• Journal of Life Science
• /
• v.16 no.3 s.76
• /
• pp.409-414
• /
• 2006

Molecular chaperones and folding enzymes in the endoplasmic reticulum (ER) associate with the newly synthesized proteins to prevent their aggregation and help them fold and assemble correctly. Chaperone function of BiP, which is a Hsp70 homologue in ER, is controlled by the N-terminal ATPase domain. The ATPase activity of the ATPase domain is affected by regulatory factors. BAP was identified as a nucleotide exchange factor of BiP (Grp78), which exchanges ADP with ATP in the ATPase domain of BiP This study presents whether BAP can influence folding of a protein, immunoglobulin heavy chain that is bound to BiP tightly. We first examined which nucleotide of ADP and ATP affects on BAP binding to BiP The data showed that endogenous BAP of HEK293 cells prefers ADP for binding to BiP in vitro, suggesting that BAP first releases ADP from the ATPase domain in order to exchange with ATP. Immunoglobulin heavy chain, an unfolded protein substrate, was released from BiP in the presence of BAP but not in the presence of ERdj3, which is another regulatory factor for BiP accelerating the rate of ATP hydrolysis of BiP The ADP-releasing function of BAP was, therefore, believed to be responsible for immunoglobulin heavy chain release from BiP. Grp170, another Hsp70 homologue in ER, did not co-precipited with BAP from $[^{35}S]$-metabolic labeled HEK293 lysate containing both overexpressed Grp170 and BAP. These data suggested that BAP has no specificity to Grp170 although the ATPase domains of Grp170 and BiP are homologous each other.

• Journal of Life Science
• /
• v.27 no.7
• /
• pp.760-766
• /
• 2017

Genotypes of the nucleotide substitution g.23655332G>C of SNP marker rs385360448 at Lysophospholipase I (LYPLA1) gene intron 7, were tested for their effect on the carcass traits of Hanwoo and Jeju Crossbred cattle ($F_1$ progeny produced between Hanwoo ${\times}$ Jeju Black cattle) populations on Jeju Island. In the Hanwoo steer population, the meats containing LYPLA1 rs385360448 G/- genotypes showed significantly higher marbling scores and greater texture indices, compared to those of rs385360448 C/C homozygous animals (p<0.05). However, the LYPLA1 genotypes were not associated with the levels of carcass weight, backfat thickness, eye muscle area (EMA), meat color, and fat color (p>0.05). On the other hand, in the JCC steer population, the LYPLA1 G/- harboring meats showed significantly greater EMA levels, compared to those of C/C homozygotes (p<0.05). The results of the present study indicate that the LYPLA1 genotypes could alter the levels of intramuscular fat deposition, texture index, and eye muscle area via phospholipid metabolism in the Longissimus dorsi muscle of the cattle. These findings suggested that LYPLA1 genotypes may effect molecular genetic markers in the improvement of carcass traits of Hanwoo and Jeju Black industrial cattle populations on Jeju Island.

• Conservation Science in Museum
• /
• v.14
• /
• pp.23-28
• /
• 2013

This paper aimed to show the whole conservation process of the human shaped terra cotta mask that was excavated from one of construction sites at Jungcheon-ri, Geumsan-myeon, Jinju. This mask was X-rayed to get the correct making techniques and there are 4 holes on the top of the head and each diameter of the 3 holes is exact and the other hole is different from the three. The long and sharp shape of the nose is in trapezoid which was separately made with clay and put on (the face). It's found that there are round grooves each around upper and down lips. (upper in length: 10mm, down in length: 6 mm). All restoring materials and adhesives used for restoration to associate each piece are reversibility materials. According to a few points on buried bones of animals distributed around the sites, holes and grooves on the top of the head, ears and teeth to wear something, it academically presumes that this mask could be possibly used for the group ritual. Especially, the whole procedure from excavation to scientific conservation process resulted to have a special exhibition to give the public new eyes how the exhibition realizes to the public.

• Journal of the Korean Applied Science and Technology
• /
• v.37 no.5
• /
• pp.1208-1221
• /
• 2020

The purpose of this study was to provide basic data for predicting the sports consumption market that Generation Z will lead by applying data mining based decision tree analysis to explore Generation Z sports consumption style. Therefore, the survey was conducted by selecting males and females aged 19 or older as a sample among Generation Z, and data of 429 people were used for the final analysis. For data processing, frequency analysis, exploratory factor analysis, retest and reliability analysis, and decision tree analysis were performed using the SPSS statistics (ver. 21.0) program. The main results of this study are as follows. First, if the rational efficiency index is high and the aesthetic consumption index is low, the probability of being classified as a group of female was 96.8%. On the other hand, if the rational efficiency and perception of price index were low, the probability of being classified as a male group was 100%. Second, if the brand orientation, perception of price, and rational efficiency index were high, the probability of being classified as a capital area group was 97.3%. Contrary to the results presented above, the probability of being classified as a other area group was 82.1% when the brand orientation, commemoration rites, and status symbol index were low. Third, the status symbol and trend oriented index were high, and if the functionality index was low, the probability of being classified into daily life and fashion groups was 77.6%. On the contrary, if the status symbol index is low, the retention of membership and enjoy consumption index is high, the probability of being classified into exercise and competition groups was 81.0%.

• Korean Journal of Agricultural Science
• /
• v.3 no.1
• /
• pp.61-65
• /
• 1976

This study was conducted to induce superovulation by P.M.S. injection and P.M.S. associate with Estrogen comparatively in the rabbit. The results obtained in this study are as follows. At 23-48 hours following mating, there were 21.3-24.1 ova (Ovulation rate was increased 50.5-63.6%) in average in the group of 40 I.U P.M.S. injected per day per herd for 5 days (total 200 I.U. of P.M.S.) and 32.5-37.8 ova (Ovulation rate was increased 87.5-100%) in the group of P.M.S. associats with 0.1mg at 5th day. She number of unovulated-follicle were fewer in P.M.S.-Estrogen group than PMS group. As the result that dia meter of ova were classified in 3 group as 1-1. 4mm, 1.5-2.4mm and 2.5mm and observed, the ova in P.M.S. Estrogen group were slightly larger in size than P.M.S. group. It was conclued that P.M.S. associate with Estrogen injection was not so much effect on growth of ova but effect on ovulation of ova. so the number of ovulated ova were increased than P.M.S. group.

• Journal of dental hygiene science
• /
• v.11 no.6
• /
• pp.543-551
• /
• 2011

Critical thinking is recognized as core competency for dental hygiene practice. The purpose of this study was to investigate relationship between critical thinking disposition and grade, types of educational programs and satisfaction with interpersonal relationship, major, clinical practice. Total 909 students in associate and baccalaureate dental hygiene educational program completed self-reported questionnaire on critical thinking disposition inventory developed by Yoon(2004). The mean score for critical thinking disposition was 3.38~3.39 on a 5 point scale. There was no difference in critical thinking disposition scores between students of associate and baccalaureate programs. There was no difference in critical thinking disposition scores between grade of students. The results showed a statistically significant relationship between critical thinking disposition and satisfaction with interpersonal relationship and major. Multivariate analysis of variance(MANOVA) revealed that all subscales for three groups according to satisfaction with interpersonal relationship were significantly different(Pillai's trace=0.075, F(14,1782)=4.979, p<0.001) and all subscales for three groups according to satisfaction with major were significantly different(Pillai's trace=0.035, F(14,1728)=2.257, p=0.005).

• Asian-Australasian Journal of Animal Sciences
• /
• v.30 no.9
• /
• pp.1234-1238
• /
• 2017

Objective: The vertebral number is associated with body length and carcass traits, which represents an economically important trait in farm animals. The variation of vertebral number has been observed in a few mammalian species. However, the variation of vertebral number and quantitative trait loci in sheep breeds have not been well addressed. Methods: In our investigation, the information including gender, age, carcass weight, carcass length and the number of thoracic and lumbar vertebrae from 624 China Kazakh sheep was collected. The effect of vertebral number variation on carcass weight and carcass length was estimated by general linear model. Further, the polymorphic sites of Vertnin (VRTN) gene were identified by sequencing, and the association of the genotype and vertebral number variation was analyzed by the one-way analysis of variance model. Results: The variation of thoracolumbar vertebrae number in Kazakh sheep (18 to 20) was smaller than that in Texel sheep (17 to 21). The individuals with 19 thoracolumbar vertebrae (T13L6) were dominant in Kazakh sheep (79.2%). The association study showed that the numbers of thoracolumbar vertebrae were positively correlated with the carcass length and carcass weight, statistically significant with carcass length. To investigate the association of thoracolumbar vertebrae number with VRTN gene, we genotyped the VRTN gene. A total of 9 polymorphic sites were detected and only a single nucleotide polymorphism (SNP) (rs426367238) was suggested to associate with thoracic vertebral number statistically. Conclusion: The variation of thoracolumbar vertebrae number positively associated with the carcass length and carcass weight, especially with the carcass length. VRTN gene polymorphism of the SNP (rs426367238) with significant effect on thoracic vertebral number could be as a candidate marker to further evaluate its role in influence of thoracolumbar vertebral number.

• Journal of dental hygiene science
• /
• v.11 no.1
• /
• pp.7-14
• /
• 2011

This paper aims to comprehend the career plan and job view of the students of Dept. of Dental Hygiene who are expected to graduate with a bachelor of science degree, explain the characteristics of their jobs after graduation, compare them with the graduates of associate of science degree and finally give a basic data necessary for developing careers in the future. From the survey of 184 would-be graduates of Departments of Dental Hygiene at 6 universities that produce dental hygiene graduates in 2011 and 251 would-be graduates with a A.S. degree of Dept. of Dental Hygiene, whose course takes 3 years, this paper reaches the conclusion below. More graduates with B.S. degree in dental hygiene than those with a A.S. degree want to attend graduate school after graduation. It is found that most of the graduates with B.S. degree in dental hygiene wanted to work as a dental hygienist until they reach retirement age after getting a job. They favor dental hospitals, which give them a higher salary and ensure them of retirement age. They have a lower-esteemed job view: they think that their jobs are socially lower regarded, compared with graduates with a A.S. degree. It is found that those who wish to attend graduate school have lower job satisfaction than those who want to get a job after graduation. It is necessary for the educational institutes of dental hygiene to teach their graduates have a positive attitude their job and for the association to make an active effort to increase the job satisfaction of dental hygiene students as well as dental hygienists by enhancing social recognition of a dental hygiene.

• Journal of Biosystems Engineering
• /
• v.29 no.4
• /
• pp.341-346
• /
• 2004

Recent livestock people concern not only increase of production, but also superior quality of animal-breeding environment. So far, the optimization of the breeding and air environment has been focused on the production increase. In the very near future, the optimization will be emphasized on the environment for the animal welfare and health. Especially, cattle farming demands the precision livestock farming and special attention has to be given to the management of feeding, animal health and fertility. The management of individual animal is the first step for precision livestock farming and animal welfare, and recognizing each individual is important for that. Though electronic identification of a cattle such as RFID(Radio Frequency Identification) has many advantages, RFID implementations practically involve several problems such as the reading speed and distance. In that sense, computer vision might be more effective than RFID for the identification of an individual animal. The researches on the identification of cattle via image processing were mostly performed with the cows having black-white patterns of the Holstein. But, the native Korean and Japanese cattle do not have any definite pattern on the body. The purpose of this research is to identify the Japanese black cattle that does not have a body pattern using computer vision technology and neural network algorithm. Twelve heads of Japanese black cattle have been tested to verify the proposed scheme. The values of input parameters were specified and then computed using the face images of cattle. The images of cattle faces were trained using associate neural network algorithm, and the algorithm was verified by the face images that were transformed using brightness, distortion, and noise factors. As a result, there was difference due to transform ratio of the brightness, distortion, and noise. And, the proposed algorithm could identify 100% in the range from -3 to +3 degrees of the brightness, from -2 to +4 degrees of the distortion, and from 0% to 60% of the noise transformed images. It is concluded that our system can not be applied in real time recognition of the moving cows, but can be used for the cattle being at a standstill.

• Journal of radiological science and technology
• /
• v.5 no.1
• /
• pp.77-95
• /
• 1982

The result of this study from surveying and analyzing the present situation of educational institutes of radiologic technology, educational situation of radiologic technology, and students' attitude and recognition about the education of radiologic technology, the faculty's thought of it throughout the country from October, 1981 to April, 1982 is as follows: 1. The total number of educational institutes for radiologic technology is 11, but all of them are private colleges classified by foundation and 1,414 freshmen were admitted to enter the colleges by admission quotas of students at present in March, 1982. 2. The number of male(1965-1982) is 3,046(78.0%), that of female is 856(22.0%), and total of them is 3,904 that graduated from the departments of radiologic technology in 9 junior colleges in Korea. 3. The number of the instructional staffs in radiologic technology in Korea is 32, but among them 1 professor, 1 associate professor, 16 assistant professors and 14 full-time instructors. 4. The credits for graduation are 80-96 credits and students need required liberal arts and required major studies to get the qualification for graduation. 5. In the national examination for radio-technologist license, total 7,150 persons took the examination, but only 2,796 persons passed it, therefore, the average passed rate is 39.1% from the year 1965 to 1982. 6. 61.3% of students expressed dissatisfaction about their campus lives, the reason of which is mainly poor educational facilities(26.7%), insufficient number of faculty(21.2%) and negative Recognition on junior college from society, etc. 7. About the education of their major studies of colleges, 70.9% of students answered that they were short of laboratory works and clinical trainings rather than theoretical lessons. 8. The chief problem in practice works is about facilities and equipemtns for practice (students 39.1%, faculty 68.8%), and about the fact that too many students usually work at a time(students 17.1%, faculty 21.9%), etc. 9. 87.4% of students and 93.8% of faculty answered that clinical training in school is necessary. 10. Students' viewpoints on the radiologic technologist and the attitudes on the profession as a radiologic technologist are approximately affirmative. 11. Fields of employment to advance after graduation are mainly the fields related to their major studies(hospital, clinic, health clinic, industrial companies related and military officers of medical technology, etc.), which fields arc predominant to 74.5% rather than non-related fields(enrols into 4 year colleges, etc.). 12. 85.2% of students, 87.5% of the faculty expressed their opinions that the present academic years of 2 should be lengthened more. 13. 90.7% of the faculty expressed their opinions that the present students quotas should be reduced in whole or in part.