• BMB Reports
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• 제50권9호
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• pp.437-444
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• 2017

Different types of eukaryotic cells may adopt seemingly distinct modes of directional cell migration. However, several core aspects are regarded common whether the movement is either ameoboidal or mesenchymal. The region of cells facing the attractive signal is often termed leading edge where lamellipodial structures dominates and the other end of the cell called rear end is often mediating cytoskeletal F-actin contraction involving Myosin-II. Dynamic remodeling of cell-to-matrix adhesion involving integrin is also evident in many types of migrating cells. All these three aspects of cell migration are significantly affected by signaling networks of TorC2, TorC1, and PP2A/B56. Here we review the current views of the mechanistic understanding of these regulatory signaling networks and how these networks affect eukaryotic cell migration.

• 한국수학교육학회지시리즈B:순수및응용수학
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• 제16권1호
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• pp.85-98
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• 2009

Strong convergence theorems on viscosity approximation methods for finite nonexpansive mappings are established in Banach spaces. The main theorem generalize the corresponding result of Kim and Xu [10] to the viscosity approximation method for finite nonexpansive mappings in a reflexive Banach space having a uniformly Gateaux differentiable norm. Our results also improve the corresponding results of [7, 8, 19, 20].

• 한국수학교육학회지시리즈B:순수및응용수학
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• 제30권1호
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• pp.25-34
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• 2023

Popa [14] proved the common fixed point theorem using implicit relations. Saluja [17] proved a fixed point theorem on complete partial metric spaces satisfying an implicit relation. In this paper, we prove a fixed point theorem on complete partial metric space satisfying another implicit relation.

• 한방재활의학과학회지
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• 제20권1호
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• pp.119-132
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• 2010

Objectives : The purpose of this study is to compare interrelations between stress and muscles of neck through stress response inventory(SRI), 7 zone diagnostic system and surface electromyography(sEMG). Methods : This study was carried out with the data from SRI, 7 zone diagnostic system and sEMG. First subjects were divided into two group according to the SRI points. subjects in group A had points of SRI in which lower than 30 points. Subjects in group B had points of SRI in which higher than 30 points. And subjects were divided into nonstress group(Group C) and stress grouop(Group D) according to the result of 7 zone diagnostic system. Then we investigated how to differentiate the muscle contraction, fatigue, recovery and asymmetry ratio on sEMG for each groups. Results : In this study, the muscle contraction of both upper trapezius muscle and left sternocleidomastoid muscle and left scalene muscle in stress group were higher than nonstress group significantly. And the muscle recovery of left sternocleidomastoid muscle and left scalene muscle in stress group were higher than nonstress group significantly. Conclusions : This results show that the stress was associated with muscle condition.

• 한국의류학회지
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• 제13권1호
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• pp.13-33
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• 1989

The purpose of this study is to obtain the effects on clothing weight in the health state of the kindergartners. So 1 divided 140 kindergartners into 3 groups. A not trained of light wearing in the control group, B the semi-experimetnal group, C the experimental group. In the field surveys conducted their monthly clothing weight and anthropometric measurements, physique index (obesity index) and motor-ability and rate of cold contraction and of absence, Cornell Medical index from Jun, 1986 to Feb, 1987 in Seoul. 1) The experimental group was even less clothing than the control group in clothing weight during the training period. 2) All the experimental group droped conspicuosly the rate of cold contraction and absence during this period. 3) After this training, the experimental group was better than semi-experimental group and control group in motor-ability especially in standing broad jump, flexibility and tennis ball throw, 25 meter dash. 4) But, 1 could not find the different of anthropometric-measurements, physique-index about this train.

• 산업기술연구
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• 제22권B호
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• pp.35-44
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• 2002

To find the optimal solution as rapidly and exactly as possible with Nelder-Mead simplex algorithm, the present values of the reflection, expansion, contraction and/or shrink parameters of this algorithm are needed to be changed at appropriate time during the search process. The reflection parameter is selected in this study in order to be changed because reflection, expansion and contraction process can be simultaneously effected by only this parameter. Two independent indices for determining whether the present value of the reflection parameter of this algorithm should be changed or not during the search process are suggested in this study. Those indices were made of the equations of Nelder-Mead simplex algorithm's convergence criterion and Dennis-Wood's convergence criterion, respectively. It is appeared that the optimal solution can be find with smaller numbers of objective function evaluation than the original Nelder-Mead's one with fixed parameter when the those indices are used during the search process. and the more remarkable reduction effect of the number of an objective function evaluation can be obtained when the latter index is used.

• Journal of Chest Surgery
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• 제24권4호
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• pp.421-427
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• 1991

Atrial fibrillation[Af] is closely related to thrombus in left atrium, systemic embolism, and loss of the contribution of atrial contraction to cardiac output. Therefore maintenance of sinus rhythm[SR] is undoubtedly hemodynamically superior to Af in the clinical course of mitral valvular disease especially in the unstable period immediately after surgery. In this article, the conversion rate and the factors influencing the conversion of Af to SR after surgery were studied. Ninety-three patients with mitral valvular replacement at Chungnam National University Hospital were analysed with electrocardiography before and after surgery during the period from June 1985 to June 1990. Eighty patients presented Af before surgery. Twenty-four[30Yo] of the patients were converted to SR[A group] and fifty six presented continuous Af after surgery[B group]. The duration of preoperative Af, preoperative left atrial dimension[LAD], preoperative functional status[NYHA classification] and cardiothoracic[CT] ratio were factors influencing the conversion of Af to SR after surgery. The mean preoperative duration of Af was 3.5$\pm$2.6yr in group A and 7.6$\pm$4.9yr in group B. The mean preoperative LAD was 53. 7$\pm$9.4mm in group A and 62.5$\pm$11.2mm in group B. Before surgery, eleven patients[46%] were belong to NYHA class I, II in group A and eight[14%] in group B. The preoperative CT ratio was 62$\pm$6% in group A and 69$\pm$8% in group B.

• Molecules and Cells
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• 제20권1호
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• pp.51-56
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• 2005

Excitation-contraction coupling (ECC) proteins in the human heart were characterized using human atrial tissues from different age groups. The samples were classified into one infant group (Group A: 0.2-7 years old) and three adult groups (Group B: 21-30; Group C: 41-49; Group D: 60-66). Whole homogenates (WH) of atrial tissues were assayed for ligand binding, $^{45}Ca^{2+}$ uptake and content of ECC proteins by Western blotting. Equilibrium [$^3H$]ryanodine binding to characterize the ryanodine receptor (RyR) of the sarcoplasmic reticulum (SR) showed that the maximal [$^3H$]ryanodine binding ($B_{max}$) to RyR was similar in all the age groups, but the dissociation constant ($k_d$) of ryanodine was higher in the infant group than the adult groups. Oxalate-supported $^{45}Ca^{2+}$ uptake into the SR, a function of the SR SERCA2a activity, was lower in the infant group than in the adult groups. Similarly, [$^3H$]PN200-110 binding, an index of dihydropyridine receptor (DHPR) density, was lower in the infant group. Expression of calsequestrin and triadin assessed by Western blotting was similar in the infant and adult groups, but junctin expression was considerably higher in the adult groups. These differences in key ECC proteins could underlie the different $Ca^{2+}$ handling properties and contractility of infant hearts.

• Journal of the Korean Wood Science and Technology
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• 제46권6호
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• pp.656-669
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• 2018

Tropical bamboo species, which have a very rapid growth rate, are considered as a promising non-timber forest product capable of exhibiting new functionality by carbonization technology. This study was conducted to compare the characteristics of carbonized bamboos from Andong (G. pseuudoarundinacea (Steudel) Widjaja), Hitam (G. atrovialacea), Tali (G. apus), Kuning (B. vulgaris Var. striata (Lodd. Ex Lindl)), and Ampel (B. vulgaris Scharad. ex Wendland), and Betung (D. asper). Each bamboo was carbonized at 200, 400, 600, 800, and $1,000^{\circ}C$, respectively, and their physical and anatomical characteristics were investigated. The result showed that the volume and weight of carbonized bamboo decreased with increasing carbonization temperature and showed the substantial changes of volume and weight between 200 and $400^{\circ}C$. The highest and the lowest density of carbonized samples were found in Ampel bamboo and Betung bamboo, respectively. The density of all carbonized bamboos tended to decrease after carbonization at 200 and $400^{\circ}C$ and relatively become constant afterwards. The carbonized bamboo prepared at 800 and $1,000^{\circ}C$ showed better refining degree. The results of the anatomical observation showed that the vascular diameter of carbonized bamboo decreased with increasing carbonization temperature, and the shrinkage in radial and tangential direction showed similar tendency. Statistical analysis showed that there was significant correlation between physical contraction and anatomical contraction. Based on the results of this study, comprehensive data about Indonesian bamboo charcoals could be obtained and it will be useful for future application studies.

• Molecules and Cells
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• 제27권3호
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• pp.383-390
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• 2009

To investigate the regulatory mechanism underlying the contractile response in the intestinal smooth muscle of the nile tilapia (Orechromis niloticus), we used pharmacologic and molecular approaches to identify the muscarinic subreceptors and the intracellular signaling pathways involved in this motility. Myography assays revealed that an M1- and M3-subtype selective antagonist, but not a M2-subtype selective antagonist, inhibited carbachol HCl (CCH)-induced intestinal smooth muscle contraction. In addition, a phospholipase C inhibitor, but not an adenylate cyclase inhibitor, blocked the contractile response to CCH. We also cloned five muscarinic genes (OnM2A, OnM2B, OnM3, OnM5A, and OnM5B) from the nile tilapia. In the phylogenetic analysis and sequence comparison to compare our putative gene products (OnMs) with the sequences obtained from the near complete teleost genomes, we unexpectedly found that the teleost fish have respectively two paralogous genes corresponding to each muscarinic subreceptor, and other teleost fish, except zebrafish, do not possess muscarinic subreceptor M1. In addition, the expression pattern of the nile tilapia muscarinic subreceptor transcripts during CCH-induced intestinal smooth muscle contraction in the proximal intestinal tissue was analyzed by real-time PCR surveys and it was demonstrated that CCH increased the OnMs mRNA expression rapidly and transiently.