• Asian Pacific Journal of Cancer Prevention
• /
• v.16 no.14
• /
• pp.6055-6059
• /
• 2015

Background: Medication policy development in Thailand is continually promoting rational drug use. Letrozole, an endocrine therapy drug, is usually prescribed for post-menopausal status early and advanced stage breast cancer. After Ministry of Public Health announced Letrozole as compulsory licensed drug in 2009, more breast cancer patients can access to this drug at low cost especially those within universal coverage schemes. To ensure that Letrozole is rationally prescribed, the drug utilization study was conducted. Objectives: The aim of this study was to describe the appropriate use of Letrozole in breast cancer and the relationship between appropriate use and health benefit schemes. Materials and Methods: A retrospective study to evaluate use of Letrozole in breast cancer patients was performed for six months between January - June 2010 in seven regional cancer hospitals, Thailand. All prescriptions of Letrozole were identified from pharmacy dispensing databases and prescription papers. A medical record review was also performed to evaluate appropriate use referring to the drug use evaluation criteria. The approved criterion of this study was referred from the guideline of Thai National Formulary version 2010. Results: There were 681 prescriptions of Letrozole for 254 breast cancer patients with an average age of $58.6{\pm}10.0years$. The patients in universal coverage scheme (UCS), civil servant medication benefit scheme (CSMBS) and social security scheme (SSS) were 77.7%, 18.5% and 8.7% respectively. 10.6% were prescribed Letrozole for the first time. Letrozole were prescribed by oncologists (82.8%). The average number of tablets per prescription was $58{\pm}10$. Calcium supplements were prescribed concomitant with Letrozole for 19.4%. To assess drug use evaluation criteria, 45 prescriptions were excluded because of uncompleted clinical data, 636 prescriptions were evaluated. The study showed 86 prescriptions (13.5%) with inappropriate use including 6 (0.9%) not prescribed for estrogen receptor (ER) and/or progesterone receptor (PR) positive, 31 (4.9%) not prescribed for post-menopausal and 49 (7.7%) not prescribed for an appropriate duration. Appropriate use percentages in different health benefit schemes were similar, 85.7% of CSMBS, 86.4% of SSS and 86.7% of UCS. The relationship between health benefit scheme and appropriate use of Letrozole was not significantly different, ${\chi}^2$ (2, N = 636) = 0.081, p > 0.05. Conclusions: The study showed inappropriate use in breast cancer patients because of non-compliance with duration, menopausal status and hormone receptor requirements. To prescribe appropriate indication did not referred to the appropriate practice along the treatment. Drug use evaluation proved very useful for detecting the sign of inappropriate use and allows immediate feedback to the stakeholder for developing medication policy in the future. Importantly, there was no significantly difference in appropriate use of Letrozole across health benefit schemes.

• Biomedical Science Letters
• /
• v.25 no.4
• /
• pp.381-389
• /
• 2019

The physiological function test is the only patient contact area in the field of clinical laboratory. We need to recruit and encourage the experts due to requiring the expertise and long time for examination. However, there is currently no rule for estimating optimal workforce in the field of physiological function tests. The purpose of this study is to establish the basis of the studies for mid- to long-long term job creation in the field of ultrasound by evaluating the number of appropriate tests and appropriate workforce. We calculated the quantitative and qualitative workload for the number of appropriate tests and appropriate workforce using online questionnaire. All statistical analyses were performed using SPSS version 18.0 (SPSS Inc., Chicago, IL, USA). A total of 216 respondents were 48 (22.2%) male and 168 (77.8%) female. A total of 157 laboratories were 62 (39.5%) for echocardiography, 91 (58.0%) for the transcranial Doppler (TCD) and 4 (5.7%) for the carotid ultrasound. The mean number of appropriate tests was 10 ± 2 in the echocardiography, 9 ± 2 in TCD and 11 ± 2 in the carotid ultrasound. In addition, the number of laboratories required to recruit employees for appropriate workforce was 19 in echocardiography, 18 in TCD, and 0 in carotid ultrasound. The number of hospital required to recruit workforce were 7 primary hospitals, 22 secondary hospitals, 7 third hospitals. This study can be used as an important data as the first study at present time when the data on the workforce status and work environment of the ultrasonic laboratories is insufficient. Based on the quantitative and qualitative workloads, the number of appropriate tests and appropriate workforce can support mid- to long-long term job creation in the field of ultrasound.

• 한국체육학회지인문사회과학편
• /
• v.58 no.5
• /
• pp.201-217
• /
• 2019

The purpose of this study was to consider composition of the movement program for the elderly with dementia to develop visit-customized movement program. For the study, 20 experts were selected including 8 dance therapists, 2 dementia-specialized doctors, 5 physical education leaders of the elderly, and 5 geriatric care helpers. First Delphi data, which listed items, was used to analyze content. Second and third Delphi questionnaires, which evaluated importance in Likert scale, was used to calculate content validity rate, average, standard deviation, quartile, convergence degree, and concurrence degree of each composition. 46 core composition of movement program for the elderly, which were selected and highlighted by the experts, were departmentalized into 6 considered compositions of movement program. 7 required composition of movement program, 1 Appropriate frequency of 3 times in a week and 1 30 minutes for each exercise, 1 operation method, 5 appropriate exercise of rhythm expression, 4 appropriate aerobic exercise, 4 appropriate muscle exercises, 5 appropriate stretches, 3 appropriate partner exercises 4 Appropriate massages, 5 appropriate tools

• Korean Journal of Clinical Pharmacy
• /
• v.13 no.1
• /
• pp.18-28
• /
• 2003

An appropriate parent role model for alcohol, tobacco and other drug abuse prevention in adolescence was designed as part of a comprehensive effort to reduce the use of alcohol, tobacco and other drugs by underage youth. The content of the model offers a new and positive chemical health model. The model calls for development of a set of guidelines that can provide the framework for examining alcohol, tobacco and other drug use. The actions of adults in the community, especially parents, are very important factors in whether or not youth use chemicals. So these guidelines can be used to assist parents and other adults with questions such as, what can we say to young people about using alcohol, tobacco or other drugs except that it's against the law? At what age and times are discussions appropriate? What can we do to make our community a healthier place in which young people can make better decisions about alcohol, tobacco and other drug use? The model acknowledges and affirms the legal and appropriate use of alcohol and other drugs as well as supports the decision not to drink. It encourages participants to consider their own guidelines for using and not using alcohol and other drugs. The guidelines can also be used as the basis for early intervention when use is illegal, unhealthy or risky. It is important to note that the model affirms healthy and appropriate use as well as nonuse.

• English Language & Literature Teaching
• /
• no.3
• /
• pp.13-42
• /
• 1997

The purpose that the curriculum appropriate for the student's level pursues is to offer to a student the curriculum that can satisfy the student's interest, aptitude, and requirements. This curriculum has recently enforced all over the country, but the careful research and the plan for verification on its effect are required so that it may accomplish its purpose. This study, centered on the reading comprehension ability of Freshman English of the High School, aims to suggest a more desirable procedure for organizing and enforcing the curriculum appropriate for the students' level. In order to provide the best curriculum appropriate for the student's level. (1) the diagnosis of the individual student's level should be made first ; (2) the syllabus focused both on the grammar and on the communicative functions should be prepared ; (3) the teaching material on the basis of the syllabus should be selected considering the student's interest. and requirements. The new method of teaching-learning English should also be developed with the enforcement of the new curriculum discussed here. The curriculum appropriate for the student's level has many kinds of problems but these disadvantages should be overcome for providing the better educational system for the individual student.

• Journal of Appropriate Technology
• /
• v.7 no.2
• /
• pp.151-161
• /
• 2021

The application of appropriate technologies in a developing country is an opportunity to introduce green technology which may lead people to imagine a better life. This point is at the intersection of appropriate technology and sustainable development. This research focuses on Hatphain village where there is no clean water, sewage system, or power lines. Two environmental technologies (an unpowered water purification system, Ongdalsaem and an eco-toilet system, BeeVi toilet) were introduced, based on the concepts of the environmental self- sustainable village and feces Standard Money (fSM). We found that the Ongdalsaem was effective in reducing the concentration of nitrogen and lead in the water in Hatphain. The BeeVi water-free toilet was installed, allowing urine and feces to be separated and used as compost. We strived to spread ideas of sustainability using new eco-circulation experiences and encouraging learning about environmental technology through practical and playing facilities that residents managed themselves.

• Proceedings of the KIEE Conference
• /
• 2003.10b
• /
• pp.259-261
• /
• 2003

Generally, there is an input capacitor in front of PV(Photovoltaic) inverter in DG(Distributed Generation). This input capacitor mainly works in order to stabilize the PV output voltage. However, input capacitors, which are being used in domestic market are not well known about their appropriate value and also there is no information for selecting the suitable value of input capacitor. Therefore, the author suggests that the stand-alone PV inverter is considered to analyse appropriate value of input capacitor and then recommends the appropriate value of input capacitor through simulation.

• Proceedings of the Korean Institute of Building Construction Conference
• /
• 2016.10a
• /
• pp.79-80
• /
• 2016

In this study, we measured the relative density and the compressive strength in order to select the appropriate W/ B for the ultra-high strength concrete development. If W/B is lowered than the W/B of highest relative density, it was confirmed that the strength is lowered. However, if water is increased than the W/B of highest relative density, the relative density is decreased compressive strength was similar. The selection of the W/B of the lower than the highest relative density is not appropriate. Appropriate W/B is selected to be more than the maximum relative density of W/B.

• Korean Journal of Organic Agriculture
• /
• v.11 no.2
• /
• pp.1-21
• /
• 2003

Customary agriculture seeks to increase production and supply people with safe foods. Thus. the promotion and establishment of organic agriculture are required to reduce water and soil pollution caused by customary agriculture. Although organic agriculture is an agricultural technology system whose basic principle is organic water circulation in agronomic agriculture and livestock industry. the livestock raising sector has not been developed in Korean organic agriculture: hence the limited development of agronomic agriculture. This study therefore sought to develop a standardized model connected with organic livestock raising and organic agronomic agriculture to secure symmetric and continued development. Specifically, this study reviewed the technological and economic problems related to the development of a naturally circular standard model where organic agronomic agriculture and organic livestock raising are connected. Likewise, a model for calculating the appropriate quantity of fertilizers to be applied and appropriate number of livestock to be bred was proposed as important factors in the development of a regionally circular agriculture model, and an alternative to a system connecting the two factors suggested.

• Journal of Engineering Education Research
• /
• v.19 no.5
• /
• pp.25-34
• /
• 2016

The concept of the design thinking can be effective in engineering design process especially in developing the appropriate technology product. In this paper we analyze the student's design activities during the 'Creative and Integrated Design Academy for the other 90%' to solve the problems in the developing countries from the perspective of the design thinking. Based on this analysis we propose the direction of the creative and integrated design activities to solve the appropriate technology products and also the direction of the future engineering design process.