• 제목/요약/키워드: BPS

검색결과 373건 처리시간 0.03초

Identification of Gene Expression Signatures in the Chicken Intestinal Intraepithelial Lymphocytes in Response to Herb Additive Supplementations

  • Won, Kyeong-Hye;Song, Ki-Duk;Park, Jong-Eun;Kim, Duk-Kyung;Na, Chong-Sam
    • Asian-Australasian Journal of Animal Sciences
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    • 제29권10호
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    • pp.1515-1521
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    • 2016
  • Anethole and garlic have an immune modulatory effects on avian coccidiosis, and these effects are correlated with gene expression changes in intestinal epithelial lymphocytes (IELs). In this study, we integrated gene expression datasets from two independent experiments and investigated gene expression profile changes by anethole and garlic respectively, and identified gene expression signatures, which are common targets of these herbs as they might be used for the evaluation of the effect of plant herbs on immunity toward avian coccidiosis. We identified 4,382 and 371 genes, which were differentially expressed in IELs of chickens supplemented with garlic and anethole respectively. The gene ontology (GO) term of differentially expressed genes (DEGs) from garlic treatment resulted in the biological processes (BPs) related to proteolysis, e.g., "modification-dependent protein catabolic process", "proteolysis involved in cellular protein catabolic process", "cellular protein catabolic process", "protein catabolic process", and "ubiquitin-dependent protein catabolic process". In GO analysis, one BP term, "Proteolysis", was obtained. Among DEGs, 300 genes were differentially regulated in response to both garlic and anethole, and 234 and 59 genes were either up- or down-regulated in supplementation with both herbs. Pathway analysis resulted in enrichment of the pathways related to digestion such as "Starch and sucrose metabolism" and "Insulin signaling pathway". Taken together, the results obtained in the present study could contribute to the effective development of evaluation system of plant herbs based on molecular signatures related with their immunological functions in chicken IELs.

항산화제가 Bromopropane에 의해 손상된 돼지 과립막세포의 생존율, 원형질막 온전성 및 apoptosis에 미치는 영향 (Effects of antioxidants on viability, plasma membrane integrity and apoptosis in porcine ovarian granulosa cells damaged by bromopropane)

  • 이승형;박희우;이상희;정희태;박춘근;양부근
    • 한국수정란이식학회지
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    • 제31권3호
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    • pp.145-151
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    • 2016
  • The purpose of this study was to examine the effects of taurine and vitamin E on ovarian granulosa cells damaged by bromopropane (BP) in pigs. We evaluated cell viability, plasma membrane integrity (PMI) and apoptotic morphological change in porcine ovarian granulosa cells. The cells were treated with 1-BP (0, 5.0, 10, and $50{\mu}M$), 2-BP (0, 5.0, 10, and 50 mM), taurine (0, 5.0, 10, and 25 mM), and vitamin E (0, 100, 200, and $400{\mu}M$) for 24 h. $10{\mu}M$ 1-BP and $50{\mu}M$ 2-BP inhibited viability and PMI, and induced apoptosis in porcine ovarian granulosa cells (p < 0.05). Cell viability and PMI were increased by taurine (10 and 25 mM) and vitamin E (100 and $200{\mu}M$), and apoptosis decreased (p < 0.05). Finally, the porcine ovarian granulosa cells were co-treated with BPs ($10{\mu}M$), taurine (10 mM) and/or vitamin E ($200{\mu}M$). Cell viability and PMI in the co-treated cells were increased, and apoptosis was decreased. In conclusion, taurine and vitamin E can improve cell viability and inhibition of apoptosis in porcine ovarian granulosa cells damaged by bromopropane.

액정의 Kerr 효과를 이용한 액정표시소자 연구 (Study on Liquid Crystal Displays Utilizing Kerr effect)

  • 김민수;강병균;정준호;하경수;송은경;윤석인;김미영;이명훈;이승희
    • 한국전기전자재료학회:학술대회논문집
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    • 한국전기전자재료학회 2009년도 하계학술대회 논문집
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    • pp.295-296
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    • 2009
  • There are various application of liquid crystal materials to devices, especially, blue phase liquid crystal (BPLC) and nano-structured liquid crystal mixture have been studied recently because BPs existing temperature range has been expanded by polymer-stabilization and liquid crystal has been confined in room which has certain coherence length so that their particular characters, such as fast response time and optically isotropic state at no electric field, could apply to advanced liquid crystal display devices. However, there is an crucial problem which is high operating voltage from low Kerr constant and limited electric field utilization using in-plain electric field. In this paper, we will analyze cell structure in the way of using electric field and show effective electric field utilization to reduce operating voltage.

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Mouse Leukemia 세포에서 Adenosine 5'-triphosphate에 의한 Apoptosis (Apoptosis Induced by Adenosine 5'-triphosphate in Mouse Leukemic Cells)

  • 주난영;박규상;정해숙;공인덕;이중우
    • The Korean Journal of Physiology and Pharmacology
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    • 제1권6호
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    • pp.817-824
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    • 1997
  • Extracellular ATP elicits various biological responses and plays a significant role in physiological regulation. Recently, ATP-induced growth inhibitions were reported in some tumor cell lines, but these effects and mechanisms are not well hewn. This study was conducted to investigate ATP-induced growth inhibition in mouse $leukemic(P388D_1)$ cells. ATP inhibited cell growth in a dose-dependent manner as analyzed by MTS assay$(IC_{50}: 33.1\;{\mu}M)$. Nucleotides other than ATP, such as ADP$(37.5;{\mu}M)$ and AMP$(33.2;{\mu}M)$ had the same effects as ATP but adenosine$(57.8;{\mu}M)$ showed less effect than ATP. ATP attenuated the cells in $G_0/G_l\;and\;G_2/M$ phases but increased those in S phase in flow cytometric analysis. Hypodiploid cells$(A_0)$, the presumptive findings of apoptosis, were found among the ATP-treated cells. ATP induced DNA fragmentation into $180{\mu}200\;bps $as measured by electrophoresis. some apoptotic cells were stained by TUNEL method. ATP increased the intracellular free $Ca^{++}$concentration$([Ca^{++}]_i)$ and the increment of $([Ca^{++}]_i)$ was caused by influx from the extracellular space. These results suggest that extracellular ATP induces growth inhibition through apoptosis.

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무선 다점 온도센서에 의한 빌딩의 화재 탐지 (Fire Detection of a Building Using Wireless Multi-point Temperature Sensors)

  • 김치엽;권일범
    • 비파괴검사학회지
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    • 제24권5호
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    • pp.494-498
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    • 2004
  • 현대의 대형 건물은 복잡한 전기 배선 또는 가스 배관 등의 설비를 갖추고 있어서 다양한 화재 사고가 발생할 가능성이 커졌다. 이에 따라 무선의 다점 온도 측정 센서를 손쉽게 여러 위치에 설치 가능하도록 저렴하게 개발하여 적용함에 의하여 화재를 조기에 탐지하고 그 피해의 크기를 최소화하는 것이 필요하다. 무선 온도 센서의 송신기는 4채널로 9600 bps의 전송속도와, 10 mW의 출력으로 915 MHz 통신 주파수를 갖고 수신기와 작동되도록 구성하였다. 온도범위 $-55{\sim}150$도 사이에서 사용할 수 있도록 검증된 반도체 온도 센서 소자를 기본으로 사용하여 4개의 채널을 구성하고 실험을 수행한 결과 개발된 센서 시스템이 화재 탐지용으로 적용이 가능함을 확인하였다.

이중구조 가연성 독봉의 핵설계 특성 평가 (An Evaluation of Nuclear Design Characteristics of Duplex Burnable Absorber Rods)

  • 이대진;김명현;송근우;정연호
    • 한국에너지공학회:학술대회논문집
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    • 한국에너지공학회 2002년도 추계 학술발표회 논문집
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    • pp.71-79
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    • 2002
  • 이중구조 가연성독봉(Duplex BP)의 성능을 평가하기 위해 한국표준형발전소 24개월 주기를 기준으로 16개 Gadolinia 독봉이 장전된 핵연료집합체에 대해 핵적 평가를 수행하였다. 16개 Gd 독봉이 장전된 핵연료집합체와 동일한 반응도 억제가를 갖는 Duplex 독봉집합체를 설계하기 위해 내심에 Natural U-12wt%Gd$_2$O$_3$, 외심에는 4.95wt%$UO_2$-2w/oEr$_2$O$_3$을 넣어 이중 성형한 24개의 이중구조 가연성독봉이 장전된 핵연료집합체를 설계하였다. 또한 같은 방법으로 140개의 Erbia 독봉이 장전된 등가핵연료집합체를 설계하였다. 핵설계 특성평가를 위해 연소도에 따른 무한증배계수, 반응도억제가, 첨두봉출력 그리고 냉각재 온도재수에 대한 변화에 대해서 비교하였다. Duplex 독봉은 Gadolinia 독봉에 비해 k-inf의 2차 첨두현상을 완화시켜 반응도 제어면에서 유리한 것으로 나타났다. 그러나, 다량의 Erbia 독봉을 전체적으로 골고루 장전한 핵연료집합체보다는 Duplex BP를 장전한 핵연료집합체가 노심내 반응도 제어면에서 유리하지 못한 것으로 나타났다.

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QoS-Aware Approach for Maximizing Rerouting Traffic in IP Networks

  • Cui, Wenyan;Meng, Xiangru;Yang, Huanhuan;Kang, Qiaoyan;Zhao, Zhiyuan
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • 제10권9호
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    • pp.4287-4306
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    • 2016
  • Network resilience provides an effective way to overcome the problem of network failure and is crucial to Internet protocol (IP) network management. As one of the main challenges in network resilience, recovering from link failure is important to maintain the constancy of packets being transmitted. However, existing failure recovery approaches do not handle the traffic engineering problem (e.g., tuning the routing-protocol parameters to optimize the rerouting traffic flow), which may cause serious congestions. Moreover, as the lack of QoS (quality of service) restrictions may lead to invalid rerouting traffic, the QoS requirements (e.g., bandwidth and delay) should also be taken into account when recovering the failed links. In this paper, we first develop a probabilistically correlated failure model that can accurately reflect the correlation between link failures, with which we can choose reliable backup paths (BPs). Then we construct a mathematical model for the failure recovery problem, which takes maximum rerouting traffic as the optimizing objective and the QoS requirements as the constraints. Moreover, we propose a heuristic algorithm for link failure recovery, which adopts the improved k shortest path algorithm to splice the single BP and supplies more protection resources for the links with higher priority. We also prove the correctness of the proposed algorithm. Moreover, the time and space complexity are also analyzed. Simulation results under NS2 show that the proposed algorithm improves the link failure recovery rate and increases the QoS satisfaction rate significantly.

혼재망에서 IPTV 서비스를 위한 계층부호화 방식 결정 방법에 대한 연구 (A study on decision on scalable coding method for IPTV service over heterogeneous network)

  • 김대연;서덕영;김영수;김진상
    • 방송공학회논문지
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    • 제12권2호
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    • pp.93-101
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    • 2007
  • 혼재 네트워크 (heterogeneous networks) 환경에서는 IPTV 서비스를 위해 계층부호화 방식 (SVC, Scalable Video Coding)이 사용될 것이다. 본 논문은 공간적 (spatial), 품질적 (quality), 시간적 (temporal) 세 가지의 계층화 방식을 (scalable coding) 혼합한 혼합 계층화 방식 (hybrid scalable coding)에서 최종 디스플레이 되는 레벨에 따라 계층간 참조 (inter-layer reference)하는 계층을 결정하는 방식에 대하여 분석하였다. 공간적 계층화에서 위신호(僞信號) (aliasing) 방지를 위해 제거되는 고주파 성분과 품질적 계층화에서 양자화에 의해서 생기는 잡음간의 관계에 따라 공간적 하부 계층에서 요구되는 품질은 어느 정도가 적합한지를 결정한다. 본 논문은 공간적 계층화와 품질적 계층화의 레벨 선택은 비디오 시퀀스의 특성에 따라 결정되어야함을 보인다.

무선환경 하에서 적응형 변조기를 적용한 다중 반송파 CDMA 시스템의 성능 분석 (Performance Analysis of Multicarrier CDMA System with Adaptive Modulation in Wireless Environment)

  • 이광희;김항래;한태영;김남
    • 한국콘텐츠학회:학술대회논문집
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    • 한국콘텐츠학회 2003년도 추계종합학술대회 논문집
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    • pp.289-302
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    • 2003
  • 본 논문은 무선 환경하에서, 적응형 변조기와 적응형부채널 할당 방식을 적용한 다중 반송파 CDMA 시스템의 성능을 분석한다. 제안한 시스템의 경우, 총 부채널수가 4이고 이 가운데 두 개의 부채널로 데이터를 전송한다면 각 채널의 임계값은 5.2 ㏈, 9 ㏈, 13.2 ㏈와 8.4 ㏈, 12.2 ㏈, 16.3 ㏈ 나타났다. BER이 10-3을 만족하는 평균 E$_{b}$ /N$_{0}$는 8.1 ㏈로 기존의 시스템에 비해 12.9 ㏈의 성능이 개선되었다. 평균 심볼당 비트수는 7 bit의 경우 약 15 ㏈의 평균 E$_{b}$ /N$_{o}$ 가 필요하다.다.

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Development of CINEMA Mission Uplink Communication System

  • Yoon, Na-Young;Yoon, Se-Young;Kim, Yong-Ho;Yoon, Ji-Won;Jin, Ho;Seon, Jong-Ho;Chae, Kyu-Sung;Lee, Dong-Hun;Lin, Robert P.
    • Journal of Astronomy and Space Sciences
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    • 제29권1호
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    • pp.33-40
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    • 2012
  • Triplet Ionospheric Observatory (TRIO) CubeSatforIon, Neutral, Electron MAgneticfields (CINEMA) is a CubeSat with the weight 3 kg that will be operated in the orbit conditions of about 800 km altitude and $90^{\circ}$ inclination angle, using the S-band and ultra-high frequency (UHF)-band communication frequencies. Regarding the communication antenna loaded on the satellite, the two patch antennas has the downlink function in the S-band, whereas the two whip antennas has the function to receive the command sent by the ground station to the satellite in the UHF-band. The uplink ground station that communicates through the UHF-band with the CINEMA satellite was established at Kyung Hee University. The system is mainly composed of a terminal node controller, a transceiver, and a helical antenna. The gain of the helical antenna established at the Kyung Hee University ground station was 9.8 dBi. The output of the transceiver was set to be 5 W (6.9 dB) for the communication test. Through the far-field test of the established system, it was verified that the Roman characters, figures and symbols were converted into packets and transmitted to the satellite receiver in the communication speed of 9,600 bps.