Journal of Veterinary Clinics (한국임상수의학회지)

The Korean Society of Veterinary Clinics (한국임상수의학회)
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Isolation and Characterization of Morganella morganii from Asian Water Monitor Varanus salvator

아시아 물왕도마뱀에서 분리된 모가넬라 모가니의 분리동정

  • Shin, Sang-Phil (Laboratory of Aquatic Animal Medicine and BK21 Program for Veterinary Science, College of Veterinary Medicine, Seoul National University) ;
  • Kim, Ji-Hyung (Laboratory of Aquatic Animal Medicine and BK21 Program for Veterinary Science, College of Veterinary Medicine, Seoul National University) ;
  • Gomez, Dennis K. (Laboratory of Aquatic Animal Medicine and BK21 Program for Veterinary Science, College of Veterinary Medicine, Seoul National University) ;
  • Choresca Jr., Casiano H. (Laboratory of Aquatic Animal Medicine and BK21 Program for Veterinary Science, College of Veterinary Medicine, Seoul National University) ;
  • Han, Jee-Eun (Laboratory of Aquatic Animal Medicine and BK21 Program for Veterinary Science, College of Veterinary Medicine, Seoul National University) ;
  • Park, Se-Chang (Laboratory of Aquatic Animal Medicine and BK21 Program for Veterinary Science, College of Veterinary Medicine, Seoul National University)
  • 신상필 (서울대학교 수의과대학 수생동물질병학연구실) ;
  • 김지형 (서울대학교 수의과대학 수생동물질병학연구실) ;
  • 데니스 고메즈 (서울대학교 수의과대학 수생동물질병학연구실) ;
  • 카시아노 추레스카 (서울대학교 수의과대학 수생동물질병학연구실) ;
  • 한지은 (서울대학교 수의과대학 수생동물질병학연구실) ;
  • 박세창 (서울대학교 수의과대학 수생동물질병학연구실)
  • Published : 2009.08.31
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Abstract

An Asian water monitor Varanus salvator with physical wound due to bite which was subsequently infected with bacterium resulting to hemorrhage and pus in the skin blisters, abdominal distention and septicemia. Morganella morganii was isolated and identified from the blood and kidney of the reptile, and confirmed by PCR and biochemical tests. The sensitivity of isolated strains to different groups of antibiotics was also evaluated using the disc diffusion method. Pathogenicity test using M. morganii (SNUFPC-MM01) (1.6 ${\times}$ $10^{11}$CFU/mouse) to suckling and adult mice resulted to the death of all mice. This paper describes the first isolation of M. morganii from Asian water monitor in Korea.

왼쪽 앞다리에 교상을 입은 아시아 물왕도마뱀은 세균감염에 의해 피부 출혈, 농포, 수포, 복부팽만, 패혈증의 증상을 보인 후 폐사하였다. 신장에서 균을 분리, 생화학적 검사와 PCR 방법을 이용 모가넬라 모가니로 동정하였다. 25종의 항생제 감수성 검사를 실시하였고 분리된 균을 1.6 ${\times}$ $10^{11}$CFU/mouse 농도로 마우스 복강에 접종, 포유류에 대한 병원성을 검사하였다. 실험결과 마우스는 모두 폐사하였다.

Keywords

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