• Journal of Communications and Networks
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• v.3 no.4
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• pp.361-364
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• 2001

Over an additive abelian group G of order g and for a given positive integer $\lambda$, a generalized Hadamard matrix GH(g, $\lambda$) is defined as a gλ$\times$gλ matrix[h(i, j)], where 1 $\leq i \leqg\lambda and 1 \leqj \leqg\lambda$, such that every element of G appears exactly $\lambd$atimes in the list h($i_1, 1) -h(i_2, 1), h(i_1, 2)-h(i_2, 2), …, h(i_1, g\lambda) -h(i_2, g\lambda), for any i_1\neqi_2$. In this paper, we propose a new method of expanding a GH(g^m, \lambda_1) = B = [B_{ij}] over G^m$ by replacing each of its m-tuple B_{ij} with B_{ij} + GH(g, $\lambda_2) where m = g\lambda_2. We may use g^m/\lambda_1 (not necessarily all distinct) GH(g, \lambda_2$)s for the substitution and the resulting matrix is defined over the group of order g.

• Aerospace Engineering and Technology
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• v.13 no.1
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• pp.1-9
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• 2014

Goheung aeronautical center is located in the area of Goheung of which land is reclaimed from sea and has a runway of length 700m, width 25m with test facility which has been used for flight test of UAV and small aircraft. To support the enhancement of aircraft safety, 1090ES ADS-B ground system as the ground surveillance system has been implemented. ADS-B system based on GPS and digital data link provides the function of enhancing the aircraft safety through flight information among aircrafts. This paper gives the result that the implementation of ADS-B ground system and the flight test with onboard ADS-B transmitter has been conducted.

• Journal of Korean Society for Atmospheric Environment
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• v.10 no.1
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• pp.32-40
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• 1994

Continuous measurements of the extinction coefficient( $b_{ext}$ ) and scattering coefficient due to Particle( $b_{sp}$ ) were made during the fall 1993 in Seoul along with the measurements of the size distribution, ionic composition of particles. On the average, $b_{sp}$ values are 55% and 79% of $b_{ext}$ values during the clear and smoggy Periods respectively. Also the average values of $b_{ext}$ and $b_{sp}$ were 0.791$\times$10$^{-3}$ $m^{-1}$ (visual range 4.9km) and 0.628$\times$10$^{-3}$ $m^{-1}$ (visual range 6.2km) during the smoggy Period, and 0.297$\times$10$^{-3}$ $m^{-1}$ (visual range 13.1km) and 0.164$\times$10$^{-3}$ $m^{-1}$ (visual range 23.8km) during the clear period, respectively. The Peak at about 1${\mu}{\textrm}{m}$ of the Particle size distribution during the smoggy period is about four times higher than that during the clear period while the peaks at about 5${\mu}{\textrm}{m}$ during both periods are similar. Also, the concentrations of sulfate and nitrate at about 1${\mu}{\textrm}{m}$ during the smoggy Period are much higher than these during the clear Period.eriod.

• Explosives and Blasting
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• v.11 no.2
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• pp.60-68
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• 1993

The noise and vibration generated by the subway rolling stocks operated along the Seoul Subway Line No.1, 2, 3, and 4 lead to a controversy of pollution problem especially in residential areas. However, there is no data or guide to define the damage or provide adequate protection against such pollutions. The field measurements were made to characterize the noise attenuation due to distance, noise level distribution around the subway track of the aboveground and underground parts of each Line. The assessment criteria and methods are considered in addition to the practical available noise control methods. The noise level measured at Line No. 1 and 3 are less than 60 dB(A) with no pollution problem. Only a part of the aboveground section of Line No.2 and 4 indicates severe noise pollution. The effective boundary of these areas exposed to 70dB (A) noise are within 50m from the track centerline of No.2 line and 25m of No.4 line. The residents file a strong complaints whenever the noise level exceeds the 80dB (A) , and an occasional complaints between 70 to 80 dB(A). The distribution of high level noise of 80 dB(A) occurs within 25m from the track centerline of the overbridge, 12.5m of the short steel bridge, and about loom of the long steel bridge such as Dangsan Bridge. The intermediate noise level of 70 to 80 dB(A) is recorded within 50m from the overbridge, U-type retaining structure, and short steel structure, and 280m from the long steel bridge. The results presented in this paper can be used to understand the characteristics of the noise pollution along the Seoul Subway now In operation, and used as a guide to improve the existing noise pollution problems.

• Journal of the Institute of Electronics Engineers of Korea SD
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• v.48 no.7
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• pp.23-29
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• 2011

A dB-linearity improved variable gain amplifier (VGA) for GPS receiver is presented. The Proposed dB-linear current generator has improved dB-linearity error of ${\pm}0.15$dB. The VGA for GPS is designed using proposed dB-linear current generator and composed of 3 stage amplifiers. The IF frequency is assumed as 4MHz and the linearity requirement of the VGA for GPS receiver is defined as 24dBm of IIP3 using cascaded IIP3 equation and the VGA satisfies 24dBm when minimum gain mode. The DC-offset voltage is eliminated using DC-offset cancelation loop. The gain range is from -8dB to 52dB and the dB-linearity error satisfies ${\pm}0.2$dB. The 3-dB frequency has range of 35MHz~106MHz for the gain range. The VGA is designed using 0.18${\mu}m$ CMOS process. The power consumption is 3mW with 1.8V supply voltage.

• Tuberculosis and Respiratory Diseases
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• v.51 no.4
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• pp.315-324
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• 2001

Background : IL-8 is a potent chemotactic cytokine that plays an important role in the host defense mechanism against M. tuberculosis by recruiting inflammatory cells to the site of the infection. Lung epithelial cells, as well as alveolar macrophages are known to produce IL-8 in response to M. tuberculosis. IL-8 gene expression is mainly regulated on the level of transcription by NF-${\kappa}B$. This study investigated whether or not A549 cells produce IL-8 in NF-${\kappa}B$ dependent mechanism in response to macrophages phagocytosing M. tuberculosis. Methods : Peripheral blood monocytes that were obtained from healthy donors were cultured for 24 h with M. tuberculosis and a conditioned medium(CoMTB) was obtained. As a negative control, the conditioned medium without M. tuberculosis (CoMCont) was used. A549 cells were stimulated with M. tuberculosis, CoMCont and CoMTB and the IL-8 concentration in the culture media was measured by ELISA. The CoMTB induced IL-8 mRNA expression in the A549 cells was evaluated using RT-PCR, and CoMTB induced $I{\kappa}B{\alpha}$ degradation was measured using western blot analysis. CoMTB induced nuclear translocation and DNA binding of NF-${\kappa}B$ was also examined using an electrophoretic mobility shift assay(EMSA), and the CoMTB induced NF-${\kappa}B$ dependent IL-8 transcriptional activity was measured using a luciferase reporter gene assay. Results : CoMTB induced IL-8 production by A549 cells($46.8{\pm}4.8\;ng/ml$) was higher than with direct stimulation with M. tuberculosis ($6.8{\pm}2.9\;ng/ml$). CoMTB induced IL-8 mRNA expression increased after 2 h of stimulation and was sustained for 24 h. $I{\kappa}B{\alpha}$ was degraded after 10 min of CoMTB stimulation and reappeared by 60 min. CoMTB stimulated the nuclear translocation and DNA binding of NF-${\kappa}B$. The CoMTB induced NF-${\kappa}B$ dependent IL-8 transcriptional activity($13.6{\pm}4.3$ times control) was higher than either CoMCont($2.0{\pm}0.6$ times control) or M. tuberculosis ($1.4{\pm}0.6$ times control). Conclusion : A conditioned medium of peripheral blood monocytes phagocytosing M. tuberculosis stimulates NF-${\kappa}B$ dependent IL-8 production by the lung epithelial cells.

• Journal of the Korean Society of Food Science and Nutrition
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• v.46 no.10
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• pp.1186-1194
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• 2017

Recently, many people have demanded reliable nutritional data even for minor-components. On the other hand, an analytical method for the analyses of vitamin $B_5$ and $B_6$ is lacking. Therefore, this study attempted to validate with accuracy and precision the analysis of vitamin $B_5$ and $B_6$ using a high-performance liquid chromatography (HPLC) method. The vitamin $B_5$ and $B_6$ contents were analyzed using an Agilent 1260 series HPLC system. YMC-Pack ODS-AM ($250{\times}4.6mm$ I.D.) and YMC-Pack Pro RS $C_{18}$ ($250{\times}4.6mm$ I.D.) columns were used for the analyses of vitamin $B_5$ and $B_6$, respectively. In the case of vitamin $B_5$, the flow rate was set to 1.0 mL/min by isocratic elution using the 50 mM $KH_2PO_4$ solution (pH 3.5)/acetonitrile (ACN) (95:5, v/v) with monitoring at 200 nm using HPLC/DAD, whereas the flow rate for vitamin $B_6$ was set to 1.0 mL/min of flow rate by isocratic elution using a 20 mM $CH_3CO_2Na$ solution (pH 3.6)/ACN (97:3, v/v) with monitoring by excitation at 290 nm and emission at 396 nm using HPLC/FLD. The column temperature was set to $30^{\circ}C$. The injection volume was $20{\mu}L$ for each experiment. The specificity of the accuracy and precision for vitamin $B_5$ and $B_6$ were also validated by HPLC. The results showed high linearity in the calibration curve for vitamin $B_5$ ($R^2=0.9998^{{\ast}{\ast}}$), the limit of detection (LOD) and limit of quantitation (LOQ) were 0.4 mg/L and 1.3 mg/L, respectively, In contrast, for the calibration curve of vitamin $B_6$, which showed high linearity ($R^2=0.9999^{{\ast}{\ast}}$), the LOD and LOQ were 0.006 mg/L and 0.02 mg/L, respectively.

• Tuberculosis and Respiratory Diseases
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• v.57 no.1
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• pp.25-31
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• 2004

Background : IFN-${\gamma}$ is the main effector mediator of the host immune response against Mycobacterium tuberculosis. Evaluating the IFN-${\gamma}$ gene expression in response to M. tuberculosis antigens may help in elucidating the host defense mechanism against M. tuberculosis and in the development of a vaccine. Methods : The IFN-${\gamma}$ mRNA expression in the lymphocytes obtained from pleural effusions from tuberculous pleurisy patients (TB-PLC) after in vitro stimulation with whole cell M. tuberculosis(H37Rv), purified protein derivatives(PPD), man-lipoarabinamman (man-LAM), ara-LAM and Antigen 85B(Ag85B) were evaluated. The degree of IFN-${\gamma}$ mRNA expression was determined by a semiquantitative reverse transcriptase-polymerase chain reaction (RT-PCR) method. Results : M. tuberculosis induced the expression of IFN-${\gamma}$ mRNA in the TB-PLC in time and dose dependent manners. The PPD and Ag85B induced high levels of IFN-${\gamma}$ mRNA expression in the TB-PLC. However, man-LAM inhibited IFN-${\gamma}$ mRNA expression in the TB-PLC, while ara-LAM did not. Conclusion : IFN-${\gamma}$ mRNA expression in TB-PLC is stimulated by PPD and Ag85B, but inhibited by man-LAM.

• Natural Product Sciences
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• v.16 no.4
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• pp.239-244
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• 2010

Protein tyrosine phosphatase 1B (PTP1B), a negative regulator of insulin signaling, has served as a potential drug target for the treatment of type 2 diabetes. The MeOH extracts of twenty-nine medicinal plants, traditionally used in Vietnam as anti-diabetes agents, were investigated for PTP1B inhibitory activity in vitro. The results indicated that, most materials showed moderate to strong inhibitory activity with $IC_{50}$ values ranging from $3.4\;{\mu}g/mL$ to $35.1\;{\mu}g/mL$; meanwhile, eleven extracts (37.9%) could demonstrate PTP1B activity with $IC_{50}$ values less than $15.5\;{\mu}g/mL$; sixteen extracts (55.2%) could demonstrate PTP1B activity with $IC_{50}$ values ranging from $15.5\;{\mu}g/mL$ to $35.1\;{\mu}g/mL$. The study may provide a proof, at least in a part, for the ethno-medical use in diabetes disease of these plants.

• Proceedings of the Korean Vacuum Society Conference
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• 2013.08a
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• pp.270.2-270.2
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• 2013

직선운동하는 하전입자의 진행방향에 수직한 평면상에 서로 직교하는 전기장과 자기장을 걸어주면, 하전입자에는 전기장에 의한 힘 FE와 자기장과 속도 v에 의한 로렌츠력 $F_B=q(v{\times}B)$가 동시에 작용하게 된다. 이때 Wien 조건 FB=-FE를 만족하는 질량 mA과, 에너지 EA를 가지는 하전입자 A는 휘지 않고 직선운동을 계속하나, 하전입자 A와 다른 에너지 $E_B\;(=E_A+{\delta}E)$나 질량 $m_B\;(=m_A+{\delta}m)$을 가지는 하전입자는 휘게 되며, 그 휘는 정도는 ${\delta}E$나 ${\delta}m$에 비례하게 된다. 이 현상을 이용하여 다양한 종류의 에너지 또는 질량 분석기가 독일, 미국, 일본 등의 분석기기 선진국에서 개발되어 왔고, 전자현미경의 이미지 필터로도 활용되고 있으며, 통상 EXB 필터 또는 발명자의 이름을 딴 Wien 필터로 불리어지고 있다. $E{\times}B$ 필터는 일반적인 하전입자빔 렌즈와 다른 광학특성을 가지며, 지난 발표에서는 $E{\times}B$ 필터의 기본 궤도 방정식 및 다양한 2차 기하 수차 방정식의 유도과정 및 결과를 보여주었다. 본 발표에서는 EXB 필터의 전후에 배치시켜, 초점거리 등의 조정을 수행할 4극자와, $E{\times}B$ 필터에서 발생하는 2차 수차의 보정을 수행할 6극자의 광학특성의 계산 결과를 보여준다. 4극자-6극자-EXB필터-6극자-4극자 조합의 기본 광학궤도 계산 결과는 빔 다이어그램으로 보여준다. 6극자에 의해 수차를 줄여서 향상되는 에너지 분해능 값은 수치적으로 추정한다. 실제 제작이 된 각 부품의 외형 및 사진을 보여주어 에너지 필터의 제작 진행 상황을 보고한다.