• Proceedings of the IEEK Conference
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• 2001.06e
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• pp.89-92
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• 2001

For the diagnosis of arrhythmia in the heart system, the QRS complex of ECG signals is used in many cases. The rejection of the noise in ECG signals is important to acquisition of exact QRS complex. This paper presents some experimental results about instantaneous bandwidth estimation and noise rejection of ECG signals with the purpose of rejection of the 60 Hz power noise and the motion artifacts such as EMG signals and contact noise. ECG signals corrupted by noise are cleaned by using the variable bandwidth filter. For the filtering of ECG signals with noise, the instantaneous bandwidth of the signals is estimated by analysis of time-frequency representation of ECG signal.

• Journal of information and communication convergence engineering
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• v.5 no.1
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• pp.7-11
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• 2007

The aim of this paper is to design and implement a new ECG signal monitoring and analysis method for the home care of elderly persons or patients, using wireless sensor network (WSN) technology. The wireless technology for home-care purpose gives new possibilities for monitoring of vital parameter with wearable biomedical sensors and will give the patient freedom to be mobile and still be under continuously monitoring. Developed platform for portable real-time analysis of ECG signals can be used as an advanced diagnosis and alarming system. The ECG features are used to detect life-threatening arrhythmias, with an emphasis on the software for analyzing the P-wave, QRS complex, and T-wave in ECG signals at server after receiving data from base station. Based on abnormal ECG activity, the server transfer diagnostic results and alarm conditions to a doctor's PDA. Doctor can diagnose the patients who have survived from arrhythmia diseases.

• Journal of Chest Surgery
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• v.16 no.3
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• pp.368-374
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• 1983

Combined type of primary lung cancer is a very rare form in clinical experience, which is 3 histologically different variants of bronchogenic carcinoma. These type had a well differentiated squamous carcinoma forming keratin pearls, well differentiated adenocarcinoma and pleomorphic undifferentiated cell carcinoma, usually small cell carcinoma. The patient, a male, 49-Y-0, was complaint coughing, mild dyspnea, blood tinged sputum and chest pain. Under diagnosis of lung cancer preoperatively, the right total pneumonectomy was performed with very difficulty such as arrhythmia, ventilation impairment during post operation course. The histology of specimen was disclose as 3 different histological type, combined lung cancer as squamoadenoundifferentiated carcinoma. The mediastinal nodes were freed from metastasis but the parietal pleural metastatic loci was found. The radio & chemotherapy were performed post-operatively. The patient had been experienced empyema at post-pneumonectomy space and then open drainage procedure and thoracoplasty had been added for treatment course. The patient is alive recently.

• The Korean journal of internal medicine
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• v.39 no.5
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• pp.717-730
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• 2024

Elevated blood cholesterol and triglyceride levels induced by secondary causes are frequently observed. The identification and appropriate handling of these causes are essential for secondary dyslipidemia treatment. Major secondary causes of hypercholesterolemia and hypertriglyceridemia include an unhealthy diet, diseases and metabolic conditions affecting lipid levels, and therapeutic side effects. It is imperative to correct secondary causes prior to initiating conventional lipid-lowering therapy. Guideline-based lipid therapy can then be administered based on the subsequent lipid levels.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.19 no.1
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• pp.192-200
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• 2015

Several algorithms have been developed to classify arrhythmia which rely on specific ECG(Electrocardiogram) database. Nevertheless personalized difference of ECG signal exist, performance degradation occurs because of carrying out diagnosis by general classification rule. Most methods require accurate detection of P-QRS-T point, higher computational cost and larger processing time. But it is difficult to detect the P and T wave signal because of person's individual difference. Therefore it is necessary to classify the pattern by analyzing personalized ECG signal and extracting minimal feature. Thus, QRS pattern Analysis of personalized ECG Signal by Q, R, S peak variability is presented in this paper. For this purpose, we detected R wave through the preprocessing method and extract eight feature by amplitude and phase variability. Also, we classified nine pattern in realtime through peak and morphology variability. PVC, PAC, Normal, LBBB, RBBB, Paced beat arrhythmia is evaluated by using 43 record of MIT-BIH arrhythmia database. The achieved scores indicate the average of 93.72% in QRS pattern detection classification.

• The Journal of the Society of Korean Medicine Diagnostics
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• v.11 no.1
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• pp.146-156
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• 2007

1. The effect of variations in inspiration and expiration times on heart rate variability was studied in 78 healthy subjects (mean age $24.35{\pm}1.92$ years; 47 male) between regulated respiration group and normal respiration group as the control group. 2. The control group followed normal respiration pattern, whereas the regulated group followed three types of respiration pattern. The first pattern was long respiration(E/I ratio 1.6:1), the second pattern was short inspiration followed by long expiration (SILE), and the last pattern was long inspiration followed by short expiration(LISE). The average expiration/inspiration time ratios of SILE and LISE were 1.0 and 3.4, respectively. The respiration rate in the regulated group was approximately 10 cycles/min. 3. Respiration rate and tidal volume are respiratory variables known to modulate RSA. The results of the present study indicate that RSA can also be modulated by a third respiratory variable, the expiration/inspiratory time ratio. In this study, LF, HF, RSA, VLF is increased the most in LISE group compared to the other groups. HF and RSA increased significantly in the long respiration rate and SILE groups. However LF and VLF, which reflects the sympathetic tones, did not increase as much as the LISE group.

• Childhood Kidney Diseases
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• v.14 no.2
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• pp.132-142
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• 2010

Hypokalemia usually reflects total body potassium deficiency, but less commonly results from transcellular potassium redistribution with normal body potassium stores. The differential diagnosis of hypokalemia includes pseudohypokalemia, cellular potassium redistribution, inadequate potassium intake, excessive cutaneous or gastrointestinal potassium loss, and renal potassium wasting. To discriminate excessive renal from extrarenal potassium losses as a cause for hypokalemia, urine potassium concentration or TTKG should be measured. Decreased values are indicative of extrarenal losses or inadequate intake. In contrast, excessive renal potassium losses are expected with increased values. Renal potassium wasting with normal or low blood pressure suggests hypokalemia associated with acidosis, vomiting, tubular disorders or increased renal potassium secretion. In hypokalemia associated with hypertension, plasam renin and aldosterone should be measured to differentiated among hyperreninemic hyperaldosteronism, primary hyperaldosteronism, and mineralocorticoid excess other than aldosterone or target organ activation. Hypokalemia may manifest as weakness, seizure, myalgia, rhabdomyolysis, constipation, ileus, arrhythmia, paresthesias, etc. Therapy for hypokalemia consists of treatment of underlying disease and potassium supplementation. The evaluation of hyperkalemia is also a multistep process. The differential diagnosis of hyperkalemia includes pseudohypokalemia, redistribution, and true hyperkalemia. True hyperkalemia associated with decreased glomerular filtration rate is associated with renal failure or increased body potassium contents. When glomerular filtration rate is above 15 mL/min/$1.73m^2$, plasma renin and aldosterone must be measured to differentiate hyporeninemic hypoaldosteronism, primary aldosteronism, disturbance of aldosterone action or target organ dysfunction. Hyperkalemia can cause arrhythmia, paresthesias, fatigue, etc. Therapy for hyperkalemia consists of administration of calcium gluconate, insulin, beta2 agonist, bicarbonate, furosemide, resin and dialysis. Potassium intake must be restricted and associated drugs should be withdrawn.

• Korean Circulation Journal
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• v.53 no.10
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• pp.693-707
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• 2023

Background and Objectives: Inherited arrhythmia (IA) is a more common cause of sudden cardiac death in Asian population, but little is known about the genetic background of Asian IA probands. We aimed to investigate the clinical characteristics and analyze the genetic underpinnings of IA in a Korean cohort. Methods: This study was conducted in a multicenter cohort of the Korean IA Registry from 2014 to 2017. Genetic testing was performed using a next-generation sequencing panel including 174 causative genes of cardiovascular disease. Results: Among the 265 IA probands, idiopathic ventricular fibrillation (IVF) and Brugada Syndrome (BrS) was the most prevalent diseases (96 and 95 cases respectively), followed by long QT syndrome (LQTS, n=54). Two-hundred-sixteen probands underwent genetic testing, and 69 probands (31.9%) were detected with genetic variant, with yield of pathogenic or likely pathogenic variant as 6.4%. Left ventricular ejection fraction was significantly lower in genotype positive probands (54.7±11.3 vs. 59.3±9.2%, p=0.005). IVF probands showed highest yield of positive genotype (54.0%), followed by LQTS (23.8%), and BrS (19.5%). Conclusions: There were significant differences in clinical characteristics and genetic yields among BrS, LQTS, and IVF. Genetic testing did not provide better yield for BrS and LQTS. On the other hand, in IVF, genetic testing using multiple gene panel might enable the molecular diagnosis of concealed genotype, which may alter future clinical diagnosis and management strategies.

• Journal of Veterinary Clinics
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• v.32 no.1
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• pp.101-104
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• 2015

A 4-years-old, intact male Golden retriever dog was presented with abdominal distension and dyspnea. Physical examination revealed arrhythmia and cardiac murmur. Generalized cardiomegaly, pleural effusion and ascites were shown on thoracic and abdominal radiographs. Two-dimensional echocardiography revealed abnormal mitral and tricuspid valve motion, mitral and tricuspid regurgitation, left ventricular eccentric hypertrophy and left atrial dilation. Color-flow Doppler imaging revealed turbulent flow extending into the left ventricle during diastole from the mitral valve orifice, and into the left atrium during systole. Spectral Doppler recordings revealed highly increased early diastolic mitral valve inflow and prolonged pressure half-time of mitral inflow. Based on the echocardiographic examination, the diagnosis was made as the mitral valve dysplasia concurrent with mitral valve stenosis and tricuspid valve dysplasia.

• Journal of The Institute of Information and Telecommunication Facilities Engineering
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• v.11 no.2
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• pp.29-33
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• 2012

ECG widely used in cardiac function test is a graph that is recorded by measuring the electrical impulses occurred in the heart. Normal ECG has the form of similar sections that are repeated, and each section has the information occurred in a heart beat. Thus, In order to make the correct diagnosis, correct grasp of the sections and formed analysis must be done. In this research, a system that detects the sections of ECG is proposed. The system is based on ECG stored in the form of files. The ECG can easily have a noise caused by an outside factor. The noise of ECG is easily caused by external factors. Through a band-pass filter, it can be removed. and then, to get this ECG without a noise, interval detection algorithm using R-peak is applied. The clean, intuitive interface will help the above functions to be used without any difficulties.