• Journal of IKEEE
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• v.11 no.1 s.20
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• pp.15-23
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• 2007

This paper describes a dual frequency synthesizer designed in a 0.2$\mu$m CMOS technology for wireless LAN applications. The design is focused mainly on low-power characteristics. Power dissipation is minimized especially in VCO and prescaler design. The designed synthesizer includes all building blocks for elimination of external components, other than the crystal. Its operating frequency can be programmed by external data. It operates in the frequency range of 2.3GHz to 2.7GHz (RF) and 250MHz to 800MHz (IF) and consumes 5.14mA at 2.5GHz and 1.08mA at 0.5GHz from a 2.5V supply. The measured phase noise is -85dBc/Hz in-band and -105dBc/Hz at 1MHz offset at IF band. The die area is 1.7mm$\times$1.7mm.

• Asian Pacific Journal of Cancer Prevention
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• v.16 no.13
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• pp.5537-5540
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• 2015

Purpose: To research the association between pre-treatment elevated platelet count and clinicopathologic characteristics in breast cancer (BC), as well as explore the relationship between pre-treatment elevated platelet count and HER2 status and prognosis of BC patients. Materials and Methods: A retrospective cohort of BC patients who were newly diagnosed or treated by surgery only and had pathological detection results and platelet values in the Department of Oncology, the First Affiliated Hospital of Liaoning Medical College were enrolled from 1/1/2008 until 31/12/2009, and followed up until 31/12/2014. Age, thrombocyte parameters before chemotherapy and/or radiotherapy, immunohistochemical (IHM) indexes, and regional lymph node (LN) involvement and progression-free survival (PFS) were recorded. Results: A total of 447 eligible subjects were included in this research. As we analyzed, for HER2, positive and negative, the incidence rates of elevated platelet count were 25.8% and 14.7% (P<0.05). In the Cox proportional hazards model both variables were independent risk factors for BC (for HER2, OR, 0.592, 95% confidence interval, CI, 0.355 to 0.985, P=0.044;f or PLT, OR, 0.998, 95% CI, 0.996 to 1.000, P=0.042). For ER, PR, Ki67 and LN involvement, the differences were not statistically significant (P>0.05). Conclusions: In this research, pre-treatment elevated level of platelet count demostrated a significantrelationship with HER2 amplification/overexpression, and both variables significantly influenced the prognosis of BC. However, elevated platelet count did not exhibit any association with ER, PR, Ki67 and LN involvement.

• International Journal of Industrial Entomology and Biomaterials
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• v.3 no.2
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• pp.187-190
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• 2001

Inheritance pattern of resistance to Bombyx mori nuclear polyhedrosis virus (BmNPV) was studied in an Indian silkworm stock TX by single back-cross test method. The resistant parent ［TX］, susceptible parent ［HM］, their Fl, F2, and Fl progeny back-crossed to TX [BC(R)] and HM [BC(S)] were inoculated per os with a fixed concentration of BmNPV($0.5{\times}10^{th} PIB/ml$) on the first day of second stadium. The cumulative mortality was recorded until day $10^{\times}$ post-inoculation. The results show that the resistance to BmNPV in TX fellow mono Mendelian inheritance pattern. The resistance dominated over the susceptibility at Fl. At F2, the resistant and susceptible offspring segregated in 3:1 ratio whereas at BC(S), the resistant and susceptible offspring segregated in 1:1 ratio. The response of BC(R) was more or less like the resistant parent TX which confirms the involvement of a major dominant gene conferring resistance to BmNPV in TX. The possible mechanism of inheritance of resistance in TX is discussed.

• Current Research on Agriculture and Life Sciences
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• v.18
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• pp.9-17
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• 2000

In an effort to breed lines resistant to both bacterial wilt and Phytophthora blight, F5 and BC1F4, and F6 and BC1F5 generations of the crosses between the lines previously bred for resistance to Phytophthora blight ((16-2-2-3-2 = Phytophthora-resistant 'Kalmi', 19-1-3-7-1-1, 19-2-4-5-3-2 = Phytophthora-resistant 'Subi', Kim et al., 1996) and sources of resistance to bacterial wilt (KC350 = MC-4 or KC353 = PBC631, Kim et al., 1998) were evaluated for resistance to both bacterial wilt and to Phytophthora blight in 1999 and in 2000, respectively. Plants which were highly resistant to both bacterial wilt and Phytophthora blight were selected for development of the next generations.

• Journal of the Institute of Electronics Engineers of Korea TC
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• v.44 no.7 s.361
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• pp.7-11
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• 2007

This paper presents a multiband octa-phase LC VCO for SDR receiver. Four identical LC VCOs are connected by using series coupling transistor to obtain the octa-phase signal and low phase noise characteristic. For a multiband application, a band tuning circuit that consists of a switch capacitor circuit and two MOS varactors is proposed. As the MOS switch is on/off state, the frequency range will be varied. In addition, two varactors make the VCO be immune to process variation of the oscillation frequency. The VCO is designed in 0.18-um CMOS technology, consumes 12mA current from 1.8V supply voltage and operates with a frequency band from 885MHz to 1.342GHz (41% tuning range). As driving sub-harmonic mixer, the proposed VCO covers 3 standards(CDMA 2000 1x, WCDMA, WiBro). The measured phase noise is -105dBc@100kHz, -115dBc@1MHz, -130dBc@10MHz for CDMA 2000 1x, WCDMA, WiBro respectively.

• Journal of Preventive Medicine and Public Health
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• v.50 no.6
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• pp.401-410
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• 2017

Objectives: The purpose of this study was to examine the associations of childbirth, breastfeeding, and their interaction with breast cancer (BC) risk reduction, and to evaluate the heterogeneity in the BC risk reduction effects of these factors by menopause, hormone receptor (HR) status, and pathological subtype. Methods: BC patients aged 40+ from the Korean Breast Cancer Registry in 2004-2012 and controls from the Health Examinee cohort participants were included in this study after 1:1 matching (12 889 pairs) by age and enrollment year. BC risk according to childbirth, breast-feeding, and their interaction was calculated in logistic regression models using odds ratios (ORs) and 95% confidence intervals (CIs). Results: BC risk decreased with childbirth (3+ childbirths relative to 1 childbirth: OR, 0.66; 95% CI, 0.56 to 0.78 and OR, 0.80; 95% CI, 0.68 to 0.95 in postmenopausal and premenopausal women, respectively); and the degree of risk reduction by the number of children was heterogeneous according to menopausal status (p-heterogeneity=0.04), HR status (p-heterogeneity<0.001), and pathological subtype (p-heterogeneity<0.001); whereas breastfeeding for 1-12 months showed a heterogeneous association with BC risk according to menopausal status, with risk reduction only in premenopausal women (p-heterogeneity<0.05). The combination of 2 more childbirths and breastfeeding for ${\geq}13$ months had a much stronger BC risk reduction of 49% (OR, 0.51; 95% CI, 0.45 to 0.58). Conclusions: This study suggests that the combination of longer breastfeeding and more childbirths reduces BC risk more strongly, and that women who experience both 2 or more childbirths and breastfeed for ${\geq}13$ months can reduce their BC risk by about 50%.

• Journal of the Korean Society of Manufacturing Process Engineers
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• v.19 no.12
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• pp.42-48
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• 2020

Given the increasing interest in air pollution, several technologies to measure black carbon (BC) aerosol particles have been developed. As most BC aerosol particles are smaller than 1 ㎛, it is necessary to pre-separate the particles by size before a BC measuring instrument samples the aerosol particles. In this study, a miniature cyclone separator for portable BC measuring instruments was developed. A numerical approach was used to design the miniature cyclone separator with operating flow rates of 50, 100, or 150 mLPM, and then a prototype cyclone separator was manufactured for experimental validation. The numerical results of the cut-off size and pressure drop of the miniature cyclone separator agreed well with the experimental data. The cut-off sizes of the miniature cyclone separator were determined to be 2.9, 0.94, and 0.63 ㎛ for operating flow rates of 50, 100, and 150 mLPM, respectively. Thus, the miniature cyclone separator is suitable for use as a sampling inlet for the portable black carbon measuring instrument to sample BC aerosol or PM2.5 aerosol.

• Journal of Korean Society of Occupational and Environmental Hygiene
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• v.6 no.2
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• pp.209-221
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• 1996

The purpose of this study was to find a suitable cosolvent to $CS_2$ so that desorption efficiency can be improved for both polar and non-polar organic solvent mixtures collected on an activated charcoal tube. Cosolvents added to $CS_2$ include: DMF(N,N-dimethylformamide): $CS_2$ (v/v 1:99), DMF:$CS_2$(v/v 3:97), BC (butyl carbitol, 2-(2-butoxy ethoxy) ethanol):$CS_2$(v/v 1:99), and BC:$CS_2$(v/v 3:97)). The results obtained were as follows : 1. Comparing the desorption efficiency of $CS_2$ with those of $CS_2$ with 1, 3, 5 % DMF and 1, 3 % BC cosolvents for two different groups of charcoal tubes each containing 8 different polar and non-polar organic solvents with 3 different concentration levels, the desorption efficiencies of the cosolvent-added $CS_2$ increased significantly for all polar organic solvents regardless of concentration levels tested. For non-polar organic solvents, no noticeable improvement was detected except xylene and trichloroethylene. The desorption efficiency of xylene increased significantly while that of trichloroethylene increased significantly at the lowest concentration level tested. 2. Either 5 % DMF or 3 % BC was the most suitable cosolvent because the desorption efficiency for non-polar organic solvent mixtures was similar or slightly improved compared with that of $CS_2$, while those of for polar organic solvent mixtures were above 75 % except for cyclohexanone. 3. The smallest variations in desorption efficiency represented by the ratio calculated from the maximum to minimum desorption efficiency for all concentration levels tested were found when 3 % BC was used as a cosolvent. The above results indicate that the desorption efficiency of $CS_2$ particularly for polar organic solvent mixtures collected on a charcoal tube can be significantly improved by the use of cosolvents such as 5 % DMF or 3 % BC. A caution, however, is in order for selecting a cosolvent whenever the cosolvent itself is being used in the workplace or the impurities contained in the cosolvent may interfere with the analytical results. In addition, to improve desorption efficiencies for such organic solvents as cyclohexanone or ketones, it is recommended to use suitable collection and desorption media other than the traditional method of charcoal tube collection/$CS_2$ desorption.

• The Journal of The Korea Institute of Intelligent Transport Systems
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• v.4 no.2 s.7
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• pp.81-87
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• 2005

In this paper, a VCDRO(Voltage Control Dielectirc Resonator Oscillator) for signal source of doppler radar system is designed and fabricated. The proposed VCDRO is made with new tuning mechanism using CPW line. The coplanar waveguide of $\lambda_{g}$/2 in length with varactor diode is placed on the metallization side under the dielectric resonator and coupled to it. Tuning varactor diode is mounted at one end of the CPW. The proposed circuit tuned by a CPW allows one more varactor diode to be mounted on the optimized CPW, where a greater sensitivity of frequency tuning is needed. With varying the biasing voltage for the varactor diode from 0 V to 15 V, output frequency tuning of 12 MHz is obtained. The PLDRO exhibits output power of 16.5 dBm with phase noise in the phase locked state characteristic of -115 dBc/Hz at 100 Hz, -105 dBc/Hz at the 10 kHz, and -102 dBc/Hz at 1 Hz offset from 10.525 GHz , respectively.

• JSTS:Journal of Semiconductor Technology and Science
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• v.16 no.5
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• pp.535-541
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• 2016

A low phase noise META-VCO based-on meta-structure was designed using 65 nm CMOS process. We used a meta-structure to get good phase noise characteristics. The measured phase noises are -67.8 dBc/Hz, -96.37 dBc/Hz, and -107.37 dBc/Hz at 100 kHz, 1 MHz, and 10 MHz offset respectively. The META-VCO operates 8.45~8.77 GHz according to VCTRL, and the output power is -19.12 dBm. The power consumption is 28 mW with 1.2-V supply voltage. The calculated FOM is -140.76 dBc/Hz.