• Journal of Magnetics
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• 제20권1호
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• pp.47-51
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• 2015

We measured radial arterial pulse signals using a prototype of a clip-type pulsimeter equipped with a permanent magnet and a Hall device, which produced signals through a voltage-detecting circuit. The systolic peak time and the reflective peak time for a temporally pulsed signal were analyzed for an arbitrary pulse wave at one position of a small permanent magnet. The measured value of the peripheral pulse wave velocity was about 1.25-1.52 m/s, demonstrating the accuracy of this new method. To measure the peripheral blood flow velocity, we simultaneously connected the radial artery pulsimeter to a photoplethysmography meter. The average value of the peripheral blood flow velocity was about 0.27-0.50 m/s.

• JSTS:Journal of Semiconductor Technology and Science
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• 제16권5호
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• pp.702-712
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• 2016

A wrist watch type wearable cardiovascular monitoring device is proposed for continuous and convenient monitoring of the patient's cardiovascular system. For comprehensive monitoring of the patient's cardiovascular system, the concurrent electrocardiogram (ECG) and arterial pulse wave (APW) sensor front-end are fabricated in $0.18{\mu}m$ CMOS technology. The ECG sensor frontend achieves 84.6-dB CMRR and $2.3-{\mu}Vrms$-input referred noise with $30-{\mu}W$ power consumption. The APW sensor front-end achieves $3.2-V/{\Omega}$ sensitivity with accurate bio-impedance measurement lesser than 1% error, consuming only $984-{\mu}W$. The ECG and APW sensor front-end is combined with power management unit, micro controller unit (MCU), display and Bluetooth transceiver so that concurrently measured ECG and APW can be transmitted into smartphone, showing patient's cardiovascular state in real time. In order to verify operation of the cardiovascular monitoring system, cardiovascular indicator is extracted from the healthy volunteer. As a result, 5.74 m/second-pulse wave velocity (PWV), 79.1 beats/minute-heart rate (HR) and positive slope of b-d peak-accelerated arterial pulse wave (AAPW) are achieved, showing the volunteer's healthy cardiovascular state.

• The Journal of Korean Physical Therapy
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• 제11권2호
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• pp.37-42
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• 1999

The purpose of this study was to determine whether percutaneous interferential current stimulation on thoracic sympathetic ganglia with amplitude modulated frequency (AMF) $90\~100$ bps and subthreshold of muscle contraction for 10 minutes on peripheral blood flow velocity in healthy subjects. Thirty-seven healthy volunteers were assigned randomly into an experimental group (n=25) and a control group (n=12). the experimental group received interferential current stimulation with subthreshold of the muscle contraction of current at AMF $90\~100$ bps on $1st\~5th$ thoracic sympathetic ganglial region for 10 minutes. The control group received same handling and electode placement, but no current was applied. Using a Doppler blood flow meter, the radial arterial blood flow velocities and the pulse raters were determined for two-way analysis of variance for repeated measures on time and group. There were no significant difference between the two groups with respect to the changes in arterial blood flow velocity and pulse rate over the four measurement times. Interferential current stimulation did not change in mean blood flow velocity and pulse rate. We conclude that interferential current stimulation on the thoracic sympathetic ganglia, as used in this study, did not dilate peripheral artery. This results suggests that interferential current stimulation dose not alter the activtiy of sympathetic nerve.

• Archives of Plastic Surgery
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• 제40권5호
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• pp.505-509
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• 2013

Background The aim of this study was to collect important data on the time of oxygen saturation change in relation to skin flap color alteration using non-invasive pulse oximetry to evaluate its ability to provide continuous monitoring of skin flap perfusion. Methods An experimental study on the monitoring of blood perfusion of 20 tube-island groin flaps of 10 male New Zealand rabbits was performed using pulse oximetry. The animals were randomly assigned to one of two groups representing a blockage of either arterial or venous blood flow. The oxygen saturation change and clinical color alteration were monitored from the beginning of vessel clamping until the saturation became undetectable. The result was analyzed by the t-test using SSPS ver. 10.0. Results The mean times from the vessel clamping until the saturation became undetectable were $20.19{\pm}2.13$ seconds and $74.91{\pm}10.57$ seconds for the artery and vein clamping groups, respectively. The mean time of the clinical alteration from the beginning of vein clamping was $34.5{\pm}11.72$ minutes, while the alteration in flaps with artery clamping could not be detected until 2.5 hours after clamping. Conclusions The use of neonate-type reusable flex sensor-pulse oximetry is objective and effective in early detection of arterial and vein blockage. It provides real-time data on vessel occlusion, which in turn will allow for early salvaging. The detection periods of both arterial occlusion and venous congestion are much earlier than the color alteration one may encounter clinically.

• 디지털융복합연구
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• 제11권3호
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• pp.337-344
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• 2013

본 연구의 목적은 유산소성 운동프로그램 참여가 시각장애인의 호흡순환기능 및 동맥파속도에 어떠한 영향을 미치는가를 규명하기 위한 목적으로 수행되었다. 본 연구의 목적을 인지하고 참여의사를 밝힌 1급 시각장애인 20명이었으며, 보호자를 통하여 피험자 참여의 동의서를 받았다. 이들은 유산소성운동집단 10명과 통제집단 10명으로 무선배정으로 분류하였다. 유산소성운동집단은 12주동안 50-70%HRmax 강도로 주 5회 1일 준비운동, 본운동, 정리운동 총 60분으로 실시하였다. 본 연구의 자료처리는 독립변인으로 한 반복측정에 의한 이원변량분석(two-way repeated ANOVA)을 실시하였으며, 상호작용 효과를 검증하기 위해 paired t-test를 실시하였으며, 통계적 유의수준은 p<.05로 설정하여 다음과 같은 결론을 얻었다. 첫째, 실험집단에서 체중과 체지방률은 사전과 비교하여 사후 유의한 감소를 나타냈다(p<.05). 둘째, 실험집단에서 최대산소섭취량, 최대심박수, 최대환기량은 사전과 비교하여 사후 유의한 증가를 나타냈다(p<.05). 셋째, 실험집단에서 동맥파속도는 사전과 비교하여 유의한 증가를 나타냈다(p<.05), 넷째, 실험집단에서 수축기혈압은 사전과 비교하여 사후 유의한 감소를 나타내지 않았다(p>.05). 이상의 결과를 종합해 볼 때 유산소성 운동프로그램 참여는 호흡순환기능 및 혈류순환과 혈관기능 개선에 효과적으로 나타났다.

• 디지털융복합연구
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• 제15권7호
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• pp.407-414
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• 2017

본 연구는 융복합 유산소운동이 비만 여자대학생의 동맥맥파속도, 호흡순환계 및 신체조성에 미치는 영향을 규명하기 위해 D광역시 Y구에 위치한 D대학교 여자대학생을 대상으로 체지방율 수치가 30% 이상인자, 과거와 현재 특별한 질환이 없고, 규칙적인 신체활동 경험이 없는 26명을 선정하여 실험 목적과 내용을 충분히 설명한 후 참여 동의서를 받음으로써 최종 확정한 뒤, 운동집단(N=13), 통제집단(N=13)으로 무선배정 하고 12주간 유산소운동을 실시하였으며, 다음과 같은 결론을 얻었다. 첫째, 신체조성의 변화는 운동집단에서 체중, 체지방율, 복부지방율이 유의하게 감소를 보였다. 둘째, 호흡순환계의 변화는 운동집단에서 최대산소섭취량, 최대심박수, 최대환기량은 유의한 증가를 보였다. 셋째, 동맥맥파속도의 변화는 운동집단에서 상체(왼손, 오른손), 하체(왼발, 오른발)에서 유의한 감소를 보였다.

• 대한한의진단학회지
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• 제11권1호
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• pp.48-60
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• 2007

Palpation of the pulse has been used in Korean traditional medicine since ancient times to assess physical health. Pulse wave contour may be obtained by measuring arterial pressure or blood volume change of skin. The latter is called as Photoplethysmography(PPG) or digital volume pulse(DVP). The PPG signal is measured by a device comprising an infrared light sourece and a photodetector. Although less widely used, this technique deserves further consideration because of its simplicity and ease of use. The contour of the PPG is formed as a result of a complex interaction between the left ventricle and the systemic circulation. It usually exhibits an early systolic peak and an early diastolic peak. the first peak is formed mainly by pressure trasmitted along a direct path from the left ventricle to the finger. The second peak is formed in part by pressure transmitted along the aorta and large arteries to sites of impedance mismatch in the lower body. The contour of the PPG is sensitive to changes in arterial tone and is influenced by ageing and large artery stiffness. Measurements taken directly from the PPG or from its second derivative can be used to assess these properties. In some mathematical approaches, the extraction of periodic components using frequency analysis was tried to analysis of the PPG. But we don't understand yet what kind of factor in the cardiovascular system or human body is related with the respective specific Fourier components of PPG. This review describes the background to measurement principles, representative contour, contour analysis and frequency domain analysis of PPG, and current and future.

• 한국방사선학회논문지
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• 제9권4호
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• pp.213-217
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• 2015

스텐트 삽입술을 시행한 환자에게 ASL 방법 중 pCASL을 이용한 관류영상에서 나타난 인공물을 보고하고 이에 대한 해결방법을 제시하고자 한다. pCASL데이터는 구조적 이미지와 함께 스텐트를 피해 표지 펄스(labeling pulse)의 위치를 변경하여 획득하였다. 데이터는 ASLtbx를 이용하여 처리하였다. pCASL을 이용하여 관류영상을 획득하였을 때 기존의 표지 펄스(표지 간격(labeling gap) 24 mm)의 위치가 스텐트의 위치와 겹쳐져서 우뇌 조직의 신호강도가 비어 있는 것처럼 나타났다. 스텐트를 피해 표지 펄스(표지 간격 15 mm)를 위치시킬 때 높은 신호강도의 영상을 획득할 수 있었으며, 표지 펄스(표지 간격 170 mm)에서는 labeled 혈액이 영상절편에 도달하기 전에 이완이 되어 낮은 신호강도의 영상을 획득 하였다. pCASL은 조영제를 사용하지 않기 때문에 안정적으로 반복측정이 가능하며 양질의 영상 획득을 위해서는 알맞은 영상획득인자와 방법들이 선택되어야 한다.

• 대한전자공학회:학술대회논문집
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• 대한전자공학회 1998년도 하계종합학술대회논문집
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• pp.573-576
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• 1998

In this paper, we devised pulse detection transducer that has non-differential characteristics for pulse detection on chongu arterial. The transducer consist of load cell and driving electronic circuits. Load cell consist of cantilever and two metal film strain gauge. The pressure signal from chongu artery is delivered to load cell using artery rider that attached to cantilever. Therefore the pressure pulse signal can obtain by the developed transducer. As the results of experiment, the developed transducer has a good linearity at pressure to voltage conversion and acan detect non-differential pulse signal from chongu artery.

• 대한한의진단학회지
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• 제16권1호
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• pp.19-26
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• 2012

Objectives The aim of this study is to develop a cardiovascular simulator that can reproduce blood pressure pulse and blood flow similar to those of the human body. Methods In order to design a system similar to the human cardiovascular system, the required performances were determined by investigating the hemodynamic characteristics of the heart and the arterial system. Main organ to be imitated is heart in simulator. The rest of the system was minimally designed. Also, a blood pressure and blood flow measurement system was developed for measuring the results. Results The developed system showed blood pressure pulse at similar range of the human aorta. The result waveform include primary wave caused by ventricular systole except reflected wave. Conclusions The blood pressure and blow flow patterns were replicated by the simulator. These patterns were similar to those of the human body. The system will play an important role in studying pulse diagnostics.