• Transactions of the Korean Society of Mechanical Engineers A
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• v.20 no.7
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• pp.2108-2117
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• 1996

The purpose of this paper is to investigate the influence of the exciter attached for the measurement of natural frequencies when extracting the frequency response functions of the test structure in experimental modal analysis. The procedure is first to model the attached exciter as an additional degree of freedom system and next to verify the suggested model by experimentally extracting the natural frequencies of the test structure with various values of exciter mass, stinger stiffness and attachment position of the exciter on the test structure. It is concluded that as additional degree of freedom system which includes the natural frequency of the exciter itself and axial stiffness of stinger should be considered to quantatively define the coupling effects of structure-exciter interaction on the measured natural frequencies. It is not the mass of the exciter itself but the coupling effect of the additional degree of freedom mass-spring system consisting of exciter body and armature coil that characterizes the natural frequency deviation. Therefore, when the natural frequency of this additional mass-spring system is outside of the test frequency range, the coupling effect of structure-exciter interaction can be minimized.

• Biomolecules & Therapeutics
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• v.23 no.6
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• pp.493-509
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• 2015

Antibody-drug conjugates utilize the antibody as a delivery vehicle for highly potent cytotoxic molecules with specificity for tumor-associated antigens for cancer therapy. Critical parameters that govern successful antibody-drug conjugate development for clinical use include the selection of the tumor target antigen, the antibody against the target, the cytotoxic molecule, the linker bridging the cytotoxic molecule and the antibody, and the conjugation chemistry used for the attachment of the cytotoxic molecule to the antibody. Advancements in these core antibody-drug conjugate technology are reflected by recent approval of Adectris$^{(R)}$(anti-CD30-drug conjugate) and Kadcyla$^{(R)}$(anti-HER2 drug conjugate). The potential approval of an anti-CD22 conjugate and promising new clinical data for anti-CD19 and anti-CD33 conjugates are additional advancements. Enrichment of antibody-drug conjugates with newly developed potent cytotoxic molecules and linkers are also in the pipeline for various tumor targets. However, the complexity of antibody-drug conjugate components, conjugation methods, and off-target toxicities still pose challenges for the strategic design of antibody-drug conjugates to achieve their fullest therapeutic potential. This review will discuss the emergence of clinical antibody-drug conjugates, current trends in optimization strategies, and recent study results for antibody-drug conjugates that have incorporated the latest optimization strategies. Future challenges and perspectives toward making antibody-drug conjugates more amendable for broader disease indications are also discussed.

• Journal of the Korean Society of Clothing and Textiles
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• v.13 no.3 s.31
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• pp.252-258
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• 1989

The purpose of this study was to investigate the general Kasa. More specially, the objectives of the research was (a) to determine the reason why dyes the colour of kasa; (b) to examine the kinds of Kasa colour; (c) to provide the dyeing method of Kasa colour; (d) to clarify the prohibited colour and the permitted limit; and (e) to find which and why kasa colour in our country use. The reason why dyes the colour of Kasa are the following; (a) it differentiates between the white robe in the leading ascetic life of Buddhism at ones home and that of the entering the priesthood. (b) it protects the victim of robbery (c) it discards the attachment to the ownership (d) it lessens the burden of at alms. The kinds of Kasa's color consist of several one such as 증(cheung), 흑(heuk), 전(chun), 목란(mokran), and so on. The three colour among them use as the colour of kasa in the each vinaya pitaka. The dyeing method of kasa is composed of two ways; One is to dye the whole Kasa; the other is to dye the part of Kasa. Recently, in our country, the red which is the branch of kalasama is the leading colour of Kasa.

• Journal of Korean Society for Atmospheric Environment
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• v.19 no.1
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• pp.77-84
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• 2003

HS, Ammonia, CH$_4$, VOCs, Microorganism, Bacteria etc produced from swineries or henhouses are known to prevent the growth of livestock. Moreover, they give an unpleasant feeling to the workers. In this study, a methodology to remove odors and toxic gases by oxidation of ozone was thus accomplished. However, most ozone generators which use the atmospheric surrounding air have problems of contamination of electrode for discharge. Therefore in this work, a wire-cylinder type plasma reactor with DC voltage has been used both in a laboratory scale test and in the real swinery to solve the existing problems. About 6 cm of electrode gap could decrease the attachment of dusts, humid aerosols and other polymers, which are contained in the air. This compact designed device could produce ozone to oxidize and remove the air pollutants. But the amount of ozone was not large enough to be harmful to human Health. Also, the concentration of ozone was able to be varied by the input voltage. which makes it available for the proposed system to be installed in various kinds of pig houses. With this device, at maximum 43 mg/㎥ (20 ppm) of ozone could be produced at 40 ㎸ input voltage (consumed energy was 0.1 Wh/㎥). A program was also made in this work to calculate the optimum parameters for design of a plasma reactor in wide range of conditions.

• Proceedings of the Korean Society for Agricultural Machinery Conference
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• 1993.10a
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• pp.227-238
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• 1993

IRRI Engineering Division has developed a well drilling rig attachment that matched power tiller or hand tractor. It was designed in response to the growing demand for ground water utilization for small-scale irrigation, especially in drought-sticken and rained farms in Asian countries. The power tiller-driven rig can drill 30 meters of 100mm well in an unconsolidated formation in one day and can be rapidly converted from rotary to jetting or to the percussion method of drilling to suit different soil and rock formation. In addition, the power tiller can be quickly installed or removed from the rig frame and can be used for transporting the rig to other sites. The rig can be dismantled into smaller sub-assemblies for carrying by hand into less accessible areas. One manufacturer in Central luzon Philippines has started to produce the rig for well drillers in Central Luzon. The Department of Agriculture in the Philippines have procured thirty three(33) units of these machines f r their Shallow Tubewell program.

• Wind and Structures
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• v.2 no.4
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• pp.267-284
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• 1999

Multiple tuned mass dampers are proposed to suppress the vertical and torsional buffeting and to increase the aerodynamic stability of long-span bridges. Each damper has vertical and torsional frequencies, which are tuned to the corresponding frequencies of the structural modes to suppress the resonant effects. These proposed dampers maintain the advantage of traditional multiple mass dampers, but have the added capability of simultaneously controlling vertical and torsional buffeting responses. The aerodynamic coupling is incorporated into the formulations, allowing this model to effectively increase the critical speed of a bridge for either single-degree-of-freedom flutter or coupled flutter. The reduction of dynamic response and the increase of the critical speed through the attachment of the proposed dampers to the bridge are also discussed. Through a parametric analysis, the characteristics of the multiple tuned mass dampers are studied and the design parameters - including mass, damping, frequency bandwidth, and total number of dampers - are proposed. The results indicate that the proposed dampers effectively suppress the vertical and the torsional buffeting and increase the structural stability. Moreover, these tuned mass dampers, designed within the recommended parameters, are not only more effective but also more robust than a single TMD against wind-induced vibration.

• Women's Health Nursing
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• v.19 no.3
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• pp.129-141
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• 2013

Purpose: The purpose of this study was to determine the current state of nursing intervention for maternal adaptation and its' effectiveness in Korea by utilizing a systematic review. Methods: The PICO(Population-Intervention-Compar ator-Outcome) strategy was established, and 1,720 pieces of literature published during the last ten-year period from four electronic databases were reviewed. Eighteen references that met inclusion and exclusion criteria were finally selected for systematic review. The quality of references using critical appraisal checklist for experimental studies were evaluated, and then systematic review and meta-analysis were conducted. Results: All 18 references were quasi-experimental research design. Most interventions were provided at the hospital and postpartum care center. Maternal adaptation interventions appeared to be of many types, and particularly maternal role education programs were the most common. Confidence in maternal role was used as the most common variable for the maternal adaptati on. Various interventions for helping maternal adaptation in the postnatal period improved maternal confidence, moth er-infant attachment, maternal satisfaction and mother-infant interaction effectively. Conclusion: A diversity of nursin g interventions in postnatal period improved various aspects of maternal adaptation. Randomized controlled trials and longitudinal studies are needed in order to verify the effect of interventions for maternal adaptation more clearly.

• Asian Journal of Business Environment
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• v.7 no.3
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• pp.33-43
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• 2017

Purpose - It is necessary to identify the level of marketing activities of the businesses that are recognized and carried out by the small and midsize businesses that have been supported by the government's small-business policy Research design, data, and methodology - The method of data analysis of this study was conducted by the researcher's acquaintances and center staffs who visited small business owners in a small - scale company operating a business. Results - It is found that the financial support part of the support programs for the small business owners is not related to the center affection among the support programs for the small business owners of the government. This is a fact-finding process that can be regarded as a forming process that has a significant effect on. As a result of the analysis, both marketing activity and center attachment were found to be possible parameters which have significant influence on business performance. Conclusions - Developing a variety of contact and customer management programs with small business owners in the field has enabled the government's policies to effectively penetrate the site, and these efforts eventually resulted in more business results for small business owners.

• Journal of Distribution Science
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• v.14 no.8
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• pp.35-44
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• 2016

Purpose - This study aims to understand the relationship between Chinese local SNS usage and social capital building through Chinese international students in South Korea. A research model that illustrates the relationship between the SNS usage (i.e., intensity, communication and social capital building is proposed. Based on the analysis, this study will provide responses to the question of if SNS really presents the danger of trapping international consumers in their local comfort zone or enhance social capital for the users. Research design, data, and methodology - The survey questionnaire is circulated among the WeChat (a Chinese local SNS) users who are the Chinese international students studying in South Korea. The collected data is analyzed by structural equation method using SPSS and AMOS. Results - Proposed hypotheses of the positive relationships between the attachment of SNS use and both individuals' bridging and bonding social capital are supported. It's also supported that (1) interpersonal communication, (2) interpersonal communication with old friends, and (3) interpersonal communication for making new friends on SNS positively influence individuals' bridging social capital. Conclusions - This paper demonstrates the importance of intensity of WeChat use and interpersonal communication that impact Chinese international students' bridging and bonding social capital on WeChat.

• Journal of Sport and Applied Science
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• v.4 no.3
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• pp.11-22
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• 2020

Purpose: The purpose of this study is to analyze the effect of college sport club participants' ego-resilience on the college adjustment. Research design, data, and methodology: To accomplish the purpose, 360 participants were sampled by means stratified cluster random sampling method. Only 317 questionnaires were statistically processed, while 43 questionnaires were excluded because their respondents failed to complete instrument and judged insincere in filling out questionnaire. To analyze the data collected, statistical techniques, such as descriptive statistics, reliability analysis, independent-sample t-test, and one-way ANOVA, multiple regression analysis were used, and as for difference verification between individual groups in relation to significant results, Duncan's multiple range was conducted. Results: The following results have been drawn out via hypothesis test. First. the background variable of the college sport club participants of was proved to affect the degree of their ego-resilience on the college adjustment. Specifically, their period of participation, frequency of participation and expenses made a statistically meaningful. Second, the college sport club participants of ego-resilience were proved to affect the college adjustment. Academic adjustment, social adjustment, personal-emotional adjustment and institutional attachment made a statistically meaning-full difference. Conclusions: The findings indicate the function of sport club participants' ego-resilience in assisting their adjustment.