• 대한후두음성언어의학회지
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• 제8권1호
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• pp.49-53
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• 1997

Aberrations in VOT measures in apraxia of speech are indicative of speech motor programming impairment. In English, overlaps of VOT between voiceless and voiced plosives have been frequently observed in patients with apraxia of speech. Unlike English, Korean plosives constitute trichotomy in terms of manner of production, that is, voiceless aspirated /p', t', k'/ ; voiceless or voiced, weakly aspirated /p-b, t-k, k-g/ ; or voiceless, heavily aspirated /p, t, k/. In this spectrographic study, VOT measures during Korean plosives produced by a patient with apraxia of speech were compared to those by age- and gender- matching normal subjects. The results indicated that there were partial overlaps between VOT of /b, d, g/ and those of /p, t, k/, implying that the errors were phonetic in nature. In addition, larger VOT variabilities in apraxia of speech compared to the normals were noted.

• 음성과학
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• 제12권4호
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• pp.247-254
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• 2005

This study aimed at clarifing clinical effects of eight-step continuum treatment in a patient who showed apraxia of speech after stroke. The eight-step continuum treatment consisted of 8 steps and its clinical efficacy has been proven with American apraxic patients. However, it has not been clinically proven to be effective in Korean patients with apraxia of speech as of yet. Therefore, this study was conducted in an effort to provide preliminary clinical evidence regarding its effectiveness regardless of the linguistic differences between Korean and English. The therapy took place twice a week for 6 months, a total of 48 times. The results showed that the patient's receptive language was improved from 83% to 89% and 37% in accuracy, and expressive language from 15% to 37%. It seemed that spontaneous recovery did not playa role in his improvement since the study was conducted 2 years after the stroke. In addition, the improvement of expressive language was much greater(22%) than that of receptive language(6%), which implied that the therapy was effective in apraxia of speech because apraxia of speech is relatively confined to expressive ability, more specifically motor programming and sequencing.

• 말소리와 음성과학
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• 제6권3호
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• pp.33-40
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• 2014

The purpose of the study was to examine alternating motion rate and its variability in children with childhood apraxia of speech (CAS) compared to typically developing children. Six children with CAS aged 9-12 years old and 10 children who were age-matched participated in the study. This study measured tokens per second and variabilities of the rates during the production of /$p^*$ a/, /$t^*$ a/, and /$k^*$ a/. For variability measures of the rates, each participant was asked to repeat speech tasks three times and the average value of the rates and its standard deviation were obtained. The results revealed that the CAS group showed slower rate only at /$k^*$ a/ than the control group. The CAS group exhibited greater variability of AMR at all the tasks than the control group. The results suggested that variability of AMR might be a more distinctive speech feature to children with CAS than the rate of the speech task.

• 음성과학
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• 제12권2호
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• pp.101-108
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• 2005

Apraxia of phonation (AOP) has often been described as a feature of apraxia of speech or of severe non-fluent type of aphasia. Pure AOP is rare and, to our knowledge, only two cases have been reported. Brain lesion sites of the reported cases were not those sites known to be responsible for apraxia of speech. This study presents a case of AOP which resulted from the secondary stroke in the left corona radiata immediately following the first stroke in the left temporoparietal lobe. A 61-year old right-handed man shwoed a global type of aphasia after the first cerebral infarction, but was able to generate spontaneously some short fragments of speech. On the day after the first infarction, he suffered from the secondary infarction, leaving him a complete loss of voluntary phonation. He did not showed any significant change in language functions. Several occurrences of involuntary phonation were observed upon laughing or crying. He was also able to cough unintentionally. A vidoe-stroboscopic examination failed to reveal any evidence of structural and functional impairment in larynx. Although this case is not of pure form of AOP, AOP appeared after the secondary stroke without significant changes of language impairment since the first stroke. Therefore, AOP may be a consequence of the brain lesion from the secondary stroke even though we cannot rule out the possibility of an additive effect of the secondary to the first stroke.

• 대한음성학회:학술대회논문집
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• 대한음성학회 2003년도 10월 학술대회지
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• pp.125-127
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• 2003

The aim of the paper is to analyze prosodic characteristics in apraxia of speech and establish the fundamental sources in diagnosis of motor speech disorders. The sentences consist of two different types (declarative and interrogative) with different numbers of constituents which are one to three. The stimuli were constructed to assess apraxics speech with articulation and humming skills. The features of speech patterns were examined such as utterance duration, boundary tones, and etc. The results of the analysis are as follow: 1) In the interrogative sentences, the rising boundary tones appeared only in the humming tasks 2) the utterance duration is relatively shorter in the humming tasks than the speech with articulation.

• Journal of Genetic Medicine
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• 제19권2호
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• pp.111-114
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• 2022

Many monogenic neurodevelopmental disorders have been newly identified in recent years owing to the rapid development of genetic sequencing technology. These include variants of the epigenetic machinery - up to 300 known epigenetic factors of which about 50 have been linked to specific clinical phenotypes. Chromodomain, helicase, DNA binding 1 (CHD1) is an ATP-dependent chromatin remodeler, known to be the causative gene of the autosomal dominant neurodevelopmental disorder Pilarowski-Bjornsson syndrome. Patients exhibit various degrees of global developmental delay, autism, speech apraxia, seizures, growth retardation, and craniofacial dysmorphism. We report the first case of Pilarowski-Bjornsson syndrome in Korea, due to a de novo missense variant of the CHD1 gene (c.862A>G, p.Thr288Ala) in a previously undiagnosed 17-year-old male. His infantile onset of severe global developmental delay, intellectual disability, speech apraxia, and failure to thrive are compatible with Pilarowski-Bjornsson syndrome. We also noted some features not previously reported in this syndrome such as skeletal dysplasia and ichthyosis. Further studies are needed to discover the specific phenotypes and pathogenic mechanisms behind this rare disorder.

• 대한음성언어의학회:학술대회논문집
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• 대한음성언어의학회 2006년도 제25회 학술대회
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• pp.152-152
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• 2006

• 말소리와 음성과학
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• 제16권3호
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• pp.71-78
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• 2024

본 연구는 심리언어학적 관점에서 말 처리 단계를 음운부호화, 음운단기기억, 조음전환으로 구분하여 각 단계별 평가방법의 근간을 마련하고자 하였다. 이를 위해 2000년부터 2024년까지 발표된 연구 중 선정 기준에 따라 총 21편의 논문을 메타분석하였으며, 총 1,442명의 대상자를 포함하였다. 연구대상자는 일반집단, 난독증 집단, 말소리장애 집단, 언어지연 집단, 실행증+실어증 집단, 아동기말실행증 집단으로 구성되었다. 분석 결과, 음운부호화 오류 특성의 집단 간 차이에 대한 효과크기는 g=.46, 음운단기기억 오류 특성의 집단 간 차이에 대한 효과크기는 g=.57, 조음전환 오류 특성의 집단 간 차이에 대한 효과크기는 g=.63으로 나타났다. 이는 각각 대치 오류, 순서 및 반복 오류, 음소 첨가 및 유·무성음 간 대치 오류가 해당 능력 평가에 유용한 지표임을 시사한다. 본 연구는 말·언어장애를 다양한 시각으로 접근하는 데 기여하며, 오류 특성을 세부적으로 분석하여 말 언어장애의 원인을 보다 명확히 이해할 수 있는 방법을 제시한다. 향후 연구에서는 다양한 말·언어장애 집단을 대상으로 비단어 따라말하기 과제를 실시하고, 각 단계별 분석을 통해 심층적으로 살펴볼 필요가 있다. 이를 통해 제안된 분석 방법의 타당성을 검증하고, 말 언어장애 평가와 치료에 유용한 데이터를 제공할 수 있을 것이다.

• 대한음성학회:학술대회논문집
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• 대한음성학회 2007년도 한국음성과학회 공동학술대회 발표논문집
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• pp.265-269
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• 2007

This paper reports an compared acoustic analysis on speech produced by two Korean groups, normal and AOS, focusing on utterances of V-CV structures. Major concerns include: 1) types of errors (distortion/substitution) according to the place of articulation, 2) duration of each syllable, 3) VOTs of stop sounds, and 4) F1 and F2 of vowels. In terms of the differences in these phonetic characteristics between the two groups, we aim to clarify some characteristics of AOS and to provide fundamental criteria for diagnosing and evaluating the disease.

• 대한음성학회:학술대회논문집
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• 대한음성학회 2007년도 한국음성과학회 공동학술대회 발표논문집
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• pp.149-151
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• 2007

This study was designed to investigate fast ab/adduction rate of articulation valves in normal adults. The measurement of fast ab/aduction rate has traditionally been used for assessment, diagnosis and therapy in patients who suffered from dysarthria, functional articulation disorders or apraxia of speech. Fast ab/adduction rate shows the documented structural and physiological changes in the central nervous system and the peripheral components of oral and speech production mechanism. Fast ab/adduction rates were obtained from 20 normal subjects by producing the repetition of vocal function (/ihi/), tongue function (/t${\wedge}$/), velopharyngeal function (/m/), and labial function (/p${\wedge}$/). The Aerophone II was used for data recording. The results of finding as follows: average fast ab/adduction rates were vocal function(6.21cps), tongue function(7.42cps), velopharyngeal function(5.23cps), labial function (6.93cps). The results of this study are guidelines of normal diadochokinetic rates. In addition, they can indicate the severity of diseases and evaluation of treatment.