• Proceedings of the Computational Structural Engineering Institute Conference
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• 1999.10a
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• pp.143-150
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• 1999

The LRFD Specification defines two sets of limiting width-to-thickness ratios. On the basis of these limiting values, steel sections we subdivided into three categories: compact, noncompact, and slender sections. A compact section is capable of developing a fully plastic stress distribution (plastic moment), and can sustain rotations approximately three times beyond the yield before the possibility of local buckling arises. Noncompact sections can develop the yield stress before local buckling occurs. They may not, however, resist local buckling at the strain levels required to develop the fully plastic stress distribution. In this paper, 1-Type girders of a 2 span continuous steel bridge are divided into compact and non-compact sections and analyzed. In the design process, an optimization skill was adopted and ADS, a Fortran program for Automated Design Synthesis, was used.

• Proceedings of the Korean Institute of Intelligent Systems Conference
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• 1993.06a
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• pp.785-788
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• 1993

This paper presents the prototype framework for automated integration of CMOS current-mode fuzzy logic circuits using an intelligent module approach. The library of modules representing the standard fuzzy logic operators was built. These modules were finally used to synthesized sophisticated fuzzy logic units. Fuzzy unit designs were made based upon the results of a newel methodology of the current mirror-based fuzzy logic function synthesis. This methodology is actually incorporated into the presented framework. As an example, the membership function unit was synthesized, simulated, and the final layout was generated using the presented framework. Finally, the fuzzy logic controller unit (FLC) was generated using the proposed framework. Simulation as well as measurement results show unquestionable advantages of the proposed fuzzy logic function integration system over the classical design methodology with respect to the area, relative error and performance.

• Journal of Ship and Ocean Technology
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• v.5 no.1
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• pp.14-29
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• 2001

Concept and preliminary structural design methods, including large scale FEM analysis and optimisation, for large passenger ships, car passenger and RoRo/ passenger ships are dis-cussed. Applications and experiences in practical design usage are presented.

• International Journal of Computer Science & Network Security
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• v.22 no.5
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• pp.168-174
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• 2022

The article defines the organizational conditions for effective management, the actions of the team to implement the concept of marketing management using the tools of pedagogical and strategic management. Due to this, results are achieved - indicators, since in our study they will be indicators of managerial efficiency: improving the "organization" function through the construction of new organizational structures; improving the functions of "analytical activity and planning" through enriching managerial work with economic and gnostic methods, analytical activities with the mandatory inclusion of financial activities, introspection of all participants, widespread use of licensed automated systems; synthesis of educational, economic, social results.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.23
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• pp.10057-10059
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• 2015

Positron emission tomography (PET) as the functional component of current hybrid imaging (like PET/CT or PET/MRI) seems to dominate the horizon of medical imaging in coming decades. $^{18}$Flourodeoxyglucose ($^{18}FDG$) is the most commonly used probe in oncology and also in cardiology and neurology around the globe. However, the major capital cost and exorbitant running expenditure of low to medium energy cyclotrons (about 20 MeV) and radiochemistry units are the seminal reasons of low number of cyclotrons but mushroom growth pattern of PET scanners. This fact and longer half-life of $^{18}F$ (110 minutes) have paved the path of a centralized model in which $^{18}FDG$ is produced by commercial PET radiopharmacies and the finished product (multi-dose vial with tungsten shielding) is dispensed to customers having only PET scanners. This indeed reduced the cost but has limitations of dependence upon timely arrival of daily shipments as delay caused by any reason results in cancellation or rescheduling of the PET procedures. In recent years, industry and academia have taken a step forward by producing low energy, table top cyclotrons with compact and automated radiochemistry units (Lab-on-Chip). This decentralized strategy enables the users to produce on-demand doses of PET probe themselves at reasonably low cost using an automated and user-friendly technology. This technological development would indeed provide a real impetus to the availability of complete set up of PET based molecular imaging at an affordable cost to the developing countries.

• Journal of the Korean Society of Hazard Mitigation
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• v.10 no.3
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• pp.31-38
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• 2010

In this study, it is suggested that it has to reliability-based design methodology with respect to bridge structure-rail longitudinal interaction and bridge structure-vehicle interaction. For the structural analysis, commercial package, ABAQUS, are used for a three-dimensional finite element analysis. The optimization process utilizes a well-known optimizer, ADS(Automated Design Synthesis). Optimization technique is utilized the ALM-BFGS method for global area search and Golden Section Method for 1-D search. In general, ALM-BFGS method don't need the 1-D search, and that algorithm converge a 0.1~0.2 of Push-Off factor. But in this study, value of Push-Off factor is used 90, therefore 1-D search should be needed for effective convergency. That algorithm contains the "heuristic decision method". As a result of optimum design of 2-main steel girder birdge with 5${\times}$(1@50m), design methodology suggested in this study was demonstrated more economic and efficient than existing design and LCC optimization not considering bridge-rail longitudinal interaction and bridge-vehicle interaction.

• Journal of Radiopharmaceuticals and Molecular Probes
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• v.2 no.2
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• pp.123-131
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• 2016

Increasing clinical demand for carbon-11 labeled radiopharmaceuticals has triggered technological advances in fields of radiochemistry and automated modules. Even though carbon-11 has a short half-life ($t_{1/2}=20.4min$), the consecutive second production of carbon-11 labeled radiopharmaceutical in one $^{11}C$-synthetic module should be delayed at least over 4 h to avoid the high radiation exposure. We herein aimed to produce two different carbon-11 labeled radiopharmaceuticals ([$^{11}C$]PIB and [$^{11}C$]methionine) by sharing of [$^{11}C$]methylation source in one $^{11}C$-synthetic module. The synthesis of $^{11}C$-labeling reagents ($[^{11}C]CH_3I$ or $[^{11}C]CH_3OTf$) is fully automated using the commercial TRACERlab $FX_{C-pro}$ module and is readily adaptable to $^{11}C$-labeling reactor for [$^{11}C$]PIB as well as another $^{11}C$-labeling apparatus for [$^{11}C$]methionine via the three-way valve. After completing the [$^{11}C$]PIB production, the re-synthesized $[^{11}C]CH_3I$ was passed through the three-way valve connected the polyetheretherketone (PEEK) line and loaded into the C18 Sep-Pak cartridge including the methionine precursor. The labeled product [^${11}C$]methionine was purified by a simple cartridge separation and reformulated into saline. The radiochemical yield of [$^{11}C$]PIB and [$^{11}C$]methionine were $5.3{\pm}0.6%$ and $18.7{\pm}0.8%$ (n.d.c.), respectively, with over 97% of radiochemical purity. The specific activity of [$^{11}C$]PIB was over $110GBq/{\mu}mol$. Total production time of two radiopharmaceuticals needs about 2 h from $1^{st}$ beam irradiation including quality control tests. Final [$^{11}C$]PIB and [$^{11}C$]methionine were satisfied all quality control test standards.

• The KIPS Transactions:PartD
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• v.12D no.7 s.103
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• pp.1049-1064
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• 2005

The demands of increasingly complicated software have led to the proliferation of object-oriented design methodologies in embedded systems. To execute a system designed with objects in target hardware, a task set should be derived from the objects, representing how many tasks reside in the system and which task processes which event arriving at an object. The derived task set greatly influences the responsiveness of the system. Nevertheless, it is very difficult to derive an optimal task set due to the discrepancy between objects and tasks. Therefore, the common method currently used by developers is to repetitively try various task sets. This paper proposes Scenario-based Implementation Synthesis Architecture (SISA) to solve this problem. SISA encompasses a method for deriving a task set from a system designed with objects as well as its supporting development tools and run-time system architecture. A system designed with SISA not only consists of the smallest possible number of tasks, but also guarantees that the response time for each event in the system is minimized. We have fully implemented SISA by extending the ResoRT development tool and applied it to an existing industrial PBX system. The experimental results show that maximum response times were reduced $30.3\%$ on average compared to when the task set was derived by the best known existing methods.

• The Korean Journal of Nuclear Medicine Technology
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• v.15 no.2
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• pp.72-75
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• 2011

Purpose: The HSV1-tk reporter gene system is the most widely used system because of its advantage is that it is possible to monitor directly without the introduction of a separate reporter gene in case of HSV1-tk suicide gene therapy. This study was performed to automate 9-(4-[$^{18}F$] Fluoro-3-hydroxymethylbutyl) guanine ([$^{18}F$] FHBG) that are widely used as substrate for the HSV1-tk reporter gene in living organisms with positron emission tomography (PET) and find the optimized conditions of synthesis. Materials and Methods: Fully automated synthesis of [$^{18}F$] FHBG was performed using Explora-RN (CTI, USA) module. We have changed of reaction time (3, 5, 10 min) and temperature (110, 120, $130^{\circ}C$) for the optimized conditions of synthesis. Also we experimented to find the optimal concentration of precursor (5, 7, 10 mg). Results: [$^{18}F$] FHBG was purified by HPLC system and collected at around 10-12 min. Synthesis using Explora-RN module showed a $32.0{\pm}1.2%$ yield of radiochemical (decay corrected), the purity was greater than 98%. And the entire synthesis time was less than 48 min. Temperature of the highest synthesis yield was $130^{\circ}C$, reaction time was 5 minutes and concentration of precursor was 10 mg (recommended volume in manual) (n=36). In contrast to radiochemical yield of precursor 10 mg ($32{\pm}1.2%$), yield of 5 and 7 mg precursor was unstable. Conclusion: Automation of [$^{18}F$] FHBG synthesis at Explora-RN module has been completed. In addition, we were able to obtain optimized reaction time, temperature and concentration of precursor. Therefore this study would be provided more rapid synthesis and higher radiochemical yield.

• Journal of Korean Society of Steel Construction
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• v.12 no.3 s.46
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• pp.329-337
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• 2000

The Load and Resistance Factor Design(LRFD) Specification defines two sets of limiting width-to-thickness ratios. On the basis of these limiting values, steel sections are subdivided into three categories: compact, noncompact, and slender sections. In this paper, I-Type girders of a 2 span continuous steel bridge are divided into compact and non-compact sections and analyzed. In the design process, an optimization formulation was adopted and ADS, a Fortran program for Automated Design Synthesis, was used. In this study, we studied about change of the section between compact and non-compact using optimization formulation.