• Applied Microscopy
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• v.52
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• pp.11.1-11.9
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• 2022

Zoonotic poxvirus infections pose significant threat to human health as we have witnessed recent spread of monkeypox. Therefore, insights into molecular mechanism behind poxvirus replication cycle are needed for the development of efficient antiviral strategies. Virion assembly is one of the key steps that determine the fate of replicating poxviruses. However, in-depth understanding of poxvirus assembly is challenging due to the complex nature of multi-step morphogenesis and heterogeneous virion structures. Despite these challenges, decades of research have revealed virion morphologies at various maturation stages, critical protein components and interactions with host cell compartments. Transmission electron microscopy has been employed as an indispensable tool for the examination of virion morphology, and more recently for the structure determination of protein complexes. In this review, we describe some of the major findings in poxvirus morphogenesis and the contributions of continuously advancing electron microscopy techniques.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.21 no.6
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• pp.440-447
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• 2020

Masonry structures are used as bearing walls in small buildings, but they are generally considered non-bearing walls. They are used as partition walls that divide the interior spaces of the frame structures of buildings. In addition, wetting techniques that use mortar as an adhesive between blocks or bricks in construction are vulnerable to climatic conditions, especially cracks in mortar, which can cause conduction collapse of the walls in seismic loading. The purpose of this research was to propose a dry concrete block construction method that complements the weak axial shear stiffness and improves the weakness of the wet construction method as well as to investigate its structural behavior. In this study, the material properties of concrete blocks were examined, and the seismic performance of the proposed dry assembly structure was verified by structural behavior tests on horizontal cyclic loads. First, in these study results, concrete blocks can be applied to the dry block construction method instead of wet construction methods because they secure more than C-type blocks in KS regulations. Second, the structural performance of the wall against a horizontal cyclic load indicates that the resisting force of the assembly block wall is increased by increasing the horizontal length of the wall, forming several diagonal cracks. Finally, the proposed dry block wall structure requires a seismic performance assessment considering that the ratio of the shape of the wall by height and length is considered a major influence variable on the structural behavior under a horizontal load.

• Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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• 2007.11a
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• pp.12-22
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• 2007

This paper presents to predict the powertrain structure-borne noise which is primary resource of interior noise. As the first step, it is built up a hybrid powertrain model which is based on the real powertrain which is verified with static and dynamic properties. The methods for verifying are modal analysis and running vibration testing which are experimentally implemented. Based on the Hybrid powertrain component model, an initial predictive assembly model is simulated. As the second step, the characteristic transfer functions are measured that are dynamic stiffness of rubber mounts and vibro-acoustic transfer function based on the acoustic reciprocity. Several techniques utilizing special experimental devices have been proposed for this research. Finally, the structure-borne noise by powertrain will be predict and verify with dynamic simulation and experiment.

• The Journal of Korea Robotics Society
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• v.12 no.3
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• pp.263-269
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• 2017

Recently, soft robots using soft materials are presented. Thanks to soft materials, soft robots have flexible, highly-stretchable or adaptable features. However, due to the flexibility of soft material, it is hard for soft robots to control accurately or perform high force. To deal with these limitations, variable stiffness technology, which enables the stiffness control of structure, has been developed. In this research, a dual-stiffness structure that is actuated by the assembly of two flexible structures are presented. Each flexible structure consists of flexible film part and rigid parts placed at regular intervals. The flexibility of film between rigid parts allows each structure to move softly. On the other hand, by combining two structures rigid part of each part constrain the degrees of freedom of the other side part. And this causes the stiffness of whole structure to be increased. This paper will cover concepts, design, analysis and experiments of this structure.

• Journal of the Economic Geographical Society of Korea
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• v.7 no.2
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• pp.261-281
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• 2004

The location of auto industry in Jeon-buk is due to the strategies for secure a low-priced industrial site of the auto assembly companies, which attained to quantitative growth stage in the early part 1990's, and the regional balanced development policy by the location of leader enterprise of the government. As a consequence of the reversal development pattern that is located the auto parts firm after locating the auto assembly companies, the Jeon-buk auto industry has many structural vulnerability. First, because of the lack development of auto parts industries, the auto assembly companies located in Jeon-buk are dependent many auto parts at a external region. Second, most of auto parts firm belongs to the singular assembly company exclusively. And the majority of auto parts industries are the low value-added products that are necessary a simple labor power. Third, the agglomeration undeveloped of associated industries with automobile caused a low competitiveness of invitation a manufacturing company as against other provinces. For a regional economic development by the auto industry, it is necessary a flexible regional structure of production through an agglomeration of associated industries. The geographical proximity between an assembly company and a parts firms is an important locational factor with the induction of Just-in-Time production system and a modularization in the auto industry. And a modularization applies to more new factory than the existing factories. So that, Jeon-buk self-government has to create an amicable industrial environment, try to attract an auto parts enterprises and plan an agglomerated industrial complex that is able to supply a parts modulated to assembly company.

• Journal of the Computational Structural Engineering Institute of Korea
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• v.37 no.3
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• pp.173-178
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• 2024

This study presents a technique for assessing the dimensional quality of assembly parts in Prefabricated Steel Structures (PSS) using a stereo vision sensor. The stereo vision system captures images and point cloud data of the assembly area, followed by applying image processing algorithms such as fuzzy-based edge detection and Hough transform-based circular bolt hole detection to identify bolt hole locations. The 3D center positions of each bolt hole are determined by correlating 3D real-world position information from depth images with the extracted bolt hole positions. Principal Component Analysis (PCA) is then employed to calculate coordinate axes for precise measurement of distances between bolt holes, even when the sensor and structure orientations differ. Bolt holes are sorted based on their 2D positions, and the distances between sorted bolt holes are calculated to assess the assembly part's dimensional quality. Comparison with actual drawing data confirms measurement accuracy with an absolute error of 1mm and a relative error within 4% based on median criteria.

• Journal of the Korean Applied Science and Technology
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• v.37 no.6
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• pp.1597-1604
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• 2020

In this study, a synthesized poly(amino acid) self-assembly grafted with valine molecules was investigated on the skin activity of skin growth factors. The amphiphilic grafted poly(amino acid) derivatives were successfully synthesized by varying of degree of substitution(DS) and polymerization (DP) with valine molecules forming a β-sheet structure. Then, the pro-collagen biosynthesis of EGF(epidermal growth factor) was improved by 20%, and the inhibitory ability of tyrosinase activity was increased by 6.5 times by self-assembling of EGF with the poly(amino acid)s having β-sheet structures. This strategy of preparing protein self-assembly with poly(amino acid) derivatives will help improve the stability of protein growth factors and use it in medicals as well as cosmeceuticals through skin improvement.

• Wind and Structures
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• v.1 no.4
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• pp.317-336
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• 1998

In this paper the appraisal of a folding dome structure under the influence of wind loading is discussed. The foldable structure considered is constructed from an assembly of interconnected elements, together with a flexible membrane, all of which are initially store in a compact form and on deployment expand, like an umbrella, into a dome structure. Loading on the dome was obtained from a wind tunnel analysis of the pressure distribution over the roof of a 1:10 scale model of the structure. The critical loading obtained from the wind tunnel investigation was used, together with individual member and material tests, to form a series of numerical non-linear finite element models which were, in turn, used to investigate the forces within the structure. The numerical analysis was used to determine the critical wind loading that the structure can sustain, as well as providing a method by which to investigate the failure modes of the structure. In order to enhance the load carrying capacity of the dome it was found that both the strength and stiffness of the structural nodes needed to be enhanced and in addition, changes were necessary to substantially increase the stiffness of the individual member and caps.

• 제어로봇시스템학회:학술대회논문집
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• 2003.10a
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• pp.2524-2528
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• 2003

High-precision position system is widely used in lots of fields such as semiconductor industry, biotechnology, display and other up-to-date industry field. One of the main issues is to have a long traveling range with precision. There are a few solutions. For instance, there are inchworm methods, lever principle. In this study, we use lever principle to amplify output displacement with a new mechanical amplification structure. We designed new type 3DOF stage with PZT actuator and capacitive sensor. Non-monolithic structure is suggested to obtain the convenience of assembly and modification. Driving parts are designed as modules that generate displacement amplification of each axis. Designed motion module consists of 3 flexure hinges and a PZT actuator with double L lever structure.

• Proceedings of the Korean Society of Machine Tool Engineers Conference
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• 2004.04a
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• pp.410-415
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• 2004

Heavy-weight head slides may cause excessive inertia impact ＆ moment on the machine tool structure when they move or stop abruptly during operation. Consequently these inertia impact and unbalanced moment bring transient vibrations and rough sliding motions on the machine structure. Machine tool engineers have tried many kind of feed-slide designs in order to solve this problem; for example, the design optimization of the moving structure for minimum weight and maximum stiffness, box-in-box type slide design, and so on. In this article, force and moment equilibrium equations regarding to the inertia force ＆ moment were derived for each one of a mold M/C's head slides. Furthermore, five different design configurations of head slide assembly were reviewed for its design improvement regarding to force ＆ moment calculations and finite element structural analysis results.