• 제목/요약/키워드: Bc1-2

검색결과 836건 처리시간 0.027초

MPEG 오디오 부호화 기술 분석 (Analysis of MPEG Audio Coding Technology)

  • 홍진우
    • 한국음향학회:학술대회논문집
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    • 한국음향학회 1998년도 학술발표대회 논문집 제17권 1호
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    • pp.249-254
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    • 1998
  • MPEG 오디오 그룹에서는 오디오 부호화 기술의 국제 표준으로 MPEG-1 오디오, MPEG-2 오디오 BC, MPEG-2 AAC의 규격 제정을 완료하였고, 현재 MPEG-4 오디오 및 MPEG-7 오디오의 국제 표준을 제정하고 있다. 본 논문에서는 이들 표준에 대한 요구 기능 및 기술 특징을 분석하고, 각각의 표준에 대한 응용분야와 향후의 계획에 대하여 기술한다.

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Molecular Characterization of a ${\beta}$-1,4-Endoglucanase Gene from Bacillus subtilis H12

  • Oh, Jin-Hwan;Cha, Jeong-Ah;Yoon, Min-Ho
    • Applied Biological Chemistry
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    • 제51권4호
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    • pp.299-304
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    • 2008
  • A ${\beta}$-1,4-endoglucanase gene from Bacillus subtilis H12 was cloned into Escherichia coli JM109 (pBC8) and sequenced. The endoglucanase gene with an insert DNA of 2.5 kb possessed an open reading frame of 1,500 bp encoding a mature protein of 499 amino acids with a calculated molecular mass of 55 kDa. The deduced amino acid sequence showed similarity to those of the known neutral cellulase genes of B. subtilis PAP115 (99.2%) and BSE616 (97.8%), as well as the alkaline gene of Bacillus sp. N4 (55.1%). The endoglucanase activity expressed by E. coli (pBC8) was localized in the periplasmic fraction (80%) and the cytoplasmic fraction (20%). An endoglucanase was purified from the periplasmic fraction by performing gel filtration and anion exchange chromatography. The molecular weight of the purified enzyme was estimated to be 31 kDa by SDS-PAGE, and the maximum activity occurred at pH 7 and $40^{\circ}C$. The enzyme easily hydrolyzed soluble substrates such as carboxymethyl cellulose and barely ${\beta}$-glucan, whereas the sigmacell and xylan, the known insoluble substrates, were not entirely hydrolyzed.

Development of a Segregating Population with Biological Efficiency in Agaricus bisporus

  • Oh, Youn-Lee;Sonnenberg, Anton S.M.;Baars, Johan J.P.;Jang, Kab-Yeul;Oh, Min ji;Im, Ji-Hoon;Kong, Won-Sik
    • 한국균학회지
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    • 제45권4호
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    • pp.328-335
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    • 2017
  • In this study, we made a population with high biological efficiency (BE) to investigate the complex genetic architecture of yield-related traits in Agaricus bisporus. MB-013 crossed between bisp 015-p2 and bisp 034-p2, had high BE. Additionally MB-013 was an intervarietal hybrid that intercrosses with A. bisporus var. burnettii, bisp 015, and A. bisporus var. bisporus, bisp 034. One hundred and seventy homokaryons were selected using the cleaved amplified polymorphic sequence (CAPS) markers (PIN primer/HaeIII) from 300 single spore isolates (SSIs). One hundred $BC_1F_1$ hybrids were obtained by crossing the homokaryons of MB-013 with bisp15-p1. The population of 100 BC1F1 hybrids is suitable for analyses of BE.

근거리 레이더용 CMOS 저전력 교차 결합 전압 제어 발진기 설계 및 제작 (Design and Fabrication of CMOS Low-Power Cross-Coupled Voltage Controlled Oscillators for a Short Range Radar)

  • 김락영;김동욱
    • 한국전자파학회논문지
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    • 제21권6호
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    • pp.591-600
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    • 2010
  • 본 논문에서는 TSMC 0.13 ${\mu}m$ CMOS 공정을 사용하여 3가지 종류의 근거리 레이더용 저전력 교차 결합 전압 제어 발진기를 설계, 제작하였다. 기본적인 교차 결합 전압 제어 발진기는 24.1 GHz를 중심으로 발진하도록 설계되었고, 이를 기본으로 저전력 동작을 위한 subthreshold 발진기가 설계되었다. 특히 큰 트랜지스터를 사용해야 하는 subthreshold 발진기에서 기생 캐패시터에 의해 발진 주파수가 낮아지는 문제점을 개선하기 위해 이중 공진 회로 구조를 발진기에 사용하는 것이 시도되었다. 제작된 CMOS 전압 제어 발진기는 종류에 따라 1 MHz offset 주파수에서 -101~-103.5 dBc/㎐의 위상 잡음, -11.85~-15.33 dBm의 출력 전력, 그리고 475~852 MHz의 주파수 조정 범위들을 보였다. 전력 소모 측면에서는 기본적인 발진기가 5.6 mW를 사용하였고, 저 전력 subthreshold 회로는 3.3 mW를 사용하였다. 이중 공진 회로 구조의 subthreshold 발진기는 기본 발진기와 유사한 주파수 조정 범위를 유지하면서 상대적으로 작은 전력을 소모하고 개선된 위상 잡음 특성을 보였으며, 1 mW DC 전력 기준의 figure-of-merit(FOM)이 약 3 dB 가량 개선되어 -185.2 dBc의 값을 가졌다.

A Study on the DNA Polymorphisms at $\beta$fibrinogen Loci and Plasma Fibrinogen Concentration

  • Lee, Mi-Hwa;Ohrr, Hee-Choul;Song, Kyung-Soon
    • 대한의생명과학회지
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    • 제7권3호
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    • pp.151-159
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    • 2001
  • Many prospective studies have confirmed the predictive value of plasma fibrinogen levels for vascular diseases, including ischemic heart disease. Several polymorphisms of the $\beta$fibrinogen gene have been investigated in relation to plasma fibrinogen levels. The blood samples for DNA were collected from 109 healthy Koreans who have no relationship by blood (67 males and 42 females) in due consideration of some other factors such as gender, age, and smoking status. Four polymorphisms of the $\beta$fibrinogen gene that consist of HaeIII, AluI, MaII and BcII restriction fragment length polymorphisms (RFLPs) were investigated to examine the associations between RFLPs and plasma fibrinogen levels. In conclusion, the significant associations between HaeIII, AluI, MnII RFLPs(H$_1$H$_2$, M$_1$M$_2$, $A_1$A$_2$) and the concentration of plasma fibrinogen were shown by the smokers as well as by the old people more than 50, whereas the association between BcII and plasma fibrinogen were shown no connection with the status of age and smoking. The concentration of plasma fibrinogen was significantly shown higher by the old people ($\geqq$50) by the younger people ($\leqq$49) in male and also higher by the smokers than by the nonsmokers.

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The Neutrophil to Lymphocyte Ratio has a High Negative Predictive Value for Pathologic Complete Response in Locally Advanced Breast Cancer Patients Receiving Neoadjuvant Chemotherapy

  • Eryilmaz, Melek Karakurt;Mutlu, Hasan;Salim, Derya Kivrak;Musri, Fatma Yalcin;Tural, Deniz;Coskun, Hasan Senol
    • Asian Pacific Journal of Cancer Prevention
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    • 제15권18호
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    • pp.7737-7740
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    • 2014
  • Background: The neutrophil-to-lymphocyte ratio (NLR) is a strong predictor of mortality in patients with pancreatic, colorectal, lung, gastric cancer and renal cell carcinoma. The aim of this study was to determine the relationship between pathological complete response (pCR) and pretreatment NLR values in locally advanced breast cancer (BC) patients receiving neoadjuvant chemotherapy (NACT). Materials and Methods: Datawere collected retrospectively from the Akdeniz University School of Medicine Database for locally advanced BC patients treated with NACT between January 2000-December 2013. Results: A total of 78 patients were analyzed. Sixteen (20%) patients achieved pCR. Estrogen receptor (ER) positivity was lower in pCR+ than pCR-cases (p=0.011). The median NLR values were similar in both arms. The optimum NLR cut-off point for BC patients with PCR+ was 2.33 (AUC:0.544, 95%CI [0.401-0.688], p=0.586) with sensitivity, specificity, positive predictive value and negative predictive value (NPV) of 50%, 51,6%, 21,1%, and 80%, respectively. Conclusions: This study showed no relationship between the pCR and pretreatment NLR values. Because of a considerable high NPV, in the patients with higher NLR who had luminal type BC in which pCR is lower after NACT, such treatment may not be recommended.

Quality Protein Maize 육성계통의 지방산 및 아미노산 특성 (Characterization on Fatty Acids and Amino Acids of Quality Protein Maize Lines)

  • 김선림;손범영;정태욱;문현귀;손종록
    • 한국작물학회지
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    • 제51권5호
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    • pp.458-465
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    • 2006
  • Quality protein maize(QPM) 육성계통의 화학적 특성과 지방산 및 아미노산 조성을 검토하기 위하여 KS5/QPM 계통의 $BC_{1}F_{2}$ 및 KS135/QPM 계통의 $BC_{1}F_{2}$ 자식계통을 대상으로 opaque-2 specific micro-satellite marker인 umc1066를 사용하여 QPM 26계통을 선발하고 non-QPM 34계통을 공시하여 얻어진 결과를 요약하면 다음과 같다. 1. QPM계통은 non-QPM계통에 비하여 지방함량이 유의하게(p<0.05) 증가되었으나 단백질함량은 통계적 유의차가 없었다. 2. QPM 계통과 non-QPM 계통 모두 linoleic acid(Cl8:2)의 조성비가 가장 높고 oleic acid(Cl8:1), palmitic acid(Cl6:0), linolenic acid(Cl8:3), stearic acid(Cl8:0)의 순으로 지방산 조성비가 높았다. 3. QPM 계통은 non-QPM 계통에 비하여 포화지방산의 비율이 다소 높고 불포화지방산의 비율은 non-QPM 계통에 비하여 조성비가 낮았으나 통계적 유의성은 없었다. 4. QPM 계통은 non-QPM 계통에 비하여 lysine의 조성 비율이 높고 황함유 아미노산(cystine, methionine)의 비율이 증가되었다. 5. QPM 계통의 필수아미노산의 조성비율은 28.1%였고 non-QPM 계통은 27.1%로 QPM 계통이 영양학적인 면에서 유리한 것으로 판단되었다.

Feedforward 선형화 기법을 이용한 IMT-2000용 MCPA의 설계 및 제작 (The Design and Implementation of MCPA for IMT-2000 using Feedforward Linearization)

  • 노상연;정성찬;정종한;박명석;박천석
    • 한국전자파학회논문지
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    • 제12권1호
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    • pp.99-106
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    • 2001
  • 본 논문에서는 선형화 특성이 우수하고, 대역폭이 넓은 feedforward 선형화 기법을 이용하여 IMT-2000용 1-Watt 급 증폭기를 설계 제작하였다. Feedforward는 외부환경(온도, 입력 전력 레벨, 시간 등)의 변화에 민감하므로 마이크로컨트롤러를 이용하여 이를 제어하였다. 35dB 의 이득과 40dBm의 최고전력을 갖는 주증폭기를 설계하였고, 각 루프의 신호를 상쇄하기 위해서 반사형 가변감쇄기와 위상변화기를 사용하였다. 2.11 2.17GHz 대역에서 측정 결과 신호루프에서 주신호를 35dB이상 상쇄하였으며, 오차루프에서 30dB 이상 오차신호를 상쇄하여 60dBc 이상의 선형화 특성을 얻을 수 있었다.

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기후변화를 고려한 농촌지역 그린빌리지의 태양에너지 활용에 관한 경제성 분석 (Economic Analysis of Rural Green-Village Planning with Solar Energy considering Climate Change)

  • 김대식;왕영두
    • 농촌계획
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    • 제19권3호
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    • pp.25-36
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    • 2013
  • This study aims to perform the economic analysis to the use of solar power facilities in rural villages considering the climate change scenario. IPCC climate change scenarios in the recently adopted the RCP scenarios (RCP8.5, RCP6.5, RCP4.5, RCP2.6) was used. By RCP scenarios, solar radiation, depending on the scenario in 2100, respectively, 3.6%, 2.5%, 1.9%, 1.1% was assumed to increase. From the economic analysis(payback period is 25 year) on 8 points of each province, in all cases of normal data and four RCP scenarios, at all points analyzed were NPV indicate a negative, BC ratio less than 1.0, respectively. In the case of Mokpo, Chunnam RCP8.5, BC ratio were found to be up to a 0.92, followed by 0.89 in the case of RCP8.5 in Jinju, Kyungnam shows, while the minimum was in Jeju. BC ratio is 1.0 or bigger, in order for the normal solar radiation data in Mokpo, Chonnam was the minimum that it takes 37 years. Similarly, in the case of RCP scenarios, 30 years in Mokpo, Chonnam RCP8.5 and 31 years in the cases of Jinju, Kyungnam and Jeonju, Cheonbuk RCP8.5 were analyzed. It was analyzed that RCP8.5 has the highest value. BC analysis models for each of the factors, the results of the sensitivity analysis, the initial installation costs, electricity sales price, discount rate in the order of economy showed higher sensitivity, and the rest factors showed lower changes. Although there are some differences of solar radiation by region, but in Korea most facilities in rural areas, the use of solar power was considered to be economical enough, considering change of several factors with high sensitivity, such as increasing of government subsidies for the solar power installation of the facility, rising oil prices due to a rise in electricity sales price, and a change in discount rate. In particular, when considering climate change scenarios, the use of solar energy for rural areas of the judgment that there was more economical.

Outcome of Breast Cancer Screening: A Lebanese Single Institution Experience

  • Kourie, Hampig Raphael;Daher, Alain;Matar, Dany;Antoun, Joelle;Salloum, Lony;Kattan, Joseph
    • Asian Pacific Journal of Cancer Prevention
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    • 제15권21호
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    • pp.9471-9473
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    • 2014
  • Background: Since 2002, from October till December of each year, the Lebanese Ministry of Public Health conducts a mammogram based breast cancer screening campaign in the whole country for women over 40 years of age. These mammograms are performed free of charge in governmental hospitals or for reduced fees in private hospitals. The aim of this study is to analyze the direct impact of this campaign on cancer detection and subsequent treatment. Materials and Methods: Radiologic records of women screened with a mammogram during the campaign period from October till December 2012 at Saint Joseph Hospital, Baouchrieh, Beirut, were reviewed. Results of mammograms were reported using the ACR score. Women with ACR score ${\geq}4$ were tracked and investigated. Results: 900 screening mammograms were performed; median age was 55.2 years (range:31-81 years). Some 826 (91.8%) had an ACR score of ${\leq}2$; 66 (7.3%) an ACR =3 and only 8 (0.89%) an ACR=4. Thus, less than 1% (8/900) of all screened women were considered at high risk and needed a close follow-up. Among these 8 women, 4 underwent surgery for an early breast cancer, one had synchronous metastatic breast cancer and two were lost to follow-up. Conclusions: To coclude, Among 900-screened women for BC, less than 1 % (8 out of 900) were at high risk of hiding a BC (ACR=4), half of them benefited from early therapy (4 women out of 900) and one was a false positive. Larger studies on national level should be accomplished to have a complete data on breast cancer screening in Lebanon. The results of these studies can affect the Lebanese health policy regarding BC.