• 제목/요약/키워드: Benign laryngeal lesions

검색결과 25건 처리시간 0.021초

양성 성대 질환 환자의 후두 미세 수술 전후 음성 장애 지수 및 음성 분석의 유용성 (Validity of Voice Handicap Index and Voice Analysis following Laryngeal Microsurgery for Benign Vocal Cord Lesions)

  • 박영학;이정학;주영훈;박성신;방충일;김민식;조승호
    • 대한후두음성언어의학회지
    • /
    • 제16권1호
    • /
    • pp.23-27
    • /
    • 2005
  • Background and Objectives : Voice disorders can cause problems in patients with benign vocal cord lesions emotionally, physically, economically and functionally. Neither subjective nor objective voice examinations can evaluate such factors adequately. The Voice Handicap Index (VHI) subjectively evaluates voice disorders in terms of physical, functional, emotional factors and measures the patient's perception of the impact of voice disorder. The purpose of this study is to evaluate the usefulness of VHI in the patients with benign vocal cord lesions. Materials and Method : The authors evaluated 37 patients who experienced laryngeal microsurgery for benign vocal cord lesions from september 2003 to August 2004. The VHI was used to measure the postoperative changes of the patient's perception and acoustic analysis and aerodynamic tests were also done. Statistical analysis was done using paired t-test and Pearson's correlation. Results : The VHI scores showed statistically significant reductions postoperatively. In acoustic analysis, jitter and shimmer had statistically significant reductions after surgery but noise-to-harmonics ratio did not. A statistically significant change in the average MFR and MPT perioperatively was found. The relationship between VHI and acoustic, aerodynamic analysis attained statistical significance. Conclusion : The VHI is a useful assessment tool to monitor the patient's self-perception of voice change after the surgery of benign vocal cord lesions. The VHI measurement, when combined with acoustic and aerodynamic analyses, will be helpful in comparing functional outcomes after voice surgery.

  • PDF

후두암의 레이저 수술 (Treatment of Laryngeal Carcinomas by Laser Surgery)

  • 이동욱;김광현
    • 대한기관식도과학회지
    • /
    • 제6권2호
    • /
    • pp.172-176
    • /
    • 2000
  • Background and Objectives: The treatment of laryngeal carcinoma is not settled to date and surgeons have used lasers for a variety of benign and malignant lesions in the larynx with good success. The aim of this study is to evaluate the potential role of laser surgery for laryngeal carcinoma. Materials and Methods : Medical records from patients who had undergone laser surgery for laryngeal carcinoma at Seoul National University Hospital between January 1988 3nd December 1998 were reviewed retrospectively. Results : A total of 47 patients were seen during that period and their mean follow-up length was 29 months. Their local control rate was 91% (94% for glottic T1, 60% for glottic T2, 50% for supraglottic T1 and 100% for supraglottic T2). The cure rate after laser surgery with or without postoperative radiotherapy was 87% and 6 of 47 patients showed local or regional recurrences. For those 6 patients, neck dissection, partial or total laryngectomy with or without postoperative RT were conducted and they were all followed up without evidence of disease. All 47 patients who had undergone laser surgery for laryngeal squamous cell carcinoma were followed up with NED and their larynx preservation rate was 96%. Conclusion: This study demonstrates the oncologic validity of laser surgery to the treatment of unadvanced laryngeal carcinoma. However, strict case selection is needed to avoid locoregional recurrences and consequent salvage operations.

  • PDF

술 후 재발한 염증성 성대 병변의 임상 양상 (Clinical Analysis of Recurrence in Inflammatory Laryngeal Disease after Laryngomicrosurgery)

  • 김영선;김진호;박문규;유홍균;오준환;최종욱
    • 대한후두음성언어의학회지
    • /
    • 제11권1호
    • /
    • pp.28-31
    • /
    • 2000
  • Microscopic surgery of the larynx normally have a low recurrence rate. However, once they do recur, it is uneasy to manage recurrent diseases. Recurrence is often the result of inappropriate postoperative care and voice management. Out of the 764 patients operated for benign inflammatory laryngeal diseases, we have conducted a clinical analysis of 54 cases who have had at least one episode of recurrence after the initial treatment with laryngomicrosurgery (7.1% of recurrence rate). High risk groups for recurrence were determined, and they were related to cigarette smoking, alcohol intake, laryngopharyngeal reflux. From our experience and literature review, we conclude that pre- and postoperative patient education concerning these risk factors and voice usage Is of critical need to prevent recurrence of inflammatory laryngeal lesions after laryngomicrosurgery.

  • PDF

후두 편평상피의 전암성 및 악성병변에서 화상분석기를 이용한 DNA 배수성검사와 Ki-67 항체 양성세포의 분석에 관한 연구 (Study on DNA Content and Ki-67 Antibody Expression by Means of Image Analyzer for the Benign and Malignant Lesions of the Larynx)

  • 주형로;이선희;최종욱;김인선
    • 대한기관식도과학회:학술대회논문집
    • /
    • 대한기관식도과학회 1993년도 제27차 학술대회 초록집
    • /
    • pp.89-89
    • /
    • 1993
  • 후두의 상피세포에서 발생하는 질환중 전암성병변은 이형성(dysplasia)과 상피내암(carcinoma in situ)등이 있으며, 이들은 진행하게되면 침윤성 악성병변으로 전환하게 된다. 따라서 전암성 병변의 정도를 정확히 구분 및 파악함으로써 침윤성 암종으로의 전환여부를 미리 예견한다는 것은 악성 후두질환의 병태파악 및 예방에 중요한 역할을 차지한다. 이에 저자들은 최근 후두경하에 절제생검을 시행한 26례(침윤성 편평상피세포암 14례, 상피증식증 5례, 성대결절 7례)를 대상으로, 22례에서는 생검조직을 touch imprint법으로 도말하여 Feulgen염색한 후 CAS 200 화상분석기로 DNA함량분석을 시행하였고, 전례에 대하여 파라핀 포매조직에서 Ki-67 단크론성 항체(M1B1)를 이용하여 면역효소염색을 시행한 후 화상분석기로 양성표현율을 측정분석하여 다음과 같은 결과를 얻었다. 1) Ki-67 양성표현율은 침윤성 암종에서 31.65$\pm$11.59%, 상피증식증에서는 20.14$\pm$3.38%, 성대결절에서는 11.66$\pm$3.02%이었다. 2) 핵산지수(DNA index)는 침윤성 암종의 경우 비배수성이 10례 중 7례(70%), 상피증식증에서는 5례중 2례(40%), 성대결절에서는 7례 모두 이배수성을 보였다. 3) DNA함량분석에서 5기와 G2/M기를 합한 증식지수(PI)는 침윤성 암종에서 23.42$\pm$11.33%, 상피증식증에서는 13.09$\pm$10.90%, 성대결절에서는 4.50$\pm$1.19%로 침윤성 암종에서 가장 높았다. 이상의 성적에서 성대의 생검조직과 같은 미세조직으로부터도 DNA함량검사와 함께 Ki-67 양성표현율을 측정함으로써 전암성병변의 악성화 가능성 정도를 예견할 수 있었으며, 악성종양 환자의 예후판정에 도움을 얻을 수 있으리라 생각된다.

  • PDF

Elevated Neutrophil-to-Lymphocyte Ratio in Squamous Cell Carcinoma of Larynx Compared to Benign and Precancerous Laryngeal Lesions

  • Kum, Rauf Oguzhan;Ozcan, Muge;Baklaci, Deniz;Kum, Nurcan Yurtsever;Yilmaz, Yavuz Fuat;Gungor, Volkan;Unal, Adnan
    • Asian Pacific Journal of Cancer Prevention
    • /
    • 제15권17호
    • /
    • pp.7351-7355
    • /
    • 2014
  • Background: Laryngeal carcinogenesis is a multifactorial process that has not been fully elucidated. Despite extensive research, reliable markers with diagnostic and prognostic value are still lacking. It was recently reported that an elevated preoperative neutrophil-to-lymphocyte ratio (NLR) may correlate with an increased risk of recurrence, tumor aggressiveness and poorer prognosis in various malignancies. The aim of this study was to examine whether NLR could be used as an inflammatory marker to differentiate laryngeal squamous cell carcinoma (LSCC) patients from benign laryngeal lesion (BLL) and precancerous laryngeal lesion (PLL) patients. Materials and Methods: This retrospective study was performed on 209 patients admitted to a tertiary referral center with laryngeal lesions and undergoing biopsies to establish their histopathological diagnosis. We reviewed the patient files for their clinical, histopathological and laboratory data. The patients were divided into three groups according to their histopathological findings, as BLL, PLL and LSCC groups. The patients in the PLL group were also divided into three subgroups as mild, moderate and severe dysplasia/carcinoma in situ (CIS) subgroups. The groups were compared for NLR and the other laboratory data. Results: The mean NLRs of the BLL, PLL and the LSCC groups were $2.12{\pm}0.86$, $2.32{\pm}0.68$ and $3.46{\pm}1.51$, respectively, and the difference was statistically significant (p=0.001). The mean NLRs of the patients with PLL and LSCC were significantly higher than the patients with BLL (p=0.031 and p=0.001, respectively). The mean NLRs were similar among mild dysplasia, moderate dysplasia and severe dysplasia / CIS groups (p>0.05). Conclusions: To our knowledge, this is the first study investigating NLR in BLL, PLL and LSCC. NLR is an inexpensive, reproducible and widely available blood test, and could be a useful inflammatory marker to differentiate LSCC from BLL and PLL.

후두 양성점막 병변의 수술적 치료 (Surgery of Benign Laryngeal Mucosal Lesions)

  • 진성민
    • 대한후두음성언어의학회지
    • /
    • 제24권2호
    • /
    • pp.83-87
    • /
    • 2013
  • The term "phonosurgery," coined in the early 1960s, refers to surgical procedures that maintain, restore, or enhance the human voice. Phonosurgery includes phonomicrosurgery (endoscopic microsurgery of the vocal folds), laryngoplastic phonosurgery (open-neck surgery that restructures the cartilaginous framework of the larynx and the soft tissues), laryngeal injection (injection of medications as well as synthetic and organic biologic substances), and reinnervation of the larynx. Phonomicrosurgery is a means of maximally preserving the layered microstructure of the vocal fold, that is, the epithelium and lamina propria. The purpose of the surgery is usually to improve the vibratory characteristics of the layered microstructure of the vocal folds. Phonomicrosurgery has developed from convergence of microlaryngoscopic surgical technique theory and the mucosal wave theory of laryngeal sound production. Improvements in technology (i.e., laryngoscopes, handled instruments, and lasers), which in part arise from developments in more frequently performed minimally invasive surgical procedures, will probably facilitate the next generation of procedural innovations. The best methods of optimizing phonosurgical outcomes include making an accurate diagnosis, completing a comprehensive voice evaluation, providing sufficient preoperative therapy, carefully selecting patients to undergo phonomicrosurgical procedures, and requiring sufficient postoperative rest and therapy. Phonomicrosurgery will continue to evolve as a result of the interdependent collaboration of surgeons with voice scientists, speech pathologist, and other voice professionals.

  • PDF

성대 낭종 내부에 발생한 후두 편평세포암종 (Squamous Cell Carcinoma of the Larynx Arising in the Intracordal Cyst)

  • 이선규;송민정;은영규;이영찬
    • 대한후두음성언어의학회지
    • /
    • 제32권1호
    • /
    • pp.48-50
    • /
    • 2021
  • More than half of patients presenting with hoarseness show benign vocal cord changes. However, in rare cases with benign mucosal lesions, it can be diagnosed as a malignant disease after histopathological examination. A 53-year-old man with a 30-pack-year smoking history was admitted for the evaluation of hoarseness, and using a laryngoscope, an enclosed, sac-like cystic lesion was detected on the midpoint of the right true vocal cord. The cystic lesion was deemed to be an intracordal cyst and treated with laryngeal microsurgery. However, pathological findings showed squamous cell carcinoma of the larynx arising in the intracordal cyst, which is exceptionally rare. Therefore, even if a benign lesion is initially suspected, a biopsy must be performed on a patient with smoking history to confirm the diagnosis. In conclusion, we report a case of squamous cell carcinoma of the larynx arising in the intracordal cyst.

음성장애에 대한 임상적고찰 (Clinical Observation on Voice Disorder)

  • 이종원
    • 대한기관식도과학회:학술대회논문집
    • /
    • 대한기관식도과학회 1979년도 제13차 학술대회 연제순서 및 초록
    • /
    • pp.7.2-8
    • /
    • 1979
  • 음성외과는 발성기능를 취급하는 기능외과이기 때문에 수술적응의 결정 수술효과의 판정 수술성적의 비교를 위하여 발성기능의 검사가 필요하다. 청력을 취급하는 수술에서 청력검사가 필요한 것과 같다. 연자는 구유미대학 이비인후과를 방문한 각종후두환자(56례 즉Recurrent laryngeal nerve paralysis, polyp. polipoid vocal cord. sulcus vocalis, Laryngeal cancer, Benign mass, Epitherial hypertrophy. 등에서 발성지적시간, 폐활량/담성지적시간, 평균호기유율 및 후두 Stroboscopy 검사를 시행하여 다음과같은 결과를 얻었다. 1) 성대의 편측성병변은 35례(62.5%)이고 양측성병변은 21례(37.5%)로 편측성병변이 많았다. 2) 성별로는 남성이 39례(69.8%) 여성이 17례(30.2%)로 남성이 많았다. 3) 발성지적시간은 10초이하가 26례(46.4%) 10초이상이 30례(53.6%)이였다. 4) 폐활양/발성지적시간은 300m1/sec이하가 33례(58.9%) 300m1/sec이상이 23례(41.1%)이였다. 5) 평균호기류율은 300m1/sec이하가 37례(66.1%)300ml/sec 이상이 19례(33.9%)이였다. 6) 후두 stroboscopy 검사에서 성대의 대칭성, 규칙성, 진폭, 점막파동 및 성문패쇄에 대해서 관찰하였다. 7) 후두수술전후의 음성검사와 stroboscopy 검사의 비교는 수술후의 성적이 매우 좋다.

  • PDF

복합화학요법에 반응한 악성 사구체 종양 1예 (A Case Report of Malignant Glomus Tumor Responding to Combination Chemotherapy)

  • 이상윤;최인실;박숙련;김도연;김광현;김노경;허대석
    • 대한두경부종양학회지
    • /
    • 제18권2호
    • /
    • pp.219-222
    • /
    • 2002
  • Malignant glomus tumor is a very rare disease originating from the paraganglia system through the body. Glomus tumor, also known as paraganglioma, usually are considered benign, and arises in a variety of head and neck locations, most of which include the carotid body, the vagus nerve, and the jugulotympanic area. The most widely accepted management of benign glomus tumor is surgical extiration. Here, we report a case of recurrent laryngeal glomus tumor which is proven malignant and metastatic to the brain and the lungs. We have treated the patient with combination chemotherapy and radiation to the brain, the result of which is partial response in terms of decreased size of metastatic lung lesions.

기관절개술과 후두절개술로 치료한 거대 성문하 용종 1예 (Huge Subglottic Polyp Treated with Tracheotomy and Laryngofissure)

  • 홍용태;여차동;홍기환
    • 대한후두음성언어의학회지
    • /
    • 제28권1호
    • /
    • pp.52-54
    • /
    • 2017
  • Vocal polyps are benign laryngeal lesions which arise from the Reinke's space abd hoarseness is the most common symptom. However, airway compromised is rarely presented in the vocal polyp. A rare case of large subglottic polyp causing dyspnea is reported. Tracheostomy was performed under local anesthesia and then the mass was resected under general anesthesia using a laryngofissure approach. The dyspnea and hoarseness disappeared after surgery immediately. The histopathological findings indicated a diagnosis of vocal cord polyp with chronic inflammatiuon. We consider that tracheostomy is the safest and most useful procedure to guarantee the upper airway in cases of large vocal polyp showing dyspnea. We hereby report a case of huge subglottic polyp in which a tracheostomy and laryngofissure was required for removing the subglottic mass successfully.

  • PDF