• Asian Pacific Journal of Cancer Prevention
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• 제16권7호
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• pp.2857-2870
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• 2015

Although the incidence of breast cancer in Asia remains lower than in North America, Western Europe, and Oceania, rates have been increasing rapidly during the past few decades, and Asian countries now account for 40% of breast cancer cases diagnosed worldwide. Breast cancer mortality has also increased among Asian women, in contrast to decreased mortality in Northern America, Western Europe, and Oceania. These increased rates are associated with higher prevalence of breast cancer risk factors (e.g., reduced parity, delayed childbirth, increased obesity) that have accompanied economic development throughout the region. However, Asian regions (western, south-central, south-eastern, and eastern) and countries differ in the types and magnitude of changes in breast cancer risk factors, and cannot be viewed as a single homogeneous group. The objective of this paper was to contrast the heterogeneous epidemiology of breast cancer by Asian regions and countries, and to suggest potential avenues for future research.

• Journal of Preventive Medicine and Public Health
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• 제56권5호
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• pp.440-448
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• 2023

Objectives: The purpose of this study was to assess predictors of health-related quality of life (HRQoL) in elderly Asian American and non-Hispanic White cancer survivors. Methods: We conducted cross-sectional secondary data analyses using the combined datasets from the Surveillance, Epidemiology, and End Results program and the Medicare Health Outcomes Survey. Results: Elderly Asian American cancer survivors reported a lower mental HRQoL but a comparable physical HRQoL relative to elderly non-Hispanic White cancer survivors. Stress factors, such as comorbidities, difficulties with activities of daily living, and a history of depressive symptoms, along with coping resources like self-rated health and the ability to take the survey in English, were significantly associated with mental and physical HRQoL. Among elderly Asian American cancer survivors, a significantly lower mental HRQoL was observed among those taking the survey in the Chinese language. Conclusions: The findings suggest that race exerts a differential impact on HRQoL. Interventions should be designed to address the distinct cultural, linguistic, and systemic needs of elderly Asian American cancer survivors. Such an approach could assist in reducing cancer-related health disparities.

• 한국임상수의학회지
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• 제26권4호
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• pp.391-394
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• 2009

왼쪽 앞다리에 교상을 입은 아시아 물왕도마뱀은 세균감염에 의해 피부 출혈, 농포, 수포, 복부팽만, 패혈증의 증상을 보인 후 폐사하였다. 신장에서 균을 분리, 생화학적 검사와 PCR 방법을 이용 모가넬라 모가니로 동정하였다. 25종의 항생제 감수성 검사를 실시하였고 분리된 균을 1.6 ${\times}$ $10^{11}$CFU/mouse 농도로 마우스 복강에 접종, 포유류에 대한 병원성을 검사하였다. 실험결과 마우스는 모두 폐사하였다.

• Asian Pacific Journal of Cancer Prevention
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• 제15권10호
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• pp.4193-4196
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• 2014

Lingzhi or Ganoderma lucidum is a popular medicinal mushroom used as a health promotion herb in China and other Asian countries for thousands of years. There have many previous studies about the anti-cancer effects of lingzhi especially in vitro. The present study reports the clinical data of 5 gynecologic cancer patients who achieved stability in the disease after ingestion of lingzhi in the form of fruit body water extract and spores in a salvage setting. This report has been written to enhance the data describing the effect of lingzhi in cancer patients.

• 대한한의학원전학회지
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• 제35권1호
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• pp.93-102
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• 2022

Objectives : We propose a method for constructing a thesaurus of Traditional East Asian Medicine terminology using machine learning. Methods : We presented a method of combining the 'Automatic Step' which uses machine learning and the 'Manual Step' which is the operator's review process. By applying this method to the sample data, we constructed a simple thesaurus and examined the results. Results : Out of the 17,874 sample data, a thesaurus was constructed targeting 749 terminologies. 200 candidate groups were derived in the automatic step, from which 79 synonym groups were derived in the manual step. Conclusions : The proposed method in this study will likely save resources required in constructing a thesaurus.

• 대한한의학원전학회지
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• 제36권2호
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• pp.23-34
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• 2023

Objectives : We propose a method to disassemble Traditional East Asian Medicine herbal formulas using machine learning. Methods : After creating a model using Byte Pair Encoding(BPE) and G-Score, the model was trained with training data. Afterwards, the learned model was applied to the test data, of which the results were compared with expert opinion. Results : The results acquired through the model were not significantly different from those of modern expert opinions. However, there were cases where the meaning was partially unclear, while there were cases where new knowledge could be obtained through the disassembling process. Conclusions : It is expected that disassembling herbal formulas through the proposed method in this study will help save resources required to understand complex ones.

• Asian-Australasian Journal of Animal Sciences
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• 제11권3호
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• pp.318-322
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• 1998

Using polyacrylamide-gel isoelectric focusing followed by immunoblotting, genetic polymorphism of plasma vitamin D-binding protein (Gc) was examined in Asian sheep. The Gc polymorphism was revealed in the Khalkhas sheep of Mongolia, consisting of F, S and W variants, and the Yunnan native sheep of China, consisting of F and S variants. In particular, W was a new variant. The V variant detected in European sheep up to now was not observed in these sheep. The Bhyanglung, Baruwal, Kagi and Lampuchhre sheep of Nepal and local sheep of Bangladesh and Vietnam were monomorphic for the S variant. Family data and population genetic data supported the hypothesis that these variants were controlled by codominant alleles. In these Asian sheep, distribution of the $Gc^s$ allele was predominant (0.9571-1) and was seen as well in European sheep (Suffolk, Corriedale, Cheviot and Finnish Landrace) raised in Japan. $Gc^w$ allele was detected only in the Khalkhas sheep with the low frequency of 0.0025. The $Gc^v$ allele was detected in the Suffolk and Corriedale sheep (0.0080 and 0.0682), but not in any of the Asian sheep studied.

• 대한의생명과학회지
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• 제20권3호
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• pp.173-179
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• 2014

Asian sand dust is known to promote various respiratory symptoms or disorders. For the prevention of harmful health effects by Asian sand dust, the best strategy is known to avoid or reduce exposure to the Asian sand dust. Several studies have shown that Korean red ginseng (RG) has anti-inflammatory and anti-allergic effects. The study aimed to clarify the effect of Korean red ginseng intake on lung inflammation responses to artificial sand dust (ASD) similar to Asian sand dust. BALB/c mice were divided into five groups (n=12) of control (saline), ovalbumin (OVA), OVA with ASD, OVA plus RG with ASD, and OVA plus dexamethasone (DEXA) with ASD. Histopathologic evaluation of lung was conducted. Interleukin (IL)-5, IL-12, interferon (IFN)-${\gamma}$, IL-13, monocyte chemotactic protein (MCP)-1, and eotaxin within bronchoalveolar lavage (BAL) fluid were measured by ELISA. OVA+ASD group significantly increased concentrations of IL-5, IL-13, MCP-1, and eotaxin (P<0.01) compared to the control. OVA+ASD+RG group showed significant decreased levels of IL-2, IL-13, MCP-1 and eotaxin (P<0.01) compared with OVA+ASD. Between RG and DEXA treatment groups, there was no significant difference in all cytokines and chemokines. The inflammatory cells were significantly decreased in treatment groups with RG or DEXA compared to OVA+ASD group. This study suggests a beneficial effect of Korean RG administration in preventing inflammation of lung resulting from Asian sand dust.

• 대한한의학원전학회지
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• 제33권2호
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• pp.51-59
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• 2020

Objectives : We would like to study what is the most appropriate "feature" to effectively perform authorship attribution of the text of Traditional East Asian Medicine Methods : The authorship attribution performance of the Support Vector Machine (SVM) was compared by cross validation, depending on whether the function words or content words, single word or collocations, and IDF weights were applied or not, using 'Variorum of the Nanjing' as an experimental Corpus. Results : When using the combination of 'function words/uni-bigram/TF', the performance was best with accuracy of 0.732, and the combination of 'content words/unigram/TFIDF' showed the lowest accuracy of 0.351. Conclusions : This shows the following facts from the authorship attribution of the text of East Asian traditional medicine. First, function words play an important role in comparison to content words. Second, collocations was relatively important in content words, but single words have more important meanings in function words. Third, unlike general text analysis, IDF weighting resulted in worse performance.

• Journal of Neurogastroenterology and Motility
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• 제25권3호
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• pp.343-362
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• 2019

Background/Aims There has been major progress in our understanding of the irritable bowel syndrome (IBS), and novel treatment classes have emerged. The Rome IV guidelines were published in 2016 and together with the growing body of Asian data on IBS, we felt it is timely to update the Asian IBS Consensus. Methods Key opinion leaders from Asian countries were organized into 4 teams to review 4 themes: symptoms and epidemiology, pathophysiology, diagnosis and investigations, and lifestyle modifications and treatments. The consensus development process was carried out by using a modified Delphi method. Results Thirty-seven statements were developed. Asian data substantiate the current global viewpoint that IBS is a disorder of gut-brain interaction. Socio-cultural and environmental factors in Asia appear to influence the greater overlap between IBS and upper gastrointestinal symptoms. New classes of treatments comprising low fermentable oligo-, di-, monosacharides, and polyols diet, probiotics, non-absorbable antibiotics, and secretagogues have good evidence base for their efficacy. Conclusions Our consensus is that all patients with functional gastrointestinal disorders should be evaluated comprehensively with a view to holistic management. Physicians should be encouraged to take a positive attitude to the treatment outcomes for IBS patients.