• Journal of Applied Biological Chemistry
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• v.51 no.1
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• pp.36-44
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• 2008

Organic forms of arsenic (As) were determined through fractionation procedure of soil organic matter (SOM) in soil, sediments and mine tailing samples from the Myungbong, Dongil, and Okdong mining areas of southern Korea. An alkaline extraction method was applied to soil samples followed by the fractionation procedures of SOM by the DAX-8 and XAD-4 resin adsorption method. Major fraction of organic As species (42% to 98%) was found in acid-soluble fraction, whereas minor fraction (0.1 % to 67.8%) was present in the humic-associated As. In acid-soluble fractions, the transphillic- and hydrophilic-associated As were dominant in addition to As binding with humic and fulvic SOM. Arsenic binding was the strongest between pH 6 to 8 and reduced to about 70% at both low and high pH regions. The amount of both transphillic and hydrophillic associated As was less changed than humic and fulvic-associated As, in both low and high pH regions. This apparently indicates that As has stronger affinity towards hydrophillic rather than hydrophobic organics. From the experimental observation of As-binding SOM in natural soil, the ligand exchange model may be a feasible explanation of transphillic and hydrophillic affinity of As.

• Proceedings of the Korean Society of Toxicology Conference
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• 2002.05a
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• pp.106-106
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• 2002

Several epidemiological studies suggested that arsenic exposure was strongly correlated with the development of cardiovascular disease such as hypertension. In order to examine whether arsenic affects vasomotor tone in blood vessels, we investigated the effect of arsenic on agonist-induced vasorelaxation using the isolated rat aortic rings in in vitro organ bath system.(omitted)

• Proceedings of the Korean Society of Toxicology Conference
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• 2002.11b
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• pp.155-155
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• 2002

Several epidemiological studies have suggested that exposure to arsenic is strongly correlated with the development of cardiovascular diseases such as hypertension. To determine whether arsenic affects vasomotor tone in blood vessels, we investigated the effect of arsenic on vasorelaxation using isolated rat aortic rings in an organ bath system.(omitted)

• Proceedings of the Korean Society of Toxicology Conference
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• 2002.11b
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• pp.156-156
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• 2002

Chronic exposure of arsenic is well known to be the cause of cardiovascular disease such as hypertension. In order to investigate the effect of arsenic on blood vessels, we examined whether arsenic affected agonist-induced contraction of aortic rings in isolated organ bath system.(omitted)

• Bulletin of the Korean Chemical Society
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• v.27 no.6
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• pp.903-908
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• 2006

Various extraction procedures were investigated using reference materials and samples to evaluate extraction efficiency and effectiveness. Inductively coupled plasma mass spectrometry (ICP-MS) was used to measure total arsenic and to quantitate arsenic species when coupled to an HPLC (high pressure liquid chromatography). Arsenic species were extracted from rice flour (NIST SRM 1568a) with water/methanol mixtures using accelerated solvent extraction (ASE). Total arsenic extraction efficiency ranged from 42 to 64%, for water and various methanol concentrations. From spinach (NIST SRM 1570), freeze-dried apple, and rice flour (NIST SRM 1568a), arsenic species were extracted with trifluoroacetic acid (TFA) at 100 ${^{\circ}C}$. Total arsenic extraction efficiency was 90% for spinach, 75% for freeze-dried apple, and 83% for rice flour. Enzymatic extraction with alpha-amylase and sonication resulted in extraction efficiency of 104% for rice flour, 98% for freeze-dried apple, and 7% for spinach. Chromatograms of arsenic species extracted by the optimum extraction methods were obtained, and the species were quantified. Arsenite (As(III)), arsenate (As(V)), dimethylarsinic acid (DMA), and monomethylarsonic acid (MMA) were found in the apple sample, and DMA and As(V) in the rice flour sample. As(V) and MMA were found in three herbal dietary supplement samples.

• Reproductive and Developmental Biology
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• v.38 no.3
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• pp.107-114
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• 2014

Oral exposure of humans by excess amounts of arsenic may cause disturbances of the reproductive system. In the present study, such exposure was modelled in rats, with the support of sperm principal parameters and histopathological observations. Male Sprague-Dawley rats were randomly divided into three groups where the group I was served as a normal control, group II was received sodium meta-arsenite as arsenic (10 mg/kg b.w/day) and a combination of sodium meta-arsenite and sodium selenite (3 mg/kg b.w/day) in group III. After 6 weeks, there was no significant change in testis weight and in total motility of all the three experimental groups, whereas, rapid moving spermatozoa, moderately moving spermatozoa and slow moving spermatozoa were significantly decreased in arsenic treated rats as compared to control rats. The other sperm principal parameters like progressiveness, average path velocity, straightness linear velocity (VSL), curvilinear velocity (VCL), straightness, linearity sperm head elongation ratio, area, linearity amplitude of lateral head department (ALH) and beat cross frequency (BCF) were found to be reduced in arsenic intoxicated rats. These results are not correlated with the histological studies. On oral administration of selenium ameliorated the adverse effects of arsenic as compared to arsenic alone treated rats. Our findings clearly demonstrate that administration of selenium could prevent some of the deleterious effects of arsenic in the testis.

• Economic and Environmental Geology
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• v.38 no.5 s.174
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• pp.599-606
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• 2005

Arsenic is a significantly toxic contaminant in groundwater in many countries. Numerous treatment technologies have been developed to remove arsenic from groundwater. The USEPA recommends several technologies as the best available technology (BAT) candidates for the removal of arsenic. Based on the USEPA classification, arsenic treatment technologies can be divided into four technologies such as precipitation, membrane, ion exchange, and adsorption technology. The recent amendment of arsenic drinking water standard from 50 to $10{\mu}g/L$ in the United States have impacted technology selection and application for arsenic removal from arsenic contaminated groundwater. Precipitation technology is most widely used to treat arsenic contaminated groundwater and can be applied to large water treatment facility. In contrast, membrane, ion exchange, and adsorption technologies are used to be applied to small water treatment system. Recently, the arsenic treatment technology in the United States and Europe move towards adsorption technology to be applied to small water treatment system since capital and maintenance costs are relatively low and operation is simple. The principals of treatment technologies, effect factors on arsenic removal, arsenic treatment efficiencies of real treatment systems are reviewed in this paper.

• Proceedings of the Korean Society of Soil and Groundwater Environment Conference
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• 2003.04a
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• pp.314-317
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• 2003

The overall objective of the adsorption study of arsenic was to elucidate the ability of iron coated sand(ICS), synthesized in the laboratory, to remove arsenic from polluted waters. Batch tests were conducted to provide a relation between arsenic removal and iron content of ICSs. The ICS, developed in the laboratory by coating iron onto the surface of ordinary sand by a simple and easy process has proved as an effective medium for use in removal of arsenic from waters over a wide range of particle sizes of ICS. The composite media is inexpensive to prepare and could serve as the basis of a useful arsenic removal process in variety settings.

• Asian Pacific Journal of Cancer Prevention
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• v.16 no.8
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• pp.3183-3188
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• 2015

Objective: This study aimed to evaluate the prevalence of skin lesions, which is a health effect of chronic arsenic (As) exposure, and determine the hair/blood arsenic concentrations of people living in Kutahya villages who are using and drinking tap water with a high concentration of arsenic. Materials and Methods: A total of 303 people were included in the present cross-sectional study. A prepared questionnaire form was used to collect the participants' information and environmental history. Skin examination was performed on all participants. Hair, blood and water samples were analyzed using atomic absorption spectroscopy. The cumulative arsenic index (CAI) was calculated for all participants. Results: Villages were divided into two groups according to the arsenic level (<$20{\mu}g/L$, Group I; >$20{\mu}g/L$, Group II) in their water. The prevalence of skin lesions, hair and blood arsenic level, and CAI were found to be higher in the Group II participants. There was a positive association between body arsenic levels and CAI in the participants of each group. Conclusions: The number of skin lesions and arsenic concentrations in body samples were found to increase with the water arsenic level and exposure time. We hope that sharing this study's results with local administrators will help accelerate the rehabilitation of water sources in Kutahya.

• Economic and Environmental Geology
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• v.37 no.6 s.169
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• pp.657-667
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• 2004

Arsenic was detected in the 29 water samples out of the 46 groundwaters located in the Ulsan metropolitan area and it's concentration ranges from $<0.1\;to\;72{\mu}g/L$. Among them the arsenic concentrations of three samples are over domestic drinking-water requirements $(50{\mu}g/L)$, and those of 10 samples are more than WHO MCLs, $10{\mu}g/L.$. High arsenic groundwater were recognized in the two region; one was near the tectonic line, especially Ulsan iron mine at Dalcheunri and the other was around Hyomundong distributed Jeongia conglomerate. It is estimated that the former is originated from pyrite oxydation type, oxygenated redox, whilst the latter is resulted from oxidation of reducted FeOOH. The species of arsenic in groundwater is in pentavalent arsenic, $H_2AsO_4^-,\;HAsO4_^{-2}$ near tectonic line, and trivalent arsenic, $H_3AsO_3$ around Hyomundong.