The Korean Journal of Physiology and Pharmacology
- Volume 1 Issue 6
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- Pages.817-824
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- 1997
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- 1226-4512(pISSN)
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- 2093-3827(eISSN)
Apoptosis Induced by Adenosine 5'-triphosphate in Mouse Leukemic Cells
Mouse Leukemia 세포에서 Adenosine 5'-triphosphate에 의한 Apoptosis
- Joo, Nan-Young (Department of Physiology, Yonsei University Wonju College of Medicine) ;
- Park, Kyu-Sang (Department of Physiology, Yonsei University Wonju College of Medicine) ;
- Chung, Hae-Sook (Department of Physiology, Yonsei University Wonju College of Medicine) ;
- Kong, In-Deok (Department of Physiology, Yonsei University Wonju College of Medicine) ;
- Lee, Joong-Woo (Department of Physiology, Yonsei University Wonju College of Medicine)
- 주난영 (연세대학교 원주의과대학 생리학교실) ;
- 박규상 (연세대학교 원주의과대학 생리학교실) ;
- 정해숙 (연세대학교 원주의과대학 생리학교실) ;
- 공인덕 (연세대학교 원주의과대학 생리학교실) ;
- 이중우 (연세대학교 원주의과대학 생리학교실)
- Published : 1997.12.21
Abstract
Extracellular ATP elicits various biological responses and plays a significant role in physiological regulation. Recently, ATP-induced growth inhibitions were reported in some tumor cell lines, but these effects and mechanisms are not well hewn. This study was conducted to investigate ATP-induced growth inhibition in mouse
Keywords
- Adenosine 5'-triphosphate(ATP);
- Leukemic cells;
- Apoptosis;
- Intracellular free calcium concentration$([Ca^{++}]i)$