• The Journal of Dong Guk Oriental Medicine
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• v.8 no.1
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• pp.159-169
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• 1999

Osteomalacia is syndrome of diverse etiology. characterized pathophysiologically by a failure of normal mineralization of bone and epiphyseal cartilage. This study was performed to investigate causes of disease, pathogenic mechanisms, symptoms, therapies and precriptions through the successive medical literatures. recent chinese medical literatures and chinese medical journals. It is similar to atrophic debility of bones, bone leaning, bone exhaustion, rheumatism involving the bone, osteodynia and cold and heat of bone etc. of oriental medicine. The most principal cause of this is deficiency of kidney. similar to hypophosphatemia caused by increased renal clearance and deficiency of vitamin D, and the rest are senility, deficiency of spleen, deficiency of qi and deficiency of blood. There are nourishing the kidney and spleen, nourishing the qi and blood, warming and passing the muscle and mac, passing an articulation an invigorating the muscle and bone, in principal therapy. And in medical herbs are rehmanniae radix preparat, corni fructus, discoreae rhizoma, cuscutae semen, tigridis os, juglandis semen, hominis placenta, drynariae rhizoma, eucommiae cortex, cynomorii herba, cervi cornus colla, cervi pantotrichum cornu, moutan cortex, polygoni multiflori radix, angelicae gigantis radix, achyranthis bidentatae radix, cibotii rhizoma, hirudo, eupolyphaga, spatholobi caulis, salviae miltiorrhizae radix, draconis resina, curcumae longae rhizoma. In care there are a sun-bath, exercise, high protein diet and taking vitamin D. And they reduce smoking, coffee, drinking etc.

• Phonetics and Speech Sciences
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• v.12 no.2
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• pp.63-72
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• 2020

This study aims to develop a video-based smart utterance deep analyser (SUDA) application that analyzes semiautomatically the utterances that child and mother produce during interactions over time. SUDA runs on the platform of Android, iPhones, and tablet PCs, and allows video recording and uploading to server. In this device, user modes are divided into three modes: expert mode, general mode and manager mode. In the expert mode which is useful for speech and language evaluation, the subject's utterances are analyzed semi-automatically by measuring speech and language factors such as disfluency, morpheme, syllable, word, articulation rate and response time, etc. In the general mode, the outcome of utterance analysis is provided in a graph form, and the manger mode is accessed only to the administrator controlling the entire system, such as utterance analysis and video deletion. SUDA helps to reduce clinicians' and researchers' work burden by saving time for utterance analysis. It also helps parents to receive detailed information about speech and language development of their child easily. Further, this device will contribute to building a big longitudinal data enough to explore predictors of stuttering recovery and persistence.

• Journal of the HCI Society of Korea
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• v.5 no.1
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• pp.37-43
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• 2010

Twitter has been continuously growing since October, 2006. Especially, not only the users and the number of messages have been increasing but also a new concept in social networking called 'micro blogging' has diffused. Within Korea, service such as 'me2day' has already been introduced and the improvement of internet accessibility within mobile devices is expected to expand the 'micro blogs'. In this point, this research is executed to study the new medium, 'micro blog'. To do so, we collected and analyzed Twitter logs of Korean users. Especially, we were curious about the extreme heavy users using Twitter, despite of the linguistic and cultural barrier of the foreign service. Who they are, why and how they use the 'micro blog'. First, we reviewed the general aspect of followers and messages by collecting a certain number of random samples. Using the Lorenz curve we found out that there was the imbalance within the users and based on this phenomenon we deducted an extreme heavy user group. In order to perform further analysis, log analysis was performed on the extreme heavy users. As the result, the users used multiple mobile and desktop 'Twitter' clients. The usage pattern was similar to that of internet usage time but was used during their "micro" time. The users using 'Twitter' not only to spread messages about important information, special events and emotions, but also as a habitual 'chatting tool' to express ordinary personal chats similar to SMS and IM services. In this research, it is proved that 68% of the total messages were ordinary personal chats. Also, with 24% of the total messages were retweets, we were able to find out that virtually connected 'people' and 'relationships' acted as the dominant trigger of their articulation.

• 한국지구과학회:학술대회논문집
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• 2005.02a
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• pp.239-248
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• 2005

이 논문은 과학영재교육원의 학생 선발과정을 중심으로 과학영재아 판별과정을 분석해보고, 과학영재교육원의 학생 선발과정에서 발생할 수 있는 오류를 점검하여, 이를 보완할 수 있는 개선안을 마련하고자 하는데 목적을 두고 있다. 분석결과 과학, 수학과 관련된 창의적 문제의 지필평가 성적이 선발의 가장 중요한 기준이었다. 지필평가 단계에서 지망분야에 관계없이 과학, 수학 및 창의력검사를 모두 치러야 하는 교육원에 초점을 맞추어 그 점수 활용에 있어서 발생할 수 있는 오류를 점검하였다. A 교육원의 경우 학생 선발은 다단계 평가를 원칙으로 하고 있었으며, 1단계 지필평가에서 과학, 수학, 창의력검사라는 세 과목 시험의 합산점수로서 선발하고 있었다. 이 교육원의 ○○년도 중등과정 응시자 276명을 대상으로 합격자와 불합격자의 지필평가 점수를 분석하여 과학, 수학, 창의력검사의 시행에 오류가 없었는지 점검하였다. 또 이들의 합산에 의한 선발이 의미 있는 결과를 보이는지 분석하였다. 그 결과 과학, 수학, 창의력검사의 상관도분석에서 과학은 수학 및 창의력검사와 유의미한 상관이 있었으나, 수학과 창의력검사는 독립적으로 분석되었다. 또 이들의 합산에 지원분야별 배점으로 계산한 선발은 본래의 취지, 즉 과학, 수학, 창의력에서 모두 우수한 학생을 선발하고자 하는 의도대로 진행되었으나, 판별분석 결과 합격과 불합격자 판별에서 88.1%의 정확도를 보여 다소 오류가 있었음을 발견하였다. 이는 해당년도에 출제된 문제의 난이도 및 시험 과목별 평균점수 차를 고려하지 않아 발생하는 문제로 파악되어져 원점수 대신 표준점수로 변환하여 오류를 보완할 것을 제안한다. 자체와 직접 관련되는 영역으로는 좌반구의 측두엽과 전두엽 부분이 관찰되었다. 특히 한국어 어말어미 산출시 나타나는 형태점화 양상과 관련된 대뇌영역으로 발견된 브로카 영역에서의 활성화는 어미 변환과 관련된 영역이라기보다는 산출시 관련되는 articulation, motor coordinate관련 영역으로 추정되고, 측두엽의 활성화는 형태소, 의미 관련 지식의 data base로 추정된다. 또한 우반구 전두엽 부분에서 관찰된 활성화는 억제관련 영역으로 짐작된다.러한 동물실험이 그 기초를 제공해 줄 수 있을 것이다. 또한 행동성향 및 기억의 종류에 따른 약물효과의 차이는 기억과 관련된 질병인 알츠하이머 환자에 있어 개개인에게 맞는 적절한 특징적인 치료약물이 존재할 것이라는 가능성을 제공해줄 뿐만 아니라 학습과 기억력 증진 효과를 기대해 볼 수 있을 것이라고 생각된다. 및 지역산업발전의 기획${\sim}$조정기구로서, 선진국의 지역발전기구(Regional Development Agency : RDA)인 지역전략산업기획단이 2002년도부터 산업자원부와 9개 시도에 의해 설립되어 지역네트워크의 활성화와 클러스터의 형성 촉진을 하게 되었고 2004년도에는 13개시도로 확대${\sim}$운영되고 있고, 지역특화사업(H/W)과 지역산업기술개발과제(S/W)와 함께 패케지 형태로 지원되며, 주요역할은 크게 지역산업의 정책기획 분야와 평가관리, 지역혁신역량 조사 및 DB구축 등으로 구분된다. 그중에서도 권역별, 지역별, 지역산업진흥사업 육성과 중장기 산업발전계획을 수립하기 위하여 지역혁신역량을 바탕으로 한 지역 Technol

• The KIPS Transactions:PartB
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• v.15B no.3
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• pp.179-188
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• 2008

In this paper, knowledge based text to facial sequence image system for interaction of lecturer and learner in cyber universities is studied. The system is defined by the synthesis of facial sequence image which is synchronized the lip according to the text information based on grammatical characteristic of hangul. For the implementation of the system, the transformation method that the text information is transformed into the phoneme code, the deformation rules of mouse shape which can be changed according to the code of phonemes, and the synthesis method of facial sequence image by using deformation rules of mouse shape are proposed. In the proposed method, all syllables of hangul are represented 10 principal mouse shape and 78 compound mouse shape according to the pronunciation characteristics of the basic consonants and vowels, and the characteristics of the articulation rules, respectively. To synthesize the real time facial sequence image able to realize the PC, the 88 mouth shape stored data base are used without the synthesis of mouse shape in each frame. To verify the validity of the proposed method the various synthesis of facial sequence image transformed from the text information is accomplished, and the system that can be applied the PC is implemented using the proposed method.

• Korean Journal of Head & Neck Oncology
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• v.19 no.1
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• pp.41-46
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• 2003

Background and Objectives: Surgical ablation of tumors in the oral cavity and the oropharynx results in a three dimensional defect because of the needs to resect the adjacent area for the surgical margin. Although a variety of techniques are available, radial forearm free flap has been known as an effective method for this defect, which offers a thin, pliable, and relatively hairless skin and a long vascular pedicle. We report the clinical results of our 54 consecutive radial forearm free flaps used for oral cavity and oropharynx cancers. Materials and Methods: We reviewed the medical records of patients who were offered intraoral reconstruction with a radial forearm free flap after ablative surgery for oral cavity and oropharyngeal cancers from August 1994 to February 2003 and analyzed surgical methods, flap survival rate, complication, and functional results. Among these, 20 cases were examined with modified barium swallow to evaluate postoperative swallowing function and other 8 cases with articulation and resonance test for speech. We examined recovery of sensation with two-point discrimination test in 15 cases who were offered sensate flaps. Results: The primary sites were as follows : mobile tongue (18), tonsil (17), floor of mouth (4), base of tongue (2), soft palate (2), retromolar trigone (3), buccal mucosa (1), oro-hypopharynx (6), and lower lip (1). The paddles of flaps were tailored in multilobed designs from oval shape to tetralobed design and in variable size according to the defects after ablation. This procedures resulted in satisfactory flap success rate (96.3%) and showed good swallowing function and social speech. Eight of 15 cases (53.3%) who had offered sensate flap showed recovery of sensation between 1 and 6 postoperative months (average 2.6 month). Conclusion: The reconstruction with radial forearm free flap might be an excellent method for the maximal functional results after ablative surgery of oral cavity and oropharyngeal cancers that results in multidimensional defect.

• Cross-Cultural Studies
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• v.20
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• pp.5-27
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• 2010

This paper studies the relation between canonical/variegated babble (CB/VB) and early speech in an infant acquiring Mandarin Chinese from 9 to 17 months. The infant was audio-and video-taped in her home almost every week. The data analyzed here come from 1,621 utterances extracted from 23 sessions ranging from 30 minutes to one hour, from age 00:09;07 to 01:05;27. The data was digitized, and segments from 23 sessions were transcribed in narrow IPA and coded for analysis. Babble was coded from age 00:09;07 to 01:00;00, and words were coded from 01:00;00 to 01:05;27, proto-words appeared at 11 months, and some babble was still present after 01:10;00. 3821 segments were counted in CB/VB utterances, plus the segments found in 899 word tokens. The data transcription was completed and checked by the author and was rechecked by two other researchers who majored in Chinese phonetics in order to ensure the reliability, we reached an agreement of 95.65%. Mandarin Chinese is phonetically very rich in consonants, especially affricates: it has aspirated and unaspirated stops in labial, alveolar, and velar places of articulation; affricates and fricatives in alveolar, retroflex, and palatal places; /f/; labial, alveolar, and velar nasals; a lateral;[h]; and labiovelar and palatal glides. In the child's pre-speech phonetic repertoire, 7 different consonants and 10 vowels were transcribed at 00:09;07. By 00:10;16, the number of phones was more than doubled (17 consonants, 25 vowels), but the rate of increase slowed after 11 months of age. The phones from babbling remained active throughout the child's early and subsequent speech. The rank order of the occurrence of the major class types for both CB and early speech was: stops, approximants, nasals, affricates, fricatives and lateral. As expected, unaspirated stops outnumbered aspirated stops, and front stops and nasals were more frequent than back sounds in both types of utterances. The fact that affricates outnumbered fricatives in the child's late babble indicates the pre-speech influence of the ambient language. The analysis of the data also showed that: 1) the phonetic characteristics of CB/VB and early meaningful speech are extremely similar. The similarities of CB/VB and speech prove that the two are deeply related; 2) The infant has demonstrated similar preferences for certain types of sounds in the two stages; 3) The infant's babbling was patterned at segmental level, and this regularity was similarly evident in the early speech of children. The three types being coronal plus front vowel; labial plus central and dorsal plus back vowel exhibited much overlap in the phonetic forms of CB/ VB and early speech. So the child's CB/ VB at this stage already shared the basic architecture, composition and representation of early speech. The evidence of similarity between CB/VB and early speech leaves no doubt that phones present in CB/VB are indeed precursors to early speech.

• 재활복지
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• v.18 no.4
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• pp.237-255
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• 2014

Idiopathic Parkinson disease(IPD) is an neurodegenerative disease caused by the loss of dopamine cells in the substantia nigra, a region of midbrain. Its major symptoms are muscular rigidity, bradykinesia, resting tremor, and postural instability. An estimated 70~90% of patients with IPD also have hypokinetic dysarthria. Subthalamic nucleus deep brain stimulation (STN-DBS) has been reported to be successful in relieving the core motor symptoms of IPD in the advanced stages of the disease. However, data on the effects of STN-DBS on speech performance are inconsistent. A medline literature search was done to retrieve articles published from 1987 to 2012. The results were narrowed down to focus on speech performance under STN-DBS based perceptual, acoustic, and/or aerodynamic analyses. Among the 32 publications which dealt with speech performance after STN-DBS indicated improvement(42%), deterioration(29%), mixed results(26%), or no change(3%). The most favorite method was found to be based upon acoustic analysis by using a vowel prolongation and Unified Parkinson's Disease Rating Scale(UPDRS). For the purpose of verifying the effect of the STN-DBS, speech evaluation should be undertaken on all speech components such as articulation, resonance, phonation, respiration, and prosody by using a contextual speech task.

• 한국노년학
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• v.32 no.3
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• pp.747-758
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• 2012

Detecting probable Alzheimer's disease (AD) at an early stage is crucial in slowing the progression of the disease and initiating drug therapy for more effective symptom management. Therefore, this study aimed to identify linguistic features that allow us to distinguish between patients with AD and normal controls. This paper reports on characteristics of spontaneous speech in subjects in three stages of AD (questionable, mild, moderate) compared with education- and age-matched normal controls. Four components of speech were measured in Korean native speakers with AD and normal aging: speech tempo, hesitation (measured in seconds), rate of articulation errors, and rate of grammatical errors. The results revealed significant differences in most of these speech components among the four groups, including significant differences between normal controls and the questionable AD group in the areas of speech tempo and rate of grammatical errors. Phonological? articulatory ability was preserved in questionable AD, and grammatical ability was preserved in questionable and mild AD. Subjects with moderate AD were severely impaired in grammatical ability. Prospective assessments of spontaneous speech skills using a dialogue and picture-description task are useful in detecting the subtle, spontaneous speech impairments that AD causes even in its early stage.

• Therapeutic Science for Rehabilitation
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• v.8 no.2
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• pp.67-78
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• 2019

Objective : The purpose of this study was to investigate the effect of hand tapping on the accuracy and the fluency of speech production in children with speech sound disorder(SSD) and their typically developing peers(TD). Methods : The study subjects were 15 SSD children and 15 TD children aged 4, 5, and 6 years of age. Subjects were asked to give a picture name without hand tapping in the first experimental condition, and with hand tapping in the second experiment condition. Results : The results showed that hand tapping significantly increased disfluency in TD, whereas in SSD. it did not affect the accuracy or fluency of speech production. In addition, TD demonstrated a significant positive correlation with the changes of accuracy and disfluency due to hand tapping, whereas SSD had no correlation. Conclusion : We discussed the possibility that hand tapping could serve as an obstacle distracting attention from SSD and TD, acting as a motor gesture to facilitate phonological processing when facing the difficulty in lexical retrieval for SSD.