• BMB Reports
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• 제43권10호
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• pp.656-663
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• 2010

Amyloid precursor protein (APP), which is critically involved in the pathogenesis of Alzheimer's disease (AD), is cleaved by gamma/epsilon-secretase activity and results in the generation of different lengths of the APP Intracellular C-terminal Domain (AICD). In spite of its small size and short half-life, AICD has become the focus of studies on AD pathogenesis. Recently, it was demonstrated that AICD binds to different intracellular binding partners ('adaptor protein'), which regulate its stability and cellular localization. In terms of choice of adaptor protein, phosphorylation seems to play an important role. AICD and its various adaptor proteins are thought to take part in various cellular events, including regulation of gene transcription, apoptosis, calcium signaling, growth factor, and $NF-{\kappa}B$ pathway activation, as well as the production, trafficking, and processing of APP, and the modulation of cytoskeletal dynamics. This review discusses the possible roles of AICD in the pathogenesis of neurodegenerative diseases including AD.

• 디지털산업정보학회논문지
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• 제16권1호
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• pp.41-54
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• 2020

In this paper, it will study various problems such as personal information infringement from when using various useful Apps in the Smartphone environment. It also researched the vulnerabilities Mobile Apps and the risks of personal information leakage when using Smartphone information to decrease threat and find solution. In the second chapter, it will check the existing Mobile App related Apps. In the third chapter, it will check the threats and major factors that caused by the leakage of personal information which related to the app. Then it will suggest solution and end with conclusion. This paper also looked at various problems that caused by illegal adverse effect from illegal personal information collection. Then it researched and made suggestion to make consideration on safety of personal information and privacy infringement that threat to personal information For safety of mobile banking, it proposed a safety method to separate and manage the code which has the core logic which required to run the App. For safety of direction App, when running the direction App, even if the information is collected, location information for unauthorized accessed will encrypt and store in DB, so that access to personal information is difficult. For delivery App environment, by using the national deliver order call center's representative phone to receive a telephone order then, the customer information is delivered to the branch office when it receive order and it will automatically delete information from the server when the delivery is completed by improving DB server of order. For the smart work app environment, the security solution operates automatically by separating and make independent private and work areas. Then it will suggest initialization for company's confidential business information and personal information to safe from danger even if loss.

• 한국임상약학회지
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• 제33권1호
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• pp.51-61
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• 2023

Background: Mobile applications (apps) on dietary supplements can increase consumers' access to information. However, it can lead to indiscriminate use of dietary supplements. This study aims to systematically review dietary supplement apps released in English and Korean and evaluate the quality of those apps. Methods: Through the app stores, apps on dietary supplements were systemically searched and examined. Two independent evaluators evaluated the apps and presented a mean score using the Mobile App Rating Scale (MARS). The correlation between MARS scores, user and evaluator ratings, and the number of secondary features of the apps were analyzed. Results: Of the 2,772 dietary supplement apps identified, 17 apps were included according to the selection criteria. The mean MARS score was 3.28 (standard deviation: 0.29) out of 5. Apps had higher scores in aesthetics and functionality dimensions, while engagement and information dimensions had lower scores. There was a positive correlation between the number of app downloads and information among MARS dimensions. The subjective evaluation also correlated with the information dimension. There was a positive correlation between the secondary features of the apps and MARS total score as well as the engagement dimension. Conclusion: The dietary supplement apps need to be managed at a higher level of quality to provide safe and reliable information to consumers. Especially, quality on information and engagement dimensions can be improved. Involvement of healthcare professionals in the app development, management with adequate referencing of information, and use of secondary features for enhanced user engagement can be helpful.

• Korean Journal of Acupuncture
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• 제40권1호
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• pp.1-12
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• 2023

Objectives : This study aims to provide information regarding the status and quality of mobile applications (MAs) using self-acupressure by performing a systematic review. Methods : We conducted comprehensive searching on five international databases and two app markets from inception to July 31, 2022 to identify MAs using self-acupressure. We analyzed the characteristics of each MA regarding the name of the MA, registered app markets, target symptoms, developers, the year and country of development, cost, target age, media function, and expertise. We assessed the quality of each MA using Mobile Application Rating Scale (MARS). Results : We identified a total of 30 MAs using self-acupressure (25 MAs from the app market and 6 MAs from clinical studies, with 1 MA in common). 17 out of 24 MAs from the app market provided self-acupressure regimens for various symptoms and the others provided regimens for specific symptoms such as memory, anxiety, depression, asthma, allergy, low back pain, and headache. 14 developers were reported. 23 MAs were developed after 2013. The largest number of MAs were developed in the United States. The target age group of 12 MAs was above the age of 3, and that of 11 MAs was above the age of 12. 14 MAs provided multimedia functions such as videos. 13 MAs provided information of expertise. From clinical studies, only 3 out of 6 MAs were accessible through the app market. 4 MAs were developed by the researchers of the study. In terms of MARS, the score of MAs from the app market was higher than that of MAs from clinical studies in both objective and subjective evaluation areas. Conclusions : This study summarizes the characteristics of MAs using self-acupressure. More MAs using self-acupressure should be developed and further clinical research for MA on each symptom and disease is warranted for the diversification of MA fields using self-acupressure.

• 한국산업융합학회 논문집
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• 제27권2_2호
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• pp.445-456
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• 2024

This study aims to suggest service improvement opportunities by analyzing user review data of the top three OTT service apps(Netflix, Coupang Play, and TVING) on Google Play Store. To achieve this objective, we proposed a framework for uncovering service opportunities through the analysis of negative user reviews from OTT service providers. The framework involves automating the labeling of identified topics and generating service improvement opportunities using topic modeling and prompt engineering, leveraging GPT-4, a generative AI model. Consequently, we pinpointed five dissatisfaction topics for Netflix and TVING, and nine for Coupang Play. Common issues include "video playback errors", "app installation and update errors", "subscription and payment" problems, and concerns regarding "content quality". The commonly identified service enhancement opportunities include "enhancing and diversifying content quality". "optimizing video quality and data usage", "ensuring compatibility with external devices", and "streamlining payment and cancellation processes". In contrast to prior research, this study introduces a novel research framework leveraging generative AI to label topics and propose improvement strategies based on the derived topics. This is noteworthy as it identifies actionable service opportunities aimed at enhancing service competitiveness and satisfaction, instead of merely outlining topics.

• 지능정보연구
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• 제21권2호
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• pp.1-18
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• 2015

협업 필터링은 학계나 산업계에서 우수한 성능으로 인해 많이 사용되는 추천기법이지만, 정량적 정보인 사용자들의 평가점수에만 국한하여 추천결과를 생성하므로 간혹 정확도가 떨어지는 문제가 발생한다. 이에 새로운 정보를 추가로 고려하여, 협업 필터링의 성능을 개선하려는 연구들이 지금까지 다양하게 시도되어 왔다. 본 연구는 최근 Web 2.0 시대의 도래로 인해 사용자들이 구입한 상품에 대한 솔직한 의견을 인터넷 상에 자유롭게 표현한다는 점에 착안하여, 사용자가 직접 작성한 리뷰를 참고하여 협업 필터링의 성능을 개선하는 새로운 추천 알고리즘을 제안하고, 이를 스마트폰 앱 추천 시스템에 적용하였다. 정성 정보인 사용자 리뷰를 정량화하기 위해 본 연구에서는 텍스트 마이닝을 활용하였다. 구체적으로 본 연구의 추천시스템은 사용자간 유사도를 산출할 때, 사용자 리뷰의 유사도를 추가로 반영하여 보다 정밀하게 사용자간 유사도를 산출할 수 있도록 하였다. 이 때, 사용자 리뷰의 유사도를 산출하는 접근법으로 중복 사용된 색인어의 빈도로 산출하는 방안과 TF-IDF(Term Frequency - Inverse Document Frequency) 가중치 합으로 산출하는 2가지 방안을 제시한 뒤 그 성능을 비교해 보았다. 실험결과, 제안 알고리즘을 통한 추천, 즉 사용자 리뷰의 유사도를 추가로 반영하는 알고리즘이 평점만을 고려하는 전통적인 협업 필터링과 비교해 더 우수한 예측정확도를 나타냄을 확인할 수 있었다. 아울러, 중복 사용 단어의 TF-IDF 가중치의 합을 고려했을 때, 단순히 중복 사용 단어의 빈도만을 고려했을 때 보다 조금 더 나은 예측정확도를 얻을 수 있음도 함께 확인할 수 있었다.

• International Journal of Knowledge Content Development & Technology
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• 제11권1호
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• pp.85-111
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• 2021

This study aims to analyze users' assessment of electronic libraries in the mobile app market and promote service improvement based on this. To this end, the basic background and purpose of the research, research method, and research scope were first set, and the relevant literature and empirical prior studies were analyzed. Next, users' evaluations of electronic libraries were collected and analyzed from Google Play Store. Based on the results analyzed, measures to improve the quality of electronic libraries were discussed. Based on the results of the study, the following improvement measures are proposed. Need for systemic improvement and stabilization. Provision of applications suitable for multi-device environments. Resumption of services after systematic inspection after updating. Simplification of sign up, log in, and authentication procedures. User support through real-time chat. Introduction of a detailed assessment of reviews. Provision of guidance and user manual for electronic libraries. Improvements to expand user convenience, and Securing differentiation from other similar services.

• PNF and Movement
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• 제22권2호
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• pp.159-170
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• 2024

Purpose: This study suggests observational gait analysis (OGA) strategies for therapists with limited experience in clinics in evaluating patients with stroke during walking. Methods: The proposed model was the mnemonic STEP APP, whose initials refer to the process of OGA for clinical reasoning and decision-making by identifying problems during walking in patients with stroke. Results: STEP APP stands for step (S), tibia (T), events (E), phases (P), ankle (A), problems (P), and priority (P). It serves as a procedural guide for OGA in patients with stroke walking on the ground. Conclusion: This review suggests a simple evaluation of gait using OGA that can be used by therapists who have less experience and difficulty in evaluating patients with stroke during walking. However, it is important to consider the front and back views of motion as well as motion in the transverse plane in order to analyze problems accurately. Furthermore, small joint problems, such as those in the foot, should be considered when evaluating patients with stroke during walking.

• 한국비블리아학회지
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• 제22권1호
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• pp.171-191
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• 2011

본 연구는 스마트폰과 앱에 관한 정보통신기술의 원리를 소개하고 스마트폰 앱을 활용한 국내외 대학도서관의 대표적인 서비스 사례들을 살펴보고 미래 도서관의 모바일서비스 예측에 의거 바람직한 스마트폰 앱기반의 모바일 서비스 전략을 제시하였다. 국내 대학도서관에서 스마트폰 앱기반 모바일서비스를 활성화시키기 위해서는 첫째, 모바일 웹과 앱을 연계한 하이브리드 서비스 체제를 구축할 필요가 있다. 둘째, 도서관서비스에 적용할 스마트폰 앱 평가 원칙을 수립한다. 셋째, 대학도서관의 마케팅과 교육서비스에 앱을 개발하거나 활용한다. 넷째, 앱정보에 대한 앱서지 정보서비스를 제공할 것을 제안하였다.

• 인터넷정보학회논문지
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• 제20권3호
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• pp.111-117
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• 2019

본 연구는 선행 연구 분석과 전문가 심층 인터뷰를 통해 스마트폰 기반 간편결제 서비스의 사용자 확산 정도를 결정하는 요인을 범용성, 보안성, 사용 편의성, 사용자 경제성, 가맹점 경제성으로 도출하였다. 또한 전문가 설문을 AHP 기법으로 분석한 결과, 각 요인별 중요도는 보안성, 범용성, 사용 편의성, 사용자 경제성, 가맹점 경제성 순으로 나타났다. 그러나 보안 관련 법규 준수 의무로 인해 보안성은 모델 간 평가 결과의 차이가 크지 않았고, 상대적으로 편차가 큰 범용성이 실질적으로 간편결제 서비스의 확산을 결정하는 요인임을 규명하였다. 또한 요인별 가중치를 주요 간편결제 서비스 모델인 MST, NFC, APP 카드에 적용한 결과, MST의 확산 가능성이 가장 높음을 확인하였다.