• Transactions of the Korean Society of Mechanical Engineers B
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• v.29 no.3 s.234
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• pp.376-383
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• 2005

In the paper we investigate characteristics of a transitional behavior from a premixed flame to a triple flame in a lifted flame according to the change of equivalence ratio. In previous study, we showed that the stabilized laminar lifted flame regime is categorized by regimes of premixed flame, triple flame and critical flame. A gas-chromatograph is used to measure concentration field, a smoke-wire system is used to measure streak line, and a PIV system is used to measure velocity field in lifted flame. In the visualization experiment of smoke wire, the flow divergence and redirection reappeared in premixed flame as well as triple flame. Thus we cannot express the flame front of lifted flame has a behavior of triple flame with only flow divergence and redirection. In PIV measurement, flow velocity for those three flames has minimum value at the tip of flame front. To differentiate triple flame and premixed flame, $\Phi$ value of partially premixed fraction is employed. The partially premixed fraction $\Phi$ was constant in premixed flame. In critical flame small gradient appears over the whole regime. In triple flame, typical diffusion flame shape is obtained as parabolic distribution type due to diffusion flame trailing.

• Journal of the Korean Crystal Growth and Crystal Technology
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• v.25 no.1
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• pp.6-12
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• 2015

Under rate-controlled sintering, furnace power is controlled to maintain a specific specimen contraction rate. This thermal processing method guarantees continuous process with a minimum thermal energy applied over time and makes it possible to control the density of the sintered body precisely. In this study, the rate-controlled sintering is applied to the sintering of $B_4C$ in order to investigate how rate-controlled sintering variables can affect the sintering behavior and/or grain growth behavior of $B_4C$ and how the results can be interpreted using sintering theories to draw an optimal sintering condition of the rate-controlled sintering. Further, the applicability of the rate-controlled sintering into the study for sintering of unknown materials is also considered.

• Journal of Haehwa Medicine
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• v.9 no.2
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• pp.159-171
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• 2001

In the result of investigating the drugs for replenishing Qi in many herbal books, we could get consistent relation in their immunopharmacologic effects as follows: 1. The effects of drugs for replenishing Qi was shown in the Shen Nong's Herbal, but its classification was natural such as trees and plants, insects and beasts, fruits, vegetables, and we think that trial about classification of drugs for replenishing Qi was accomplished in the ben-cao-jiu-zhen(本草求眞). 2. Main drugs for replenishing Qi was Gingseng Radix, Codonopsis pilosulae Radix, Astragali Radix, Atractylodis macrocephalae Rhizoma, Dioscoreae Rhizoma, Glycyrrhizae Radix. 3. Drugs for replenishing Qi commonly contain polysaccharides as much, and it was thought that they have also immunopharmacolologic effects by means of activating T and B cells, secreting cytokines, making lymphocytes, activating NK cells, increasing abilities of voracity and generating antibodies. 4. Drugs for replenishing Qi mainly replenish lung-Qi and Wei-Qi so that they have also effects of activating T and B cells, secreting cytokines, making lymphocytes, activating NK cells, increasing abilities of voracity and generating antibodies. 5. Drugs for replenishing Qi modulate content of cAMP and inhibit Na(+)-K(+) ATPase, so that they have effects of treating indistinctive pulse from Qi deficiency by means of inhibition delivery of chemical substances, activating lymphocytes. promoting contraction of myocardium.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.25 no.3
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• pp.315-321
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• 2001

Aerodynamic lenses are widely used in generating particle beams of high density and small diameter, but analytical or modeling studies are limited only in the free molecular regime. In this study, it is shown that generating particle beam is also possible in atmospheric pressure range, and the mechanism of generating particle beam using an orifice is analysed into three different parts : fluid dynamic contraction, diffusional defocusing, and inertial focusing. In laminar flow conditions, the diffusional defocusing effect can be neglected, and the effects of inertial focusing can be expressed in terms of the orifice size and Stokes number. Numerical experiments are done for two different orifices, d/D=1/5 and 1/10 and particle diameter d(sub)p=1-10 ㎛. The results for two different orifices can be made into a single curve when a modified Stokes number is used. The inertial focusing effect diminishes when the modified Stokes number becomes smaller than 10(sup)-2.

• Archives of Pharmacal Research
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• v.19 no.6
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• pp.462-468
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• 1996

The present study was undertaken to investigate the effects of age on angiotensin II (AII) response and antagonistic activity of losartan using aortic rings and liver homogenates from rats ranging in age from 0.7 to 20 months. Whether the endothelium was present or not, the maximum contractile response to AII decreased with age. Removal of the endothelium enhanced AII-induced maximum contraction and these endothelial effects seemed to be due to endothelium-derived relaxing factor (EDRF) in all ages. Equilibrium binding studies demonstrated an age-related decrease in maximum binding $(B_{max})$ with little change in binding affinity $(K_d)$. In rat aorta, the extent of losartan-induced parallel shifts $(K_B)$ in AII concentration-response curves was not significantly different between ages. In addition, $IC_{50}$ value of losartan in competition binding was not changed with age in rat liver homogenates. These results suggest that the potency of losartan is not altered with age in rat aorta and liver, although AII-induced contractile response and the maximum AII binding decreased significantly with age.

• Journal of the Korean Society of Physical Medicine
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• v.16 no.3
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• pp.107-113
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• 2021

PURPOSE: Selective strengthening of the transverse abdominis muscle (TrA) during abdominal hollowing makes an important contribution to the stability and control of the spine. This study examined the effects of abdominal hollowing exercise (AHE) according to the visual feedback method on the external oblique, internal oblique, and transverse abdominis muscles. METHODS: Twenty healthy subjects were assigned randomly to an AHE with visual feedback from real-time ultrasound image (group A, n = 10), AHE with visual feedback with pressure biofeedback unit (group B, n = 10). Both groups underwent 20 min of AHE with visual feedback once daily, five days/week for two weeks. The changes in the muscle thickness of the TrA, internal oblique abdominal muscle (IO), and external oblique abdominal muscle (EO) were measured by ultrasonography. RESULTS: The thickness of TrA was changed significantly in both groups (p < .05). However, the lowest minimal detectable changes were achieved in Group A. The thickness of the IO and EO muscles in group A was changed significantly, but there were no significant changes in group B. CONCLUSION: Both visual feedback methods were effective for strengthening the TrA muscles selectively. Nevertheless, AHE with visual feedback using real-time ultrasound images may be more useful in trA muscle contraction.

• The Korean Journal of Pharmacology
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• v.30 no.2
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• pp.191-203
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• 1994

$K^+$ channel openers (KCOs) are known to have a wide range of effects by opening the $K^+$ channel in plasma membranes of various smooth muscles, cardiac muscle and pancreatic ${\beta}-cell$. In the present study, we investigated the effects of 5 types of KCOs, cromakalim, RP49356, pinacidil, nicorandil and diazoxide on the contractility of isolated rat uterus. All KCOs tested inhibited the uterine contraction induced by 0.2 nM oxytocin in a dose-dependent manner. Individual KCO and its $pD_2$ values were cromakalim 6.5, RP49356 6.3, pinacidil 5.92, nicorandil 4.43 and diazoxide 4.18. The relaxant effects of KCO were inhibited by glibenclamide (0.3, 1 and $10\;{\mu}M$) with $pA_2$ values of cromakalim 6.91, RP49356 6.59, pinacidil 6.55, nicorandil 5.97 and diazoxide 6.37. In addition, the relaxant effect of cromakalim or pinacidil was antagonised by TEA, a non-selective $K^+$ channel blocker, but not by apamin. Contractions induced by low concentration of KCI (< 40 mM) were inhibited by cromakalim $(100{\mu}M)$ and nicorandil $(300{\mu}M)$, but those evoked by higher concentration (> 40 mM) of KCI were little affected. In ovariectomized rat uterus, cromakalim dose-dependently inhibited oxytocin-induced contraction and glibenclamide $(10{\mu}M)$ inhibited the relaxant effect of cromakalim with $pD_2$ and $K_B$ values of 7.48 and $1.26{\times}10^{-7}M$, respectively. In estrogen-primed rat uterus, these values were 6.51 and $1.57{\times}10^{-7}M$, respectively, indicating that the cromakalim is less effective on the estrogen-treated uterine smooth muscle. Our results suggest that the KCO-sensitive $K^+$ channels participate in the motility of uterine smooth muscle and such channels are, at least in part, under the control of estrogen. In addition, our data Indicate that the type of $K^+$ channels activated by KCO is ATP-sensitive $K^+$ channels which is blocked by glibenclamide.

• Journal of Korean Physical Therapy Science
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• v.13 no.2
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• pp.99-119
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• 2006

Endothelin (ET) is a 21 amino acid peptide with multifunctional effects on the vasculature as well as a variety of other cell types such as respiratory, gastrointestinal, urogenital, endocrine, central nervous systems, and others. Endothelin has emerged as a modulator by autocrine and paracrine actions for many cellular activities, including vasoconstriction, cell proliferation, hormone production, neurotransmitter and/or neuromodulator. The endothelin family consists of three closely related peptides, ET-1, ET-2, and ET-3 derived from separate genes, such as chromosome 6, 1, and 20, respectively. ET-1 is the predominant isoform produced in the cardiovascular system and about which most is known. Endothelin receptors are seven-transmembrane GTP-binding protein-coupled receptors, which are classified into endothelin-A (ETA) and endothelin-B (ETB) receptors. Interestingly, recent evidence is accumulating to suggest that ET -1 may contribute to a variety of pain states such as allodynia and hyperalgesia in animals and humans. Therefore, in this review the biological characteristics and contraction-related mechanism of endothelin-1 in mammalian cells will be summarized. Especially, we focus on multifunctional roles for ET-1 in noxious stimulation-induced pain for the study of pain specialized physical therapy.

• Journal of The Korean Astronomical Society
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• v.14 no.1
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• pp.37-42
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• 1981

In order to know how the magnetic field increases with density in interstellar clouds, we have analyzed observations of extinction and polarization for stars in the ${\rho}$ Oph molecular cloud complex. The size of grains in dense parts of the complex is estimated to be larger than the ones in diffuse interstellar clouds by about 15 percent in radii. Employing the Davis-Greenstein mechanism for grain alignment with this estimated grain size, we have put constraints on the exponent in the field-density relation $B{\propto}n^x:1/5{\leq}x{\leq}1/3$. It is concluded that magnetic field in gravitationally contracting clouds increases less steeply than the classical expectation based on the approximation of isotropic contraction with complete frozen-in flux.

• Honam Mathematical Journal
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• v.6 no.1
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• pp.1-12
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• 1984

Let(X, $\Im$) be a probabilistic metric space with a t-norm. Common fixed point theorems and convergence theorems generalizing the results of Ćirić, Fisher, Sehgal, Istrătescu-Săcuiu and others are proved for three mappings P,S,T on X satisfying $F_{Pu, Pv}(qx){\geq}min\left{F_{Su,Tv}(x),F_{Pu,Su}(x),F_{Pv,Tv}(x),F_{Pu,Tv}(2x),F_{Pv,Su}(2x)\right}$ for every $u, v {\in}X$, all x>0 and some $q{\in}(0, 1)$. One of the main results is extended to uniform spaces. Mathematics Subject Classification (1980): 54H25.