system stability by controlling the parameters of each node. Simulation results also indicate that the proposed scheme provides significant energy savings, as well as reliable delay guarantees by controlling the states of the sensor nodes.

• 대한화학회지
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• 제34권6호
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• pp.622-628
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• 1990

장미 구성요소 중 꽃잎 부분을 $NH_3$ 감응센서에 고정시켜서 글루타민 조직센서를 제조하여 pH, 완충용액, 조직 양 및 여러 가지 방해물질의 영향과 전극의 수명 등에 관하여 조사하였다. 그 결과 37$^{\circ}C$에서 pH 7.8, 0.2M 인산완충용액을 사용하였을 때, $8.0 {\times} 10^{-4}$ ∼$5.0 {\times} 10^{-2}$ M 글루타민 직선범위와 52 mV/decade의 감응기울기를 나타내었다. 이 때 사용한 조직 양은 50 mg이었다. 본 센서는 선택성이 탁월한 것으로 나타났다. 이 센서를 장미의 다른 구성요소와 비교하였다. 실제 글루타민의 정량에 유용하게 사용될 것으로 나타났다.