• Journal of Korean Public Health Nursing
• /
• v.37 no.1
• /
• pp.136-146
• /
• 2023

This cross-sectional design study was undertaken to determine the factors associated with suicidal ideation in human immunodeficiency virus (HIV)-infected older adults. Data from a city-wide representative sample collected by the Seoul Metropolitan Government were used. The cross-sectional survey was conducted between February and March 2013. Participants selected and included in the analysis were HIV-infected adults living in Seoul, and aged 50 years and older. The overall adjusted model showed that being unemployed (adjusted odds ratio [aOR], 3.34; 95% confidence interval [CI], 1.16-9.57), a history of depression treatment (aOR, 4.61; 95% CI, 1.02-20.66), perceived belongingness (aOR, 0.63; 95% CI, 0.41-0.99), and psychological functioning (aOR, 0.85; 95% CI, 0.73-0.99) were significantly related to suicidal ideation. Psychosocial features were found to be strongly associated with suicidal ideation among HIV-infected older adults. The findings could be useful for HIV nursing consultants to identify HIV-infected older adults who are vulnerable to suicidal ideation. Comprehensive mental health services should be provided as coping resources for HIV-infected older adults who have suicidal ideation.

• Anxiety and mood
• /
• v.16 no.2
• /
• pp.49-56
• /
• 2020

Objective : The present study aims to investigate differences in anger-related features in patients with somatic symptom disorder (SSD) compared to healthy controls, and to examine whether anger trait and anger regulation strategy are associated with clinical characteristics in patients with SSD. In addition, we examined the relationship between childhood adversity and SSD. Methods : 26 patients with SSD and 28 healthy controls were included. Anger-related features were assessed with State-Trait Anger Expression Inventory (STAXI). Clinical somatic symptoms were assessed using the somatization subscale of the Symptom Checklist-90-Revised and the Somatosensory Amplification Scale. Childhood adversity was assessed by the Childhood Traumatic Events Scale. Multivariate analysis of covariance was performed. Results : Disease status of SSD had a significant overall effect on anger-related features (Wilks λ=0.725, F(5, 44)=3.332, p=0.012). Patients with SSD showed a significantly high Trait-Anger (p=0.017) and they had a high score in both Anger-Out (p=0.013) and Anger-In (p=0.001) of anger expression styles. In particular, a directed inward style of anger expression was significantly associated with somatization symptom severity (p=0.003). Regarding childhood adversity, more childhood extreme illness was experienced by the SSD group than the control group (p=0.012). Within the SSD group, childhood extreme illness was associated with higher Trait-Anger (p=0.027) and Anger-Out (p=0.001). Conclusion : The present findings suggest that trait anger, anger expression styles, and childhood adversity of extreme illness may be involved in SSD. Further studies are needed to explore the role of anger-related features and its relationship with childhood adversity in the pathophysiology of SSD.

• Korean Journal of Radiology
• /
• v.22 no.11
• /
• pp.1786-1796
• /
• 2021

Objective: To evaluate the prognostic implications of preoperative magnetic resonance imaging (MRI) features of hepatocellular carcinoma (HCC) with a focus on those with targetoid appearance based on the Liver Imaging Reporting and Data System (LI-RADS), as well as known microvascular invasion (MVI) features. Materials and Methods: This retrospective study included 242 patients (190 male; mean age, 57.1 years) who underwent surgical resection of a single HCC (≤ 5 cm) as well as preoperative gadoxetic acid-enhanced MRI between January 2012 and March 2015. LI-RADS category was assigned, and the LR-M category was further classified into two groups according to rim arterial-phase hyperenhancement (APHE). The imaging features associated with MVI were also assessed. The overall survival (OS), recurrence-free survival (RFS), and their associated factors were evaluated. Results: Among the 242 HCCs, 190 (78.5%), 25 (10.3%), and 27 (11.2%) were classified as LR-4/5, LR-M with rim APHE, and LR-M without rim APHE, respectively. LR-M with rim APHE (vs. LR-4/5; hazard ratio [HR] for OS, 5.48 [p = 0.002]; HR for RFS, 2.09 [p = 0.042]) and tumor size (per cm increase; HR for OS, 6.04 [p = 0.009]; HR for RFS, 1.77 [p = 0.014]) but not MVI imaging features (p > 0.05) were independent factors associated with OS and RFS. Compared to the 5-year OS and RFS rates in the LR-4/5 group (93.9% and 66.8%, respectively), the LR-M with rim APHE group had significantly lower rates (68.0% and 45.8%, respectively, both p < 0.05), while the LR-M without rim APHE group did not significantly differ in the survival rates (91.3% and 80.2%, respectively, both p > 0.05). Conclusion: Further classification of LR-M according to the presence of rim APHE may help predict the postoperative prognosis of patients with a single HCC.

• Journal of Acupuncture Research
• /
• v.36 no.3
• /
• pp.131-139
• /
• 2019

Background: This study aimed to investigate the correlation between heat transmission and intervention factors for warm acupuncture (such as features of acupuncture material and moxa, the treatment method, and clinical symptoms). Methods: Korean, English, Chinese and Japanese databases were analysed. Experimental studies that explored the association between thermal stimulation delivery and warm acupuncture intervention factors were included. The peak temperature, time to reach the peak temperature, and time of the effective stimulus, were set as the major parameters and analysed. Results: A total of 12 studies were included. Two studies were associated with the acupuncture needle material, 4 studies associated with the moxa mass, 1 study associated with the moxa density, 2 studies associated with the location of ignition, and 1 study associated with treatment environment were reviewed. The reporting quality of the 12 studies was low. Conclusion: This study provided limited information because of the heterogeneity of materials and parameters depending on each experiment. Further studies should clarify the correlation between heat transmission and intervention factors for warm acupuncture.

• Journal of Interdisciplinary Genomics
• /
• v.2 no.2
• /
• pp.13-17
• /
• 2020

Infantile nystagmus syndrome (INS) is a genetically heterogeneous disorder. To date, more than 100 genes have been reported to cause INS and there is significant overlap in phenotypic characteristics. The most common form of X-linked INS is attributed to FRMD7 at Xq26. Recent advances in molecular genetics have facilitated the identification of pathogenic variants of FRMD7 and the investigation for underlying mechanisms of FRMD7-associated INS. This review summarizes genetic and clinical features of FRMD7-associated INS, and introduces updates on the pathogenesis of FRMD7 mutation.

• Journal of Genetic Medicine
• /
• v.1 no.1
• /
• pp.11-16
• /
• 1997

A nine month old male child presenting degenerating right ulna (massive osteolysis) has been followed up for two years. The bone completely disappeared due to abscesses on the right forearm and without orthopedic or haematological complications. Repeated lymphocyte cultures showed somatic pairing (mostly chromosome pair 5), end to end association involving chromosome 14, 21, 21 and 16, and satellite enlargement in a high proportion of cells with an otherwise normal 46,XY karyotype. These observations are compared with 13 other types of orthopaedic patients, and we opine that cumulative picture of chromosomal aberrations appears to correspond with the present rare anomaly "Mono Ostolic Osteolysis" involving right ulna. None of the controls or any other orthopaedic anomaly studied hereunder exhibits this chromosomal picture.

• Tuberculosis and Respiratory Diseases
• /
• v.84 no.4
• /
• pp.255-262
• /
• 2021

Microscopic polyangiitis (MPA) is an antineutrophil cytoplasmic antibody (ANCA)-associated necrotizing vasculitis, which mainly affects small vessels in various organs, especially the lungs. The two key pulmonary manifestations, interstitial lung disease (ILD) and diffuse alveolar hemorrhage (DAH), increase the morbidity and death rate of patients with MPA. ILD is more common in MPA than in other ANCA-associated vasculitis subsets and is primarily associated with myeloperoxidase-ANCA. Unlike alveolar hemorrhage due to pulmonary capillaritis, ILD can initially manifest as isolated pulmonary fibrosis. Of note, its most frequent radiographic pattern is the usual interstitial pneumonia pattern, similar to the characteristic pattern seen in idiopathic pulmonary fibrosis. In this review we present the pathogenesis, clinical manifestations, and radiographic and histopathologic features of ILD and DAH in MPA. We also briefly summarize the outcome and therapeutic options for the two conditions.

• Animal Systematics, Evolution and Diversity
• /
• v.40 no.3
• /
• pp.157-166
• /
• 2024

A new oenonid polychaete, Arabella turbidiricolor sp. nov., collected from intertidal zone along the coasts of eastern, western, and southern Korea is described. In Korea, this new species might have been confused with Arabella iricolor(Montagu, 1804), the type species of the genus, in having the following characteristics: ventralmost chaeta tapering gradually to guard, MI left robust and right gracile, MII right long, MV both with one tooth and posterior postchaetal lobe shorter than chaetae. However, A. turbidiricolor sp. nov. is readily distinguished from the latter by the following features: ventral maxillary carriers longer than or equal to dorsal, MI both distally falcate, and pygidium with two swollen pads. We provide detailed descriptions and illustrations for the new species in the present study. Also, morphological characteristics of known Arabella species are compared and discussed with a key to them.

• International Journal of Control, Automation, and Systems
• /
• v.3 no.4
• /
• pp.571-579
• /
• 2005

In this paper, we proposed an algorithm for arrhythmia classification, which is associated with the reduction of feature dimensions by linear discriminant analysis (LDA) and a support vector machine (SVM) based classifier. Seventeen original input features were extracted from preprocessed signals by wavelet transform, and attempts were then made to reduce these to 4 features, the linear combination of original features, by LDA. The performance of the SVM classifier with reduced features by LDA showed higher than with that by principal component analysis (PCA) and even with original features. For a cross-validation procedure, this SVM classifier was compared with Multilayer Perceptrons (MLP) and Fuzzy Inference System (FIS) classifiers. When all classifiers used the same reduced features, the overall performance of the SVM classifier was comprehensively superior to all others. Especially, the accuracy of discrimination of normal sinus rhythm (NSR), arterial premature contraction (APC), supraventricular tachycardia (SVT), premature ventricular contraction (PVC), ventricular tachycardia (VT) and ventricular fibrillation (VF) were $99.307\%,\;99.274\%,\;99.854\%,\;98.344\%,\;99.441\%\;and\;99.883\%$, respectively. And, even with smaller learning data, the SVM classifier offered better performance than the MLP classifier.

• Atmosphere
• /
• v.22 no.1
• /
• pp.29-45
• /
• 2012

An unusual autumn storm developed rapidly in the western part of the East sea on the early morning of 23 October 2006. This storm produced a record-breaking heavy rain and strong wind in the northern and middle part of the Yeong-dong region; 24-h rainfall of 304 mm over Gangneung and wind speed exceeding 63.7 m $s^{-1}$ over Sokcho. In this study, MTSAT-1R (Multi-fuctional Transport Satellite) water vapor and infrared channel imagery are examined to find out some features which are dynamically associated with the development of the storm. These features may be the precursor signals of the rapidly developing storm and can be employed for very short range forecast and nowcasting of severe storm. The satellite features are summarized: 1) MTSAT-1R Water Vapor imagery exhibited that distinct dark region develops over the Yellow sea at about 12 hours before the occurrence of maximum rainfall about 1100 KST on 23 October 2006. After then, it changes gradually into dry intrusion. This dark region in the water vapor image is closely related with the positive anomaly in 500 hPa Potential Vorticity field. 2) In the Infrared imagery, low stratus (brightness temperature: $0{\sim}5^{\circ}C$) develops from near Bo-Hai bay and Shanfung peninsula and then dissipates partially on the western coast of Korean peninsula. These features are found at 10~12 hours before the maximum rainfall occurrence, which are associated with the cold and warm advection in the lower troposphere. 3) The IR imagery reveals that two convective cloud cells (brightness temperature below $-50^{\circ}C$) merge each other and after merging it grows up rapidly over the western part of East sea at about 5 hours before the maximum rainfall occurrence. These features remind that there must be the upward flow in the upper troposphere and the low-layer convergence over the same region of East sea. The time of maximum growth of the convective cloud agrees well with the time of the maximum rainfall.