• Title/Summary/Keyword: B-Class

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Leptomycin B Increases Radiosensitization by Trichostain A in HeLa Cells (HeLa세포주에서 Leptomicin B에 의한 Trichostain A의 방사선 감작효과의 증가)

  • Kim, In-An;Kim, Jin-Ho;Shin, Jin-Hee;Kim, Il-Han;Kim, Jae-Sung;Wu-Hong, Gyun;Chie, Eui-Kyu;Kim, Yong-Ho;Kim, Bo-Kyung;Hong, Se-Mie;Ha, Sung-Whan;Park, Chan-Il
    • Radiation Oncology Journal
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    • v.23 no.2
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    • pp.116-122
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    • 2005
  • Purpose: Histone deacetylase inhibitors (HDIs) are emerging as potentially useful components of anticancer therapy and their radiosensitizing effects have become evident. Specific HDAS are now available that preferentially inhibit specific HDAC classes; TSA inhibits Class I and II HDACs, and SK7041 inhibits Class I HDACs. Materials and methods: We tested the differential radiosensitization induced by two different classes of HDIs in HeLa cells. We next tested the hypothesis that p53 expression in cancer cells may influence the susceptibility to HDIs by using pharmacologic modification of the p53 status under an isogenic background. Results: It is interesting that p53 expression in the HeLa cells clearly increased the degree of radio-sensitization by TSA compared to that of the class I specific inhibitor SK7041. This suggests that p53 may, in part, be responsible for the mechanistic role for the greater radiosensitization induced by Class I & II inhibitors compared to that of the class I specific inhibitors. Thus, these studies are useful in distinguishing between events mediated solely by the Class I HDACS versus those events involving the other classes of HDACS as well. Conclusion: The anticancer efficacy of targeting Class I and II HDACS, in conjunction with radiation therapy, may be further enhanced by the restoration of p53 expression.

MULTIPLE Lp ANALYTIC GENERALIZED FOURIER-FEYNMAN TRANSFORM ON A FRESNEL TYPE CLASS

  • Chang, Seung Jun;Lee, Il Yong
    • Journal of the Chungcheong Mathematical Society
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    • v.19 no.1
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    • pp.79-99
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    • 2006
  • In this paper, we define a class of functional defined on a very general function space $C_{a,b}[0,T]$ like a Fresnel class of an abstract Wiener space. We then define the multiple $L_p$ analytic generalized Fourier-Feynman transform and the generalized convolution product of functionals on function space $C_{a,b}[0,T]$. Finally, we establish some relationships between the multiple $L_p$ analytic generalized Fourier-Feynman transform and the generalized convolution product for functionals in $\mathcal{F}(C_{a,b}[0,T])$.

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A Study on Linearity and Efficiency Enhancement of Power Amplifier (전력증폭기의 선형성 및 효율 향상에 관한 연구)

  • Jeon Joong-Sung
    • Journal of Advanced Marine Engineering and Technology
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    • v.29 no.6
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    • pp.618-627
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    • 2005
  • In this paper, we have compared and analyzed the performance of high amplifier using Doherty technique to improve linearity and efficiency of base station and repeater Power amplifier for WCDMA. This Doherty amplifier implements with 3dB branch line coupler and $90^{\circ}C$ transmission line The phase offset line is designed to maintain the high linearity and efficiency at the low efficiency Period of the power amplifier CW 1-tone experimental results at the WCDMA frequency $2.11{\sim}2.17GHz$ shows that Doherty amplifier which achieves power add efficiency(PAE) of 50% at 6dB back off the point from maximum output power 52.3 dBm, obtains higher efficiency of 13.3% than class AB Finding optimum bias Point after adjusted gate voltage, Doherty amplifier shows that $IMD_3$ improves 4dB.

STRUCTURAL PROJECTIONS ON A JBW-TRIPLE AND GL-PROJECTIONS ON ITS PREDUAL

  • Hugli, Remo-V.
    • Journal of the Korean Mathematical Society
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    • v.41 no.1
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    • pp.107-130
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    • 2004
  • A $JB^{*}-triple$ is a Banach space A on which the group Aut(B) of biholomorphic automorphisms acts transitively on the open unit ball B of A. In this case, a triple product {$\cdots$} from $A\;\times\;A\;\times\;A\;to\;A$ can be defined in a canonical way. If A is also the dual of some Banach space $A_{*}$, then A is said to be a JBW triple. A projection R on A is said to be structural if the identity {Ra, b, Rc} = R{a, Rb, c, }holds. On $JBW^{*}-triples$, structural projections being algebraic objects by definition have also some interesting metric properties, and it is possible to give a full characterization of structural projections in terms of the norm of the predual $A_{*}$ of A. It is shown, that the class of structural projections on A coincides with the class of the adjoints of neutral GL-projections on $A_{*}$. Furthermore, the class of GL-projections on $A_{*}$ is naturally ordered and is completely ortho-additive with respect to L-orthogonality.

A CHARACTERIZATION OF ZERO DIVISORS AND TOPOLOGICAL DIVISORS OF ZERO IN C[a, b] AND ℓ

  • Harish Chandra;Anurag Kumar Patel
    • Communications of the Korean Mathematical Society
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    • v.38 no.2
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    • pp.451-459
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    • 2023
  • We give a characterization of zero divisors of the ring C[a, b]. Using the Weierstrass approximation theorem, we completely characterize topological divisors of zero of the Banach algebra C[a, b]. We also characterize the zero divisors and topological divisors of zero in ℓ. Further, we show that zero is the only zero divisor in the disk algebra 𝒜 (𝔻) and that the class of singular elements in 𝒜 (𝔻) properly contains the class of topological divisors of zero. Lastly, we construct a class of topological divisors of zero of 𝒜 (𝔻) which are not zero divisors.

A Study on Isolation Improvement of LTE-PIFA Used Stub Structure on Ground Plane (접지면 위의 스터브를 이용한 LTE-PIFA의 격리도 개선 연구)

  • Park, Chan-Jin;Min, Kyoeng-Sik
    • The Journal of Korean Institute of Electromagnetic Engineering and Science
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    • v.24 no.4
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    • pp.374-383
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    • 2013
  • This paper presents a design for improvement of isolation characteristics by the inserted stub structure on ground plane of a handy terminal which is composed of a main antenna and a sub antenna covered LTE bandwidth. In order to compensate for a resonance length of proposed antenna and to realize a high isolation characteristic, a pair of stub was inserted and located on ground plane that currents from two antennas were converged. A simulated isolation characteristic of antenna without stub at the LTE class 13 band was about -5 dB, but its characteristics of proposed antenna with two stubs at uplink(777~787 MHz) and downlink(746~756 MHz) of the LTE class 13 band were about -12 dB and -15 dB, respectively. An average gain of a fabricated antenna with two stubs was observed about -2 dBi above and it showed good results with comparison of business condition that the average gain of commercial handy terminal has to appear -4 dBi above. The measured S-parameter characteristics and radiation patterns showed a reasonable agreement with the simulation results.

A Design of High Efficiency Doherty Power Amplifier for Microwave Applications (마이크로파용 고효율 Doherty 전력증폭기 설계)

  • Oh Jeong-Kyun;Kim Dong-Ok
    • Journal of Navigation and Port Research
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    • v.30 no.5 s.111
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    • pp.351-356
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    • 2006
  • In this paper, the high efficiency Doherty power amplifier has been designed and realized for microwave applications. The Doherty amplifier has been implemented using silicon MRF 281 LDMOS FET. The RF performances cf the Doherty power amplifier (a combination of a class AB carrier amplifier and a bias-tuned class C peaking amplifier) have been compared with those of a class AB amplifier alone. The realized Doherty power amplifier P1dB output power has 33dBm at 2.3GHz frequency. Also the Doherty power amplifier shows 11dB gain and -17.8dB input return loss at 2.3GHz to 2.4GHz. The designed Doherty amplifier has been improved the average PAE by 10% higher efficiency than a class AB amplifier alone. The Maximum PAE of designed Doherty power amplifier has been 39%.

A Design of High Efficiency Doherty Power Amplifier for Microwave applications (마이크로파용 고효율 Doherty 전력 증폭기 설계)

  • Oh C.G.;Kim D.O.
    • Proceedings of the Korean Institute of Navigation and Port Research Conference
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    • 2006.06b
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    • pp.91-96
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    • 2006
  • In this paper, the high efficiency Doherty power amplifier has been designed and realized for microwave applications. The Doherty amplifier has been implemented using silicon MRF 281 LOMOS FET. The RF performances of the Doherty power amplifier (a combination of a class AB carrier amplifier and a bias..tuned class C peaking amplifier) have been compared with those of a class AB amplifier alone. The realized Doherty power amplifier PldB output power has 33dBm at 2.3GHz frequency. Also the Doherty power amplifier shows 11dB gain and -17.8dB input return loss at 2.3GHz to 2.4GHz. The designed Doherty amplifier has been improved the average PAE by 10% higher efficiency than a class AB amplifier alone. The Maximum PAE of designed Doherty power amplifier has been 39%.

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A Study on Efficiency Extension of a High Power Doherty Amplifier Using Unequal LDMOS FET's (불 균등한 LDMOS FET를 이용한 고 출력 도허티 증폭기의 효율 확장에 관한 연구)

  • Hwang, In-Hong;Kim, Jong-Heon
    • Proceedings of the Korea Electromagnetic Engineering Society Conference
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    • 2005.11a
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    • pp.81-86
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    • 2005
  • In this paper, we present an efficiency extension of Doherty power amplifier using LDMOS FET devices with different peak output powers and an unequal power divider. The amplifier is designed by using a MRF21045 with P1 dB of 45 W as the main amplifier biased for Class-AB operation and a MRF21090 with P1 dB of 90 W as the peaking amplifier biased for Class-C operation. The input power is divided into a 1:1.5 power ratio between the main and peaking amplifier. The simulated results of the proposed Doherty amplifier shows an efficiency improvement of approximately 19 % in comparison to the class-AB amplifier at an output power of 42.5 dBm. The fabricated Doherty amplifier obtained a PAE of 33.68 % at 9 dB backed off from P1 dB of 51.5 dBm.

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