• Korean Journal of Clinical Laboratory Science
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• v.55 no.2
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• pp.105-112
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• 2023

Leucine-rich repeat kinase 2 (LRRK2) is known to play a crucial role in the pathophysiology of neurodegenerative disorders such as Parkinson's disease. LRRK2 is predominantly expressed in the lung as well as the brain. However, it is unclear whether LRRK2 expression correlates with the pathogenesis of lung squamous cell carcinoma (LUSC). This study analyzes the prognostic significance of LRRK2 in LUSC using the Kaplan-Meier plotter tool. High expression of LRRK2 is known to be associated with a bad prognosis in patients with LUSC. Patients with high LRRK2 expression, tumor mutational burden, high neoantigen load, and even gender correlation reportedly have the worse survival rates. In the gene expression profiling interactive analysis (GEPIA) database, the severity of pathogenesis in LUSC with high LRRK2 expression positively corresponds to a high expression of anti-inflammatory cytokines but not inflammatory cytokines. Similarly, the increased expression of interleukin (IL)10-related genes was shown to be significantly linked in LRRK2-high LUSC patients having a poor prognosis. Moreover, the tumor immune estimation resource (TIMER) database suggests that macrophages are one of the cellular sources of IL10 in LRRK2-high LUSC patients. Collectively, our results demonstrate that the postulated LRRK2-IL10 axis is a potential therapeutic target and prognostic biomarker for LUSC.

• Journal of the Korea Society of Computer and Information
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• v.28 no.7
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• pp.113-120
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• 2023

The purpose of this study was the accuracy of cardiac compression, fatigue, and physiological changes of the rescuer for different mask type in cardiopulmonary resuscitation(CPR). Data collection was from 9 to 12 May 2022, the participants were a total of 24 paramedic students with a BLS provider at D University. The students participated in an experiment in which 12 students each wore a surgical mask (Dental mask) and a fine particle 94% blocking mask (KF94 mask) and performed CPR for 2 minutes over a total of 7 times. As a result of the study, in the analysis of the quality of the rescuer's chest compression according to the type of mask, there was a significant difference in the compression speed (F=24.91, p<.001) and bad compression hand position (F=14.54, p=.024) in the group wearing the KF94, Fatigue showed significant differences in both the Dental mask group (F=51.16, p<.001) and the KF94 mask group (F=63.49, p<.001). Among the physiological changes, heart rate showed a significant difference between the Dental mask group (F=34.79, p<.001) and the KF94 mask group (F=35.55, p<.001), and the respiratory rate showed a significant difference between the Dental mask group (F=25.02, p=.001) and the KF94 mask group(F=23.02, p=.002). Therefore, in order to improve the quality of efficient chest compression and reduce the fatigue and physiological changes of rescuers, it will be necessary for rescuers to wear suitable personal protective equipment.

• Industry Promotion Research
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• v.8 no.3
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• pp.153-162
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• 2023

Shen-Xiao-Zhan's 『Zi-Ping-Zhen-Quan』, which is called a commentary on Chart-Structure in MyungLiollgy, After selecting the Chart-Structure and classifying the good luck and bad luck of the case, the Phase-usage is set up according to the principle of Shun reverse. At this time, if two or more the sky symbol hidden in the ground of Monthly intertwine to form several Structure and become Adjunct-Structure, the subject of Structure must be finally known to set up Phase-usage and succeed Structure and failure can be judged. However, in 『Zi-Ping-Zhen-Quan』, only the structure and meaning of Adjunct-Structure were explained, and the method of determining the final subject of Adjunct-Structure was not described. This researcher reviewed various literatures for a study on selecting the subject of Adjunct-Structure, and compared and analyzed various actual cases of Adjunct-Structure by dividing them into Monthly and Chart-Structure. Common results related to the type of sign of the land that met with Monthly, the energy force of the sky sign projected from the sky symbol hidden underground in Monthly and the strength and weakness of the body were drawn. and the law was organized subjectively. It is believed that the results of this study will serve as an opportunity to reduce the confusion of Adjunct-Structure.

• Journal of Service Research and Studies
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• v.11 no.2
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• pp.67-77
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• 2021

This study is a study on the methodology of establishing an innovation strategy centering on the customer experience, which is essential in order to transform the existing collection and preservation-centered mutual aid company service into a visitor-centered service. To this end, we conducted literature research on environmental changes in the funeral industry from the perspective of service science and the significance and value of customer experiences within them, good customer experiences and bad customer experiences from the perspective of customer experience management. A study was conducted to present and prove a specific model. The customer experience-oriented innovation strategy of the funeral industry means to search for various alternatives that can reach the target state from the present state, focusing on the customer, and select the most appropriate transformation plan among them. As an effect of application, it was found that it is a source of differentiation by generating positive emotions to customers, and that customer experience data is highly helpful in making important decisions for the actual resource input of the parent company. This innovation model was presented, and its value was firstly proved by analyzing the difference from the existing evaluation method. Finally, as a result of analyzing the causal relationship through regression analysis using the customer experience measurement procedure, customer experience diagnosis/evaluation, customer experience innovation strategy, and cooperative company's performance as variables, the relationship proved to be significant.

• Journal of Service Research and Studies
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• v.11 no.1
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• pp.21-30
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• 2021

This study examined methodologies for establishing a customer experience-focused innovation strategy, which is essential to transforming existing collection and preservation-oriented museum service into a visitor-oriented service. To this end, a review of studies examining good customer experience and bad customer experience was conducted, focusing on change in museum environments and customer experience from the service science and customer experience management perspectives. Research was conducted to present and prove. Implementing a customer experience-oriented innovation strategy in a museum requires exploring the various approaches that can be used to reach the target state from the present state, focusing on the customer, and selecting the most appropriate transformation plan. This study found that effective approaches are distinguished by the fact that they generate positive emotions in customers and use customer experience data to make important decisions regarding the establishment of practical resources in museums. This innovation model was developed and validated by analyzing how it differed from existing evaluation methods. Finally, a regression analysis using the customer experience measurement procedure, customer experience diagnosis/evaluation, customer experience innovation strategy, and museum performance as variables revealed a significant causal relationship.

• KIPS Transactions on Software and Data Engineering
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• v.12 no.5
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• pp.199-206
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• 2023

The current software becomes the huge size of source codes. Therefore it is increasing the importance and necessity of static analysis for high-quality product. With static analysis of the code, it needs to identify the defect and complexity of the code. Through visualizing these problems, we make it guild for developers and stakeholders to understand these problems in the source codes. Our previous visualization research focused only on the process of storing information of the results of static analysis into the Database tables, querying the calculations for quality indicators (CK Metrics, Coupling, Number of function calls, Bad-smell), and then finally visualizing the extracted information. This approach has some limitations in that it takes a lot of time and space to analyze a code using information extracted from it through static analysis. That is since the tables are not normalized, it may occur to spend space and time when the tables(classes, functions, attributes, Etc.) are joined to extract information inside the code. To solve these problems, we propose a regularized design of the database tables, an extraction mechanism for quality metric indicators inside the code, and then a visualization with the extracted quality indicators on the code. Through this mechanism, we expect that the code visualization process will be optimized and that developers will be able to guide the modules that need refactoring. In the future, we will conduct learning of some parts of this process.

• Journal of Navigation and Port Research
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• v.47 no.3
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• pp.128-133
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• 2023

In order for Aids to Navigation to provide sustainable services to users, it is possible when there is no Aids to Navigation accident. If an Aids to Navigation accident occurs, the manager should efficiently manage it to prevent the same accident. However, the current Aids to Navigation accident management only specifies the cause and type of the accident. There are no separate guidelines. Thus, the accident is recorded differently depending on the manager. Therefore, this study attempted to redefine Aids to Navigation accident. To this end, Aids to Navigation accidents that have occurred over the past 23 years (year 2000 to years 2022), IALA's Aids to Navigation information standard, S-201, and categories of accidents (traffic accidents and marine accidents) were analyzed. Causes of Aids to Navigation accidents were divided into internal and external causes. Accidents were divided into three types: Light tower accident, buoy accident, and equipment accident. By further subdividing primary items, the cause of accident was reestablished into 7 items such as mooring and bad weather and 11 items such as Light tower damage, buoy loss, and equipment breakdown. These research results can be used as basic data to provide future Aids to Navigation accident statistics.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.26 no.3B
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• pp.271-278
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• 2006

In design of groyne series, groyne spacing is a important factor and have an effect on not only the characteristics of backward and recirculation flow in groyne zone but also flow field in main channel. It is necessary study about flow pattern of recirculation zone and main channel that is a cause of bad change, local scour and bank erosion by groyne spacing. In this study, flow variation of groyne zone and main chanel for spacing of groynes were analyzed from the experiment results in order to offer a fundamental data that can be used to decide the proper groyne spacing. Experiments were conducted 12 cases for groyne spacing(L) by groyne length(l) rate and the velocity profile was measured using LSPIV and ADV. From the results, two vortex flows developed in recirculation zone for L/l=3~9 and three vortex flows developed over L/l=10. The velocity of backward flow in recirculation zone was decreased up to 20% over L/l=4. The velocity of main channel flow was increased from 1.3 to 2.0 times by groyne spacing and the rate of velocity increased by increasing groyne spacing. The maximum velocity occurred in 0.7~0.8 times of groyne spacing downstream of upper groyne.

• Journal of the Korean Society of Food Culture
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• v.22 no.6
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• pp.765-774
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• 2007

Aging rate of rural area in our country is relatively high compared to that of the urban area. Thus, the introduction of meal service for the elderly residing in the rural area is necessary for their better living quality. Food habit, health and the nutritive intake conditions during the busy farming season were surveyed and comparative analysis of dietary intake for the introduction of meal service in pavilion of the elderly living in Chungnam, Kangwon, Jeonnam and Kyungbuk was performed for basic reference data of meal service introduction to the pavilion of the elderly in rural area. In general subject, the male elderly had a significant difference in marital state and showed that 79.4% was married and 20% was separated by death(P<0.05). In allowance, there were no significant difference but most of them lived with less then three hundred thousand won and especially, female lived with less then one hundred thousand won. In health state, the female elderly showed significant difference on difficulty with every day activity but with small trouble although they had to prepare their own meal(P<0.05). The condition dental health conditions of the female elderly had a significant difference showing bad conditions in following order; Kangwon(48%)>Chungnam(38.1%)>Kyungbuk(22.9%)>Jeonnam(22.5%)(p<0.05). The female elderly showed a significant difference in usage of denture and number of the female elderly without using the denture were very high(p<0.05). In nutrition intake condition, amount of sodium was very high but intakes of fiber and calcium were relatively 1ow(P<0.05). Meal service introduction in the pavilion of the elderly is suggested for the improvement of the life quality of the elderly in rural area. When developing the menu for them, conditions such as shortage of the fiber and calcium in diets, the dental conditions should be considered.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.30 no.5B
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• pp.479-486
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• 2010

Reliable hydrologic data acquisition is the basic and essential requirement for efficient water management. Especially the acquisition of various stream data in a certain location is very important to construct on alarm system to response an urban flood which occurs frequently due to the effect of climate change. Although the frequency of stream inundation flood occurrence becomes low owing to the consistent stream improvement, the urban flood due to the drainage system problems such as deterioration and bad management occurs continuously. The consistent management and current status understanding of the urban drainage system is essential to reduce the urban flood. The purpose of this study is to develop the urban runoff network flow velocity monitoring system which has the capability of collecting stream data whenever, wherever and to whomever without expert knowledge using Code Division Multiple Access technique and Bluetooth near-distance wireless communication technique. The urban runoff network flow velocity monitoring system consists of three stages. In the first stage, the stream information obtained by using ubiquitous floater is transferred to the server computer. In the second stage, the current state of the urban drainage system is assessed through the server computer. In the last stage, the information is provided to the user through a GUI. As a result of applying, the developed urban runoff network flow velocity monitoring system to Woncheon-Stream in Suwon, the information necessary for urban drainage management can be managed in real time.