• 디지털융복합연구
• /
• 제17권3호
• /
• pp.261-269
• /
• 2019

본 연구는 우리나라의 종합병원의 경영성과와 지역 의료이용 친화도를 알 수 있는 RI를 과학적인 방법으로 산출하여 지역의료이용량과 병원 경영성과의 인과 관계에 대한 연구결과를 바탕으로 효율적인 경영전략을 제시하는데 그 연구의 의의가 있다. 연구결과를 보면 첫째, 일반적 특성에 따른 지역친화도 차이에서는 도시구분별 병상 수, 경상이익에서 통계적으로 유의한 차이가 나타났다. 둘째, 지역 의료이용의 친화도(RI)와 변수들 간의 상관관계를 살펴보면, 경상수지비율, 외래환자 초진율, 의료수익의료이익률, 100병상 당 1일 평균 외래환자 수, 100병상 당 1일 평균 입원환자 수, 입원환자 1인 1일당 평균진료비와 유의한 상관관계를 나타냈다. 연구결과를 바탕으로 본 연구의 의의를 살펴보면, 첫째 지역 의료이용 지표인 지역 의료이용 친화도를 산출하여 경영성과와의 연관관계와 유의한 영향을 미치는 변수를 규명하였다는 점에서 본 연구의 의의가 있다고 할 수 있다. 둘째로는 도시규모, 병상규모 등 내,외부적 환경요인에 따라 비교분석하였으며, 향후 병원이 지역 의료이용률를 높이기 위한 병원경영 전략의 수립에 기초 자료를 제공하였다고 할 수 있다.

• Wind and Structures
• /
• 제28권2호
• /
• pp.71-87
• /
• 2019

The yaw and interference effects of blades affect aerodynamic performance of large wind turbine system significantly, thus influencing wind-induced response and stability performance of the tower-blade system. In this study, the 5MW wind turbine which was developed by Nanjing University of Aeronautics and Astronautics (NUAA) was chosen as the research object. Large eddy simulation on flow field and aerodynamics of its wind turbine system with different yaw angles($0^{\circ}$, $5^{\circ}$, $10^{\circ}$, $20^{\circ}$, $30^{\circ}$ and $45^{\circ}$) under the most unfavorable blade position was carried out. Results were compared with codes and measurement results at home and abroad, which verified validity of large eddy simulation. On this basis, effects of yaw angle on average wind pressure, fluctuating wind pressure, lift coefficient, resistance coefficient,streaming and wake characteristics on different interference zone of tower of wind turbine were analyzed. Next, the blade-cabin-tower-foundation integrated coupling model of the large wind turbine was constructed based on finite element method. Dynamic characteristics, wind-induced response and stability performance of the wind turbine structural system under different yaw angle were analyzed systematically. Research results demonstrate that with the increase of yaw angle, the maximum negative pressure and extreme negative pressure of the significant interference zone of the tower present a V-shaped variation trend, whereas the layer resistance coefficient increases gradually. By contrast, the maximum negative pressure, extreme negative pressure and layer resistance coefficient of the non-interference zone remain basically same. Effects of streaming and wake weaken gradually. When the yaw angle increases to $45^{\circ}$, aerodynamic force of the tower is close with that when there's no blade yaw and interference. As the height of significant interference zone increases, layer resistance coefficient decreases firstly and then increases under different yaw angles. Maximum means and mean square error (MSE) of radial displacement under different yaw angles all occur at circumferential $0^{\circ}$ and $180^{\circ}$ of the tower. The maximum bending moment at tower bottom is at circumferential $20^{\circ}$. When the yaw angle is $0^{\circ}$, the maximum downwind displacement responses of different blades are higher than 2.7 m. With the increase of yaw angle, MSEs of radial displacement at tower top, downwind displacement of blades, internal force at blade roots all decrease gradually, while the critical wind speed decreases firstly and then increases and finally decreases. The comprehensive analysis shows that the worst aerodynamic performance and wind-induced response of the wind turbine system are achieved when the yaw angle is $0^{\circ}$, whereas the worst stability performance and ultimate bearing capacity are achieved when the yaw angle is $45^{\circ}$.

• 한국습지학회지
• /
• 제20권4호
• /
• pp.417-423
• /
• 2018

축산 지역 하류에 위치한 농업용 저수지의 강우시 유입, 유출수 분석을 통해 축산지역의 강우 유출 특성과 저류지에 의한 축산계 비점 오염물질의 저류형 시설에 의한 유출 저감 효율을 분석하였다. 급경사지에 위치한 한우 축산 지역의 비점 오염물질 유출은 주로 초기세척현상에 의해 발생됨을 알 수 있었으며 강우시의 유입수 농도는 비강우시에 비해 SS농도가 가장 높게 발생하고 있으며 T-P도 4배 이상 증가하는 양상을 보인다. 반면 총질소는 평균 30% 증가하는 것으로 나타나는데 질소항목으로 보면 질산성 질소는 거의 변화가 없는 반면에 암모니아성 질소가 2배 이상 증가하고 있다. 저류형 비점 제거시설 효율 분석 결과 비강우시 총인 제거효율이 53%로 가장 높고 부유물질은 37% 제거되고 있다. 유기물질은 10% 내외, 총질소는 5% 이내로 제거되며 부영양화로 녹조가 번성하는 하절기에는 오히려 유출수의 질소농도가 더 높아지는 경우도 빈번히 발생하고 있다. 강우시의 유입수 농도는 비강우시에 비해 SS농도가 가장 높게 발생하고 있으며 T-P도 4배 이상 증가하는 양상을 보인다. 강우시 부유물질의 제거효율은 60%로 나타나고 있으며 총인은 22% 제거되어 비강우시에 비해 제거효율은 감소하고 있다. 환경부의 비점제거시설 기준보다 9배 이상의 용량을 지니고 있지만 비점 전용 시설로 활용되지 못하는 탓에 장마철에 거의 만수 상태로 담수하여 비점제거 효율에 있어서는 충분한 효과를 보이지 못하고 있는 것으로 나타나 저수지의 용량 뿐 아니라 수문관리 등 유지관리도 비점 제거효율에 영향을 미치는 중요 인자로 분석되었다.

• Journal of Animal Science and Technology
• /
• 제61권1호
• /
• pp.1-9
• /
• 2019

Little is known about the effects of the plane of nutrition on growth performance and meat quality of grow-finish pigs under commercial production conditions. The present study was thus addressed to this virtually unanswered question. One hundred and two barrows and 102 gilts weighing approximately 24 kg were fed phase I and II grower diets with a high, medium, or low plane of nutrition (HP, MP, or LP) to approximately 43 and 70 kg, respectively, in 6 replicates (pens). Subsequently, the HP and MP groups were fed the HP and MP1 finisher diets, respectively, the LP group being fed a second MP (MP2) finisher diet (LP1 group). Moreover, 68 LP-grower-fed barrows and gilts were added to the feeding trial and fed the MP1 and LP finisher diets to approximately 95 kg and thereafter, respectively (LP2 group). All MP diets had the lysine:calorie ratios comparable to the RNC recommendations, with < 18% differences between those of the HP and LP diets. The finisher pigs were reared in 16 pens and slaughtered at approximately 115 kg. The gain:feed ratio, but not average daily gain (ADG), was greater for the HP group than for the MP and LP during the grower phase I whereas during the grower phase II, ADG was greater (p < 0.05) for the HP and LP groups vs. MP. During the finisher phase I, ADG was less for the LP (LP1 + LP2) group vs. HP and MP, with no difference between the HP and MP groups; the gain:feed ratio was less for the LP vs. MP group. Backfat thickness was greater for the LP vs. HP group. The water holding capacity of fresh longissimus dorsi muscle (LM) and the sensory juiciness score for cooked LM were greatest for the LP group, the sensory flavor and tenderness scores being greater for the LP group vs. MP. In conclusion, results suggest that compensatory growth occurred for the LP and MP groups during the grower phase II and finisher phase I, respectively, with fat deposition increased for the LP group and that meat quality could be improved by the use of LP.

• Nutrition Research and Practice
• /
• 제13권4호
• /
• pp.302-309
• /
• 2019

BACKGOURND/OBJECTIVES: Vascular inflammation is an important feature in the atherosclerotic process. Recent studies report that leaves and branches of Carpinus turczaninowii (C. turczaninowii) have antioxidant capacity and exert anti-inflammatory effects. However, no study has reported the regulatory effect of C. turczaninowii extract on the arterial inflammatory response. This study therefore investigated modulation of the arterial inflammatory response after exposure to C. turczaninowii extract, using human aortic vascular smooth muscle cells (HAoSMCs). MATERIALS/METHODS: Scavenging activity of free radicals, total phenolic content (TPC), cell viability, mRNA expressions, and secreted levels of cytokines were measured in LPS-stimulated (10 ng/mL) HAoSMCs treated with the C. turczaninowii extract. RESULTS: C. turczaninowii extract contains high amounts of TPC ($225.6{\pm}21.0mg$ of gallic acid equivalents/g of the extract), as well as exerts time-and dose-dependent increases in strongly scavenged free radicals (average $14.8{\pm}1.97{\mu}g/mL$ $IC_{50}$ at 40 min). Cell viabilities after exposure to the extracts (1 and $10{\mu}g/mL$) were similar to the viability of non-treated cells. Cytokine mRNA expressions were significantly suppressed by the extracts (1 and $10{\mu}g/mL$) at 6 hours (h) after exposure. Interleukin-6 secretion was dose-dependently suppressed 2 h after incubation with the extract, at $1-10{\mu}g/mL$ in non-stimulated cells, and at 5 and $10{\mu}g/mL$ in LPS-stimulated cells. Similar patterns were also observed at 24 h after incubation with the extract (at $1-10{\mu}g/mL$ in non-stimulated cells, and at $10{\mu}g/mL$ in the LPS-stimulated cells). Soluble intracellular vascular adhesion molecules (sICAM-1) secreted from non-stimulated cells and LPS-stimulated cells were similarly suppressed in a dose-dependent manner after 24 h exposure to the extracts, but not after 2 h. In addition, sICAM-1 concentration after 24 h treatment was positively related to IL-6 levels after 2 h and 24 h exposure (r = 0.418, P = 0.003, and r = 0.524, P < 0.001, respectively). CONCLUSIONS: This study demonstrates that C. turczaninowii modulates the arterial inflammatory response, and indicates the potential to be applied as a therapeutic use for atherosclerosis.

• Asian-Australasian Journal of Animal Sciences
• /
• 제32권4호
• /
• pp.585-591
• /
• 2019

Objective: This study investigated carcass characteristics and meat quality of purebred Pakchong 5, crossbred pigs sired by Pakchong 5, and crossbred pigs sired by Duroc. Methods: Forty-eight pigs (average body weight of 22.25 kg) were composed of three groups as purebred Pakchong 5 (PP), Large $White{\times}Landrace$ pigs sired by Pakchong 5 (LWLRP), and Large $White{\times}Landrace$ pigs sired by Duroc (LWLRD). Each group consisted of eight gilts and eight barrows. At 109-day-raising period, pigs were slaughtered, and carcass characteristics were evaluated. Longissimus thoracis (LT) muscles from left side of carcasses were evaluated for meat quality and chemical composition. Data were analyzed using general linear model procedure, where group, sex, and their interaction were included in the model. Results: The PP had greater carcass, total lean, and ham percentages than crossbred pigs (p<0.05). LWLRP had thicker backfat and more carcass fat percentage than LWLRD (p<0.05). There were no differences (p>0.05) on cutting percentages from tender loin, loin, boston butt, and picnic shoulder among groups. The PP and LWLRP had larger loin eye area (LEA) than LWLRD (p<0.05). Gilts had more loin percentage and lower $L^*$ value than barrows (p<0.05). No meat color parameters ($L^*$, $a^*$, and $b^*$) were affected by groups (p>0.05). PP and LWLRP had larger muscle fiber diameters than LWLRD (p<0.05). However, water holding capacity, Warner-Bratzler shear force values, and chemical composition of LT were not affected by group or sex (p>0.05). Conclusion: Pakchong 5 purebred has good carcass and lean percentages. Compared to Duroc crossbred pigs, Pakchong 5 crossbreds have similar carcass and lean percentages, larger LEA, and slightly more carcass fat, with comparable meat quality and chemical composition. Pakchong 5 boars are more affordable for very small- to medium-scale pig producers.

• 한국수자원학회논문집
• /
• 제52권4호
• /
• pp.235-243
• /
• 2019

급격한 기상변화로 인한 극한 강우와 집중폭우의 발생빈도 증가로 기존 수방시설의 한계 용량을 초과해 도심지 침수피해가 빈번하게 발생하고 있다. 최근 도시화 추세가 급격하게 빨라지면서 수방시설 등 사회기반시설에 대한 지하공간 개발의 필요성이 증가하고 있으며, 지하공간을 활용한 지하방수로와 지하저류지 기술이 급부상하고 있다. 본 연구에서는 지하유입시설의 대표적 형상인 접선식 유입구와 나선식 유입구에 대한 공기 배출효과를 분석하기 위해 유입유량 변화에 따른 수직갱 내부 공기공동(air-core)의 형상 크기를 계측했다. 나선식 유입구의 경우, 저유량 유입조건에서 와류 유도 효과를 개선하기 위해 유입부 바닥면에 계단형 다단식 구조를 도입했다. 수직갱 내부 공기공동의 전체적인 평균 단면적의 경우, 다단식 나선 유입구가 접선식 유입구보다 10% 정도 크게 나타나 고유량 유입조건에서 높은 공기 배출 효과와 유입효율을 나타냈다. 접선식 유입구의 경우, 유입구가 가지는 고유 성능을 유지할 수 있는 최대 유량 조건을 초과하면서 공기 배출 효과가 감소하기 시작했다. 또한, 실험에서 사용된 접선식 유입구와 다단식 나선 유입구 모형에 활용 가능한 기초자료를 제공하기 위해 수직갱 내부 위치에 따른 공기공동 단면적에 대한 실험식(empirical formula)을 제시했다.

• 한국지반공학회논문집
• /
• 제37권9호
• /
• pp.25-36
• /
• 2021

최근 토공사 품질관리를 위한 지능형 다짐 기술이 토공사 품질관리 기준으로 주목받고 있다. 본 연구에서는 지능형 다짐기술과 이를 활용한 토공사 품질관리 기준을 분석하고, 현장시험을 통해 지능형 다짐기술을 활용한 토공사 품질관리 시험시공 절차에 대해 고찰하였다. 실트질 모래(SM) 성토재의 현장다짐시험을 통해 다짐 횟수가 증가할수록 CMV와 기존의 다짐품질 시험결과 값이 증가하는 상관성을 확인하였다. 시험시공 데이터를 토대로 평균 CMV 및 품질관리 목표 CMV 도출을 하였다. 평판재하시험 지지력계수와 상관성 통해 목표 CMV(34.2)와 CMV 증가율 분석방법을 통해 목표 CMV(36.6)를 산정하였다. 본 논문을 통해 지능형 다짐기술을 이용한 현장 다짐 품질관리 절차 및 방법론에 대하여 논의하였으며, 아울러 해당 기술의 국내 적용 가능성을 고취시키기 위한 지능형 다짐 품질관리 방안을 제언하였다.

• 자원환경지질
• /
• 제54권2호
• /
• pp.259-269
• /
• 2021

국내 69개 농경지 토양 내 Cd, Cr, Cu, Ni, Pb, Zn을 대상으로 하여 토양 pH, 양이온교환능력, 유기물 함량 등의 물리화학적 특성이 CaCl2, HOAc, HNO3, DTPA 등을 이용한 중금속의 단일용출 결과에 미치는 영향을 통계학적으로 조사하였다. 통계학적 분석은 토양의 물리화학적 특성의 평균값을 기준으로 높고 낮은 두 표본으로 구분한 후 이에 대해 상관분석과 다중회귀분석을 수행하였다. Cr, Cu, Ni, Pb의 경우 HNO3를 적용하였을 때 다른 추출제에 비하여 높은 함량이 추출되었으나, Cd, Zn의 경우 HOAc를 이용한 추출에서도 유사한 함량이 추출되었다. 상관관계 조사 결과, DTPA 추출이 다른 단일용출 및 전함량과 상관관계가 높았으며, 토양의 물리화학적 특성이 단일용출 결과에 영향을 미치는 것으로 나타났다. Zn의 경우, 전함량과 모든 단일용출법들에 의한 추출 함량이 상호 높은 상관관계를 보였다. 회귀분석 결과, 토양의 물리화학적 특성은 최대 74%에 이르는 단일용출 결과의 분산을 설명할 수 있는 것으로 나타났다. 이러한 결과는 토양의 물리화학적 특성이 단일용출 결과에 직접적인 영향을 미칠 수 있음을 나타낸다.

• Journal of Microbiology and Biotechnology
• /
• 제31권2호
• /
• pp.207-216
• /
• 2021

Supplement of high-protein food plays an important role in improving the symptoms of malnutrition and the immune capacity of the body, but the association of high-protein diet and gut microbiota remained unaddressed. Here, we systematically analyzed the internal organs and gut microbiota in C57(WT) or PD-1H-depleted (KO) mice (T cells were activated) fed with pupae or feed for six weeks. We observed that the body weight gain in the mice fed with pupae increased less significantly than that of the feed group, while the villi and small intestine lengths in the pupa group were reduced compared with that of mice given feed. However, the average body weight of the KO mice increased compared with that of the WT mice fed with pupae or feed. Pupae increased the concentration of blood glucose in WT, but not in KO mice. Moreover, in the feed group, there was no difference in the weight of the internal organs between the WT and KO mice, but in the pupae-fed group, liver weight was decreased and spleen weight was increased compared with that of KO mice. The amounts/plural/amounts of Melainabacteria, Chloroflexi, and Armatimonadetes were specifically upregulated by pupae, and this upregulation was weakened or eliminated by PD-1H depletion. Some bacteria with high abundance in the feed-fed KO mice, such as Deferribacteres, Melainabacteria, Acidobacteria, Bacteroidetes, Spirochaetes and Verrucomicrobia, were decreased in pupae-fed KO mice, and Proteobacteria and Deinococcus were specifically enriched in pupae-fed KO mice. Bacteroidetes, Firmicutes and Akkermansia were associated with weight loss in the pupae-fed group while Lachnospiraceae and Anaerobiospirillum were related glucose metabolism and energy consumption. Based on high-throughput sequencing, we discovered that some gut bacteria specifically regulated the metabolism of a high-protein diet, and PD-1H deficiency improved life quality and sustained blood glucose. Moreover, PD-1H responses to high-protein diet through modulating the type and quantity of gut bacteria. These findings provide evidence about the association among gut microbiota, T cell activation (for PD-1H depletion) and high-protein diet metabolism, have important theoretical significance for nutrition and health research.