• Title/Summary/Keyword: Anti-Form

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Anti-DNA Autoantibodies from on MRL/Ipr Mouse

  • Park, Jeong-Soo;Kim, Young-Tai;Lee, Chan-Hee;Youn, Jung-Koo;Jang, Young-Ju
    • Animal cells and systems
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    • v.2 no.3
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    • pp.371-375
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    • 1998
  • Twenty-one monoclonal anti-DNA autoantilndies were produced by fusing spleen cells from an autoimmune MRL/lpr mouse with SP2/0 myeloma cells. Hybridomas generated by the fusions were chosen for cloning on the basis of DNA binding by supernatant antibody. Each monoclonal antibody was purified to homogeneity and analyzed for the heavy and light chain isotypes and the binding specificity for single-stranded DNA, double-stranded DNA, and RNA. Sequence specificities and isoelectric points of the antibodies were also examined. All of the antibodies were lgG and tended to bind to both single-stranded and double-stranded DNA with a preference for the double-stranded form. Some of them also bound to RNA. Isoelectric points of the antibodies were shown to be high. The antibodies described in this report have characteristics of pathogenic anti-DNA antibodies.

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Dynamical anti-reset windup method for saturating control systems with multiple controllers and multiloop configuration and its application to motor control systems (다중 제어기 및 다중 루우프로 구성된 포화제어시스템의 동적 리셋 와인드엎 방지 방법과 모터제어에의 응용)

  • Park, Jong-Gu;Park, Chong-Ho
    • Journal of Institute of Control, Robotics and Systems
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    • v.4 no.2
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    • pp.141-150
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    • 1998
  • This paper presents a dynamical anti-reset windup (ARW) compensation method for saturating control systems with multiple controllers and/or multiloop configuration. By regarding the difference of controller states in the absence and presence of saturating actuators as an objective function, the dynamical compensator which minimizes the objective function is derived in an integrated fashion. The proposed dynamical compensator is a closed form of plant and controller parameters. The resulting dynamics of compensated controller reflects the linear closed-loop system. The proposed method guarantees total stability of the resulting system. The effectiveness of the proposed method is illustrated by applying it to a servo motor control system. The paper is an extension of the results in Park and Choi[1].

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Anti-wrinkle Effect of Herbal Medicine Plant and Its Applications in Cosmetics

  • Park, Young-Ho
    • Journal of the Korean Chemical Society
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    • v.60 no.4
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    • pp.235-238
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    • 2016
  • Mt. Jiri located in the southwestern part of Korea is a treasure trove of wild medicinal plants. More than 1200 species currently classified as herbs are grown or cultivated in the area. Recently, safflower has attracted interest because of its ability to control fine wrinkle formation on the neck. The objective of this study therefore was to determine whether the active ingredient of safflower could be used in the form of an extract to reduce wrinkle formation in individuals aged 30 to 59 years. In particular, this study was aimed at determining the extract’s elastase activity and anti-oxidant effect by using DPPH assay in vitro and evaluating the anti-wrinkle efficacy of different types of safflower extracts in improving fine wrinkles on the neck. This study will provide a basis for future studies to develop safflower extracts using advanced composition technology and contribute to the development of the herbal cosmetics industry.

The Reduction Effect of Yeast Hydrolysate SCP-20 on Premenstrual Syndrome (효모 가수분해물 SCP-20의 월경전 증후군 감소효과)

  • 유광원;오성훈;최윤석;황원준;서형주
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.30 no.5
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    • pp.1000-1003
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    • 2001
  • A yeast hydrolysate SCP-20 with anti-stress and mitigative effects for premenstrual syndromes (PMS) was composed with crude protein (57.5%) and carbohydrates (28.1%). For the investigation of anti-stress effect in the immobilization stressed rats, the weights of spleen, thyroid and kidney in the group of SCP-20 sdministration were significantly different from those in the group not given SCP-20. Total power (TP), suppression indicator of stress, was obtained from frequency of heart rate variability. TP was changed by the administration of SCP-20 suggesting that SCP-20 has the autonomous nervous control effect. In premenstrual assessment form(PAF), the administration of SCP-20 reduced the intensity of somatic symptoms, emotional symptoms, and behavioral symptoms.

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The Expression of Materiality and Formlessness in Fine Art and Fashion (순수미술과 패션 속의 물질성의 표현과 무정형성 경향)

  • Yun, Su-Jeong;Kim, Min-Ja
    • Journal of the Korean Society of Costume
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    • v.57 no.6 s.115
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    • pp.122-134
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    • 2007
  • Fine art and fashion have influences on each other since both of them are the part of a culture. The similar patterns of fine art and fashion can be found either in the same period or in the different time. To find out this fact in the forms or content, this study researched into the fine art and fashion of 1960s and into recent year's fashion to see the revivals. In 1960s, fine art and fashion laid emphasis on the materiality of material itself, therefore both fine art and fashion have the tendency of formlessness and disorder in form. It ran be said that the socio-cultural background of this phenomenon in 1960s was mainly caused by the young generation called Hippies. They became a large influential social group that has a huge impact on overall culture in 1960s. As a result, this study firstly found that the fine art and fashion had common formative features and content in 1960s. Secondly, fashion since 1990 repeats the similar features in form like the Post-minimal tendency in fine art in 1960s. The similar features can be described as: artworks have the tendency of the formlessness and disorder in appearances; various materials were newly used to form a work, which had never been used in traditional artworks; new methods such as hanging, layering and knotting were applied to show the maximum expression of the materiality. However, unlike the fashion of 1960s, the Post-minimal tendency in fashion since 1990s doesn't symbolized freedom or peace, or opposition to the war anymore. Instead, only the formative elements were revived and reproduced and the formless tendency became one of the recent fashion trends.

Anti-mold Effectiveness of Neonicochid Type Wood Preservative (네오니코치드계 목재보존제의 방곰팡이 효력)

  • Lee, Dong Heub;Lee, Jong Shin
    • Journal of the Korean Wood Science and Technology
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    • v.42 no.1
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    • pp.41-48
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    • 2014
  • To development of the low toxic preservatives, we prepared 29 kinds of chemicals using dinotefuran of low toxic insecticide, IPBC and propiconazol of fungicide, and clove oil has fungicidal activity, but is harmless to humans. It was conducted to investigate the inhibitory effectiveness of mycelial growth and anti-mold effectiveness to treated PDA medium and wood specimen with prepared chemicals. It was not showed anti-mold effectiveness that solvent and emulsifier form preservatives. Therefor, we thought that only four component, dinotefuran, IPBC, propiconazol and clove oil, has anti-mold effectiveness. In the PDA medium test, the preservative which has much IPBC showed high anti-mold effectiveness. By the wood specimen test, it was known that many prepared preservatives which showed good inhibitory effectiveness of mycelial growth in the PDA medium test, have not anti-mold effectiveness. Of all prepared preservatives in this study, only three preservatives containing dinotefuran and IPBC, or adding clove oil appeared the excellent anti-mold effectiveness.

A young child of anti-NMDA receptor encephalitis presenting with epilepsia partialis continua: the first pediatric case in Korea

  • Kim, Eun-Hee;Kim, Yeo Jin;Ko, Tae-Sung;Yum, Mi-Sun;Lee, Jun Hwa
    • Clinical and Experimental Pediatrics
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    • v.59 no.sup1
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    • pp.133-138
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    • 2016
  • Anti-N-methyl D-aspartate receptor (anti-NMDAR) encephalitis, recently recognized as a form of paraneoplastic encephalitis, is characterized by a prodromal phase of unspecific illness with fever that resembles a viral disease. The prodromal phase is followed by seizures, disturbed consciousness, psychiatric features, prominent abnormal movements, and autonomic imbalance. Here, we report a case of anti-NMDAR encephalitis with initial symptoms of epilepsia partialis continua in the absence of tumor. Briefly, a 3-year-old girl was admitted to the hospital due to right-sided, complex partial seizures without preceding febrile illness. The seizures evolved into epilepsia partialis continua and were accompanied by epileptiform discharges from the left frontal area. Three weeks after admission, the patient's seizures were reduced with antiepileptic drugs; however, she developed sleep disturbances, cognitive decline, noticeable oro-lingual-facial dyskinesia, and choreoathetoid movements. Anti-NMDAR encephalitis was confirmed by positive detection of NMDAR antibodies in the patient's serum and cerebrospinal fluid, and her condition slowly improved with immunoglobulin, methylprednisolone, and rituximab. At present, the patient is no longer taking multiple antiepileptic or antihypertensive drugs. Moreover, the patient showed gradual improvement of motor and cognitive function. This case serves as an example that a diagnosis of anti-NMDAR encephalitis should be considered when children with uncontrolled seizures develop dyskinesias without evidence of malignant tumor. In these cases, aggressive immunotherapies are needed to improve the outcome of anti-NMDAR encephalitis.

Antioxidative Activity and Therapeutic Effect of the Hydrogel Preparations of Scutellariae Radix and Zingiberis Rhizoma on Dermatitis (황금 및 생강 복합 수용성겔 제제의 항산화 활성 및 피부염 치료효과)

  • Yang, Jae-Heon;Kim, Dae-Keun;Yun, Mi-Young;Ahn, Jae-Kyu
    • Journal of Pharmaceutical Investigation
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    • v.36 no.4
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    • pp.253-262
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    • 2006
  • This study was performed to investigate the effects of treatment for dermatitis using the herbal gel preparations. Scutellariae Radix(SR) and Zingiberis Rhizoma(ZR) were used for the purpose of herbal preparations. Baicalin, baicalein are the ingredients of SR, having biological effects like anti-inflammatory, anti-oxidative, anti-bacterial and antiallergic action. 6-Gingerol is one of the ingredients of ZR having biologicai effects like anti-inflammatory and analgesic action. The three types of hydrogels(SRE, SRH, SZH) were formulated with Carbopol 940, Labrasol, Triethanolamine etc. Baicalin was hydrolysed to baicalein by $\beta$-glucuronidase for the purpose to increase rate of skin permeation. Content of ingredients by HPLC determination, rate of skin permeation using Franz type diffusion cell, anti-oxidative activity for the free radical, hydroxyl radical, superoxide, anti-inflammatory by using carrageenan injection, efficacy on the dermatitis induced by 2,4-dinitro-chlorobenzene(DNCB) were experimented. Baicalein showed higher permeability than baicalin, so it is considered that baicalein was more suitable form than baicalin for transdermal absorption by its lipophilic property. In the anti-oxidative experiments, SZH gel was the most effective scavenging activity than the other gels in all experiments. In anti-inflammatory test, SRM and SZH gel more decreased edma rapidly than SRE gel. In case of using SZH gel, treatment period for the dermatitis was more declined than that of other gel groups. These results suggests that the SZH hydrogel could be suitable preparations for the treatment of dermatitis.

Robust tracking controller design for a load variation (부하변화에 견실한 추적 제어기 설계)

  • 김광태;정구락;김재환;박원철;박래석
    • 제어로봇시스템학회:학술대회논문집
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    • 1991.10a
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    • pp.629-632
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    • 1991
  • Load Variation effects on the system driving performance. Therefore, this paper presents as a application example of Anti-windup method using general incremental form for a gun servo system of load variation involved. Also, this method can be easily implemented compared to gain scheduling technique.

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A Study on Perception of Alcoholic Beverage among Women and Development of Anti-Oxidant Beer Natural Ingredients (국내 성인 여성의 음주 인식과 형태 및 천연 소재를 활용한 항산화 맥주 개발에 관한 연구)

  • Shin, Bok-Hi;You, Seon-Hee
    • Journal of the Korean Applied Science and Technology
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    • v.34 no.4
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    • pp.924-937
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    • 2017
  • For the study, 366 copies of questionnaire were distributed among and collected from Korean women in their 20s to 60s between April and May 2016. To investigate the utility of anti-oxidant beers that contain extracts of natural substance respectively, the anti-oxidantive activity were measured and preference for anti-oxidant craft beers was surveyed among the subjects. The result suggested that the subjects had positive perception toward drinking, Korean adult women highly prefer beer among different types of alcoholic beverage, and the form of drinking changed according to the stamina, mood, situation, place, and company. Also, natural substance extracts showed high levels of antioxidant effects and, in the survey on preference for craft beers, the aronia group scored higher than other groups. The findings in this study suggest, for Korean adult women, beer with anti-oxidant ingredients can be beneficial for skin and overall health. Also, the findings can be used as basic data related to drinking among adult women and development of anti-oxidant beer. The Journal of Digital Policy & Management. This space is for the abstract of your study in English.