• Title/Summary/Keyword: Assembly Building

Search Result 233, Processing Time 0.025 seconds

Engineering Hybrid Proteins by Modular Recombination and Evolutionary Optimization (모듈성 단백질의 재설계 및 개량)

  • Lee, Seung-Goo;Rha, Eu-Gene;Ha, Jae-Seok;Lee, Jeong-Min;Kim, Sun-Hwa
    • Microbiology and Biotechnology Letters
    • /
    • v.36 no.2
    • /
    • pp.149-157
    • /
    • 2008
  • Many proteins consist of distinctive domains that can act independently or cooperatively to achieve a unique function. As these domains evolve from a naturally existing repertoire of functional domains, this implies that domain organization is an intrinsic element involved in building the complex structure and function of proteins. Thus, identifying functional domains would appear to be critical to the elucidation of questions related to protein evolution, folding, and the engineering of hybrid proteins for tai- lored applications. However, the simple application of "Lego-like assembly" to the engineering of hybrid proteins is an oversimplification, as many hybrid constructs lack structural stability, usually due to unfavorable domain contacts. Thus, directed evolution, along with computational studies, may help to engineer hybrid proteins with improved physico-chemical properties. Accordingly, this paper introduces several approaches to functional hybrid protein engineering that potentially can be used to create modulators of gene transcription and cell signaling, and novel biosensors to analyze biological functions in vivo.

The Use of Demand Controlled Ventilation in Multi-Purposed Facility (수요기반 환기량 조절법 (DCV)의 다중이용시설 적용방안)

  • Jeong, Jae-Weon;No, Sang-Tae
    • 한국태양에너지학회:학술대회논문집
    • /
    • 2008.04a
    • /
    • pp.111-116
    • /
    • 2008
  • The objective of this paper was to show the possibility of demand-controlled ventilation (DCV) using the current Korean ventilation standard for multi-purposed facilites. Two attractive DCV approaches; $CO_2$-DCV and RFID-DCV were applied to DCV simulations for a theoretical public assembly space served by a dedicated outdoor air system (DOAS) with enthalpy recovery device. A numerical model for predicting realtime occupant number, ventilation rate, and $CO_2$ concentration under given conditions was developed using a commercial equation solver program. It was found that the current ventilation standard causes unstable ventilation system control in DCV applications, especially under $CO_2$-DCV. It is because the ventilation rate (per person) used in Korea is the sum of the outdoor air required to remove or dilute air contaminants generated by both occupant and building itself, and not a pure function of occupant numbers. Finally, it makes DCV control unstable when ventilation flow is regulated only by the number of occupants. In order for solving this problem, current Korean ventilation standard was modified as a form of ASHRAE Standard 62.1-2007 showing good applicability to various DCV approaches. It was found that this modification enhances applicability of the current ventilation standard to DCV significantly.

  • PDF

KSLV-I 소형위성발사체 발사장 시스템설계(Ⅰ)

  • Lee, Young-Ho;Jin, Seung-Bo;Seo, Jin-Ho;Hong, Il-Hee;Cho, Gwang-Rae
    • Aerospace Engineering and Technology
    • /
    • v.3 no.2
    • /
    • pp.98-103
    • /
    • 2004
  • This paper describes a system design of Launch Ground Complex for the Korea Space Launch Vehicle-I which will play so important roles of successful execution for Korea National Space Development Program. Launch Ground Complex has to supply safe work space, construction and equipments for assembling, check-out and launching of the space launch vehicle, and it consists of Mechanical, Electrical, Fluid Ground Support Equipment and Infrastructure. Mechanical Ground Support Equipment consists of Launch Pad, Mobile Assembly Tower, Umbilical Tower, Lightning Tower, Theodolite Building and Auxiliary.

  • PDF

Experimental study of rigid beam-to-box column connections with types of internal/external stiffeners

  • Rezaifar, Omid;Nazari, Mohammad;Gholhaki, Majid
    • Steel and Composite Structures
    • /
    • v.25 no.5
    • /
    • pp.535-544
    • /
    • 2017
  • Box sections are symmetrical sections and they have high moment of inertia in both directions, therefore they are good members in tall building structures. For the rigid connection in structures with box column continuity plates are used on level of beam flanges in column. Assembly of the continuity plates is a difficult and unreliable work due to lack of weld or high welding and cutting in the fourth side of column in panel zone, so the use of experimental stiffeners have been considered by researchers. This paper presented an experimental investigation on connection in box columns. The proposed connection has been investigated in four cases which contain connection without internal and external stiffeners(C-0-00), connection with continuity plates(C-I-CP), connection with external vase shape stiffener (C-E-VP) and connection with surrounding plates(C-E-SP). The results show that the connections with vase plates and surrounding plates can respectively increase the ultimate strength of the connection up to 366% and 518% than the connection without stiffeners, in case connection with the continuity plates this parameter increases about 39%. In addition, the proposed C-E-VP and C-E-SP connection provide a rigid and safe connection to acquire rigidity of 95% and 98% respectively. But C-I-CP connection is classified as semi-rigid connections.

Study of Furniture Design Utilizing 3D Printers Joris Laarman (요리스 라만(Joris Laarman)의 3D프린터를 활용한 가구디자인에 관한 연구)

  • Lee, Hyun Jung
    • Journal of the Korea Furniture Society
    • /
    • v.27 no.2
    • /
    • pp.128-136
    • /
    • 2016
  • Digital designs that appear in the three-dimensional virtual space by the digital type are designed as there is not an image created with an organic artificially generated (Creation) and representation (Modifying), developed by the specific environment given. The advanced digital design will produce a result with an algorithm according to a mathematical operation and the environment and has the nature of generating the real world, changes, development and affinity (Genetic Process). The digital design process is largely defined by a set of processes that are consistently designed to integrate form of creation, reproduction, proceeds in three steps, while the manufacture and assembly as a form of maintenance as possible the intended form of control data from the concept of building. By Joris Laarman 3D printer design is a simulation created by the digital process by the various algorithms and design achieved through the development of 3D printers, such as new materials and MX3D. From the mold production of a complex whole by using a robot and other digital production tool extracts a variety of forms.

Architectural Acoustics Design of multipurpose Auditorium in S-high school (S고등학교(高等學校) 다목적(多目的) 강당(講堂)의 건축음향설계(建築音響設計))

  • Ju, Duck-Hoon;Yun, Jae-Hyun;Kim, Jae-Soo
    • Proceeding of Spring/Autumn Annual Conference of KHA
    • /
    • 2008.04a
    • /
    • pp.436-440
    • /
    • 2008
  • Among those various facilities attached to the school building, the Auditorium is being utilized for not only the Exercise Activity but also for many purposes such as Culture, Public Performance, Education, Assembly and so on. In order to utilize in maximum such function of the multipurpose auditorium, an adequate acoustic design with regard to the Clarity of Voice and Music in accordance with its use-purpose should be accompanied. However, as the most part of multipurpose auditoriums is designed with high ceiling-height by its peculiar character, and due to use of the material of strong reflexibility, it is appearing the defect that excessively exposes the reverberation of sound. In order to make out an optimal acoustic condition within the broad space such as an auditorium, the acoustic characteristics must be considered from the planning stage, however in the most case, those acoustic problems are being settled through the repair works after construction. On such viewpoint, this Study intends to analyze the room acoustic characteristics from the planning stage using a computer simulation based on the blueprint of multipurpose auditorium in S High School located in Gwangju. It is considered that the material analyzed in such way could be practically applied as a fundamental material enables to improve the acoustic capability when a similar broad space is planned hereafter.

  • PDF

Development of BIM Based Information Model Interface Module for a Modular Pier (모듈러 교각의 BIM 기반 정보 모델 인터페이스 모듈 개발)

  • Kim, Dong-Wook;Lee, Kwang-Myong;Nam, Sang-Hyeok
    • Journal of KIBIM
    • /
    • v.5 no.1
    • /
    • pp.1-7
    • /
    • 2015
  • Modular technology has become a major issue of the construction industries to enhance their productivity. Modular bridge construction generally requires the data exchange between the contractors, designers, fabricators and constructors. Therefore, a readily accessible information model interface module based on BIM technology is essential for their communication during a project life-cycle. In this study, BIM based information model interface module for a modular pier was developed. For the information models, the PBS(Product Breakdown Structure) and LOD(Level of Development) were defined. Next, all components of a modular pier were conducted by the parametric modeling technique, and then 3D cell library interface was developed. An nterface module was also developed using VBA(Visua basic Application) for exchanging a data from 3D model library to other softwares such as Microstation, AutoCad and Excel and was connected with MS Access database. The developed information model interface module would improve the design quality of the modular pier and reduce the time and cost for design. Updated 3D information models could be utilized for the fabrication, assembly, and construction process for modular piers.

Formation Rate of DNA Nanowires According to the APTES Concentration

  • Kim, Taek-Woon;Kim, Nam-Hoon;Roh, Yong-Han
    • Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
    • /
    • 2008.06a
    • /
    • pp.143-143
    • /
    • 2008
  • Nanowires are promising options for building nanoscale electronic structures coming from high conductivity of nanowires. In particular, Deoxyribonucleic acid (DNA), which is structurally nanowire, can obtain highly ordered electronic components for nanocircuitry and/or nanodevices because of its very flexible length controllability, nanometer-size diameter, about 2 nm, and self-assembling properties. In this work, we used the method to form DNA-Nanowires (NWs) by using chemical treatment on Silicon (Si) surface, and Aminopropyl-triethoxysilane (APTES) was used as inducer of DNA sequence to modify the characteristics of Si surface. Moreover, we performed tilting technique to align DNA by the direction of flow of DNA solution. We investigated the assembly process between DNA molecules and APTES - coated Si surface according to the APTES concentration, from $1.2{\mu}\ell$ to $120{\mu}\ell$. Atomic Force Microscopy (AFM) images showed the combination rate of DNA molecules by the change of APTES concentration. As APTES concentration becomes thicker, aggregation of DNA molecules occurs, and this makes a kind of DNA networks. In this respect, we confirmed that there's a positive relationship between the concentration of APTES and the formation rate of DNA nanowires. Since there have been lots of research preceded to utilize DNA nanowires as template, so by using this positive relationship with proper alignment technique, realization of nano electronic devices with DNA nanowires might be feasible.

  • PDF

Quick Fabrication of Three Dimensional Colloidal Crystals and Their Applications (3차원 콜로이드 광결정의 고속 제작 및 응용)

  • Lee, Su Jin;Im, Sang Hyuk
    • Korean Chemical Engineering Research
    • /
    • v.51 no.5
    • /
    • pp.640-643
    • /
    • 2013
  • On evaporation of water in polystyrene colloidal emulsion, the polystyrene colloidal particles are instantly protruded on the surface of water and are self-assembled by capillary force among the protruded particles. At the same time, the assembly of polystyrene colloidal particles is occurred on the surface of water owing to its lower effective density than water. Here we devised that the three-dimensional polystyrene colloidal crystals are quickly transferred onto the glass substrate by constructing wettable confined geometry on the glass substrate. We also applied the three-dimensional colloidal crystals to optical filters reflecting certain wavelength of light selectively by tuning the size of building blocks and incident angle of light.

The Result in Quality Management Activity of Propellant and Compressed Gases during the Operation of KSLV-I (KSLV-I 운용에서의 추진제 및 고압가스 품질관리 활동 결과)

  • Jung, Young-Suk;Kang, Sun-Il;Oh, Seung-Hyub;Chung, Eui-Seung
    • Aerospace Engineering and Technology
    • /
    • v.10 no.2
    • /
    • pp.133-145
    • /
    • 2011
  • This paper is about the results in Qualification Management activity performed between the Autonomous Test(AT) season(August. 2008) of Launch Complex and the 2nd flight test season(June. 10, 2010) of KSLV-I. All cryogenic fluids(LOX, $LN_2$) and compressed gases(Air, $GN_2$, GHe) were qualified by qualification management activity during AT(Autonmous Test), QT(Qualification Test) season for LP(Launch Pad) and LVAB(Launch Vehicle Assembly Building) and FT(Flight Test) season of KLSV-I. As the results, total 428 times of check analysis and 111 times of full analysis were performed.